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The map label for this gene is yciR [C]

Identifier: 82701763

GI number: 82701763

Start: 715310

End: 717409

Strand: Direct

Name: yciR [C]

Synonym: Nmul_A0630

Alternate gene names: 82701763

Gene position: 715310-717409 (Clockwise)

Preceding gene: 82701762

Following gene: 82701766

Centisome position: 22.46

GC content: 53.24

Gene sequence:

>2100_bases
ATGAAAAAAGAGTTTGAATTGAATTACTCACTCTCCGTGCTGAAAGCAGCGATAGAGGCAACGGTTGACGGCCTTCTGGT
TACAGATAGACGGGGCAAGGTGCTTTGCTACAACCAGCTTTACGTGAATATGTGGCCCATTCCAGGTGAACTCCTGGCTC
ATGCGAGACACCAGGCAATCCTGGGCTATTGTGCCGGGCAATTAAGAGATCCCGAGCAATTCCTGCGCTCAATCGAGGAA
ATTTATGCGACCTTGGCACCAGAAAGCTTTAATGTCTTTGAATTTCGCAATGGCAGGGTATTTGAGCGATGTGCAAAAGT
CAAAACTCTGGAAGGATCTGACATCGTGCTCGTTTGGAGCTTCAGGGACATTACTGAACGAAGACAGGGGGAGAGCTACA
AAGCGCAGTTAGCGGCAATCGTCGAGTCCTCGAATGACGCCATCATTGTCAAGGATCTCAACGGCATTATTACCGGTTGG
AATGCCGCGGCAGAAGAGCTTTTTGGATATCGTTCCGGCGAAATAATAGGCTCTTCCATATTGACGCTGATTCCGCCCGA
CCGCCTGGAGGAAGAGGACAGAATCATGAACCTCGTCAAGAGCGGGAAACGCACGGACCATTTTGAAACCGTGCGATGGG
GGAAGGGCAAGAAATCGATTGATGTCTCCGTCACGATATCCCCGGTGAAGGATAGCGCCGGCAATATCATTGGTGCATCA
AAGATTGCACGGGATATCACTCAGCGCAAGGAATCACAAGAACGTATCGAGTATCTCGCCCATTACGATTTGCTGACCGG
CCTGCCCAACCGCGCGCTGTTCACCGACCGCATGAGGATCGCGATCGAGAACGCCAGCCGCTATGCCTTCCGGCTGGCAT
TACTATTCGTGGACCTCGATCGCTTCAAGCTGATCAACGATTCGCTTGGTCATGCAATCGGCGACAAGCTGCTCAAGGCA
GTTGCAGAGCGCATGCAGTCCACGGTTCGCCAGGCGGATACAGTCAGTCGGCTGGGGGGGGATGAGTTCGTTGTCCTGCT
GGGCCGGATTCATACAGCGACGGAGGCGGCGCGAGTTGCCGAGAAGCTTATTGCAGTCTTGTCTCAGCCCTATCAAATAG
AACAGCATGAACTCTTGCTGACCGCAAGCGTCGGGATCAGCATTTATCCGGATAGCGGTAAGGACGTCAACAGCTTGATG
CGCAATGCCGACGTTTCGATGTATTCGGCCAAGGGGCAGGGCAGGAACCGCTACCAGTTCTATTCTGAAGATTTGACTTC
CGGCGCAGACGAGCGGCTCAGGCTGGAATACGACCTGCGCAGCGCTCTTGCGCGTGACGAAATTTTCCCGGTCTACCAGC
CACAGCTGGAGCTTGCTACCGGACGCGTGGTAGGCGTGGAGGCGCTCATGCGCTGGAAGCACCCCGAGCGAGGGCTAGTC
TCCCCTGCAAGCTTTATTCCCGTAGCCGAGGACAGCGGTTTGATTCTGTCTCTGGGGGAGCACATCCTGAGGGAATCCTG
CCTGCAGGCACGCCAATGGCATGAGCAGCAGGGATTCGAGGGAACAATCGCGGTAAACGTTTCAGCAGTACAATTCCGTC
AGAATGATTTCACGGATGTTGTACTGCGCGCACTTGCAGACAGCGGTCTTTCGCCAGAATGCCTGGAACTCGAGTTGACC
GAAAGTGTGGTGATGCATGGAGTGGAATCGGCTACACAGAAAATGTGCTTCCTGGAGTCCCGGGGTATAAAACTGGCTAT
TGACGATTTCGGTACCGGCTATTCCAGTTTGTCCTATTTGCGGCAATTTGCCATTGACCGGCTAAAAATAGATCGAAGCT
TCGTTCGTGATCTCCCCCAGGACACTGATGCCAAAGCTATTATTCGCGCCACTGTGGCAATGGGGCGCAGCCTTGGCTTA
CGTGTAATGGCGGAAGGTGTAGAGACGGAAGGGCAAGCGGAGTATTTGCGAAGCGTTCAATGCGATGAAAGCCAAGGCTA
TCTGTATGCAAGGCCAATGAGGCCAGATGATTTTGAAGCCTGGCTAAAGGGTAGGAAGCCAGATTTTAGGGGCTCGCGCT
ATCAAATGGCGCAATCGTAA

Upstream 100 bases:

>100_bases
GTGCCCATTAAATATGTTTATATCGAAAATCACAGATTGATTCGTCCCGATCAGGAAGAGGAAAGGACAGATAGAGCATG
GATAAGAAAAACGAAAAAGC

Downstream 100 bases:

>100_bases
GCATTCCAACCACCATTCAGCATTTGGGTCAAAAGCTGCAACGGCAATGCAACAAGAAGCAGCGCCTATGCGATACGAGA
CTCGCGAACCTGGGAAACGG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MKKEFELNYSLSVLKAAIEATVDGLLVTDRRGKVLCYNQLYVNMWPIPGELLAHARHQAILGYCAGQLRDPEQFLRSIEE
IYATLAPESFNVFEFRNGRVFERCAKVKTLEGSDIVLVWSFRDITERRQGESYKAQLAAIVESSNDAIIVKDLNGIITGW
NAAAEELFGYRSGEIIGSSILTLIPPDRLEEEDRIMNLVKSGKRTDHFETVRWGKGKKSIDVSVTISPVKDSAGNIIGAS
KIARDITQRKESQERIEYLAHYDLLTGLPNRALFTDRMRIAIENASRYAFRLALLFVDLDRFKLINDSLGHAIGDKLLKA
VAERMQSTVRQADTVSRLGGDEFVVLLGRIHTATEAARVAEKLIAVLSQPYQIEQHELLLTASVGISIYPDSGKDVNSLM
RNADVSMYSAKGQGRNRYQFYSEDLTSGADERLRLEYDLRSALARDEIFPVYQPQLELATGRVVGVEALMRWKHPERGLV
SPASFIPVAEDSGLILSLGEHILRESCLQARQWHEQQGFEGTIAVNVSAVQFRQNDFTDVVLRALADSGLSPECLELELT
ESVVMHGVESATQKMCFLESRGIKLAIDDFGTGYSSLSYLRQFAIDRLKIDRSFVRDLPQDTDAKAIIRATVAMGRSLGL
RVMAEGVETEGQAEYLRSVQCDESQGYLYARPMRPDDFEAWLKGRKPDFRGSRYQMAQS

Sequences:

>Translated_699_residues
MKKEFELNYSLSVLKAAIEATVDGLLVTDRRGKVLCYNQLYVNMWPIPGELLAHARHQAILGYCAGQLRDPEQFLRSIEE
IYATLAPESFNVFEFRNGRVFERCAKVKTLEGSDIVLVWSFRDITERRQGESYKAQLAAIVESSNDAIIVKDLNGIITGW
NAAAEELFGYRSGEIIGSSILTLIPPDRLEEEDRIMNLVKSGKRTDHFETVRWGKGKKSIDVSVTISPVKDSAGNIIGAS
KIARDITQRKESQERIEYLAHYDLLTGLPNRALFTDRMRIAIENASRYAFRLALLFVDLDRFKLINDSLGHAIGDKLLKA
VAERMQSTVRQADTVSRLGGDEFVVLLGRIHTATEAARVAEKLIAVLSQPYQIEQHELLLTASVGISIYPDSGKDVNSLM
RNADVSMYSAKGQGRNRYQFYSEDLTSGADERLRLEYDLRSALARDEIFPVYQPQLELATGRVVGVEALMRWKHPERGLV
SPASFIPVAEDSGLILSLGEHILRESCLQARQWHEQQGFEGTIAVNVSAVQFRQNDFTDVVLRALADSGLSPECLELELT
ESVVMHGVESATQKMCFLESRGIKLAIDDFGTGYSSLSYLRQFAIDRLKIDRSFVRDLPQDTDAKAIIRATVAMGRSLGL
RVMAEGVETEGQAEYLRSVQCDESQGYLYARPMRPDDFEAWLKGRKPDFRGSRYQMAQS
>Mature_699_residues
MKKEFELNYSLSVLKAAIEATVDGLLVTDRRGKVLCYNQLYVNMWPIPGELLAHARHQAILGYCAGQLRDPEQFLRSIEE
IYATLAPESFNVFEFRNGRVFERCAKVKTLEGSDIVLVWSFRDITERRQGESYKAQLAAIVESSNDAIIVKDLNGIITGW
NAAAEELFGYRSGEIIGSSILTLIPPDRLEEEDRIMNLVKSGKRTDHFETVRWGKGKKSIDVSVTISPVKDSAGNIIGAS
KIARDITQRKESQERIEYLAHYDLLTGLPNRALFTDRMRIAIENASRYAFRLALLFVDLDRFKLINDSLGHAIGDKLLKA
VAERMQSTVRQADTVSRLGGDEFVVLLGRIHTATEAARVAEKLIAVLSQPYQIEQHELLLTASVGISIYPDSGKDVNSLM
RNADVSMYSAKGQGRNRYQFYSEDLTSGADERLRLEYDLRSALARDEIFPVYQPQLELATGRVVGVEALMRWKHPERGLV
SPASFIPVAEDSGLILSLGEHILRESCLQARQWHEQQGFEGTIAVNVSAVQFRQNDFTDVVLRALADSGLSPECLELELT
ESVVMHGVESATQKMCFLESRGIKLAIDDFGTGYSSLSYLRQFAIDRLKIDRSFVRDLPQDTDAKAIIRATVAMGRSLGL
RVMAEGVETEGQAEYLRSVQCDESQGYLYARPMRPDDFEAWLKGRKPDFRGSRYQMAQS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=568, Percent_Identity=34.1549295774648, Blast_Score=305, Evalue=7e-84,
Organism=Escherichia coli, GI87081921, Length=580, Percent_Identity=30, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI226510982, Length=452, Percent_Identity=27.4336283185841, Blast_Score=186, Evalue=6e-48,
Organism=Escherichia coli, GI1788381, Length=586, Percent_Identity=25.4266211604096, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI1787055, Length=486, Percent_Identity=25.9259259259259, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI87081845, Length=237, Percent_Identity=37.9746835443038, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788502, Length=252, Percent_Identity=32.9365079365079, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI87081980, Length=259, Percent_Identity=35.1351351351351, Blast_Score=151, Evalue=2e-37,
Organism=Escherichia coli, GI1790496, Length=257, Percent_Identity=30.3501945525292, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1786507, Length=275, Percent_Identity=33.8181818181818, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87081743, Length=249, Percent_Identity=34.5381526104418, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=35.3591160220994, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788849, Length=435, Percent_Identity=26.2068965517241, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI87082096, Length=206, Percent_Identity=30.5825242718447, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=32.5842696629214, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=35.9756097560976, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=32.7272727272727, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI87082007, Length=231, Percent_Identity=31.6017316017316, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788956, Length=155, Percent_Identity=34.1935483870968, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=33.1288343558282, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=31.5151515151515, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI87081977, Length=167, Percent_Identity=31.1377245508982, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787410, Length=221, Percent_Identity=25.3393665158371, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788085, Length=165, Percent_Identity=27.8787878787879, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081974, Length=85, Percent_Identity=34.1176470588235, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 78480; Mature: 78480

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEFELNYSLSVLKAAIEATVDGLLVTDRRGKVLCYNQLYVNMWPIPGELLAHARHQAI
CCCCEECCCHHHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHH
LGYCAGQLRDPEQFLRSIEEIYATLAPESFNVFEFRNGRVFERCAKVKTLEGSDIVLVWS
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHEEECCCCEEEEEE
FRDITERRQGESYKAQLAAIVESSNDAIIVKDLNGIITGWNAAAEELFGYRSGEIIGSSI
CHHHHHHHCCCHHHHHHHHHEECCCCEEEEEECCCEEECCCHHHHHHHCCCCCCCCCCCH
LTLIPPDRLEEEDRIMNLVKSGKRTDHFETVRWGKGKKSIDVSVTISPVKDSAGNIIGAS
HEECCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEEEEEECCCCCCCCEEEHH
KIARDITQRKESQERIEYLAHYDLLTGLPNRALFTDRMRIAIENASRYAFRLALLFVDLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEECCHHHHHHHHHHHHHHH
RFKLINDSLGHAIGDKLLKAVAERMQSTVRQADTVSRLGGDEFVVLLGRIHTATEAARVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHH
EKLIAVLSQPYQIEQHELLLTASVGISIYPDSGKDVNSLMRNADVSMYSAKGQGRNRYQF
HHHHHHHCCCCEECCCEEEEEEECCEEEECCCCCHHHHHHHCCCCEEEECCCCCCCCCEE
YSEDLTSGADERLRLEYDLRSALARDEIFPVYQPQLELATGRVVGVEALMRWKHPERGLV
HHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCC
SPASFIPVAEDSGLILSLGEHILRESCLQARQWHEQQGFEGTIAVNVSAVQFRQNDFTDV
CCCCCCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHH
VLRALADSGLSPECLELELTESVVMHGVESATQKMCFLESRGIKLAIDDFGTGYSSLSYL
HHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
RQFAIDRLKIDRSFVRDLPQDTDAKAIIRATVAMGRSLGLRVMAEGVETEGQAEYLRSVQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHEECCCCCCCHHHHHHHCC
CDESQGYLYARPMRPDDFEAWLKGRKPDFRGSRYQMAQS
CCCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKEFELNYSLSVLKAAIEATVDGLLVTDRRGKVLCYNQLYVNMWPIPGELLAHARHQAI
CCCCEECCCHHHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHH
LGYCAGQLRDPEQFLRSIEEIYATLAPESFNVFEFRNGRVFERCAKVKTLEGSDIVLVWS
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHEEECCCCEEEEEE
FRDITERRQGESYKAQLAAIVESSNDAIIVKDLNGIITGWNAAAEELFGYRSGEIIGSSI
CHHHHHHHCCCHHHHHHHHHEECCCCEEEEEECCCEEECCCHHHHHHHCCCCCCCCCCCH
LTLIPPDRLEEEDRIMNLVKSGKRTDHFETVRWGKGKKSIDVSVTISPVKDSAGNIIGAS
HEECCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEEEEEECCCCCCCCEEEHH
KIARDITQRKESQERIEYLAHYDLLTGLPNRALFTDRMRIAIENASRYAFRLALLFVDLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEECCHHHHHHHHHHHHHHH
RFKLINDSLGHAIGDKLLKAVAERMQSTVRQADTVSRLGGDEFVVLLGRIHTATEAARVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHH
EKLIAVLSQPYQIEQHELLLTASVGISIYPDSGKDVNSLMRNADVSMYSAKGQGRNRYQF
HHHHHHHCCCCEECCCEEEEEEECCEEEECCCCCHHHHHHHCCCCEEEECCCCCCCCCEE
YSEDLTSGADERLRLEYDLRSALARDEIFPVYQPQLELATGRVVGVEALMRWKHPERGLV
HHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCC
SPASFIPVAEDSGLILSLGEHILRESCLQARQWHEQQGFEGTIAVNVSAVQFRQNDFTDV
CCCCCCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHH
VLRALADSGLSPECLELELTESVVMHGVESATQKMCFLESRGIKLAIDDFGTGYSSLSYL
HHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
RQFAIDRLKIDRSFVRDLPQDTDAKAIIRATVAMGRSLGLRVMAEGVETEGQAEYLRSVQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHEECCCCCCCHHHHHHHCC
CDESQGYLYARPMRPDDFEAWLKGRKPDFRGSRYQMAQS
CCCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]