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The map label for this gene is yeiQ [H]

Identifier: 82544609

GI number: 82544609

Start: 2127305

End: 2128771

Strand: Reverse

Name: yeiQ [H]

Synonym: SBO_2152

Alternate gene names: 82544609

Gene position: 2128771-2127305 (Counterclockwise)

Preceding gene: 161984913

Following gene: 82544608

Centisome position: 47.1

GC content: 51.33

Gene sequence:

>1467_bases
ATGAAGACAATTGCCTCCGTTACGCTCCCGCATCATGTACACGCTCCACGCTACGATCGCCAGCAGTTGCAATCACGTAT
CGTTCATTTTGGCTTTGGCGCCTTTCACCGCGCTCATCAGGCGTTACTGACCGATCGTGTGCTGAATGCCCAGGGCGGCG
ACTGGGGGATCTGTGAAATCAGCTTGTTCAGCGGTGATCAACTGATGAGCCAGCTCCGCGCACAGAACCATTTATATACC
GTGCTGGAGAAAGGTGCGGACGGCAATCAGGTGATAATTGTCGGTGCCGTTCACGAATGCCTTAATGCAAAACTGGATTC
CTTAGCGGCAATTATTGAGAAATTTTGCGAGCCACAGGTGGCAATTGTTTCCCTGACGATTACCGAAAAAGGCTATTGTA
TTGACCCGGCCACCGGTGCACTCGACACCAGTAATCCGCGGATTATTCACGATCTACAAACCCCTGAAGAACCTCACTCC
GCACCGGGTATTCTCGTCGAAGCACTGAAACGCCGCCGTGAGCGCAGCCTTACACCGTTTACCGTGCTCTCCTGCGACAA
TATTCCCGACAATGGCCATGTGGTGAAAAACGCGGTGCTGAGAATGGCAGAAAAACGTTCGCCAGAACTCGCCGGGTGGA
TAAAAGAACACGTCAGTTTTCCGGGAACCATGGTCGACCGCATTGTTCCGGCTGCAACCGACGAATCACTGGCAGAAATC
AGCCAGCATCTGGGGGTAAATGATCCCTGCGCGATTAGCTGCGAACCGTTTATCCAGTGGGTGGTTGAAGATAACTTCAT
CGCTGGGCGTCCTGCCTGGGAAGTCGCAGGTGTACAAATGGTGAATGATGTCCTGCCATGGGAAGAGATGAAACTGCGTA
TGCTTAATGGCAGCCACTCTTTTCTCGCTTATCTGGGTTACCTCTCAGGATTCGCCTATATCAGTGATTGCATGCAGGAT
CGCGTATTTCGCTATGCTGCCAGAACATTAATGCTGGATGAGCAAGCGCCGACACTGCAAATTAAAGATGTCGATTTAAC
ACAATATGCGGATAAGTTAATTGCACGTTTTGCTAATCCGTCGCTGAAACATAAGACCTGGCAAATCGCGATGGATGGCA
GCCAGAAATTACCGCAACGTATGCTGGCAGGTATTCGCATACATCTGGGGCGCGAAACGGACTGGTCGTTGCTGGCATTA
GGCGTTGCTGGCTGGATGCGTTACGTCAGCGGCGTTGATGATGCCGGAAATGCCATTGATGTTCGCGATCCGCTTAGCGA
TAAAATTCGCGAACTTGTTGCGGGCAGCAGCAGTGAACAACGCGTAACCGCCCTGCTTTCCCTGCGTGAAGTTTTCGGTG
ATGATCTGCCAGATAACCCGCATTTTGTGCAGGCCATCGAACAAGCCTGGCAACAAATCGTACAATTCGGCGCACATCAG
GCGCTATTAAACACCCTCAAAATTTAA

Upstream 100 bases:

>100_bases
CCTCACACTTCATCGCATTAACAATCCAGACCAATTTCAATTGCTGTCATATAACTTTACACTGTCATTGTTAATTTATC
GTTACTAAGACGTGACTCCT

Downstream 100 bases:

>100_bases
CGATTTCTGCGGTTAAAGCGGATGAAGCTCACCTTCGTCCGCTCTCCCCTTCTCTTTTCTGCCTTTTTTAGCCAGGATTA
ACGCTCAGTTAACTTACCAG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
APGILVEALKRRRERSLTPFTVLSCDNIPDNGHVVKNAVLRMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFIAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAYISDCMQD
RVFRYAARTLMLDEQAPTLQIKDVDLTQYADKLIARFANPSLKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQ
ALLNTLKI

Sequences:

>Translated_488_residues
MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
APGILVEALKRRRERSLTPFTVLSCDNIPDNGHVVKNAVLRMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFIAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAYISDCMQD
RVFRYAARTLMLDEQAPTLQIKDVDLTQYADKLIARFANPSLKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQ
ALLNTLKI
>Mature_488_residues
MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
APGILVEALKRRRERSLTPFTVLSCDNIPDNGHVVKNAVLRMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFIAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAYISDCMQD
RVFRYAARTLMLDEQAPTLQIKDVDLTQYADKLIARFANPSLKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQ
ALLNTLKI

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxuB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=488, Percent_Identity=97.9508196721311, Blast_Score=993, Evalue=0.0,
Organism=Escherichia coli, GI1790779, Length=485, Percent_Identity=55.6701030927835, Blast_Score=552, Evalue=1e-158,
Organism=Escherichia coli, GI1787823, Length=464, Percent_Identity=54.3103448275862, Blast_Score=544, Evalue=1e-156,
Organism=Escherichia coli, GI1790028, Length=232, Percent_Identity=28.8793103448276, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI48994885, Length=485, Percent_Identity=22.8865979381443, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6324401, Length=492, Percent_Identity=39.2276422764228, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320765, Length=492, Percent_Identity=39.2276422764228, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 54243; Mature: 54243

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEI
CCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
SLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCE
AIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHSAPGILVEALKRRRERSLTPF
EEEEEEEECCCEEECCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
TVLSCDNIPDNGHVVKNAVLRMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
EEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHH
SQHLGVNDPCAISCEPFIQWVVEDNFIAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHS
HHHCCCCCCCEECHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHH
FLAYLGYLSGFAYISDCMQDRVFRYAARTLMLDEQAPTLQIKDVDLTQYADKLIARFANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHHCCC
SLKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLALGVAGWMRYVSGVDDAGNAID
CCCCCEEEEEECCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
VRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQ
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHH
ALLNTLKI
HHHHHHCC
>Mature Secondary Structure
MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEI
CCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
SLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCE
AIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHSAPGILVEALKRRRERSLTPF
EEEEEEEECCCEEECCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
TVLSCDNIPDNGHVVKNAVLRMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
EEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHH
SQHLGVNDPCAISCEPFIQWVVEDNFIAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHS
HHHCCCCCCCEECHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHH
FLAYLGYLSGFAYISDCMQDRVFRYAARTLMLDEQAPTLQIKDVDLTQYADKLIARFANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHHCCC
SLKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLALGVAGWMRYVSGVDDAGNAID
CCCCCEEEEEECCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
VRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQ
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHH
ALLNTLKI
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]