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The map label for this gene is wzc [C]

Identifier: 82701378

GI number: 82701378

Start: 261588

End: 262517

Strand: Direct

Name: wzc [C]

Synonym: Nmul_A0244

Alternate gene names: 82701378

Gene position: 261588-262517 (Clockwise)

Preceding gene: 82701377

Following gene: 82701380

Centisome position: 8.22

GC content: 53.12

Gene sequence:

>930_bases
ATGAATCCCGTAAGCGCCAGTTTGCCTGCCATCAAGCGGAGTCAGAATTCCAATTCCCGCGAGTCGTTCTTTGCTGGCCG
AACTCAAATCATTGGAAATAGCAGTTCGATCGGAGCTATTCTCGTCAATGCGGGAAGGCTATCCGAGGAGAATGTGACCC
GCATACTGGAAGCGCAAGTACAGCAGCAAAACCACTTTGGTGAAGCGGCCATATGCCTCGGCTTGCTCACGGAAGACGAT
GTGCGCTTTGCTCTTTCGCGCCAGTTTAACAATCTCTATCTGCCAGCAGGGGACAGCAGCCTCAGTCATCATTTAATTGC
GGCTTACAAACCGTTCAGTCCTGTCGTCGAACACCTGCGAAGCCTACGCAGCCAGCTCATGCTGCGCTGGTTCGAGCCGG
ATACTGACCGGAACGTGCTTGCCATTGTCAGCCCAGGGCTGGGAGAAGGTCGAAGCTTCATAGCTGCCAATCTTGCCATC
GTTTTTTCGCAGCTTGGCAAAAGTACATTGCTCATCGATGCAAATCTTCGGGCGCCCCGGCAGCAGGAATTCTTTAAAGT
GAATACAGGTGGGGGCTTATCCAGCTACCTTGCAGGCCGTGCTGGTTTGGAGAGCATTGTCAGAATTCCTTCATTGCTTG
GACTTTCTGTCCTGCCCGCGGGTGCAGTACCGCCAAATCCGCAAGAACTTATCGGTCGACCCGTTTTCGCGGATTTGCTG
CAATCGGTTGGCTGCGAGTTTGATGTCGTTATCGTGGATACCCCCTCAGCAAGCGAATACGGGGAAGCGCAAATCATCGC
AACCGAGGCCTCTGCTGCCTTGATTGTCCTTCGAAAGAATCATACCTCTCTATCACGCACCGTGGATCTTGCGCGACGTT
TCCAGCAGACGGGCGCTGCGGTAGTAGGTTCTGTGCTGAATGATTTTTGA

Upstream 100 bases:

>100_bases
TGCTGGCGGTAATGTCCGGCCCGTCTCGCAACAAGCTTTCGAGTCGTCTTCCCAAATTACCCAACCCGGAAACCAGTTAA
TACTCAAACGGAGCTACATC

Downstream 100 bases:

>100_bases
ACAATAAAGGCGGTATGGATTTAGGGTAATACCCCATGGATGGTTCGCGTGATCGAAATTCCACGAACATCAGGCGCTAA
ACGAAAGGGATGGCATATAT

Product: protein-tyrosine kinase

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: ORF6 [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNPVSASLPAIKRSQNSNSRESFFAGRTQIIGNSSSIGAILVNAGRLSEENVTRILEAQVQQQNHFGEAAICLGLLTEDD
VRFALSRQFNNLYLPAGDSSLSHHLIAAYKPFSPVVEHLRSLRSQLMLRWFEPDTDRNVLAIVSPGLGEGRSFIAANLAI
VFSQLGKSTLLIDANLRAPRQQEFFKVNTGGGLSSYLAGRAGLESIVRIPSLLGLSVLPAGAVPPNPQELIGRPVFADLL
QSVGCEFDVVIVDTPSASEYGEAQIIATEASAALIVLRKNHTSLSRTVDLARRFQQTGAAVVGSVLNDF

Sequences:

>Translated_309_residues
MNPVSASLPAIKRSQNSNSRESFFAGRTQIIGNSSSIGAILVNAGRLSEENVTRILEAQVQQQNHFGEAAICLGLLTEDD
VRFALSRQFNNLYLPAGDSSLSHHLIAAYKPFSPVVEHLRSLRSQLMLRWFEPDTDRNVLAIVSPGLGEGRSFIAANLAI
VFSQLGKSTLLIDANLRAPRQQEFFKVNTGGGLSSYLAGRAGLESIVRIPSLLGLSVLPAGAVPPNPQELIGRPVFADLL
QSVGCEFDVVIVDTPSASEYGEAQIIATEASAALIVLRKNHTSLSRTVDLARRFQQTGAAVVGSVLNDF
>Mature_309_residues
MNPVSASLPAIKRSQNSNSRESFFAGRTQIIGNSSSIGAILVNAGRLSEENVTRILEAQVQQQNHFGEAAICLGLLTEDD
VRFALSRQFNNLYLPAGDSSLSHHLIAAYKPFSPVVEHLRSLRSQLMLRWFEPDTDRNVLAIVSPGLGEGRSFIAANLAI
VFSQLGKSTLLIDANLRAPRQQEFFKVNTGGGLSSYLAGRAGLESIVRIPSLLGLSVLPAGAVPPNPQELIGRPVFADLL
QSVGCEFDVVIVDTPSASEYGEAQIIATEASAALIVLRKNHTSLSRTVDLARRFQQTGAAVVGSVLNDF

Specific function: Required For The Extracellular Polysaccharide Colanic Acid Synthesis. The Autophosphorylated Form Is Inactive. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=204, Percent_Identity=32.3529411764706, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787216, Length=305, Percent_Identity=28.5245901639344, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 33206; Mature: 33206

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVSASLPAIKRSQNSNSRESFFAGRTQIIGNSSSIGAILVNAGRLSEENVTRILEAQV
CCCCCCCCCHHHHCCCCCCHHHHHCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHHHH
QQQNHFGEAAICLGLLTEDDVRFALSRQFNNLYLPAGDSSLSHHLIAAYKPFSPVVEHLR
HHHCCCCCHHHHEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHH
SLRSQLMLRWFEPDTDRNVLAIVSPGLGEGRSFIAANLAIVFSQLGKSTLLIDANLRAPR
HHHHHHHEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCC
QQEFFKVNTGGGLSSYLAGRAGLESIVRIPSLLGLSVLPAGAVPPNPQELIGRPVFADLL
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHH
QSVGCEFDVVIVDTPSASEYGEAQIIATEASAALIVLRKNHTSLSRTVDLARRFQQTGAA
HHCCCCEEEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VVGSVLNDF
HHHHHHHCC
>Mature Secondary Structure
MNPVSASLPAIKRSQNSNSRESFFAGRTQIIGNSSSIGAILVNAGRLSEENVTRILEAQV
CCCCCCCCCHHHHCCCCCCHHHHHCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHHHH
QQQNHFGEAAICLGLLTEDDVRFALSRQFNNLYLPAGDSSLSHHLIAAYKPFSPVVEHLR
HHHCCCCCHHHHEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHH
SLRSQLMLRWFEPDTDRNVLAIVSPGLGEGRSFIAANLAIVFSQLGKSTLLIDANLRAPR
HHHHHHHEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCC
QQEFFKVNTGGGLSSYLAGRAGLESIVRIPSLLGLSVLPAGAVPPNPQELIGRPVFADLL
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHH
QSVGCEFDVVIVDTPSASEYGEAQIIATEASAALIVLRKNHTSLSRTVDLARRFQQTGAA
HHCCCCEEEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VVGSVLNDF
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7896702 [H]