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The map label for this gene is sppA [H]

Identifier: 82701192

GI number: 82701192

Start: 63303

End: 64268

Strand: Reverse

Name: sppA [H]

Synonym: Nmul_A0057

Alternate gene names: 82701192

Gene position: 64268-63303 (Counterclockwise)

Preceding gene: 82701193

Following gene: 82701191

Centisome position: 2.02

GC content: 54.97

Gene sequence:

>966_bases
ATGAGTCTTCATACTGAACTCTTTGGCCGCCCCTGGGCATTGCACAAGGAAACTTTTGAAAGCCTGATCCGAAACGCACA
CGCTGCCGGTCCAGGCCTCAAGTTTCCGGCATCCCAACGCAAAAGTGTTTCGCAGGACGGCGTGGCAGTTATCGATATCA
CTGGCCCTATCACGCCACGCGCAAGCTTCCTCAGTCTGCTCTTTGGCGGCACAGATGTGGAAACCATCCAGCAGGACCTG
AGCGCTGCCTTGGCTGACTCGTCCGTTAACAAGATCGTATTGAACATTGATTCGCCTGGAGGCGTGGTATCCGGAGTATC
TCCGCTGGCGGACCAAATATTCTCGGCTCGATCCATCAAGCCAATAGAGTCTTTTGTTTCCGGAATGGGAGCTTCCGCTG
CTTACTGGCTGGCAGCCGCTACCAGTCACATCACAATTTCCGATACAGCTCTGGTAGGCAGCATCGGGGTGGTTGGCACA
GCCATTGATGACAAGGCGCGCCAGCAAATGCAGGGAGTCATTTTTCATCAGATCGTTTCTTCCAATGCACCCAAGAAAAG
ACCTGATCCGGCGACCCCTGAGGGGCTCCAGGTCCTGCAGAAAGAAATCGACAGTCTTGCCAGTGTATTTACCGCGAAGG
TTGCACGGTATCGCGGAGTTAATGAAATGAAGGTCAACTCCGACTTCGGGCAAGGCGGGGTATTGGTTGGCGTTGAGGCA
GTAAGGGCGGGACTGGCTGACGCCATTGGCACGTTTGAAAGTACCCTGGTTTCGTCTGGCGCAATGCCCAGCGCAGCCAG
GGCAACGAAAAAGGAGGAGCAAATATCTATGTCCCTGGAAGAATCCTGCGCTGCCCAGTGGCGCAATGATCCGCAGATTC
GTGAGGAATTCGTGACACTCGAGGGCTTCACGGCCTACACGCGCGCAGCTGCGGCAGGCAGCGTCAAGATATTACGTCGC
GTGTAA

Upstream 100 bases:

>100_bases
GTGAACTGCCGCCTTTGATTACTGACGTGCTCAGCCAGGAGCAGATCGAAAACGCGCTTAGATCAGCCGGATTGCATATG
TCTACGGATGCGAAAAGCTT

Downstream 100 bases:

>100_bases
GCGGTGGGTAAACAAACCTGAAAAGACAAAGGAATATCGATAATGTTTGATTGGTTAAAAGTAAAAAGCACTTTGGAAGA
CGCTCGTAACGAGTGCCAAA

Product: peptidase S49

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSLHTELFGRPWALHKETFESLIRNAHAAGPGLKFPASQRKSVSQDGVAVIDITGPITPRASFLSLLFGGTDVETIQQDL
SAALADSSVNKIVLNIDSPGGVVSGVSPLADQIFSARSIKPIESFVSGMGASAAYWLAAATSHITISDTALVGSIGVVGT
AIDDKARQQMQGVIFHQIVSSNAPKKRPDPATPEGLQVLQKEIDSLASVFTAKVARYRGVNEMKVNSDFGQGGVLVGVEA
VRAGLADAIGTFESTLVSSGAMPSAARATKKEEQISMSLEESCAAQWRNDPQIREEFVTLEGFTAYTRAAAAGSVKILRR
V

Sequences:

>Translated_321_residues
MSLHTELFGRPWALHKETFESLIRNAHAAGPGLKFPASQRKSVSQDGVAVIDITGPITPRASFLSLLFGGTDVETIQQDL
SAALADSSVNKIVLNIDSPGGVVSGVSPLADQIFSARSIKPIESFVSGMGASAAYWLAAATSHITISDTALVGSIGVVGT
AIDDKARQQMQGVIFHQIVSSNAPKKRPDPATPEGLQVLQKEIDSLASVFTAKVARYRGVNEMKVNSDFGQGGVLVGVEA
VRAGLADAIGTFESTLVSSGAMPSAARATKKEEQISMSLEESCAAQWRNDPQIREEFVTLEGFTAYTRAAAAGSVKILRR
V
>Mature_320_residues
SLHTELFGRPWALHKETFESLIRNAHAAGPGLKFPASQRKSVSQDGVAVIDITGPITPRASFLSLLFGGTDVETIQQDLS
AALADSSVNKIVLNIDSPGGVVSGVSPLADQIFSARSIKPIESFVSGMGASAAYWLAAATSHITISDTALVGSIGVVGTA
IDDKARQQMQGVIFHQIVSSNAPKKRPDPATPEGLQVLQKEIDSLASVFTAKVARYRGVNEMKVNSDFGQGGVLVGVEAV
RAGLADAIGTFESTLVSSGAMPSAARATKKEEQISMSLEESCAAQWRNDPQIREEFVTLEGFTAYTRAAAAGSVKILRRV

Specific function: Digestion of cleaved signal peptides. Required for efficient processing of precursors under conditions of hyper-secretion [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 33841; Mature: 33710

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHTELFGRPWALHKETFESLIRNAHAAGPGLKFPASQRKSVSQDGVAVIDITGPITPR
CCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCH
ASFLSLLFGGTDVETIQQDLSAALADSSVNKIVLNIDSPGGVVSGVSPLADQIFSARSIK
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCC
PIESFVSGMGASAAYWLAAATSHITISDTALVGSIGVVGTAIDDKARQQMQGVIFHQIVS
HHHHHHHCCCCHHHHHHHHHCCEEEEECHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHH
SNAPKKRPDPATPEGLQVLQKEIDSLASVFTAKVARYRGVNEMKVNSDFGQGGVLVGVEA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEHHH
VRAGLADAIGTFESTLVSSGAMPSAARATKKEEQISMSLEESCAAQWRNDPQIREEFVTL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EGFTAYTRAAAAGSVKILRRV
CCHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
SLHTELFGRPWALHKETFESLIRNAHAAGPGLKFPASQRKSVSQDGVAVIDITGPITPR
CCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCH
ASFLSLLFGGTDVETIQQDLSAALADSSVNKIVLNIDSPGGVVSGVSPLADQIFSARSIK
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCC
PIESFVSGMGASAAYWLAAATSHITISDTALVGSIGVVGTAIDDKARQQMQGVIFHQIVS
HHHHHHHCCCCHHHHHHHHHCCEEEEECHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHH
SNAPKKRPDPATPEGLQVLQKEIDSLASVFTAKVARYRGVNEMKVNSDFGQGGVLVGVEA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEHHH
VRAGLADAIGTFESTLVSSGAMPSAARATKKEEQISMSLEESCAAQWRNDPQIREEFVTL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EGFTAYTRAAAAGSVKILRRV
CCHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10455123 [H]