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The map label for this gene is engD [H]

Identifier: 82701726

GI number: 82701726

Start: 676959

End: 678062

Strand: Direct

Name: engD [H]

Synonym: Nmul_A0592

Alternate gene names: 82701726

Gene position: 676959-678062 (Clockwise)

Preceding gene: 82701725

Following gene: 82701729

Centisome position: 21.26

GC content: 55.43

Gene sequence:

>1104_bases
ATGAGCCTGAAATGCGGTATTGTTGGCTTGCCCAACGTCGGAAAATCCACCCTCTTCAATGCCCTCACCAAGGCTGGCAT
CGCTGCCGAGAACTACCCCTTCTGCACCATCGAACCGAATGTGGGCATTGTCGAAGTTCCCGACTCTCGGCTGACTGAAC
TTGCTGCGATCGTCAAGCCGCAAAAGGTGCAGTCTGCAGTGGTTGAATTCGTCGATATTGCCGGTCTTGTCGCAGGGGCT
TCGAAAGGAGAGGGATTGGGCAACAAATTTCTTGCCACCATTCGTGAGACCGACGGCATCATCAATATGGTGCGCTGCTT
CAAGAATGACAACGTGGTGCACGTCTCCGGCAAAGTCGATCCCATCTCGGATATCGAAACCATCCAGACTGAACTGGCAC
TCGCCGATCTGGCCACCGTCGAAAAGGTGGTACAACGGGAAACCAAGCTTGCCAAGTCCGGTGACAAGGAAGCGGTCAAG
TTCGTCGCGCTGCTCGAAAAGGTAAGGGAGCATCTCGACCAGGGCAAGCCGGTAAGAAGTCTCGGGTTGGCTGAAGGACT
TGATAAGGAACAACAGGAACTGCTCAAGCCGCTATGCCTGCTCACTGCCAAACCTGCGATCTATGTGGCTAACGTGGACG
AAAAAGGATTCACCGGTAATCCGCTGCTGGCACGGGTGGAAGAATATGCGGCAGGCGAGGGCGCGCCTGTCGTTGCCATC
TGCGCCGCCCTCGAATCCGAAATTGCCGAGATGCCGGATGAGGACAAGCAGGTTTTTCTCGCCGACATGAATCTGGAAGA
ACCGGGGCTCAACCGCCTGGTGCGCGCCGCCTATCAACTGCTGGGGCTGCAGACCTACTTTACCGCTGGGGTGAAGGAAG
TGCGCGCCTGGACCATATCAAAAGGAGATACCGCGCCCCAAGCCGCTGCTGTCATTCATACCGATTTCGAAAAGGGCTTT
ATCCGCGCCGAGGTCATCAGCTATGACGACTTCGTTACCTGCAAAGGTGAGCAGGGTGCCAAGGAGGCAGGCAAGATGCG
GCTGGAGGGAAAGGAGTATGTCGTCAGAGATGGGGATGTGATGCATTTTCGGTTTAACGTCTAA

Upstream 100 bases:

>100_bases
CCGAAAACGGAGATTTAGCCTGCTGCGTGAAAATGACGGAACAACTTTCATACCCCTTTAACCATTACAGCCTGTCTTAA
ACGAGTAACCAAATCAAACC

Downstream 100 bases:

>100_bases
GCCTGAGTCCTTGTCTTATAGTGACGACCATGCTTTCCAAGCATGAGGCGGACAAATCTGGACACTCCATGATGACCTTG
GTTGTGACTGGCGTCACCAG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDSRLTELAAIVKPQKVQSAVVEFVDIAGLVAGA
SKGEGLGNKFLATIRETDGIINMVRCFKNDNVVHVSGKVDPISDIETIQTELALADLATVEKVVQRETKLAKSGDKEAVK
FVALLEKVREHLDQGKPVRSLGLAEGLDKEQQELLKPLCLLTAKPAIYVANVDEKGFTGNPLLARVEEYAAGEGAPVVAI
CAALESEIAEMPDEDKQVFLADMNLEEPGLNRLVRAAYQLLGLQTYFTAGVKEVRAWTISKGDTAPQAAAVIHTDFEKGF
IRAEVISYDDFVTCKGEQGAKEAGKMRLEGKEYVVRDGDVMHFRFNV

Sequences:

>Translated_367_residues
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDSRLTELAAIVKPQKVQSAVVEFVDIAGLVAGA
SKGEGLGNKFLATIRETDGIINMVRCFKNDNVVHVSGKVDPISDIETIQTELALADLATVEKVVQRETKLAKSGDKEAVK
FVALLEKVREHLDQGKPVRSLGLAEGLDKEQQELLKPLCLLTAKPAIYVANVDEKGFTGNPLLARVEEYAAGEGAPVVAI
CAALESEIAEMPDEDKQVFLADMNLEEPGLNRLVRAAYQLLGLQTYFTAGVKEVRAWTISKGDTAPQAAAVIHTDFEKGF
IRAEVISYDDFVTCKGEQGAKEAGKMRLEGKEYVVRDGDVMHFRFNV
>Mature_366_residues
SLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDSRLTELAAIVKPQKVQSAVVEFVDIAGLVAGAS
KGEGLGNKFLATIRETDGIINMVRCFKNDNVVHVSGKVDPISDIETIQTELALADLATVEKVVQRETKLAKSGDKEAVKF
VALLEKVREHLDQGKPVRSLGLAEGLDKEQQELLKPLCLLTAKPAIYVANVDEKGFTGNPLLARVEEYAAGEGAPVVAIC
AALESEIAEMPDEDKQVFLADMNLEEPGLNRLVRAAYQLLGLQTYFTAGVKEVRAWTISKGDTAPQAAAVIHTDFEKGFI
RAEVISYDDFVTCKGEQGAKEAGKMRLEGKEYVVRDGDVMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=372, Percent_Identity=44.6236559139785, Blast_Score=309, Evalue=3e-84,
Organism=Homo sapiens, GI58761502, Length=221, Percent_Identity=39.8190045248869, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI1787454, Length=367, Percent_Identity=63.4877384196185, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI1789574, Length=136, Percent_Identity=30.8823529411765, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=370, Percent_Identity=41.0810810810811, Blast_Score=281, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=38.5026737967914, Blast_Score=242, Evalue=6e-65,
Organism=Saccharomyces cerevisiae, GI6321773, Length=384, Percent_Identity=33.8541666666667, Blast_Score=210, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321649, Length=143, Percent_Identity=39.8601398601399, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640873, Length=371, Percent_Identity=41.7789757412399, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24640877, Length=371, Percent_Identity=41.7789757412399, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24640875, Length=371, Percent_Identity=41.7789757412399, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24640879, Length=329, Percent_Identity=39.209726443769, Blast_Score=221, Evalue=9e-58,
Organism=Drosophila melanogaster, GI24585318, Length=140, Percent_Identity=33.5714285714286, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39677; Mature: 39546

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDSRLTELAAIVKP
CCCEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCC
QKVQSAVVEFVDIAGLVAGASKGEGLGNKFLATIRETDGIINMVRCFKNDNVVHVSGKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PISDIETIQTELALADLATVEKVVQRETKLAKSGDKEAVKFVALLEKVREHLDQGKPVRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
LGLAEGLDKEQQELLKPLCLLTAKPAIYVANVDEKGFTGNPLLARVEEYAAGEGAPVVAI
HHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHH
CAALESEIAEMPDEDKQVFLADMNLEEPGLNRLVRAAYQLLGLQTYFTAGVKEVRAWTIS
HHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
KGDTAPQAAAVIHTDFEKGFIRAEVISYDDFVTCKGEQGAKEAGKMRLEGKEYVVRDGDV
CCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEECCCCCCHHHCCEEECCCEEEEECCCE
MHFRFNV
EEEEECC
>Mature Secondary Structure 
SLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDSRLTELAAIVKP
CCEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCC
QKVQSAVVEFVDIAGLVAGASKGEGLGNKFLATIRETDGIINMVRCFKNDNVVHVSGKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PISDIETIQTELALADLATVEKVVQRETKLAKSGDKEAVKFVALLEKVREHLDQGKPVRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
LGLAEGLDKEQQELLKPLCLLTAKPAIYVANVDEKGFTGNPLLARVEEYAAGEGAPVVAI
HHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHH
CAALESEIAEMPDEDKQVFLADMNLEEPGLNRLVRAAYQLLGLQTYFTAGVKEVRAWTIS
HHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
KGDTAPQAAAVIHTDFEKGFIRAEVISYDDFVTCKGEQGAKEAGKMRLEGKEYVVRDGDV
CCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEECCCCCCHHHCCEEECCCEEEEECCCE
MHFRFNV
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA