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The map label for this gene is atpB [H]

Identifier: 82701438

GI number: 82701438

Start: 327902

End: 328708

Strand: Direct

Name: atpB [H]

Synonym: Nmul_A0304

Alternate gene names: 82701438

Gene position: 327902-328708 (Clockwise)

Preceding gene: 82701437

Following gene: 82701439

Centisome position: 10.3

GC content: 54.4

Gene sequence:

>807_bases
ATGGCATCAGGCACAGAACTTACCCCAACTTCCTATATGTCGCATCACCTGACCAATCTGACGAGCTCGATCGGTGAGGG
TGAATTCTGGACGCTGCATGTGGATACGCTCGTCATGGCGGTGCTGACCGGTATCATCAGCCTCGGTTTTCTCTGGTGGG
TGGTGCGCGGTGCGACTTCGGGCGTCCCCAGCAAGCGCCAGGCATTCGTGGAGCTTGCCATCGAATTCATCGATAATCAG
GTCAAAAGCACTTTTCACGGAGATCGGCATGCATTTGTGGCGCCTGCTGCGCTCACCGTGTTTGTGTGGGTGCTCATGAT
GAACGCCATGGATTTCCTGCCGATCGATATCATGGCGAAGGTATACGAGCTGGTGGGGCTGCACAACTGGCGCAGCGTCC
CGACTGCCGATGTGAATACGACGTTCGCGCTGGCGCTCTCCGTGTGGCTCCTGATGATCTTTTTCAACATGAAAGTCAAG
GGCGTGGGCGGCTGGATACACGAACTGGTCTGCAGCCCTTTCGGCAAGAACCCTCTATTGTGGCCGGTCAATATCCTGTT
CAATCTGGTTGAATACGTCTCCAAGCCGCTTTCGCATTCATTGCGGCTGTACGGGAACATTTATGCAGGAGAAATCATTT
TTCTGCTGCTCGGCATGTGGGCTGCAACCGGCCTTGCCGGGACATTTTTCGGCACGCTGCTGAATGCAGGGTGGGCCATC
TTCCATATCTTGATCGTCACATTGCAGGCATTCATCTTCATGATGCTGACGGTGGTTTATCTTTCCATGGCGCACGAGTC
ACACTGA

Upstream 100 bases:

>100_bases
CTTCATACTGACGGTTCTGATCTTCGGGCTGGCATTGTTCGTAACGGATGATGCAAAGGTTGCGCAAATAAAGCAATAAA
CAGTTGAGATAGGCAAATAA

Downstream 100 bases:

>100_bases
TTCTGCGCTGCTGTTCTTAACCAATTTCAATTACTACTAGAGAGGAAAACCAGATGGAGAATTTGCAATTCCTGGCCATG
ATTCAGGCATACACGGGCAT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MASGTELTPTSYMSHHLTNLTSSIGEGEFWTLHVDTLVMAVLTGIISLGFLWWVVRGATSGVPSKRQAFVELAIEFIDNQ
VKSTFHGDRHAFVAPAALTVFVWVLMMNAMDFLPIDIMAKVYELVGLHNWRSVPTADVNTTFALALSVWLLMIFFNMKVK
GVGGWIHELVCSPFGKNPLLWPVNILFNLVEYVSKPLSHSLRLYGNIYAGEIIFLLLGMWAATGLAGTFFGTLLNAGWAI
FHILIVTLQAFIFMMLTVVYLSMAHESH

Sequences:

>Translated_268_residues
MASGTELTPTSYMSHHLTNLTSSIGEGEFWTLHVDTLVMAVLTGIISLGFLWWVVRGATSGVPSKRQAFVELAIEFIDNQ
VKSTFHGDRHAFVAPAALTVFVWVLMMNAMDFLPIDIMAKVYELVGLHNWRSVPTADVNTTFALALSVWLLMIFFNMKVK
GVGGWIHELVCSPFGKNPLLWPVNILFNLVEYVSKPLSHSLRLYGNIYAGEIIFLLLGMWAATGLAGTFFGTLLNAGWAI
FHILIVTLQAFIFMMLTVVYLSMAHESH
>Mature_267_residues
ASGTELTPTSYMSHHLTNLTSSIGEGEFWTLHVDTLVMAVLTGIISLGFLWWVVRGATSGVPSKRQAFVELAIEFIDNQV
KSTFHGDRHAFVAPAALTVFVWVLMMNAMDFLPIDIMAKVYELVGLHNWRSVPTADVNTTFALALSVWLLMIFFNMKVKG
VGGWIHELVCSPFGKNPLLWPVNILFNLVEYVSKPLSHSLRLYGNIYAGEIIFLLLGMWAATGLAGTFFGTLLNAGWAIF
HILIVTLQAFIFMMLTVVYLSMAHESH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=279, Percent_Identity=46.2365591397849, Blast_Score=221, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 29828; Mature: 29696

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGTELTPTSYMSHHLTNLTSSIGEGEFWTLHVDTLVMAVLTGIISLGFLWWVVRGATS
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVPSKRQAFVELAIEFIDNQVKSTFHGDRHAFVAPAALTVFVWVLMMNAMDFLPIDIMAK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VYELVGLHNWRSVPTADVNTTFALALSVWLLMIFFNMKVKGVGGWIHELVCSPFGKNPLL
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHCCCCCCCCC
WPVNILFNLVEYVSKPLSHSLRLYGNIYAGEIIFLLLGMWAATGLAGTFFGTLLNAGWAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHILIVTLQAFIFMMLTVVYLSMAHESH
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASGTELTPTSYMSHHLTNLTSSIGEGEFWTLHVDTLVMAVLTGIISLGFLWWVVRGATS
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVPSKRQAFVELAIEFIDNQVKSTFHGDRHAFVAPAALTVFVWVLMMNAMDFLPIDIMAK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VYELVGLHNWRSVPTADVNTTFALALSVWLLMIFFNMKVKGVGGWIHELVCSPFGKNPLL
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHCCCCCCCCC
WPVNILFNLVEYVSKPLSHSLRLYGNIYAGEIIFLLLGMWAATGLAGTFFGTLLNAGWAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHILIVTLQAFIFMMLTVVYLSMAHESH
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]