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The map label for this gene is thrB

Identifier: 82701699

GI number: 82701699

Start: 651780

End: 652730

Strand: Reverse

Name: thrB

Synonym: Nmul_A0565

Alternate gene names: 82701699

Gene position: 652730-651780 (Counterclockwise)

Preceding gene: 82701700

Following gene: 82701698

Centisome position: 20.5

GC content: 54.89

Gene sequence:

>951_bases
ATGTCTGTCTTCACCATAGTTACCCATGAGCAGCTTTCCGCATGGCTGAGAAATTATTCCATCGGCAAATTGGTCAATCT
GCAGGGTATTTCTTCCGGCATTGAAAATACGAATTATTTTGTCACTACCAGCCACGGCAAATATGTTCTGACACTATTTG
AAAAACTGACTTCGGCGGAACTACCCTACTATTTGAATCTGATGGCCTACCTGGCGCGCCACGGCCTTCCCTGCCCCAGC
CCAGTGGCGGATCTCGCCAATAAATTCCTGGGAGAGCTCAATGGCAAGCCGGCGAGCATCGTCACCTGCCTTCCCGGAAA
GTCGCAGGAATCTCCCACGGCCACCCATTGCGCCGAGGTTGGCGAACTCCTGGCCAACATGCATTTATCCGGCTTATCCT
ATCCGGAAAAAATGGAGAATTTGCGAGGGCCCAGATGGTGGAAAGCTGCGGCGCAGGAAGTCATGCCGTTTCTTTCGGAG
GATGAGGCTGCGATTCTCGGGGAGGAATTACGCTTTCAATCATCGCATAGAACGGAAAGCCTTCCCCGGGGCGTGATCCA
TGCCGACCTGTTTCGTGACAATGTCCTTTTCAAGGATGGCGCAATGGGCGGAGTGATCGATTTCTACTTTGCCTGCAACG
ATGTGCTGCTGTACGACCTGGCGATTACCGCGAACGACTGGTGTCTCAACGAAAATGCGGAATTGGATCCGGAGCGGACT
TTATCGCTGCTCGAAGCCTATCACCGCACCCGGCCGCTGCTGGAGATTGAGCGTGACGCCTGGCCAGTGATGCTGCGCGC
CGGCGCGCTGCGCTTCTGGCTTTCACGCCTGCAGGACTATCACCTGCCGCGCGCCGGAGAACTTACGCACGTGAAGGATC
CTGCTCACTTCATGCGTATACTGCAAAGCCATGCAGCAGCACGCTCGAAGCTTGCCGAGGTGTGGATCTGA

Upstream 100 bases:

>100_bases
TCAGCGTATTCGCCCTCCCATGTGGGTGATACGCGAGTTCTGATTTTCCAGGACAGCCATTGCGCCTGATTAAACTGCTT
CTGCCTTACTTTCCCGCTCC

Downstream 100 bases:

>100_bases
GCGCCAGTTGAACAGCAGGCGGGATGGAAGACGTTTATCGGAGAAAAAACAAGATGAATATCAGGCAGGTAGACGGGAGA
AGGGGATGGGAATGGATAGC

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSVFTIVTHEQLSAWLRNYSIGKLVNLQGISSGIENTNYFVTTSHGKYVLTLFEKLTSAELPYYLNLMAYLARHGLPCPS
PVADLANKFLGELNGKPASIVTCLPGKSQESPTATHCAEVGELLANMHLSGLSYPEKMENLRGPRWWKAAAQEVMPFLSE
DEAAILGEELRFQSSHRTESLPRGVIHADLFRDNVLFKDGAMGGVIDFYFACNDVLLYDLAITANDWCLNENAELDPERT
LSLLEAYHRTRPLLEIERDAWPVMLRAGALRFWLSRLQDYHLPRAGELTHVKDPAHFMRILQSHAAARSKLAEVWI

Sequences:

>Translated_316_residues
MSVFTIVTHEQLSAWLRNYSIGKLVNLQGISSGIENTNYFVTTSHGKYVLTLFEKLTSAELPYYLNLMAYLARHGLPCPS
PVADLANKFLGELNGKPASIVTCLPGKSQESPTATHCAEVGELLANMHLSGLSYPEKMENLRGPRWWKAAAQEVMPFLSE
DEAAILGEELRFQSSHRTESLPRGVIHADLFRDNVLFKDGAMGGVIDFYFACNDVLLYDLAITANDWCLNENAELDPERT
LSLLEAYHRTRPLLEIERDAWPVMLRAGALRFWLSRLQDYHLPRAGELTHVKDPAHFMRILQSHAAARSKLAEVWI
>Mature_315_residues
SVFTIVTHEQLSAWLRNYSIGKLVNLQGISSGIENTNYFVTTSHGKYVLTLFEKLTSAELPYYLNLMAYLARHGLPCPSP
VADLANKFLGELNGKPASIVTCLPGKSQESPTATHCAEVGELLANMHLSGLSYPEKMENLRGPRWWKAAAQEVMPFLSED
EAAILGEELRFQSSHRTESLPRGVIHADLFRDNVLFKDGAMGGVIDFYFACNDVLLYDLAITANDWCLNENAELDPERTL
SLLEAYHRTRPLLEIERDAWPVMLRAGALRFWLSRLQDYHLPRAGELTHVKDPAHFMRILQSHAAARSKLAEVWI

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_NITMU (Q2YBJ8)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411265.1
- ProteinModelPortal:   Q2YBJ8
- SMR:   Q2YBJ8
- STRING:   Q2YBJ8
- GeneID:   3784785
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0565
- eggNOG:   COG2334
- HOGENOM:   HBG309377
- OMA:   ADLFRDN
- ProtClustDB:   PRK05231
- BioCyc:   NMUL323848:NMUL_A0565-MONOMER
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 35570; Mature: 35439

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFTIVTHEQLSAWLRNYSIGKLVNLQGISSGIENTNYFVTTSHGKYVLTLFEKLTSAE
CCEEEEEEHHHHHHHHHCCCCCCEEEHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCC
LPYYLNLMAYLARHGLPCPSPVADLANKFLGELNGKPASIVTCLPGKSQESPTATHCAEV
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHH
GELLANMHLSGLSYPEKMENLRGPRWWKAAAQEVMPFLSEDEAAILGEELRFQSSHRTES
HHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHH
LPRGVIHADLFRDNVLFKDGAMGGVIDFYFACNDVLLYDLAITANDWCLNENAELDPERT
CCCCHHHHHHHHCCEEEECCCCCCHHHHHHHHCCEEEEEEEEECCCEECCCCCCCCHHHH
LSLLEAYHRTRPLLEIERDAWPVMLRAGALRFWLSRLQDYHLPRAGELTHVKDPAHFMRI
HHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LQSHAAARSKLAEVWI
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVFTIVTHEQLSAWLRNYSIGKLVNLQGISSGIENTNYFVTTSHGKYVLTLFEKLTSAE
CEEEEEEHHHHHHHHHCCCCCCEEEHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCC
LPYYLNLMAYLARHGLPCPSPVADLANKFLGELNGKPASIVTCLPGKSQESPTATHCAEV
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHH
GELLANMHLSGLSYPEKMENLRGPRWWKAAAQEVMPFLSEDEAAILGEELRFQSSHRTES
HHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHH
LPRGVIHADLFRDNVLFKDGAMGGVIDFYFACNDVLLYDLAITANDWCLNENAELDPERT
CCCCHHHHHHHHCCEEEECCCCCCHHHHHHHHCCEEEEEEEEECCCEECCCCCCCCHHHH
LSLLEAYHRTRPLLEIERDAWPVMLRAGALRFWLSRLQDYHLPRAGELTHVKDPAHFMRI
HHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LQSHAAARSKLAEVWI
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA