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The map label for this gene is anmK

Identifier: 82701689

GI number: 82701689

Start: 642089

End: 643189

Strand: Direct

Name: anmK

Synonym: Nmul_A0555

Alternate gene names: 82701689

Gene position: 642089-643189 (Clockwise)

Preceding gene: 82701688

Following gene: 82701696

Centisome position: 20.16

GC content: 59.67

Gene sequence:

>1101_bases
TTGAAGGCGGCGTACTATATCGGCATCATGTCGGGCACCAGTCTGGATGGGATCGACGCAGTGCTTGCCGACTTTGAAGC
CCCCCGGCCGGTGTTGCTGGACAACTTCTATCTGCCATACCCGGAGAAGCTCCGCGAACAGCTCAAGGCACTCCATTTTC
CGGCTCATGGCGAGCTGCACCGCGCCGCGACGCTTGGTAATCAGCTCGCTCGTCATTATGCTGAAGCAGTGGGGGGCTTG
CTCCGCAAAAGCGGGGTTGCGCCGCCCGAAGTCGCTGCCATCGGATGCCATGGGCAAACCATCCGTCATTGTCCCCAGGC
AGAAGCGGGTTACACCATCCAGTTATGCAATTCTCCGTTACTGGTAGAGCTCACCGGAATCAGGGTTGTTTCCGATTTCA
GGAGTCGCGATATCGCTGCGGGAGGACAGGGCGCCCCCCTGGTGCCGGCATTTCATCAGGCTCTGTTCGCGGACCCTCAT
GTTCATCGCGTGATCGTCAATATCGGGGGGATCAGCAATCTTACCGATCTGCCGCGGAATGGAAGCGTGACAGGATTCGA
TTGCGGTCCGGGCAATGCCATGATGGACGAGTGGTGCGCGCGCCATACCGGGCAAGCATATGATGAGGAGGGAAGGTGGG
CGGCAACCGGAAAAACGCTTTCCGTGCTGCTGGAAAAGCTGCTGGCATTGCCATTTTTTTCCCTTCCCCCGCCCAAAAGC
GTCAGCAGGGAATTATTCAGTACAACGTGGCTGGAAGGCTACCTGAAGGGGGATGAGAGCCCGGCCGATGTCCAGGCCAC
CCTGCTGGAGCTGACCGTCGCCGGAATTGCCCGCTGTATACTCGGTTACTGCGGGGATGCAACCGAAATTTATGTATGCG
GCGGGGGGGCACGGAACAGCTACCTCATCGCCTCCCTTCAGGAGGCCTTATCCGGCAGGAAAGTCGGATTGACAGACAGC
CTGGGCGTGGACGCTGACTGGCTGGAAGCTTTCGCCTTTGCCTGGCTTGCGCGGCAACTCATCCAGGGCATCCCGGGTAA
TATTCCCTCGGTCACTGGCGCGAAGGGCCCCCGGCTTCTCGGGGCCATCTACCCTGCCTAG

Upstream 100 bases:

>100_bases
GCGAGGCTCGATATGCTGCACGGCACCAATCTCGCATTGCTGGATTAACGGCGGTGGCCGAACGGGTCGACTGGATAAAA
GTCCCGTCAACGGGAGAGAT

Downstream 100 bases:

>100_bases
GGCCTATATCCCTTCAGGACTTTCTTTTACCCCGAAAGAAGGGACGGAAGTGGATGTGGGGATCCGTGAATTAACCCCCA
GGGGTTATTAAACGGAGAAT

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKAAYYIGIMSGTSLDGIDAVLADFEAPRPVLLDNFYLPYPEKLREQLKALHFPAHGELHRAATLGNQLARHYAEAVGGL
LRKSGVAPPEVAAIGCHGQTIRHCPQAEAGYTIQLCNSPLLVELTGIRVVSDFRSRDIAAGGQGAPLVPAFHQALFADPH
VHRVIVNIGGISNLTDLPRNGSVTGFDCGPGNAMMDEWCARHTGQAYDEEGRWAATGKTLSVLLEKLLALPFFSLPPPKS
VSRELFSTTWLEGYLKGDESPADVQATLLELTVAGIARCILGYCGDATEIYVCGGGARNSYLIASLQEALSGRKVGLTDS
LGVDADWLEAFAFAWLARQLIQGIPGNIPSVTGAKGPRLLGAIYPA

Sequences:

>Translated_366_residues
MKAAYYIGIMSGTSLDGIDAVLADFEAPRPVLLDNFYLPYPEKLREQLKALHFPAHGELHRAATLGNQLARHYAEAVGGL
LRKSGVAPPEVAAIGCHGQTIRHCPQAEAGYTIQLCNSPLLVELTGIRVVSDFRSRDIAAGGQGAPLVPAFHQALFADPH
VHRVIVNIGGISNLTDLPRNGSVTGFDCGPGNAMMDEWCARHTGQAYDEEGRWAATGKTLSVLLEKLLALPFFSLPPPKS
VSRELFSTTWLEGYLKGDESPADVQATLLELTVAGIARCILGYCGDATEIYVCGGGARNSYLIASLQEALSGRKVGLTDS
LGVDADWLEAFAFAWLARQLIQGIPGNIPSVTGAKGPRLLGAIYPA
>Mature_366_residues
MKAAYYIGIMSGTSLDGIDAVLADFEAPRPVLLDNFYLPYPEKLREQLKALHFPAHGELHRAATLGNQLARHYAEAVGGL
LRKSGVAPPEVAAIGCHGQTIRHCPQAEAGYTIQLCNSPLLVELTGIRVVSDFRSRDIAAGGQGAPLVPAFHQALFADPH
VHRVIVNIGGISNLTDLPRNGSVTGFDCGPGNAMMDEWCARHTGQAYDEEGRWAATGKTLSVLLEKLLALPFFSLPPPKS
VSRELFSTTWLEGYLKGDESPADVQATLLELTVAGIARCILGYCGDATEIYVCGGGARNSYLIASLQEALSGRKVGLTDS
LGVDADWLEAFAFAWLARQLIQGIPGNIPSVTGAKGPRLLGAIYPA

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=368, Percent_Identity=46.195652173913, Blast_Score=312, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_NITMU (Q2YBK8)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411255.1
- ProteinModelPortal:   Q2YBK8
- SMR:   Q2YBK8
- STRING:   Q2YBK8
- GeneID:   3784738
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0555
- eggNOG:   COG2377
- HOGENOM:   HBG324434
- OMA:   GSHGQTV
- PhylomeDB:   Q2YBK8
- ProtClustDB:   PRK09585
- BioCyc:   NMUL323848:NMUL_A0555-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 39030; Mature: 39030

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAYYIGIMSGTSLDGIDAVLADFEAPRPVLLDNFYLPYPEKLREQLKALHFPAHGELH
CCCEEEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCHH
RAATLGNQLARHYAEAVGGLLRKSGVAPPEVAAIGCHGQTIRHCPQAEAGYTIQLCNSPL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHCCCCCCCCCEEEECCCCE
LVELTGIRVVSDFRSRDIAAGGQGAPLVPAFHQALFADPHVHRVIVNIGGISNLTDLPRN
EEEEECHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHCCCCC
GSVTGFDCGPGNAMMDEWCARHTGQAYDEEGRWAATGKTLSVLLEKLLALPFFSLPPPKS
CCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCHH
VSRELFSTTWLEGYLKGDESPADVQATLLELTVAGIARCILGYCGDATEIYVCGGGARNS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
YLIASLQEALSGRKVGLTDSLGVDADWLEAFAFAWLARQLIQGIPGNIPSVTGAKGPRLL
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEH
GAIYPA
EECCCC
>Mature Secondary Structure
MKAAYYIGIMSGTSLDGIDAVLADFEAPRPVLLDNFYLPYPEKLREQLKALHFPAHGELH
CCCEEEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCHH
RAATLGNQLARHYAEAVGGLLRKSGVAPPEVAAIGCHGQTIRHCPQAEAGYTIQLCNSPL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHCCCCCCCCCEEEECCCCE
LVELTGIRVVSDFRSRDIAAGGQGAPLVPAFHQALFADPHVHRVIVNIGGISNLTDLPRN
EEEEECHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHCCCCC
GSVTGFDCGPGNAMMDEWCARHTGQAYDEEGRWAATGKTLSVLLEKLLALPFFSLPPPKS
CCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCHH
VSRELFSTTWLEGYLKGDESPADVQATLLELTVAGIARCILGYCGDATEIYVCGGGARNS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
YLIASLQEALSGRKVGLTDSLGVDADWLEAFAFAWLARQLIQGIPGNIPSVTGAKGPRLL
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEH
GAIYPA
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA