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The map label for this gene is mlaA [H]

Identifier: 82701809

GI number: 82701809

Start: 775331

End: 776029

Strand: Direct

Name: mlaA [H]

Synonym: Nmul_A0676

Alternate gene names: 82701809

Gene position: 775331-776029 (Clockwise)

Preceding gene: 82701808

Following gene: 82701810

Centisome position: 24.35

GC content: 53.36

Gene sequence:

>699_bases
GTGCCGAACGATCAGAGCGCAGACTATAGGGATTCGATCGATCCATTCGAGGGTATCAATCGCAAGTTTTACACTTTTAC
CGATGTGATCGACCGGAAACTCATCGAGCCGGTGGCGGAGGTTTATATTGACCACGTCCCCACCCGGGTGCAGCGCTCCG
TCGGGAATTTTTATGACAATATCCAGTACCCGAACGTCGTCCTGAATGATTTCCTGCAAGGCAAGGTACGCCAGGGATTT
CGTGACGGGCTGCGCTTCGTCGTCAATTCCACCCTTGGTATCGCCGGGCTCTTTGATCCGGCTTCTTCCATGGGCTTCAC
CCAGCATGATGAAGATTTCGGACAAACGCTGGGGGTGTGGGGGGTGAATGCAAGCACTTACCTTTTTGTTCCCTTGCTTG
GGCCTAGCAGCAATCGCGATGTTGCCTCATATCCAGTCGCTCTATTTACGAATGTCCTTTTCTATATCGGAACTTATGTG
ATCGGAGCCCCCGTCACCGTGCCGCTTTCCGTTCTGGGTGTCATTGACAAGCGGGCAAGATTGTCCGGCCCCATGAAAAT
CCGGGATGAAGCAGCGCTTGAGCCTTATCTGTTCGTACGCGACGCCTACTTGCAGCAGCGCAAGCATTTGATTTACGACG
GAAATCCCCCTCCCGAGATTTATGACGATCCCGCGGAGGAGGAGCCTGTGACTAAGTAG

Upstream 100 bases:

>100_bases
TCATAAACTCGTGACATATAACCGTATTACTGTCCTCTTGCTGCTTGCCTGCACAATGCTGGTCACAGGATGTGCTACTA
CCCGCACGCAGGGATCGACA

Downstream 100 bases:

>100_bases
CGTCCTGTCCTATTAGTCGCCTGTTGCATTCGATTGGGGCTGAAGGATTAGGCAGCGTGAGCGTATCCCCTTGAAATCCT
GCAAACGTGAGGCTGAGCAG

Product: VacJ-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MPNDQSADYRDSIDPFEGINRKFYTFTDVIDRKLIEPVAEVYIDHVPTRVQRSVGNFYDNIQYPNVVLNDFLQGKVRQGF
RDGLRFVVNSTLGIAGLFDPASSMGFTQHDEDFGQTLGVWGVNASTYLFVPLLGPSSNRDVASYPVALFTNVLFYIGTYV
IGAPVTVPLSVLGVIDKRARLSGPMKIRDEAALEPYLFVRDAYLQQRKHLIYDGNPPPEIYDDPAEEEPVTK

Sequences:

>Translated_232_residues
MPNDQSADYRDSIDPFEGINRKFYTFTDVIDRKLIEPVAEVYIDHVPTRVQRSVGNFYDNIQYPNVVLNDFLQGKVRQGF
RDGLRFVVNSTLGIAGLFDPASSMGFTQHDEDFGQTLGVWGVNASTYLFVPLLGPSSNRDVASYPVALFTNVLFYIGTYV
IGAPVTVPLSVLGVIDKRARLSGPMKIRDEAALEPYLFVRDAYLQQRKHLIYDGNPPPEIYDDPAEEEPVTK
>Mature_231_residues
PNDQSADYRDSIDPFEGINRKFYTFTDVIDRKLIEPVAEVYIDHVPTRVQRSVGNFYDNIQYPNVVLNDFLQGKVRQGFR
DGLRFVVNSTLGIAGLFDPASSMGFTQHDEDFGQTLGVWGVNASTYLFVPLLGPSSNRDVASYPVALFTNVLFYIGTYVI
GAPVTVPLSVLGVIDKRARLSGPMKIRDEAALEPYLFVRDAYLQQRKHLIYDGNPPPEIYDDPAEEEPVTK

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=218, Percent_Identity=32.5688073394495, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 26076; Mature: 25945

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNDQSADYRDSIDPFEGINRKFYTFTDVIDRKLIEPVAEVYIDHVPTRVQRSVGNFYDN
CCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
IQYPNVVLNDFLQGKVRQGFRDGLRFVVNSTLGIAGLFDPASSMGFTQHDEDFGQTLGVW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHCCCCCCCHHHHHHHCCC
GVNASTYLFVPLLGPSSNRDVASYPVALFTNVLFYIGTYVIGAPVTVPLSVLGVIDKRAR
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LSGPMKIRDEAALEPYLFVRDAYLQQRKHLIYDGNPPPEIYDDPAEEEPVTK
CCCCCEECHHHHCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PNDQSADYRDSIDPFEGINRKFYTFTDVIDRKLIEPVAEVYIDHVPTRVQRSVGNFYDN
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
IQYPNVVLNDFLQGKVRQGFRDGLRFVVNSTLGIAGLFDPASSMGFTQHDEDFGQTLGVW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHCCCCCCCHHHHHHHCCC
GVNASTYLFVPLLGPSSNRDVASYPVALFTNVLFYIGTYVIGAPVTVPLSVLGVIDKRAR
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LSGPMKIRDEAALEPYLFVRDAYLQQRKHLIYDGNPPPEIYDDPAEEEPVTK
CCCCCEECHHHHCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]