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The map label for this gene is treC [H]

Identifier: 82546514

GI number: 82546514

Start: 4257690

End: 4259345

Strand: Direct

Name: treC [H]

Synonym: SBO_4207

Alternate gene names: 82546514

Gene position: 4257690-4259345 (Clockwise)

Preceding gene: 82546513

Following gene: 82546515

Centisome position: 94.2

GC content: 52.96

Gene sequence:

>1656_bases
ATGACTAATCCTCCCCACTGGTGGCAAAACGGCGTTATCTACCAGATTTATCCAAAGAGTTTTCAGGACACCACGGGTAG
CGGTACCGGCGATTTACGTGGCGTTATCCAACGCCTGGACTATCTGCATAAACTGGGCGTTGATGCCATCTGGCTAACCC
CCTTTTATGTCTCTCCCCAGGTCGATAACGGTTACGACGTAGCGAACTATACGGCGATTGATCCCACCTACGGCACGCTG
GACGATTTTGACGAACTGGTGACGCAGGCAAAATCGCGCGGGATTCGTATCATTCTCGATATGGTGTTTAACCATACCTC
TACCCAACATGCCTGGTTTCGCGAGGCGCTGAACAAAGAAAGCCCTTACCGCCAGTTTTATATCTGGCGCGATGGAGAAC
CAGAAACGCCACCGAACAACTGGCGTTCAAAATTTGGCGGTAGTGCGTGGCGCTGGCATGCGGAAAGCGAACAGTACTAT
TTGCATCTCTTTGCACCAGAACAGGCGGATCTCAACTGGGAGAATCCAGCGGTACGCGCAGTGCTGAAAAAAGTCTGTGA
GTTCTGGGCCGATCGTGGGGTCGACGGGTTGCGCCTGGATGTGGTGAATCTGATCTCCAAAGACCCGCGTTTCCCTGATG
ACCTGGATGGCGACGGGCGTCGCTTCTACACCGACGGGCCACGAGCACACGAGTTTTTGCACGAGATGAACCGCGATGTG
TTTACGCCACGCGGGTTAATGACCGTAGGTGAAATGTCCTCCACCAGCCTTGAGCATTGCCAGCGATACGCGGCACTGAC
AGGCAGTGAATTGTCGATGACCTTTAATTTTCATCACCTGAAGGTCGATTATCCCGGTGGTGAAAAATGGACGCTGGCTA
AACCTGACTTTGTGGCGTTGAAAACATTGTTCCGCCACTGGCAACAAGGAATGCACAACGTAGCATGGAATGCCTTGTTC
TGGTGTAACCACGATCAGCCGCGCATTGTTTCTCGCTTTGGTGATGAAGGTGAATACCGCGTGCCTGCGGCAAAAATGCT
GGCGATGGTGCTGCATGGCATGCAGGGAACGCCGTATATCTACCAGGGCGAAGAGATTGGCATGACCAACCCGCATTTCA
CGCGCATTACTGACTATCGCGACGTAGAGAGCCTCAATATGTTTGCCGAGCTGCGCAACGATGGTCGTGATGCCGACGAG
TTATTGGCAATCCTCGCCAGTAAATCCCGTGACAACAGCCGCACGCCCATGCAATGGAGCAACGGCGATAATGCCGGATT
TACGGCTGGCGAACCGTGGATTGGCCTGGGTGATAACTATCAACAAATCAACGTAGAAGCCGCGCTGGCCGATGATTCCT
CGGTGTTTTACACCTACCAAAAGTTAATCGCACTGCGTAAGCAGGAAGCCATCCTGACATGGGGCAATTACCAGGATCTG
CTGCCAAACAGCCCTGTATTGTGGTGCTATCGCCGTGAATGGAAGGGGCAAACCTTGCTGGTCATTGCCAACCTTAGCCG
TGAGATCCAACCCTGGCAGCCAGGGCAAATGCGCGGCAACTGGCAGCTTGTGATGCATAACTACGAAGAAGCCTCACCAC
AACCCTGTGCCATGAATTTACGGCCTTTTGAGGCTGTCTGGTGGTTACAGAAGTAA

Upstream 100 bases:

>100_bases
TCGTTTATCTATCAGCGGAAATACCGCCTGGGCACGCTGGACATTGTTTAATTTTCTTCGGGGCGCAATTGCGCCCCCTC
GCATTTGCAGGAATAACGTA

Downstream 100 bases:

>100_bases
ATCTTCCCTAAGCCCCGGTAATGCCGGTCATTCCGGGGTTTTGTCTGTCAGCATGTTGTTTTTGTTTATTTTTCAACCAG
CAAATTCATTAAAAAATTTA

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MTNPPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTL
DDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
LHLFAPEQADLNWENPAVRAVLKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDV
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALF
WCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADE
LLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALADDSSVFYTYQKLIALRKQEAILTWGNYQDL
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMNLRPFEAVWWLQK

Sequences:

>Translated_551_residues
MTNPPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTL
DDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
LHLFAPEQADLNWENPAVRAVLKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDV
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALF
WCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADE
LLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALADDSSVFYTYQKLIALRKQEAILTWGNYQDL
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMNLRPFEAVWWLQK
>Mature_550_residues
TNPPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLD
DFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYYL
HLFAPEQADLNWENPAVRAVLKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDVF
TPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFW
CNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADEL
LAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALADDSSVFYTYQKLIALRKQEAILTWGNYQDLL
PNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMNLRPFEAVWWLQK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=522, Percent_Identity=29.5019157088123, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI65506891, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI61744479, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI61744475, Length=107, Percent_Identity=36.4485981308411, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI61744481, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI61744483, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI61744477, Length=107, Percent_Identity=36.4485981308411, Blast_Score=73, Evalue=8e-13,
Organism=Escherichia coli, GI1790687, Length=551, Percent_Identity=98.9110707803993, Blast_Score=1140, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=110, Percent_Identity=38.1818181818182, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1789995, Length=137, Percent_Identity=32.8467153284672, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=483, Percent_Identity=26.5010351966874, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32565753, Length=526, Percent_Identity=22.4334600760456, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321726, Length=576, Percent_Identity=36.2847222222222, Blast_Score=358, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6322245, Length=578, Percent_Identity=36.5051903114187, Blast_Score=357, Evalue=3e-99,
Organism=Saccharomyces cerevisiae, GI6324416, Length=576, Percent_Identity=36.6319444444444, Blast_Score=345, Evalue=9e-96,
Organism=Saccharomyces cerevisiae, GI6322241, Length=576, Percent_Identity=36.6319444444444, Blast_Score=345, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6322021, Length=576, Percent_Identity=36.6319444444444, Blast_Score=345, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6321731, Length=586, Percent_Identity=34.9829351535836, Blast_Score=334, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6319776, Length=586, Percent_Identity=34.8122866894198, Blast_Score=333, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24583745, Length=537, Percent_Identity=36.1266294227188, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24583747, Length=545, Percent_Identity=35.7798165137615, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24583749, Length=545, Percent_Identity=35.7798165137615, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI221330053, Length=499, Percent_Identity=37.2745490981964, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24586599, Length=578, Percent_Identity=32.1799307958478, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24586597, Length=532, Percent_Identity=34.2105263157895, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24586587, Length=503, Percent_Identity=33.5984095427435, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24586593, Length=520, Percent_Identity=32.5, Blast_Score=268, Evalue=9e-72,
Organism=Drosophila melanogaster, GI45549022, Length=541, Percent_Identity=33.641404805915, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24586589, Length=539, Percent_Identity=33.0241187384045, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI24586591, Length=494, Percent_Identity=32.9959514170041, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI281360393, Length=466, Percent_Identity=30.2575107296137, Blast_Score=200, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63800; Mature: 63669

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQ
CCCCCCCHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKE
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCHHHHHHHHHCCC
SPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYYLHLFAPEQADLNWENPAVRA
CCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCCCCCHHHHH
VLKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDV
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCC
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVAL
CCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCEEEECCCCHHHH
KTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYI
HHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADELLAILASKSRDNSRTPMQWS
EECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEC
NGDNAGFTAGEPWIGLGDNYQQINVEAALADDSSVFYTYQKLIALRKQEAILTWGNYQDL
CCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCHHH
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMNL
CCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
RPFEAVWWLQK
CCCCCEEEECC
>Mature Secondary Structure 
TNPPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQ
CCCCCCHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKE
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCHHHHHHHHHCCC
SPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYYLHLFAPEQADLNWENPAVRA
CCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCCCCCHHHHH
VLKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDV
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCC
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVAL
CCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCEEEECCCCHHHH
KTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYI
HHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADELLAILASKSRDNSRTPMQWS
EECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEC
NGDNAGFTAGEPWIGLGDNYQQINVEAALADDSSVFYTYQKLIALRKQEAILTWGNYQDL
CCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCHHH
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMNL
CCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
RPFEAVWWLQK
CCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083158; 7610040; 9278503; 8421692 [H]