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The map label for this gene is yghZ [H]

Identifier: 82545386

GI number: 82545386

Start: 2998859

End: 2999899

Strand: Direct

Name: yghZ [H]

Synonym: SBO_2995

Alternate gene names: 82545386

Gene position: 2998859-2999899 (Clockwise)

Preceding gene: 82545381

Following gene: 82545388

Centisome position: 66.35

GC content: 51.97

Gene sequence:

>1041_bases
ATGGTCTGGTTAGCGAATCCCGCACGTTACGGGCAGATGCAGTACCGCTATTGCGGAAAAAGTGGTTTACGCCTGCCCGC
GTTATCGCTCGGTTTATGGCACAATTTCGGTCACGTTAACGCGCTGGAATCACAGCGTGCAATCCTGCGTAAAGCGTTTG
ATTTAGGCATTACGCACTTTGATTTAGCCAACAATTACGGGCCGCCTCCAGGAAGCGCAGAAGAGAACTTTGGTCGCCTG
CTGCGGGAGGATTTTGCCGCTTATCGCGATGAACTGATTATCTCTACCAAGGCTGGCTACGATATGTGGCCCGGCCCTTA
CGGCTCTGGCGGTTCACGTAAATACCTGCTCGCCAGCCTCGACCAAAGCCTGAAGCGTATGGGGCTTGAGTATGTCGATA
TCTTTTACTCTCATCGCGTCGATGAAAATACGCCGATGGAAGAAACCGCCTCTGCGCTGGCTCATGCGGTACAAAGCGGT
AAGGCGCTGTATGTCGGGATCTCCTCTTACTCGCCAGAGCGGACGCAAAAAATGGTCGAGTTGCTGCACGAGTGGAAAAT
TCCGCTTTTAATTCATCAACCTTCGTACAATTTACTGAACCGCTGGGTGGATAAAAGCGGCCTGCTGGATACCCTGCAAA
ATAACGGCGTGGGCTGTATTGCCTTTACTCCTCTGGCTCAGGGATTGCTGACCGGAAAATATCTCAACGGCATTCCGCAA
GATTCACGGATGCATCGTGAAGGGAATAAAGTTCGTGGTCTGACGCCGAAAATGCTTACCGAAGCCAACCTCAACAGCCT
GCGCTTATTGAATGAAATGGCACAGCAGCGTGGACAATCAATGGCGCAAATGGCGTTAAGCTGGTTGCTGAAAGATGATC
GCGTGACGTCGGTATTGATTGGTGTCAGCCGCGCGGAGCAACTAGAGGAGAACGTGCAGGCGCTGAATAATCTGACATTT
AGCACCGAGGAGCTGGCGCAGATTGATCAGCATATCGCCGATGGCGAGCTGAATCTGTGGCAGGCGTCTTCCGATAAATG
A

Upstream 100 bases:

>100_bases
CAGTTTTTCGTCACTCTGTGAGCCAGACTACGGGATACGCGCTGGCGAATCGCTAAACTAGAAACATTGTTTCGAAATTG
AACGGTGGAAAGGAGAGGTC

Downstream 100 bases:

>100_bases
CCTGTTAATAACGGGCGCGCGAACCGCGCCCGAATCAGATCAGTGATTATGACGAGTCAGTCGGTCAAGATAGCCCATCA
CAAATGCAGAGAGCACAAAC

Product: aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MVWLANPARYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSVLIGVSRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Sequences:

>Translated_346_residues
MVWLANPARYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSVLIGVSRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK
>Mature_346_residues
MVWLANPARYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSVLIGVSRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4504825, Length=339, Percent_Identity=34.8082595870207, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=34.6504559270517, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI27436964, Length=329, Percent_Identity=34.0425531914894, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=34.2592592592593, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=33.9506172839506, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI27436971, Length=326, Percent_Identity=33.7423312883436, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI41152114, Length=211, Percent_Identity=31.7535545023697, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI41327764, Length=213, Percent_Identity=30.5164319248826, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI223718702, Length=286, Percent_Identity=28.6713286713287, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789375, Length=346, Percent_Identity=98.8439306358381, Blast_Score=707, Evalue=0.0,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=36.0606060606061, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=26.4150943396226, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788081, Length=323, Percent_Identity=23.8390092879257, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=23.1454005934718, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323998, Length=315, Percent_Identity=24.7619047619048, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319958, Length=238, Percent_Identity=24.7899159663866, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322615, Length=238, Percent_Identity=24.3697478991597, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=27.8260869565217, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=27.8260869565217, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24646159, Length=328, Percent_Identity=25.609756097561, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646155, Length=328, Percent_Identity=26.219512195122, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38785; Mature: 38785

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWLANPARYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHF
CEECCCCHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
LLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSVLI
CHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GVSRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure
MVWLANPARYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHF
CEECCCCHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
LLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSVLI
CHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GVSRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]