BacMap

Definition	Shigella boydii Sb227, complete genome.
Accession	NC_007613
Length	4,519,823

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The map label for this gene is gudP [H]

Identifier: 82545088

GI number: 82545088

Start: 2677461

End: 2678768

Strand: Reverse

Name: gudP [H]

Synonym: SBO_2670

Alternate gene names: 82545088

Gene position: 2678768-2677461 (Counterclockwise)

Preceding gene: 82545089

Following gene: 82545087

Centisome position: 59.27

GC content: 52.37

Gene sequence:

>1308_bases
GTGGAAAAACGCACGAATGCTCGTTACTGGATAGTGGTGATGTTGTTTATCGTCACATCCTTCAACTACGGCGACCGCGC
TACGCTTTCTATTGCCGGTTCGGAAATGGCCAAAGATATCGGCCTTGATCCCGTGGGAATGGGCTATGTGTTCTCTGCCT
TCTCATGGGCTTATGTTATCGGGCAGATCCCTGGTGGTTGGTTGCTGGATCGTTTTGGTTCAAAACGCGTCTACTTCTGG
TCGATGTTTACCTTGCTGCAAGGCTTCGTCGATATCTTTAGTGGATTCGGCATTATCGTTGCCCTGTTTACTCTGCGCTT
CCTGGTCGGGCTTGCTGAAGCGCCATCTTTCCCCGGCAACAGTCGCATTGTTGCGGCTTGGTTTCCGGCGCAGGAAAGGG
GAACGGCGGTGTCGATTTTTAACTCCGCTCAATACTTCGCAACGGTGATCTTCGCGCCGATTATGGGCTGGCTGACGCAT
GAAGTGGGCTGGTCACACGTCTTCTTCTTTATGGGCGGTCTGGGGATTGTCATCAGCTTTATCTGGTTGAAAGTCATCCA
CGAGCCAAATCAACATCCGGGGGTAAATCAGAAAGAGCTGGAGTACATCGCCGCGGGTGGCGCGCTGATCAATATGGATC
AGCAAAACACCAAAGTTAAAGTGCCGTTCAGCGTGAAGTGGGGGCAGATCAAACAACTGCTCGGGTCACGGATGATGATC
GGCGTTTATATCGGTCAGTACTGTATCAACGCCCTGACTTACTTTTTCATTACCTGGTTTCCGGTTTATCTGGTGCAGGC
GCGTGGGATGTCAATTCTGAAAGCGGGCTTTGTGGCTTCCGTTCCGGCGGTTTGCGGTTTTATCGGCGGTGTGCTGGGTG
GGATTATTTCCGACTGGCTGATGCGCCGCACGGGATCGCTGAACATTGCGCGTAAAACACCGATCGTAATGGGCATGTTG
CTGTCGATGGTGATGGTGTTCTGCAACTACGTCAACGTTGAGTGGATGATCATCGGCTTTATGGCGCTGGCCTTCTTCGG
TAAGGGCATCGGGGCGCTGGGTTGGGCAGTAATGGCAGATACCGCGCCAAAAGAGATCAGCGGTCTTTCCGGTGGCCTGT
TCAACATGTTCGGTAACATTTCTGGCATCGTCACGCCAATCGCAATTGGTTATATCGTTGGCACGACTGGCTCCTTTAAT
GGGGCGCTGATTTATGTTGGTGTTCATGCCTTAATCGCGGTACTGAGCTACCTGGTGCTGGTGGGCGATATCAAGCGTAT
CGAGCTGAAACCTGTCGCGGGGCAATAA

Upstream 100 bases:

>100_bases
ACCTCTGATTTCCTGGCTATGTCGCAGTCCAGAGTTAGCGTGGCTAACGCGAATTTTCAGGAGTGCAACAACGAGTTCTT
TAAGTCAGGCTGCGAGCAGT

Downstream 100 bases:

>100_bases
GATGACGACACAATCCAGTCCTGTTATTACTGATATGAAAGTCATTCCGGTCGCCGGGCACGATAGCATGTTGCTTAATA
TTGGTGGGGCACATAACGCA

Product: transport protein

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFW
SMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTH
EVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMI
GVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGML
LSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFN
GALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ

Sequences:

>Translated_435_residues
MEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFW
SMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTH
EVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMI
GVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGML
LSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFN
GALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ
>Mature_435_residues
MEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFW
SMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTH
EVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMI
GVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGML
LSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFN
GALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=409, Percent_Identity=27.1393643031785, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI9945322, Length=409, Percent_Identity=27.6283618581907, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI21322234, Length=410, Percent_Identity=25.8536585365854, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI148743791, Length=392, Percent_Identity=25, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI6912666, Length=368, Percent_Identity=25.5434782608696, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4885441, Length=376, Percent_Identity=25.2659574468085, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI5031955, Length=266, Percent_Identity=25.5639097744361, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI256219598, Length=374, Percent_Identity=23.7967914438503, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4503847, Length=374, Percent_Identity=23.7967914438503, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI256219483, Length=374, Percent_Identity=23.7967914438503, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI148728191, Length=306, Percent_Identity=24.8366013071895, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI154350196, Length=421, Percent_Identity=23.2779097387173, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI223718438, Length=215, Percent_Identity=27.906976744186, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI256219543, Length=290, Percent_Identity=25.5172413793103, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI256219564, Length=309, Percent_Identity=22.9773462783171, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI154800443, Length=289, Percent_Identity=23.5294117647059, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789152, Length=440, Percent_Identity=98.4090909090909, Blast_Score=862, Evalue=0.0,
Organism=Escherichia coli, GI1789515, Length=434, Percent_Identity=57.3732718894009, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI87082320, Length=432, Percent_Identity=42.1296296296296, Blast_Score=348, Evalue=6e-97,
Organism=Escherichia coli, GI2367379, Length=419, Percent_Identity=28.8782816229117, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI2367193, Length=434, Percent_Identity=23.963133640553, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788573, Length=441, Percent_Identity=23.3560090702948, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115533554, Length=431, Percent_Identity=27.3781902552204, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI115533556, Length=433, Percent_Identity=28.175519630485, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17552542, Length=414, Percent_Identity=24.6376811594203, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71991453, Length=370, Percent_Identity=23.2432432432432, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71991448, Length=370, Percent_Identity=23.2432432432432, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17535049, Length=433, Percent_Identity=22.4018475750577, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17560030, Length=397, Percent_Identity=24.1813602015113, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17569727, Length=380, Percent_Identity=23.9473684210526, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32565916, Length=254, Percent_Identity=24.4094488188976, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32565914, Length=360, Percent_Identity=23.0555555555556, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193205400, Length=302, Percent_Identity=22.5165562913907, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17532009, Length=409, Percent_Identity=22.2493887530562, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71997452, Length=315, Percent_Identity=20.6349206349206, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25145964, Length=288, Percent_Identity=23.2638888888889, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554148, Length=355, Percent_Identity=23.6619718309859, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71989129, Length=258, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17509575, Length=255, Percent_Identity=25.8823529411765, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534558, Length=248, Percent_Identity=25.4032258064516, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550460, Length=416, Percent_Identity=25.9615384615385, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24641682, Length=379, Percent_Identity=25.3298153034301, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24655255, Length=361, Percent_Identity=27.1468144044321, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24639764, Length=425, Percent_Identity=22.8235294117647, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24583789, Length=405, Percent_Identity=25.4320987654321, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI20130167, Length=422, Percent_Identity=27.0142180094787, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19922400, Length=429, Percent_Identity=24.009324009324, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24654215, Length=429, Percent_Identity=24.009324009324, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24655271, Length=407, Percent_Identity=25.0614250614251, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20130135, Length=407, Percent_Identity=25.0614250614251, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24648416, Length=461, Percent_Identity=24.0780911062907, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356189, Length=461, Percent_Identity=24.0780911062907, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24584153, Length=399, Percent_Identity=24.812030075188, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI62484226, Length=398, Percent_Identity=25.1256281407035, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28573299, Length=406, Percent_Identity=24.6305418719212, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI28573708, Length=430, Percent_Identity=22.093023255814, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28573707, Length=430, Percent_Identity=22.093023255814, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24580790, Length=389, Percent_Identity=23.6503856041131, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI20129235, Length=375, Percent_Identity=27.2, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24658674, Length=356, Percent_Identity=25, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24658666, Length=404, Percent_Identity=23.019801980198, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550495, Length=360, Percent_Identity=23.0555555555556, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24653727, Length=367, Percent_Identity=23.433242506812, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221474708, Length=161, Percent_Identity=32.2981366459627, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24658658, Length=406, Percent_Identity=22.1674876847291, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281361682, Length=362, Percent_Identity=22.0994475138122, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550364, Length=417, Percent_Identity=23.021582733813, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47578; Mature: 47578

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVI
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHH
GQIPGGWLLDRFGSKRVYFWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGN
HCCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISF
CEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMI
HHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCEEEEEEECCHHHHHHHHCCHHHH
GVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRRTGSLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMAD
HHHCCCCEEHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHCC
TAPKEISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVL
CCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHHEECCCCCCCEEEEHHHHHHHHHHHHHHH
VGDIKRIELKPVAGQ
HCCCCEEEEECCCCC
>Mature Secondary Structure
MEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVI
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHH
GQIPGGWLLDRFGSKRVYFWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGN
HCCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISF
CEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMI
HHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCEEEEEEECCHHHHHHHHCCHHHH
GVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRRTGSLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMAD
HHHCCCCEEHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHCC
TAPKEISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVL
CCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHHEECCCCCCCEEEEHHHHHHHHHHHHHHH
VGDIKRIELKPVAGQ
HCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9772162; 10762278 [H]