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The map label for this gene is prmA [H]

Identifier: 162139860

GI number: 162139860

Start: 3153574

End: 3154488

Strand: Reverse

Name: prmA [H]

Synonym: Nmul_A2751

Alternate gene names: 162139860

Gene position: 3154488-3153574 (Counterclockwise)

Preceding gene: 82703865

Following gene: 82703863

Centisome position: 99.07

GC content: 55.74

Gene sequence:

>915_bases
ATGCCCTGGATTTCAGTCATCATAAAAACGGACAGCATGCATGTCGAGATCTTAAGCGATGCGATGCTGGCTTTGGGCGC
GCTGTCAACCGACATCCATGATTCCGCAGCGGGAACCGAGCATGAGCAACCCTTGTTTGGCGAACCAGGAGAGCCCGCCG
CAGGAGTCTGGCTTGCTCCGGAGCTGACTGCGCTATTCAAGGGGGATACCGATATTCCCGCAGTAATGCGCGCTGCGGCC
GAAGCGGCGGCGTTGCCTGCTCCCCCGAGCTATCGTATCGAATATGTGGAAGAACAGGATTGGGTACGGGTAACCCAGTC
GCAGTTCAATCCGATCCGCATATCCTCCCGCTTGTGGGTCGTGCCAAGCTGGCATGAAATACCTGATCCGAATGCCATCA
ACCTGATCCTCGATCCGGGACTCGCCTTTGGAACCGGAACTCATCCTTCTACGCAGTTGTGCCTGGAATGGCTTGACGAA
AATCTCGGAGGAGGCGAAGATGTTCTTGATTACGGTTGTGGTTCAGGCATATTGGCCATTGCCGCGCTCAAGATGGGCGC
TCATCATGTTGTCGGCATCGACATAGATCCGCAAGCGGTGGAGGCAAGCTGCCAGAATGCAAGGCTTAACCAGTGCTCGG
AAACCGAAATAGAGTTTCATACACAGATGGCGGAGCGGACGGATACAGAACGCGGGGGCTGGGCGAACATCGTTGTTGCC
AATATCCTCGCCAATCCGCTGATCATGCTGGCTCCCATACTGACGCATGCTGCCCGGCCGGGAGGACGCATTGCCCTATC
CGGTATACTCGCGGAACAGGCAGAAGAAGTGATGGCGGCCTATCAGCAATCGTTTGATATGCATATTGCGCTAAATCGTG
AGGGATGGGTCCTGTTGACAGGCGCGAGGAAGTGA

Upstream 100 bases:

>100_bases
GGGTAACGGACGGGGGTGAGGTAGGAGCCTCTCGGGAAACGGGCCTGGAATGTTCTGCCCGCCGTCTGCTTACGCAGCCA
AATGCAAGGGACGTACCCTC

Downstream 100 bases:

>100_bases
ATTCGATTAAACAAAAACCAGAACCGGAATGCCACTTGTAACTCGATGTCCTAACTGCTTAACGGTCTTTCGCATCACGC
CTCTGCACTTGCAGGCGCAT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MPWISVIIKTDSMHVEILSDAMLALGALSTDIHDSAAGTEHEQPLFGEPGEPAAGVWLAPELTALFKGDTDIPAVMRAAA
EAAALPAPPSYRIEYVEEQDWVRVTQSQFNPIRISSRLWVVPSWHEIPDPNAINLILDPGLAFGTGTHPSTQLCLEWLDE
NLGGGEDVLDYGCGSGILAIAALKMGAHHVVGIDIDPQAVEASCQNARLNQCSETEIEFHTQMAERTDTERGGWANIVVA
NILANPLIMLAPILTHAARPGGRIALSGILAEQAEEVMAAYQQSFDMHIALNREGWVLLTGARK

Sequences:

>Translated_304_residues
MPWISVIIKTDSMHVEILSDAMLALGALSTDIHDSAAGTEHEQPLFGEPGEPAAGVWLAPELTALFKGDTDIPAVMRAAA
EAAALPAPPSYRIEYVEEQDWVRVTQSQFNPIRISSRLWVVPSWHEIPDPNAINLILDPGLAFGTGTHPSTQLCLEWLDE
NLGGGEDVLDYGCGSGILAIAALKMGAHHVVGIDIDPQAVEASCQNARLNQCSETEIEFHTQMAERTDTERGGWANIVVA
NILANPLIMLAPILTHAARPGGRIALSGILAEQAEEVMAAYQQSFDMHIALNREGWVLLTGARK
>Mature_303_residues
PWISVIIKTDSMHVEILSDAMLALGALSTDIHDSAAGTEHEQPLFGEPGEPAAGVWLAPELTALFKGDTDIPAVMRAAAE
AAALPAPPSYRIEYVEEQDWVRVTQSQFNPIRISSRLWVVPSWHEIPDPNAINLILDPGLAFGTGTHPSTQLCLEWLDEN
LGGGEDVLDYGCGSGILAIAALKMGAHHVVGIDIDPQAVEASCQNARLNQCSETEIEFHTQMAERTDTERGGWANIVVAN
ILANPLIMLAPILTHAARPGGRIALSGILAEQAEEVMAAYQQSFDMHIALNREGWVLLTGARK

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=304, Percent_Identity=43.75, Blast_Score=215, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32778; Mature: 32646

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWISVIIKTDSMHVEILSDAMLALGALSTDIHDSAAGTEHEQPLFGEPGEPAAGVWLAP
CCCEEEEEECCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
ELTALFKGDTDIPAVMRAAAEAAALPAPPSYRIEYVEEQDWVRVTQSQFNPIRISSRLWV
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHCCCEEEECCEEEE
VPSWHEIPDPNAINLILDPGLAFGTGTHPSTQLCLEWLDENLGGGEDVLDYGCGSGILAI
EECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHH
AALKMGAHHVVGIDIDPQAVEASCQNARLNQCSETEIEFHTQMAERTDTERGGWANIVVA
HHHHCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
NILANPLIMLAPILTHAARPGGRIALSGILAEQAEEVMAAYQQSFDMHIALNREGWVLLT
HHHHCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEE
GARK
CCCC
>Mature Secondary Structure 
PWISVIIKTDSMHVEILSDAMLALGALSTDIHDSAAGTEHEQPLFGEPGEPAAGVWLAP
CCEEEEEECCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
ELTALFKGDTDIPAVMRAAAEAAALPAPPSYRIEYVEEQDWVRVTQSQFNPIRISSRLWV
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHCCCEEEECCEEEE
VPSWHEIPDPNAINLILDPGLAFGTGTHPSTQLCLEWLDENLGGGEDVLDYGCGSGILAI
EECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHH
AALKMGAHHVVGIDIDPQAVEASCQNARLNQCSETEIEFHTQMAERTDTERGGWANIVVA
HHHHCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
NILANPLIMLAPILTHAARPGGRIALSGILAEQAEEVMAAYQQSFDMHIALNREGWVLLT
HHHHCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEE
GARK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]