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The map label for this gene is glmM

Identifier: 82701619

GI number: 82701619

Start: 543137

End: 544528

Strand: Direct

Name: glmM

Synonym: Nmul_A0485

Alternate gene names: 82701619

Gene position: 543137-544528 (Clockwise)

Preceding gene: 82701618

Following gene: 82701620

Centisome position: 17.06

GC content: 55.46

Gene sequence:

>1392_bases
ATGACAAGAAAATATTTTGGAACTGACGGCATACGCGGACGCGTAGGTGAAGCGCCTATCACGCCCGAATTCGTGATACA
TCTGGGTTATTCTGCGGGCAAGGTTCTGACCTCCTCGGATTGGCATCTTTCAAAAGGAGAGCGCCCGGCAGTATTGATCG
GCAAGGATACACGCATATCAGGCTATATGCTGGAATCAGCCTTGCAGGCGGGGCTTTCCGCAGCCGGAGTGGATGTTCTG
CTTTCGGGGCCTATGCCCACTCCTGCGGTTGCCTATCTCACCCGGGCCCTGCGTTTGCAGGCGGGCATCGTCATTTCGGC
TTCCCACAATCCTTTCGAGGATAACGGCATCAAGTTTTTTTCTGCCCTCGGCGCCAAATTACCCGATGCGACCGAACAGG
AGATTGAAGCGGGATTGAATGCGCCTCTCAAGGCAATGCCGTCGGCGCAGCTCGGAAAAGCGCGGCGCGTTAATGACGCC
AGAGGACGCTATATCGAGTTCTGCAAAAGCACTTTTCCAAATCACCTCGATCTGCGGGGACTGCGGGTCGTGGTCGATTG
CGCCCATGGCGCCACTTATCAGATTGCCGGTCCCGTATTGCACGAATTGGGCGCCGAAGTAGTTGCGATTGGAATCCATC
CCGATGGTCTCAATATCAATCACGAGTGTGGGGCAACGCATGGAGCGGCCCTGCAGGAAGCTGTCCGGCACCATCGGGCA
GATATCGGAGTGGCATTGGATGGGGATGGTGATCGCGTAATCATGACCGATGGCGAGGGCATGCTTTACGACGGCGACCA
GTTGATCTACCTCGTCGCGAAACATCGAAAACAAAACGGGCTGCTCAAGGGGGGGGTGGCGGGGACGCTCATGACGAATC
TGGCGATTGAAAACGGGTTAAAGAAACTGGATATTCCTTTTGCGCGCGCGAATGTCGGCGATCGCTATGTGCTGGAACTG
CTGCAGATAAAAAACTGGCAGCTGGGCGGCGAAGGTTCCGGCCATATTATCTGCCTCGACAAACATACTACCGGTGACGG
AATCATTTCGGCACTACAGGTACTCTACGCGATGCGTGATTCCGGCAAGACCTTGACCGAGCTCGCATCAGACGTGACGC
TCTATCCGCAACAACTCATCAATGTCAGGGTACCCAAGGGATTTGATGCGCACAACAGTCTTGCCATCAAAACCGCTCAA
GCAGAGGCCGAACGCGATCTCGATACTACGGGCCGGGTGCTTCTGCGTGCTTCGGGTACGGAACCCTTGATAAGAGTAAT
GGTAGAGGGCGAGTCCGGGCAGAAAGTCAAGCACTGGGCGGAGAAAATAGCGGAAGTTGTGCGAAATGCGGCGGCAGGCG
AGAGATCGGTTGAAAAGGCGCTGCCGAACTGA

Upstream 100 bases:

>100_bases
ACGACCGGGGCTCTGCACGGGAGAATGCATCATCGCTCACTTCACGGTGGAAACCCTCAGTTGAATTCAATTCATTTCGA
TAAACAATGGTTTTCTTCCA

Downstream 100 bases:

>100_bases
ATCAAAGGACATCTTGCTCCCTCTTCCCCCCGCCAAAGTTTTTGTCTGCCAGTTCTTTTTGGGAAAACTGATTCATGGAG
GAATACACCTTATATGCTCT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTRKYFGTDGIRGRVGEAPITPEFVIHLGYSAGKVLTSSDWHLSKGERPAVLIGKDTRISGYMLESALQAGLSAAGVDVL
LSGPMPTPAVAYLTRALRLQAGIVISASHNPFEDNGIKFFSALGAKLPDATEQEIEAGLNAPLKAMPSAQLGKARRVNDA
RGRYIEFCKSTFPNHLDLRGLRVVVDCAHGATYQIAGPVLHELGAEVVAIGIHPDGLNINHECGATHGAALQEAVRHHRA
DIGVALDGDGDRVIMTDGEGMLYDGDQLIYLVAKHRKQNGLLKGGVAGTLMTNLAIENGLKKLDIPFARANVGDRYVLEL
LQIKNWQLGGEGSGHIICLDKHTTGDGIISALQVLYAMRDSGKTLTELASDVTLYPQQLINVRVPKGFDAHNSLAIKTAQ
AEAERDLDTTGRVLLRASGTEPLIRVMVEGESGQKVKHWAEKIAEVVRNAAAGERSVEKALPN

Sequences:

>Translated_463_residues
MTRKYFGTDGIRGRVGEAPITPEFVIHLGYSAGKVLTSSDWHLSKGERPAVLIGKDTRISGYMLESALQAGLSAAGVDVL
LSGPMPTPAVAYLTRALRLQAGIVISASHNPFEDNGIKFFSALGAKLPDATEQEIEAGLNAPLKAMPSAQLGKARRVNDA
RGRYIEFCKSTFPNHLDLRGLRVVVDCAHGATYQIAGPVLHELGAEVVAIGIHPDGLNINHECGATHGAALQEAVRHHRA
DIGVALDGDGDRVIMTDGEGMLYDGDQLIYLVAKHRKQNGLLKGGVAGTLMTNLAIENGLKKLDIPFARANVGDRYVLEL
LQIKNWQLGGEGSGHIICLDKHTTGDGIISALQVLYAMRDSGKTLTELASDVTLYPQQLINVRVPKGFDAHNSLAIKTAQ
AEAERDLDTTGRVLLRASGTEPLIRVMVEGESGQKVKHWAEKIAEVVRNAAAGERSVEKALPN
>Mature_462_residues
TRKYFGTDGIRGRVGEAPITPEFVIHLGYSAGKVLTSSDWHLSKGERPAVLIGKDTRISGYMLESALQAGLSAAGVDVLL
SGPMPTPAVAYLTRALRLQAGIVISASHNPFEDNGIKFFSALGAKLPDATEQEIEAGLNAPLKAMPSAQLGKARRVNDAR
GRYIEFCKSTFPNHLDLRGLRVVVDCAHGATYQIAGPVLHELGAEVVAIGIHPDGLNINHECGATHGAALQEAVRHHRAD
IGVALDGDGDRVIMTDGEGMLYDGDQLIYLVAKHRKQNGLLKGGVAGTLMTNLAIENGLKKLDIPFARANVGDRYVLELL
QIKNWQLGGEGSGHIICLDKHTTGDGIISALQVLYAMRDSGKTLTELASDVTLYPQQLINVRVPKGFDAHNSLAIKTAQA
EAERDLDTTGRVLLRASGTEPLIRVMVEGESGQKVKHWAEKIAEVVRNAAAGERSVEKALPN

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=448, Percent_Identity=60.0446428571429, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1788361, Length=462, Percent_Identity=26.6233766233766, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_NITMU (Q2YBS8)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411185.1
- ProteinModelPortal:   Q2YBS8
- SMR:   Q2YBS8
- STRING:   Q2YBS8
- GeneID:   3784902
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0485
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- PhylomeDB:   Q2YBS8
- ProtClustDB:   PRK10887
- BioCyc:   NMUL323848:NMUL_A0485-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49594; Mature: 49463

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 108-108

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKYFGTDGIRGRVGEAPITPEFVIHLGYSAGKVLTSSDWHLSKGERPAVLIGKDTRIS
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCEEEEECCCCCH
GYMLESALQAGLSAAGVDVLLSGPMPTPAVAYLTRALRLQAGIVISASHNPFEDNGIKFF
HHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHH
SALGAKLPDATEQEIEAGLNAPLKAMPSAQLGKARRVNDARGRYIEFCKSTFPNHLDLRG
HHHCCCCCCCCHHHHHHCCCCCHHHCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
LRVVVDCAHGATYQIAGPVLHELGAEVVAIGIHPDGLNINHECGATHGAALQEAVRHHRA
EEEEEEECCCCEEEECHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHC
DIGVALDGDGDRVIMTDGEGMLYDGDQLIYLVAKHRKQNGLLKGGVAGTLMTNLAIENGL
CEEEEEECCCCEEEEECCCEEEECCCEEEEEEEHHHCCCCCEECCHHHHHHHHHHHHCCC
KKLDIPFARANVGDRYVLELLQIKNWQLGGEGSGHIICLDKHTTGDGIISALQVLYAMRD
HHCCCCHHHCCCCHHHHHHHHHHCCEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHC
SGKTLTELASDVTLYPQQLINVRVPKGFDAHNSLAIKTAQAEAERDLDTTGRVLLRASGT
CCCHHHHHHHHHHHCCHHHHEEECCCCCCCCCCEEEEEEHHHHHCCCCCCCEEEEEECCC
EPLIRVMVEGESGQKVKHWAEKIAEVVRNAAAGERSVEKALPN
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure 
TRKYFGTDGIRGRVGEAPITPEFVIHLGYSAGKVLTSSDWHLSKGERPAVLIGKDTRIS
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCEEEEECCCCCH
GYMLESALQAGLSAAGVDVLLSGPMPTPAVAYLTRALRLQAGIVISASHNPFEDNGIKFF
HHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHH
SALGAKLPDATEQEIEAGLNAPLKAMPSAQLGKARRVNDARGRYIEFCKSTFPNHLDLRG
HHHCCCCCCCCHHHHHHCCCCCHHHCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
LRVVVDCAHGATYQIAGPVLHELGAEVVAIGIHPDGLNINHECGATHGAALQEAVRHHRA
EEEEEEECCCCEEEECHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHC
DIGVALDGDGDRVIMTDGEGMLYDGDQLIYLVAKHRKQNGLLKGGVAGTLMTNLAIENGL
CEEEEEECCCCEEEEECCCEEEECCCEEEEEEEHHHCCCCCEECCHHHHHHHHHHHHCCC
KKLDIPFARANVGDRYVLELLQIKNWQLGGEGSGHIICLDKHTTGDGIISALQVLYAMRD
HHCCCCHHHCCCCHHHHHHHHHHCCEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHC
SGKTLTELASDVTLYPQQLINVRVPKGFDAHNSLAIKTAQAEAERDLDTTGRVLLRASGT
CCCHHHHHHHHHHHCCHHHHEEECCCCCCCCCCEEEEEEHHHHHCCCCCCCEEEEEECCC
EPLIRVMVEGESGQKVKHWAEKIAEVVRNAAAGERSVEKALPN
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA