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The map label for this gene is yadA [H]

Identifier: 82545969

GI number: 82545969

Start: 3623570

End: 3624409

Strand: Direct

Name: yadA [H]

Synonym: SBO_3607

Alternate gene names: 82545969

Gene position: 3623570-3624409 (Clockwise)

Preceding gene: 161984831

Following gene: 82545970

Centisome position: 80.17

GC content: 50.83

Gene sequence:

>840_bases
GTGATAACAGATGTCTGGAAATATAGGGGCAAATCCACCCAGAGCATTACTAACCTGAACAATCAGGTCACTAATCTGGA
TACTCGCGTTACTAATATCGAAAACGGTATTGGCGACATTGTCACCACCGGTAGCACCAAGTACTTCAAGACCAACACCG
ATGGCGTAGATGCCAACGCCCAGGGTAAAGATAGCGTTGCTATTGGTTCTGGTTCCATTGCTGCCGCTGACAACAGCGTC
GCACTGGGTACCGGTTCCGTTGCAGAGGAAGAAAATACAATCTCTGTAGGTTCTTCTACTAACCAACGCCGTATCACCAA
CGTAGCTGCCGGTGTTAATGCCACCGATGCGGTTAACGTGTCGCAGCTGAAATCTTCTGAAGCAGGCGGCGTGCGCTACG
ACACCAAAGCTGATGGTTCTATCGACTATAGCAATATCACCCTCGGTGGTGGCAACGGCAGTACGACTCGTATCAGCAAC
GTCTCCGCTGGCGTCAACAACAACGACGCGGTGAACTACGCGCAGTTGAAGCAAAGCGTGCAGGAAACGAAGCAATACAC
CGATCAGCGGATGGTTGAGATGGATAACAAACTGTCTAAAACTGAAAGCAAGTTGAGCGGTGGTATCGCTTCTGCAATGG
CAATGACCGGTCTGCCGCAGGCTTATACACCGGGTGCCAGCATGGCTTCTATTGGTGGCGGTACTTACAACGGTGAATCG
GCAGTTGCTTTAGGTGTATCGATGGTGAGCGCCAATGGTCGTTGGGTCTACAAATTACAAGGTAGTACCAATAGCCAGGG
TGAATACTCCGCCGCACTCGGTGCCGGTATTCAGTGGTAA

Upstream 100 bases:

>100_bases
GCAGAGGCGTTCGAGCATTATAACGAATGGCATCCGCATAGTGCGCTGGGTTATCGCTCGCCACGGGAATATCTGCGGCA
GCGGGCTTGTAATGGGTTAA

Downstream 100 bases:

>100_bases
TGATCCATTAAGTTAGTGTGACTAAGGGCAAACGCCAAATTGCCTGATGCGTTACGCGCATCAGGCAAGATAAGGCGCTC
CGGGTCAACAATCTAAGGGC

Product: adhesin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MITDVWKYRGKSTQSITNLNNQVTNLDTRVTNIENGIGDIVTTGSTKYFKTNTDGVDANAQGKDSVAIGSGSIAAADNSV
ALGTGSVAEEENTISVGSSTNQRRITNVAAGVNATDAVNVSQLKSSEAGGVRYDTKADGSIDYSNITLGGGNGSTTRISN
VSAGVNNNDAVNYAQLKQSVQETKQYTDQRMVEMDNKLSKTESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGES
AVALGVSMVSANGRWVYKLQGSTNSQGEYSAALGAGIQW

Sequences:

>Translated_279_residues
MITDVWKYRGKSTQSITNLNNQVTNLDTRVTNIENGIGDIVTTGSTKYFKTNTDGVDANAQGKDSVAIGSGSIAAADNSV
ALGTGSVAEEENTISVGSSTNQRRITNVAAGVNATDAVNVSQLKSSEAGGVRYDTKADGSIDYSNITLGGGNGSTTRISN
VSAGVNNNDAVNYAQLKQSVQETKQYTDQRMVEMDNKLSKTESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGES
AVALGVSMVSANGRWVYKLQGSTNSQGEYSAALGAGIQW
>Mature_279_residues
MITDVWKYRGKSTQSITNLNNQVTNLDTRVTNIENGIGDIVTTGSTKYFKTNTDGVDANAQGKDSVAIGSGSIAAADNSV
ALGTGSVAEEENTISVGSSTNQRRITNVAAGVNATDAVNVSQLKSSEAGGVRYDTKADGSIDYSNITLGGGNGSTTRISN
VSAGVNNNDAVNYAQLKQSVQETKQYTDQRMVEMDNKLSKTESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGES
AVALGVSMVSANGRWVYKLQGSTNSQGEYSAALGAGIQW

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes attachment to eukaryotic cells and after invasion, is the major adhesin in infected tissue. Constitutes an alternative uptake pathway under conditio

COG id: COG5295

COG function: function code UW; Autotransporter adhesin

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 28786; Mature: 28786

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDVWKYRGKSTQSITNLNNQVTNLDTRVTNIENGIGDIVTTGSTKYFKTNTDGVDANA
CCCCCHHHCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCCCCCCCC
QGKDSVAIGSGSIAAADNSVALGTGSVAEEENTISVGSSTNQRRITNVAAGVNATDAVNV
CCCCCEEECCCCEEECCCCEEECCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCCH
SQLKSSEAGGVRYDTKADGSIDYSNITLGGGNGSTTRISNVSAGVNNNDAVNYAQLKQSV
HHHCCCCCCCEEECCCCCCCEEECEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
QETKQYTDQRMVEMDNKLSKTESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGES
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCC
AVALGVSMVSANGRWVYKLQGSTNSQGEYSAALGAGIQW
EEEEEEEEEECCCEEEEEECCCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure
MITDVWKYRGKSTQSITNLNNQVTNLDTRVTNIENGIGDIVTTGSTKYFKTNTDGVDANA
CCCCCHHHCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCCCCCCCC
QGKDSVAIGSGSIAAADNSVALGTGSVAEEENTISVGSSTNQRRITNVAAGVNATDAVNV
CCCCCEEECCCCEEECCCCEEECCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCCH
SQLKSSEAGGVRYDTKADGSIDYSNITLGGGNGSTTRISNVSAGVNNNDAVNYAQLKQSV
HHHCCCCCCCEEECCCCCCCEEECEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
QETKQYTDQRMVEMDNKLSKTESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGES
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCC
AVALGVSMVSANGRWVYKLQGSTNSQGEYSAALGAGIQW
EEEEEEEEEECCCEEEEEECCCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3043229; 2761389; 2592347; 1548243; 12183532 [H]