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The map label for this gene is argA [H]

Identifier: 82701514

GI number: 82701514

Start: 416289

End: 417617

Strand: Direct

Name: argA [H]

Synonym: Nmul_A0380

Alternate gene names: 82701514

Gene position: 416289-417617 (Clockwise)

Preceding gene: 82701513

Following gene: 82701515

Centisome position: 13.07

GC content: 55.46

Gene sequence:

>1329_bases
ATGGATTTTGTGACCTGGTTCCGGTCGGTAGCGCCTTATATCAACAGCTTCCGTCATAAAGTTTTCGTAGTCGCTTTCGG
CGGGGAAGTCGTTGCGGACGGGAAATTCATCGAACTCGTACACGATCTCAATCTGCTCGCCAGCTTAGGCGTACGTCTGG
TGCTGGTGCACGGTGCGCGCCCACAGATCGAGTCGCGCTTAAACGAACATGATCTGCAGACGACATATATACGGGGTATG
CGCGTCACCGATGCGGCTGCGTTGCAGTGTGTCAAGGAATCGATAGGGCGGGTACGTGTCGAAATCGAAGCGCTGCTGTC
AATGGGTTTGCCGAATTCACCGATGGCCAACGCTGCAATTCGCGTCGCCAGCGGCAACTTTGTTACTGCACGGCCAATCG
GCGTGATAGAGGGTATTGACCTGATGCATACCGGAGAAGTACGCAAGGTGGATATTTCCGCCATCCGCTCGCGGCTCGAG
CAGGGTGAGTTGGCATTACTGTCGCCGCTTGGCTACTCCCCTACCGGCGAGATCTTTAATTTGACACTGGAAAATGTCGC
AGCTGAGGCTGCAATCGCTCTCAAGGCCGAGAAACTCATATTTCTGATGGATACCCAGGGGATCGAAAAGAGCACTGCAG
ACAGCGAACAGGCGTTGCTGCTGCGGGAACTGACGGTGGGGGAGGGCAGGAGCCTACTTAAGGAGTTTGGGAGGAAAATG
GTACAACTTGCCGAGGATGCGCAGCTTTATCTGCCTTTTGCCCTGCACGCCTGTGAACGCGGAGTATCGCGCGTCCACCT
CATAAGCCGGCACGTGGATGGCGCTATTTTACAGGAGCTATTCACCCACAGCGGCATCGGGACAATGATATCCGAAGGTC
CGTTGCAAAACCTGCGGGATGCCCGAATAGAGGACGTGGGCGCGATTTTGCAACTGATCGAGCCTCTCGAAGCGGACGGG
ACGTTGGTGCGGCGGAGTCGCGAGTTGCTGGAGATGGAGATTGATCGTTTCGTCGTGATCGAGCATGATCGCATGATTGT
CGGCTGTGCGGCGCTCTATCCTTTTCCGGACGACATGGCGGGCGAGCTCGCCTGTCTTACCGTTCATCCTGACTATCGTA
GTGCGGGCTGTGGAGATGCGCTGCTCAAGGCTATCGAGGCGAAGGCGAGATCCCAGGGCAGTAAAAAACTGTTCGTCCTT
ACCACCCGGACAGCCCACTGGTTCGTCGAGCGCGGCTTCCTTTCAGCAGACGTCAGTCAATTACCCAAGGTGAAGCAGGG
GCTATACAATTATCAACGGCGCTCGAAGGTATTTATGAAACCCCTTTAA

Upstream 100 bases:

>100_bases
GTTTCATTCCATTGCGTCTGGGTCACCGCATACTGCGAACGGAGAGCGCCGCACTGGCGGCAGTGGGAGCAATGCAGGCG
CTATGGGGTGATTATTGATC

Downstream 100 bases:

>100_bases
CCAGCCCTCAGATTCTGGCTGCTGGAGCGACTATCCTGTCGCGTAATCAAACGGTGCGGCGCACGGCGCTCTGGTGGTCT
GCCTTTTGTTATATTTCGGA

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MDFVTWFRSVAPYINSFRHKVFVVAFGGEVVADGKFIELVHDLNLLASLGVRLVLVHGARPQIESRLNEHDLQTTYIRGM
RVTDAAALQCVKESIGRVRVEIEALLSMGLPNSPMANAAIRVASGNFVTARPIGVIEGIDLMHTGEVRKVDISAIRSRLE
QGELALLSPLGYSPTGEIFNLTLENVAAEAAIALKAEKLIFLMDTQGIEKSTADSEQALLLRELTVGEGRSLLKEFGRKM
VQLAEDAQLYLPFALHACERGVSRVHLISRHVDGAILQELFTHSGIGTMISEGPLQNLRDARIEDVGAILQLIEPLEADG
TLVRRSRELLEMEIDRFVVIEHDRMIVGCAALYPFPDDMAGELACLTVHPDYRSAGCGDALLKAIEAKARSQGSKKLFVL
TTRTAHWFVERGFLSADVSQLPKVKQGLYNYQRRSKVFMKPL

Sequences:

>Translated_442_residues
MDFVTWFRSVAPYINSFRHKVFVVAFGGEVVADGKFIELVHDLNLLASLGVRLVLVHGARPQIESRLNEHDLQTTYIRGM
RVTDAAALQCVKESIGRVRVEIEALLSMGLPNSPMANAAIRVASGNFVTARPIGVIEGIDLMHTGEVRKVDISAIRSRLE
QGELALLSPLGYSPTGEIFNLTLENVAAEAAIALKAEKLIFLMDTQGIEKSTADSEQALLLRELTVGEGRSLLKEFGRKM
VQLAEDAQLYLPFALHACERGVSRVHLISRHVDGAILQELFTHSGIGTMISEGPLQNLRDARIEDVGAILQLIEPLEADG
TLVRRSRELLEMEIDRFVVIEHDRMIVGCAALYPFPDDMAGELACLTVHPDYRSAGCGDALLKAIEAKARSQGSKKLFVL
TTRTAHWFVERGFLSADVSQLPKVKQGLYNYQRRSKVFMKPL
>Mature_442_residues
MDFVTWFRSVAPYINSFRHKVFVVAFGGEVVADGKFIELVHDLNLLASLGVRLVLVHGARPQIESRLNEHDLQTTYIRGM
RVTDAAALQCVKESIGRVRVEIEALLSMGLPNSPMANAAIRVASGNFVTARPIGVIEGIDLMHTGEVRKVDISAIRSRLE
QGELALLSPLGYSPTGEIFNLTLENVAAEAAIALKAEKLIFLMDTQGIEKSTADSEQALLLRELTVGEGRSLLKEFGRKM
VQLAEDAQLYLPFALHACERGVSRVHLISRHVDGAILQELFTHSGIGTMISEGPLQNLRDARIEDVGAILQLIEPLEADG
TLVRRSRELLEMEIDRFVVIEHDRMIVGCAALYPFPDDMAGELACLTVHPDYRSAGCGDALLKAIEAKARSQGSKKLFVL
TTRTAHWFVERGFLSADVSQLPKVKQGLYNYQRRSKVFMKPL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=441, Percent_Identity=47.3922902494331, Blast_Score=414, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6320913, Length=299, Percent_Identity=24.7491638795987, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 48824; Mature: 48824

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFVTWFRSVAPYINSFRHKVFVVAFGGEVVADGKFIELVHDLNLLASLGVRLVLVHGAR
CCHHHHHHHHHHHHHHHCCEEEEEEECCEEEECCHHHHHHHHHHHHHHCCEEEEEEECCC
PQIESRLNEHDLQTTYIRGMRVTDAAALQCVKESIGRVRVEIEALLSMGLPNSPMANAAI
HHHHHHCCHHCCHHHHHCCEEEHHHHHHHHHHHHHHHEEHHHHHHHHCCCCCCCCCCCEE
RVASGNFVTARPIGVIEGIDLMHTGEVRKVDISAIRSRLEQGELALLSPLGYSPTGEIFN
EEECCCEEEECCCCCCCCCCEEECCCCEEEEHHHHHHHHCCCCEEEECCCCCCCCCCEEE
LTLENVAAEAAIALKAEKLIFLMDTQGIEKSTADSEQALLLRELTVGEGRSLLKEFGRKM
EEHHHHHHHHHHEEEECEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
VQLAEDAQLYLPFALHACERGVSRVHLISRHVDGAILQELFTHSGIGTMISEGPLQNLRD
HHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHCCCCHHHHHH
ARIEDVGAILQLIEPLEADGTLVRRSRELLEMEIDRFVVIEHDRMIVGCAALYPFPDDMA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEEEEECCCCCCCC
GELACLTVHPDYRSAGCGDALLKAIEAKARSQGSKKLFVLTTRTAHWFVERGFLSADVSQ
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHCCCCCCCHHH
LPKVKQGLYNYQRRSKVFMKPL
CHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDFVTWFRSVAPYINSFRHKVFVVAFGGEVVADGKFIELVHDLNLLASLGVRLVLVHGAR
CCHHHHHHHHHHHHHHHCCEEEEEEECCEEEECCHHHHHHHHHHHHHHCCEEEEEEECCC
PQIESRLNEHDLQTTYIRGMRVTDAAALQCVKESIGRVRVEIEALLSMGLPNSPMANAAI
HHHHHHCCHHCCHHHHHCCEEEHHHHHHHHHHHHHHHEEHHHHHHHHCCCCCCCCCCCEE
RVASGNFVTARPIGVIEGIDLMHTGEVRKVDISAIRSRLEQGELALLSPLGYSPTGEIFN
EEECCCEEEECCCCCCCCCCEEECCCCEEEEHHHHHHHHCCCCEEEECCCCCCCCCCEEE
LTLENVAAEAAIALKAEKLIFLMDTQGIEKSTADSEQALLLRELTVGEGRSLLKEFGRKM
EEHHHHHHHHHHEEEECEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
VQLAEDAQLYLPFALHACERGVSRVHLISRHVDGAILQELFTHSGIGTMISEGPLQNLRD
HHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHCCCCHHHHHH
ARIEDVGAILQLIEPLEADGTLVRRSRELLEMEIDRFVVIEHDRMIVGCAALYPFPDDMA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEEEEECCCCCCCC
GELACLTVHPDYRSAGCGDALLKAIEAKARSQGSKKLFVLTTRTAHWFVERGFLSADVSQ
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHCCCCCCCHHH
LPKVKQGLYNYQRRSKVFMKPL
CHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]