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The map label for this gene is kdsC [H]

Identifier: 82701541

GI number: 82701541

Start: 450563

End: 451768

Strand: Reverse

Name: kdsC [H]

Synonym: Nmul_A0407

Alternate gene names: 82701541

Gene position: 451768-450563 (Counterclockwise)

Preceding gene: 82701542

Following gene: 82701533

Centisome position: 14.19

GC content: 54.56

Gene sequence:

>1206_bases
ATGCGCTGGGTAGCTTTCGCGCCTTTGCATGGAAATTTCGGGCCGGTTTCCCGAAGCAGCGCACGCAGCATGGCGGGAAG
GCCATTATTTTCCTGGAGCTTGGAGCAGGCCGTCATATCGGGATGTTTCGACACCATTTACGTAACTGCCGACCCGCCTG
TCATTCGAAAACGGATAGTGGAAGAATTTTCGCGAGCCGACACGATAATCGAGATTCTCGATTGCAGTGGCGCAACCCGT
ACGGGCGTAGAGAATTGGACCAGTCTCCTACACACGTTTCAGCAGAAGATCCCCTTCGACGTCGTCTGTTCAATACAGGC
AGCCTCGCCCCTCACGCGTGCTGAAGATTTTCGTGCCGCTAAGCGCAAATTTCTTTCGGAAAATCTTGACTCGCTTCTGA
CAGCTGCGCCGTCCAGACGGTTTCTGTGGACAAGGATGGGAGAACCCGTCGGTCATGACCCGCTAAAATCCCGTGCGTCA
TGCGATGCATCGAATCCGGAGGGATACCTGCTGGAAAATGGCGCCTTCTATCTGACACATGAAAAATTACTTCGAGACAA
CGATCATTATCTGGGTGGACGCATGGGTATTCACGAGATGGCGCCCGAAACTGCGATCGAGATCACCGGAGAGGCTGGCT
GGAACATCGTGGAGCGTCTTTTACGGGAGCAGGAACGGGGGTCGGTCCAAGCCCGCGCGTCACGAATCAAGTTTCTGGTA
CTCGATGTGGACGGAACGTTGACGGATGCGGGAATGTATTACGGCCCCGCCGGCGAAGCCTTGAAAAAATTCAATACTCG
CGACGCCCATGGTTTGCAACGGTTGCGTGAACATGGCCTCGGGGTTTGCGTAATCACCACCGAGACTAGTCCTTCCGTTG
AAGCAAGGATGAGAAAATTGCGCATCGACGAATACTACCCGGGCATAAGCGATAAATTTCCTCTCCTCCTAAAGCTTTCC
AAACGCTGGGGGGTTCCTCTGGAAAATATCGGGTATGTGGGTGATGACCTCAGCGATCTGGAATGCCTGAGCCGCGTAGG
CGTTGCCTTCTGCCCGGCGGATGCTGTCCCCCTGGTCGTGCGGCAGGCCCATTATATGTGTGAATATTCGGGTGGCCACG
GCGCGGTTCGCGAGGTATGCGACTTGATTCTCCGATCAAGAGAAACCATACGACATGACTCCGCTGAAGCGGAAGCGTAC
TCATGA

Upstream 100 bases:

>100_bases
ATGTCTGCAAGACCCTGAAGTTCAAGGAGGGAGACATGACGGAAATCGAGCTTGCACAACGCGACAAACTCAAGCGCGTA
CAAGGGGTTCACTTTAACTG

Downstream 100 bases:

>100_bases
TCCGCCTGGAAGAATTGTTTACGCATACCGGACGCTATATCGTGTGCCGCGCTCAATCCCGGCTTTTGATGTCGAATTCC
GCTCGTGATTGCTTCACTGT

Product: phosphatase kdsC

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MRWVAFAPLHGNFGPVSRSSARSMAGRPLFSWSLEQAVISGCFDTIYVTADPPVIRKRIVEEFSRADTIIEILDCSGATR
TGVENWTSLLHTFQQKIPFDVVCSIQAASPLTRAEDFRAAKRKFLSENLDSLLTAAPSRRFLWTRMGEPVGHDPLKSRAS
CDASNPEGYLLENGAFYLTHEKLLRDNDHYLGGRMGIHEMAPETAIEITGEAGWNIVERLLREQERGSVQARASRIKFLV
LDVDGTLTDAGMYYGPAGEALKKFNTRDAHGLQRLREHGLGVCVITTETSPSVEARMRKLRIDEYYPGISDKFPLLLKLS
KRWGVPLENIGYVGDDLSDLECLSRVGVAFCPADAVPLVVRQAHYMCEYSGGHGAVREVCDLILRSRETIRHDSAEAEAY
S

Sequences:

>Translated_401_residues
MRWVAFAPLHGNFGPVSRSSARSMAGRPLFSWSLEQAVISGCFDTIYVTADPPVIRKRIVEEFSRADTIIEILDCSGATR
TGVENWTSLLHTFQQKIPFDVVCSIQAASPLTRAEDFRAAKRKFLSENLDSLLTAAPSRRFLWTRMGEPVGHDPLKSRAS
CDASNPEGYLLENGAFYLTHEKLLRDNDHYLGGRMGIHEMAPETAIEITGEAGWNIVERLLREQERGSVQARASRIKFLV
LDVDGTLTDAGMYYGPAGEALKKFNTRDAHGLQRLREHGLGVCVITTETSPSVEARMRKLRIDEYYPGISDKFPLLLKLS
KRWGVPLENIGYVGDDLSDLECLSRVGVAFCPADAVPLVVRQAHYMCEYSGGHGAVREVCDLILRSRETIRHDSAEAEAY
S
>Mature_401_residues
MRWVAFAPLHGNFGPVSRSSARSMAGRPLFSWSLEQAVISGCFDTIYVTADPPVIRKRIVEEFSRADTIIEILDCSGATR
TGVENWTSLLHTFQQKIPFDVVCSIQAASPLTRAEDFRAAKRKFLSENLDSLLTAAPSRRFLWTRMGEPVGHDPLKSRAS
CDASNPEGYLLENGAFYLTHEKLLRDNDHYLGGRMGIHEMAPETAIEITGEAGWNIVERLLREQERGSVQARASRIKFLV
LDVDGTLTDAGMYYGPAGEALKKFNTRDAHGLQRLREHGLGVCVITTETSPSVEARMRKLRIDEYYPGISDKFPLLLKLS
KRWGVPLENIGYVGDDLSDLECLSRVGVAFCPADAVPLVVRQAHYMCEYSGGHGAVREVCDLILRSRETIRHDSAEAEAY
S

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=380, Percent_Identity=27.6315789473684, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI2367202, Length=159, Percent_Identity=41.5094339622642, Blast_Score=124, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 44667; Mature: 44667

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWVAFAPLHGNFGPVSRSSARSMAGRPLFSWSLEQAVISGCFDTIYVTADPPVIRKRIV
CCEEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHH
EEFSRADTIIEILDCSGATRTGVENWTSLLHTFQQKIPFDVVCSIQAASPLTRAEDFRAA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
KRKFLSENLDSLLTAAPSRRFLWTRMGEPVGHDPLKSRASCDASNPEGYLLENGAFYLTH
HHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHCCCCCCCCCCEEEECCEEEEEH
EKLLRDNDHYLGGRMGIHEMAPETAIEITGEAGWNIVERLLREQERGSVQARASRIKFLV
HHHHCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHCEEEEEE
LDVDGTLTDAGMYYGPAGEALKKFNTRDAHGLQRLREHGLGVCVITTETSPSVEARMRKL
EECCCCEECCCCEECCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHH
RIDEYYPGISDKFPLLLKLSKRWGVPLENIGYVGDDLSDLECLSRVGVAFCPADAVPLVV
HHHHHCCCCCCCCCHHEEEHHHCCCCHHHCCCCCCCHHHHHHHHHCCEEECCCCHHHHHH
RQAHYMCEYSGGHGAVREVCDLILRSRETIRHDSAEAEAYS
HHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRWVAFAPLHGNFGPVSRSSARSMAGRPLFSWSLEQAVISGCFDTIYVTADPPVIRKRIV
CCEEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHH
EEFSRADTIIEILDCSGATRTGVENWTSLLHTFQQKIPFDVVCSIQAASPLTRAEDFRAA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
KRKFLSENLDSLLTAAPSRRFLWTRMGEPVGHDPLKSRASCDASNPEGYLLENGAFYLTH
HHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHCCCCCCCCCCEEEECCEEEEEH
EKLLRDNDHYLGGRMGIHEMAPETAIEITGEAGWNIVERLLREQERGSVQARASRIKFLV
HHHHCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHCEEEEEE
LDVDGTLTDAGMYYGPAGEALKKFNTRDAHGLQRLREHGLGVCVITTETSPSVEARMRKL
EECCCCEECCCCEECCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHH
RIDEYYPGISDKFPLLLKLSKRWGVPLENIGYVGDDLSDLECLSRVGVAFCPADAVPLVV
HHHHHCCCCCCCCCHHEEEHHHCCCCHHHCCCCCCCHHHHHHHHHCCEEECCCCHHHHHH
RQAHYMCEYSGGHGAVREVCDLILRSRETIRHDSAEAEAYS
HHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]