Click here to switch to the map view.

The map label for this gene is lptA [H]

Identifier: 82701221

GI number: 82701221

Start: 89617

End: 90189

Strand: Reverse

Name: lptA [H]

Synonym: Nmul_A0086

Alternate gene names: 82701221

Gene position: 90189-89617 (Counterclockwise)

Preceding gene: 82701222

Following gene: 82701220

Centisome position: 2.83

GC content: 52.88

Gene sequence:

>573_bases
ATGACAAGAAACGCTAGGTTCTCTTTTACTGCTCCCATGAAACCCCTATCTGTCGCTTTTCTCGCTGTAATGCTCTTCAG
CGCACCGGTTCGGGCCGAGCGGGCCGACAGCGAGAAGCCTGTGCATCTGGAGGCCGACCGTGCCACCGTGCAGGATGCCA
ACAAGCTGGCTACCTTTATCGGCAATGTCGTACTGACACAGGGAACACTGATTATTCGCGCGGATAAGATGACAGTGAAG
GAAGACGCCAACGGTTTTCAATATGCCACTGCATTCGGCAATCTTGCCAGTTTTCGCCAGAAGCGCGATGGCAAGGATGA
ATACGTGGAGGGCTGGAGCGAGCGTATGGAATACGATGGCAAGGCCGACAAGGTTCAGCTTTTCAAGAAAGCAAGGTTGA
GGCGCGGAAAGGATGAAGTTCATGGGGATTATATTTCCTATGACGCAGTCAACGAATTCTTCCAGGTAAATGGCGAGGGT
GGAACGAGCACCCAAACCCATTCGGAGGGCAGGGTGCGAGCGGTGATACAGCCCAAAAAGAAGGAGCCCAAACCCGAGGC
AGACAATTCATAA

Upstream 100 bases:

>100_bases
GTGGAGATAACTGAAACAAACGCCACTATCAGAGCGATTGGAATGGAAATGAACAATCGTACGGGCCACACGGAATTGTT
GTCGCAGGTAAAGGTCGTGC

Downstream 100 bases:

>100_bases
ACGAACATCATTATGGAACTTCCCCTCTCTTCAGCCCGCGGCCATGCCGATCATGCTTCCCAAGCCCCCGAAGCTCCCCT
GGTTTCCTCAGGAAAGAGAA

Product: OstA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MTRNARFSFTAPMKPLSVAFLAVMLFSAPVRAERADSEKPVHLEADRATVQDANKLATFIGNVVLTQGTLIIRADKMTVK
EDANGFQYATAFGNLASFRQKRDGKDEYVEGWSERMEYDGKADKVQLFKKARLRRGKDEVHGDYISYDAVNEFFQVNGEG
GTSTQTHSEGRVRAVIQPKKKEPKPEADNS

Sequences:

>Translated_190_residues
MTRNARFSFTAPMKPLSVAFLAVMLFSAPVRAERADSEKPVHLEADRATVQDANKLATFIGNVVLTQGTLIIRADKMTVK
EDANGFQYATAFGNLASFRQKRDGKDEYVEGWSERMEYDGKADKVQLFKKARLRRGKDEVHGDYISYDAVNEFFQVNGEG
GTSTQTHSEGRVRAVIQPKKKEPKPEADNS
>Mature_189_residues
TRNARFSFTAPMKPLSVAFLAVMLFSAPVRAERADSEKPVHLEADRATVQDANKLATFIGNVVLTQGTLIIRADKMTVKE
DANGFQYATAFGNLASFRQKRDGKDEYVEGWSERMEYDGKADKVQLFKKARLRRGKDEVHGDYISYDAVNEFFQVNGEGG
TSTQTHSEGRVRAVIQPKKKEPKPEADNS

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=128, Percent_Identity=32.8125, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 21267; Mature: 21136

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRNARFSFTAPMKPLSVAFLAVMLFSAPVRAERADSEKPVHLEADRATVQDANKLATFI
CCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHCCCCCCCEEEECCHHHHHHHHHHHHHH
GNVVLTQGTLIIRADKMTVKEDANGFQYATAFGNLASFRQKRDGKDEYVEGWSERMEYDG
HHHHEECCEEEEEECCEEECCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
KADKVQLFKKARLRRGKDEVHGDYISYDAVNEFFQVNGEGGTSTQTHSEGRVRAVIQPKK
CHHHHHHHHHHHHHCCCHHHCCCEECHHHHHHHHEECCCCCCCCCCCCCCCEEEEECCCC
KEPKPEADNS
CCCCCCCCCC
>Mature Secondary Structure 
TRNARFSFTAPMKPLSVAFLAVMLFSAPVRAERADSEKPVHLEADRATVQDANKLATFI
CCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHCCCCCCCEEEECCHHHHHHHHHHHHHH
GNVVLTQGTLIIRADKMTVKEDANGFQYATAFGNLASFRQKRDGKDEYVEGWSERMEYDG
HHHHEECCEEEEEECCEEECCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
KADKVQLFKKARLRRGKDEVHGDYISYDAVNEFFQVNGEGGTSTQTHSEGRVRAVIQPKK
CHHHHHHHHHHHHHCCCHHHCCCEECHHHHHHHHEECCCCCCCCCCCCCCCEEEEECCCC
KEPKPEADNS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]