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The map label for this gene is cah [H]

Identifier: 82701595

GI number: 82701595

Start: 512247

End: 513188

Strand: Reverse

Name: cah [H]

Synonym: Nmul_A0461

Alternate gene names: 82701595

Gene position: 513188-512247 (Counterclockwise)

Preceding gene: 82701596

Following gene: 82701594

Centisome position: 16.12

GC content: 52.44

Gene sequence:

>942_bases
ATGAATGAAACATCTCGATCCCTGAGGGTGGCCGTCCTTGCCGCGGTCCTTTTCTTGCTGGGCTTCAATACCGCATATGC
GAGTACGCTGGCGAGCAATCTGGAATTGATGGAAGCACAAAGTCCGATCGATATTCGCTCGAATAGCACCTATTACGGAA
ATTTGCCCAAGTTGAACTTCAACCTCAATTCCGATACCGCGCTTACCGTGATCAATAACGGCTCCCCTGATCACGAAAGT
ACTATCAGGGCTAATGTCAGTCCCGGCGGAGGAACCTTGATGTTGTCAGGACATCAATGGAACCTTGCTCAATTCCACTT
TCACACCCCCTCGGAACATTTGATAAACGGTCGAGCCAGTCCCATGGAAATGCACCTCGTCTTCAGCGATGCTGCGAACA
ATCTACTCGTGGTCGGCCGGGATATCGAGCAAGGTCTCTTCAAGAACCAGGCACTCGCTCCCATTTTCTCCGATTTGCCG
AAAACTACTGAGGAAACACTGAATATCGAGCACTTCAACCTGAACAATCTTCTGCCGGATTATCTCGGTTCTTTCCGCTA
CTCCGGTTCTCTGACGACGCCGCCTTTTACAGAAGGAGTAAGCTGGGTTGAACTGGCTTCTCCGCTATATCTATCCGGGA
GCCAGATCAATGCCTTCAAGTCCCTGTTTCCGGAAGGCAATTCGCGCGAGATTCAGGATTTGAACGGTCGCATCGTGCTT
ACCGACGTGCCGGGCTTCGTCAGCATCCATGATGACTCCGATCCCAATCTCCTGGGCACACTGATCCCTGGCCTGGAAGC
AAGCGTTTCTGTCACGGCCGACTTATCCAAACTCGCGACGAGCGTTCCCGAACCGTCATCCTATGGCATGCTCCTCGCCG
GGCTCGCGGTAATCAGTTTTATTGGCCTCAAGCGTGGGTCAAGACTCGCTGGAGCAACCTGA

Upstream 100 bases:

>100_bases
CCGTCTGACGAGCGCTGGAACCGATCATTCGGAATTTCTCAAGCTTTTAGAATTTTCATCCTATAAACCCTATGAACATC
TATTTTCGCGAGGTCATTTT

Downstream 100 bases:

>100_bases
ATCGCATTTCAGGTCCCGTGTTTCCGGTCGGTTCCGGCAATGTAGCGCCTGTTTTCCGGCCTCCCTCCAAACCGCAAACT
GGAAGAGCATTAGGGACCAT

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MNETSRSLRVAVLAAVLFLLGFNTAYASTLASNLELMEAQSPIDIRSNSTYYGNLPKLNFNLNSDTALTVINNGSPDHES
TIRANVSPGGGTLMLSGHQWNLAQFHFHTPSEHLINGRASPMEMHLVFSDAANNLLVVGRDIEQGLFKNQALAPIFSDLP
KTTEETLNIEHFNLNNLLPDYLGSFRYSGSLTTPPFTEGVSWVELASPLYLSGSQINAFKSLFPEGNSREIQDLNGRIVL
TDVPGFVSIHDDSDPNLLGTLIPGLEASVSVTADLSKLATSVPEPSSYGMLLAGLAVISFIGLKRGSRLAGAT

Sequences:

>Translated_313_residues
MNETSRSLRVAVLAAVLFLLGFNTAYASTLASNLELMEAQSPIDIRSNSTYYGNLPKLNFNLNSDTALTVINNGSPDHES
TIRANVSPGGGTLMLSGHQWNLAQFHFHTPSEHLINGRASPMEMHLVFSDAANNLLVVGRDIEQGLFKNQALAPIFSDLP
KTTEETLNIEHFNLNNLLPDYLGSFRYSGSLTTPPFTEGVSWVELASPLYLSGSQINAFKSLFPEGNSREIQDLNGRIVL
TDVPGFVSIHDDSDPNLLGTLIPGLEASVSVTADLSKLATSVPEPSSYGMLLAGLAVISFIGLKRGSRLAGAT
>Mature_313_residues
MNETSRSLRVAVLAAVLFLLGFNTAYASTLASNLELMEAQSPIDIRSNSTYYGNLPKLNFNLNSDTALTVINNGSPDHES
TIRANVSPGGGTLMLSGHQWNLAQFHFHTPSEHLINGRASPMEMHLVFSDAANNLLVVGRDIEQGLFKNQALAPIFSDLP
KTTEETLNIEHFNLNNLLPDYLGSFRYSGSLTTPPFTEGVSWVELASPLYLSGSQINAFKSLFPEGNSREIQDLNGRIVL
TDVPGFVSIHDDSDPNLLGTLIPGLEASVSVTADLSKLATSVPEPSSYGMLLAGLAVISFIGLKRGSRLAGAT

Specific function: Reversible hydration of carbon dioxide [H]

COG id: COG3338

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-carbonic anhydrase family [H]

Homologues:

Organism=Homo sapiens, GI6005723, Length=236, Percent_Identity=31.7796610169492, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4502521, Length=208, Percent_Identity=31.25, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4885101, Length=237, Percent_Identity=32.0675105485232, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI169636420, Length=248, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4557395, Length=208, Percent_Identity=30.7692307692308, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI6912284, Length=240, Percent_Identity=32.9166666666667, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI62240989, Length=171, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI22027500, Length=216, Percent_Identity=31.4814814814815, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI38348436, Length=236, Percent_Identity=30.0847457627119, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI194097398, Length=180, Percent_Identity=34.4444444444444, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI258679498, Length=234, Percent_Identity=28.6324786324786, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI192447434, Length=234, Percent_Identity=28.6324786324786, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI192447432, Length=234, Percent_Identity=28.6324786324786, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI192447430, Length=234, Percent_Identity=28.6324786324786, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4502517, Length=234, Percent_Identity=28.6324786324786, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4502515, Length=240, Percent_Identity=28.3333333333333, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI45935383, Length=240, Percent_Identity=28.3333333333333, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71995280, Length=237, Percent_Identity=29.535864978903, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17569163, Length=230, Percent_Identity=28.695652173913, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17569165, Length=232, Percent_Identity=28.448275862069, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24645604, Length=234, Percent_Identity=29.0598290598291, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358169, Length=244, Percent_Identity=31.5573770491803, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001148
- InterPro:   IPR018338
- InterPro:   IPR018340 [H]

Pfam domain/function: PF00194 Carb_anhydrase [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 33677; Mature: 33677

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS51144 ALPHA_CA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETSRSLRVAVLAAVLFLLGFNTAYASTLASNLELMEAQSPIDIRSNSTYYGNLPKLNF
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHEECCCCCCEECCCCEEECCCCEEEE
NLNSDTALTVINNGSPDHESTIRANVSPGGGTLMLSGHQWNLAQFHFHTPSEHLINGRAS
ECCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEEEECCHHHHHCCCCC
PMEMHLVFSDAANNLLVVGRDIEQGLFKNQALAPIFSDLPKTTEETLNIEHFNLNNLLPD
CEEEEEEEECCCCCEEEEECCHHHHHHCCCCHHHHHHHCCCCHHHHEEEEEEEHHHCCHH
YLGSFRYSGSLTTPPFTEGVSWVELASPLYLSGSQINAFKSLFPEGNSREIQDLNGRIVL
HHHCEEECCCCCCCCHHHCCCHHHHCCCEEECCCHHHHHHHHCCCCCCCHHHHCCCEEEE
TDVPGFVSIHDDSDPNLLGTLIPGLEASVSVTADLSKLATSVPEPSSYGMLLAGLAVISF
EECCCEEEEECCCCCCCHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHH
IGLKRGSRLAGAT
HHHCCCCCCCCCC
>Mature Secondary Structure
MNETSRSLRVAVLAAVLFLLGFNTAYASTLASNLELMEAQSPIDIRSNSTYYGNLPKLNF
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHEECCCCCCEECCCCEEECCCCEEEE
NLNSDTALTVINNGSPDHESTIRANVSPGGGTLMLSGHQWNLAQFHFHTPSEHLINGRAS
ECCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEEEECCHHHHHCCCCC
PMEMHLVFSDAANNLLVVGRDIEQGLFKNQALAPIFSDLPKTTEETLNIEHFNLNNLLPD
CEEEEEEEECCCCCEEEEECCHHHHHHCCCCHHHHHHHCCCCHHHHEEEEEEEHHHCCHH
YLGSFRYSGSLTTPPFTEGVSWVELASPLYLSGSQINAFKSLFPEGNSREIQDLNGRIVL
HHHCEEECCCCCCCCHHHCCCHHHHCCCEEECCCHHHHHHHHCCCCCCCHHHHCCCEEEE
TDVPGFVSIHDDSDPNLLGTLIPGLEASVSVTADLSKLATSVPEPSSYGMLLAGLAVISF
EECCCEEEEECCCCCCCHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHH
IGLKRGSRLAGAT
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9811652 [H]