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The map label for this gene is 82701542

Identifier: 82701542

GI number: 82701542

Start: 451768

End: 452646

Strand: Reverse

Name: 82701542

Synonym: Nmul_A0408

Alternate gene names: NA

Gene position: 452646-451768 (Counterclockwise)

Preceding gene: 82701543

Following gene: 82701541

Centisome position: 14.22

GC content: 53.36

Gene sequence:

>879_bases
ATGAAGACACCACGAGTCATTGCTGAAATCGGCTGTAATCATAAAGGGGATATCGAAATTGCAAGAGAGATGATCGGAAT
CGCCGCGACATTCGCCAAATGCGATTTCGTGAAATTTCAAAAGCGTTCGAACAGGGAATTATTGACGCCCGAGGAATATA
ACGCGCACCATCCAAATCCTCAAAACAGTTATGGCGACAGCTACGGCGCTCATCGTGAATTCCTCGAGTTTGATGTGGAT
CAGCACCGCCAATTGCAGCAATGGTGCCAAGAGTTTGGGATCGGTTATTCGACGTCGGTCTGGGATCTGACTTCGGCAAA
GGAGATTGCCCGCCTCAACCCAGAGTTCATCAAGATACCTTCGGCGTGCAACCTCAATTTCCCCATGCTGGCATATCTTG
CCACCGATTACGCCGGGGATATTCACATATCCGTCGGCATGACCACTCCCGCCGAACAGGAGCAGGTCGTGCAATGGATG
GAACGCCACGGTGCTGCTGGTCGAGTCGTCCTCTACGCATGTACATCCGGATATCCAGTTCCGTTCGACCAAGTCTGTCT
GCTGGAAATCCAGTCACTGAGGGACAGGTTCGGCTCGCGCGTCAAGGAGGTTGGATTTTCCGGCCACCACCTGGGTATTG
CCATCGACATTGCGACTGTGGTCCTGGGGGCATCCTGGATCGAACGTCATTTCACGCTGGACCGGACCTGGAAGGGAACC
GATCATGCCGCTTCGCTGGAGCCCGACGGATTGCGCAGGCTGGTCCGTGATGTTCGCAATGTCTGCAAGACCCTGAAGTT
CAAGGAGGGAGACATGACGGAAATCGAGCTTGCACAACGCGACAAACTCAAGCGCGTACAAGGGGTTCACTTTAACTGA

Upstream 100 bases:

>100_bases
GATCTTCCTTTTCAGAAAGCTTTGCTATAGTGGAGGGTTCGCAAACGGTGGGCTGGAGTCATATTCATTTTCTTTTATTC
AGGGGTTTGATCGCATTTTT

Downstream 100 bases:

>100_bases
TGCGCTGGGTAGCTTTCGCGCCTTTGCATGGAAATTTCGGGCCGGTTTCCCGAAGCAGCGCACGCAGCATGGCGGGAAGG
CCATTATTTTCCTGGAGCTT

Product: N-acylneuraminate-9-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKTPRVIAEIGCNHKGDIEIAREMIGIAATFAKCDFVKFQKRSNRELLTPEEYNAHHPNPQNSYGDSYGAHREFLEFDVD
QHRQLQQWCQEFGIGYSTSVWDLTSAKEIARLNPEFIKIPSACNLNFPMLAYLATDYAGDIHISVGMTTPAEQEQVVQWM
ERHGAAGRVVLYACTSGYPVPFDQVCLLEIQSLRDRFGSRVKEVGFSGHHLGIAIDIATVVLGASWIERHFTLDRTWKGT
DHAASLEPDGLRRLVRDVRNVCKTLKFKEGDMTEIELAQRDKLKRVQGVHFN

Sequences:

>Translated_292_residues
MKTPRVIAEIGCNHKGDIEIAREMIGIAATFAKCDFVKFQKRSNRELLTPEEYNAHHPNPQNSYGDSYGAHREFLEFDVD
QHRQLQQWCQEFGIGYSTSVWDLTSAKEIARLNPEFIKIPSACNLNFPMLAYLATDYAGDIHISVGMTTPAEQEQVVQWM
ERHGAAGRVVLYACTSGYPVPFDQVCLLEIQSLRDRFGSRVKEVGFSGHHLGIAIDIATVVLGASWIERHFTLDRTWKGT
DHAASLEPDGLRRLVRDVRNVCKTLKFKEGDMTEIELAQRDKLKRVQGVHFN
>Mature_292_residues
MKTPRVIAEIGCNHKGDIEIAREMIGIAATFAKCDFVKFQKRSNRELLTPEEYNAHHPNPQNSYGDSYGAHREFLEFDVD
QHRQLQQWCQEFGIGYSTSVWDLTSAKEIARLNPEFIKIPSACNLNFPMLAYLATDYAGDIHISVGMTTPAEQEQVVQWM
ERHGAAGRVVLYACTSGYPVPFDQVCLLEIQSLRDRFGSRVKEVGFSGHHLGIAIDIATVVLGASWIERHFTLDRTWKGT
DHAASLEPDGLRRLVRDVRNVCKTLKFKEGDMTEIELAQRDKLKRVQGVHFN

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=285, Percent_Identity=38.2456140350877, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI21357081, Length=288, Percent_Identity=37.5, Blast_Score=168, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 33137; Mature: 33137

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPRVIAEIGCNHKGDIEIAREMIGIAATFAKCDFVKFQKRSNRELLTPEEYNAHHPNP
CCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QNSYGDSYGAHREFLEFDVDQHRQLQQWCQEFGIGYSTSVWDLTSAKEIARLNPEFIKIP
CCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHEECC
SACNLNFPMLAYLATDYAGDIHISVGMTTPAEQEQVVQWMERHGAAGRVVLYACTSGYPV
CCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCC
PFDQVCLLEIQSLRDRFGSRVKEVGFSGHHLGIAIDIATVVLGASWIERHFTLDRTWKGT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCC
DHAASLEPDGLRRLVRDVRNVCKTLKFKEGDMTEIELAQRDKLKRVQGVHFN
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKTPRVIAEIGCNHKGDIEIAREMIGIAATFAKCDFVKFQKRSNRELLTPEEYNAHHPNP
CCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QNSYGDSYGAHREFLEFDVDQHRQLQQWCQEFGIGYSTSVWDLTSAKEIARLNPEFIKIP
CCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHEECC
SACNLNFPMLAYLATDYAGDIHISVGMTTPAEQEQVVQWMERHGAAGRVVLYACTSGYPV
CCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCC
PFDQVCLLEIQSLRDRFGSRVKEVGFSGHHLGIAIDIATVVLGASWIERHFTLDRTWKGT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCC
DHAASLEPDGLRRLVRDVRNVCKTLKFKEGDMTEIELAQRDKLKRVQGVHFN
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]