| Definition | Nitrosospira multiformis ATCC 25196 chromosome, complete genome. |
|---|---|
| Accession | NC_007614 |
| Length | 3,184,243 |
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The map label for this gene is gdhII [H]
Identifier: 82701470
GI number: 82701470
Start: 367955
End: 368695
Strand: Reverse
Name: gdhII [H]
Synonym: Nmul_A0336
Alternate gene names: 82701470
Gene position: 368695-367955 (Counterclockwise)
Preceding gene: 82701474
Following gene: 82701462
Centisome position: 11.58
GC content: 57.49
Gene sequence:
>741_bases ATGCAAGGGAAAGTGATACTCGTCACAGGGGGAGCAAGGCGCGTAGGCGCCGCCACCTGCCGCCGCCTGCACTCACAGGG AGCAAATCTGGCCGTGCATTACAGAAGCTCTATCGAGGAGGCGCAGACATTGCAGGCCGAACTGAACCGGACGCGATCCG GTTCAGTTGCTCTGGTACAAGCCGATCTGCTGGATATTGCGCGCCTGCCGCAACTGGTAGCTGAAACCGTAGAGCGATTC GGGAAGCTGGATGCGCTGGTCAACAATGCCTCCAGCTTTTTTCCAACTCCATTCGGCGAAATCACTGCTGATATGTGGGA CGATCTGATGGGAAGCAACCTGAAAGCCCCCCTGTTTCTATCCCAGGCAGCGGCCTCCCAATTAAGAAAACAGCACGGCT GCATCGTCAATATCGTTGACATTCATTCGGAATGGCCGCTCAAGAATTACGTGGTATACAACGCCGCCAAGGGCGGACTA GCCTCACTGACCCGATCGCTGGCGCAGGAGCTTGCGCCGGAAGTCCGGGTAAATGGCATCTCACCCGGTCCCATCCTGTG GCCGGAAGCGGGGGAATGGGCGGATGAGGCATCGCGCCAGCACATCATTGACAGGACGCTGCTGAAACGCACGGGTGAGC CGGATGACATTGCCCGGACCGTTGCTTTCCTGATTGCAGATGCGCCTTACATCACTGGCCAGATCATTGCCGTGGATGGG GGACGAAGTGTGAATCTATAG
Upstream 100 bases:
>100_bases TAAGTCCCTCTTTTGAGGCAGACACTCTCGTACCTGCTCCTGGCGGCCGGTTTCCCGTTATAAAAAATCGAATCAATCCG CAAGTGTAGAGGAGATAGCG
Downstream 100 bases:
>100_bases TCAGGTTGCAAAAATCATTGGACGTCATAATCCCCTAAAGGAAGAATCTTTCCAGTTTCCTCGGGCCTGGGGAATGAACT CGGCGGGAAGCAAAAGGTCG
Product: pteridine reductase
Products: NA
Alternate protein names: GLCDH-II [H]
Number of amino acids: Translated: 246; Mature: 246
Protein sequence:
>246_residues MQGKVILVTGGARRVGAATCRRLHSQGANLAVHYRSSIEEAQTLQAELNRTRSGSVALVQADLLDIARLPQLVAETVERF GKLDALVNNASSFFPTPFGEITADMWDDLMGSNLKAPLFLSQAAASQLRKQHGCIVNIVDIHSEWPLKNYVVYNAAKGGL ASLTRSLAQELAPEVRVNGISPGPILWPEAGEWADEASRQHIIDRTLLKRTGEPDDIARTVAFLIADAPYITGQIIAVDG GRSVNL
Sequences:
>Translated_246_residues MQGKVILVTGGARRVGAATCRRLHSQGANLAVHYRSSIEEAQTLQAELNRTRSGSVALVQADLLDIARLPQLVAETVERF GKLDALVNNASSFFPTPFGEITADMWDDLMGSNLKAPLFLSQAAASQLRKQHGCIVNIVDIHSEWPLKNYVVYNAAKGGL ASLTRSLAQELAPEVRVNGISPGPILWPEAGEWADEASRQHIIDRTLLKRTGEPDDIARTVAFLIADAPYITGQIIAVDG GRSVNL >Mature_246_residues MQGKVILVTGGARRVGAATCRRLHSQGANLAVHYRSSIEEAQTLQAELNRTRSGSVALVQADLLDIARLPQLVAETVERF GKLDALVNNASSFFPTPFGEITADMWDDLMGSNLKAPLFLSQAAASQLRKQHGCIVNIVDIHSEWPLKNYVVYNAAKGGL ASLTRSLAQELAPEVRVNGISPGPILWPEAGEWADEASRQHIIDRTLLKRTGEPDDIARTVAFLIADAPYITGQIIAVDG GRSVNL
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=35.5212355212355, Blast_Score=125, Evalue=4e-29, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=35.6, Blast_Score=113, Evalue=1e-25, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=30.1587301587302, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=31.0483870967742, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=30.5555555555556, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=29.5081967213115, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI59889578, Length=178, Percent_Identity=35.9550561797753, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=30.2788844621514, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=26.1904761904762, Blast_Score=74, Evalue=8e-14, Organism=Homo sapiens, GI4503301, Length=250, Percent_Identity=28, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=31.3829787234043, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=33.5106382978723, Blast_Score=69, Evalue=3e-12, Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=30.4526748971193, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=33.1983805668016, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=30.7377049180328, Blast_Score=97, Evalue=7e-22, Organism=Escherichia coli, GI1787891, Length=251, Percent_Identity=29.0836653386454, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=29.4354838709677, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=31.5352697095436, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=29.6442687747036, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=28.2258064516129, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=28.6885245901639, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=28.1368821292776, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=28.3400809716599, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787545, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=27.0588235294118, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=26.6304347826087, Blast_Score=64, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=35.361216730038, Blast_Score=123, Evalue=8e-29, Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=30.3643724696356, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=33.4600760456274, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=31.496062992126, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=30.6772908366534, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=32.1969696969697, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=26.1044176706827, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI71994604, Length=182, Percent_Identity=30.2197802197802, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=29.3893129770992, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=33.969465648855, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=31.6602316602317, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=30.9160305343511, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=33.2089552238806, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=31.8352059925094, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=30.0751879699248, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=30.4182509505703, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=29.2307692307692, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=29.5019157088123, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17508651, Length=256, Percent_Identity=32.421875, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=28.8888888888889, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560150, Length=271, Percent_Identity=28.0442804428044, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=29.2307692307692, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=28.7313432835821, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=27.6923076923077, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=27.6264591439689, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=28.5140562248996, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=26.6409266409266, Blast_Score=74, Evalue=6e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=27.4193548387097, Blast_Score=95, Evalue=1e-20, Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=33.6032388663968, Blast_Score=120, Evalue=6e-28, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=28.9156626506024, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=31.2, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=30.5555555555556, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=32.258064516129, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.6, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=32.156862745098, Blast_Score=88, Evalue=7e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.47 [H]
Molecular weight: Translated: 26603; Mature: 26603
Theoretical pI: Translated: 6.68; Mature: 6.68
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQGKVILVTGGARRVGAATCRRLHSQGANLAVHYRSSIEEAQTLQAELNRTRSGSVALVQ CCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEH ADLLDIARLPQLVAETVERFGKLDALVNNASSFFPTPFGEITADMWDDLMGSNLKAPLFL HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHCCCCCCCHHH SQAAASQLRKQHGCIVNIVDIHSEWPLKNYVVYNAAKGGLASLTRSLAQELAPEVRVNGI HHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEECCC SPGPILWPEAGEWADEASRQHIIDRTLLKRTGEPDDIARTVAFLIADAPYITGQIIAVDG CCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEC GRSVNL CCCCCC >Mature Secondary Structure MQGKVILVTGGARRVGAATCRRLHSQGANLAVHYRSSIEEAQTLQAELNRTRSGSVALVQ CCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEH ADLLDIARLPQLVAETVERFGKLDALVNNASSFFPTPFGEITADMWDDLMGSNLKAPLFL HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHCCCCCCCHHH SQAAASQLRKQHGCIVNIVDIHSEWPLKNYVVYNAAKGGLASLTRSLAQELAPEVRVNGI HHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEECCC SPGPILWPEAGEWADEASRQHIIDRTLLKRTGEPDDIARTVAFLIADAPYITGQIIAVDG CCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEC GRSVNL CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA