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The map label for this gene is wzx [H]

Identifier: 82543413

GI number: 82543413

Start: 877026

End: 878255

Strand: Reverse

Name: wzx [H]

Synonym: SBO_0862

Alternate gene names: 82543413

Gene position: 878255-877026 (Counterclockwise)

Preceding gene: 82543414

Following gene: 82543412

Centisome position: 19.43

GC content: 28.54

Gene sequence:

>1230_bases
GTGGTAAAAAAAATAGTTAATCAATTTATTTACCAGTTTGGGAATTATATTCTACCCTTTCTTATAATTCCTTTCTTAAT
CAATAAACTCTCTATTGCGGTCTATAAAGATTTTGTTGTTATTCAATCATTAGTATTATTTTTTGCTGTTTTAATTAATT
ATGGGCTGGATCTGTTTGGTGTTAGATATATTAGTAATAATGTAAAGCATCTAAGAAAATGTAAGAGTTTTCTTTATATT
TCCATATTGTCACGGCTCTGTATTTTTATATTTTGCTCATTCTTTTTGCTTGTGTCGTTGATGGCATTGACTAAACCCGA
CCTCCTTTATTGGTTGCTATGTTTTTTTTGGATGCTAAGCTTTGTATTTCAATCAAATTGGTATTTGCAAGGATGTGGTG
ATTTTAAGTTAATTACGTTCTATGGCTTACTTCCTAAGCTTATTGTTTATCCCTTCGTTTTTATTTTGGTCAATAATGAT
AATGATGCTTGGGTTTATCTATTTTTATGTGCAATAGCAAATTATGCATCAAACATACTAATGATGATACATATTAGGAG
GAAGTTGAATGTAGTAGCTTTTAAACGTACTAATTTGCTCAGAAATGTATGGATATTTTTAGTTAAAGGGTGGTATATAT
TCCTATCTCAAGCTAGTGTGACATTGATTTCTTATGCCAATATTTTCTTTCTACCTTTGGTGTTGGAACCTAAAAGTTTC
GTTGTCTTTTCAACTGCTGAAAGAATCGTGAAGGTGTTATCGATTACAACAACGCCTATTCTAAACGTTATTTTTCCACA
TATTTCATCATTAATTGAAAATAATAAACAAAGAGTATTTATAATGATTTCTCGAATATCATTATTTAGTTTAATTGTTT
TTCTGTTATGTTACACGTTGTATGTTTTTATAGGCTATTATCTCATACAGCTTATTTTTCCAACAATATCACAAGAATTA
TACTCTGTATTATTATTGTTGTTATTTAATGTATTCTTCGTATTCCAAAACAATCTCTTTGGTACACAAATTGGATTGAA
TTATGGGAAAGACAAAAGCTTCACTAAAATTATTGCAATCAATGGTATTTTAAATATTATAGCCATGCCTGTATTTAGTA
AACTGTATCACCTGCATGGCACAATATTAACATCCTTATGCATACAATTATCAATTTTGATATGTATGTATATGTTGGCT
AAAAAATGTGGTTATAAATTTAAGGTCTAA

Upstream 100 bases:

>100_bases
TCAAATAATTCGGAAAGCATTAAAGCCAGCATACAAAAAGAATGGTTATTTGAAATAAAAGTTAATAAAATTATCGAAGA
TATTATTCGAAGGAAAGAAT

Downstream 100 bases:

>100_bases
ATGAAAAAAATAGCTATTTTACTACCAGGACCAAGAAGGGAGCCTGTTGGTGGATATAAAGTCTTGTATCAATATGGAAA
CTATTTGGCATCTGTTGGAT

Product: O-antigen flippase

Products: lipopolysaccharide [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MVKKIVNQFIYQFGNYILPFLIIPFLINKLSIAVYKDFVVIQSLVLFFAVLINYGLDLFGVRYISNNVKHLRKCKSFLYI
SILSRLCIFIFCSFFLLVSLMALTKPDLLYWLLCFFWMLSFVFQSNWYLQGCGDFKLITFYGLLPKLIVYPFVFILVNND
NDAWVYLFLCAIANYASNILMMIHIRRKLNVVAFKRTNLLRNVWIFLVKGWYIFLSQASVTLISYANIFFLPLVLEPKSF
VVFSTAERIVKVLSITTTPILNVIFPHISSLIENNKQRVFIMISRISLFSLIVFLLCYTLYVFIGYYLIQLIFPTISQEL
YSVLLLLLFNVFFVFQNNLFGTQIGLNYGKDKSFTKIIAINGILNIIAMPVFSKLYHLHGTILTSLCIQLSILICMYMLA
KKCGYKFKV

Sequences:

>Translated_409_residues
MVKKIVNQFIYQFGNYILPFLIIPFLINKLSIAVYKDFVVIQSLVLFFAVLINYGLDLFGVRYISNNVKHLRKCKSFLYI
SILSRLCIFIFCSFFLLVSLMALTKPDLLYWLLCFFWMLSFVFQSNWYLQGCGDFKLITFYGLLPKLIVYPFVFILVNND
NDAWVYLFLCAIANYASNILMMIHIRRKLNVVAFKRTNLLRNVWIFLVKGWYIFLSQASVTLISYANIFFLPLVLEPKSF
VVFSTAERIVKVLSITTTPILNVIFPHISSLIENNKQRVFIMISRISLFSLIVFLLCYTLYVFIGYYLIQLIFPTISQEL
YSVLLLLLFNVFFVFQNNLFGTQIGLNYGKDKSFTKIIAINGILNIIAMPVFSKLYHLHGTILTSLCIQLSILICMYMLA
KKCGYKFKV
>Mature_409_residues
MVKKIVNQFIYQFGNYILPFLIIPFLINKLSIAVYKDFVVIQSLVLFFAVLINYGLDLFGVRYISNNVKHLRKCKSFLYI
SILSRLCIFIFCSFFLLVSLMALTKPDLLYWLLCFFWMLSFVFQSNWYLQGCGDFKLITFYGLLPKLIVYPFVFILVNND
NDAWVYLFLCAIANYASNILMMIHIRRKLNVVAFKRTNLLRNVWIFLVKGWYIFLSQASVTLISYANIFFLPLVLEPKSF
VVFSTAERIVKVLSITTTPILNVIFPHISSLIENNKQRVFIMISRISLFSLIVFLLCYTLYVFIGYYLIQLIFPTISQEL
YSVLLLLLFNVFFVFQNNLFGTQIGLNYGKDKSFTKIIAINGILNIIAMPVFSKLYHLHGTILTSLCIQLSILICMYMLA
KKCGYKFKV

Specific function: May be involved in the translocation process of the nascent O-polysaccharide molecules and/or its ligation to lipid A core units [H]

COG id: COG2244

COG function: function code R; Membrane protein involved in the export of O-antigen and teichoic acid

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788349, Length=399, Percent_Identity=24.0601503759398, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002797 [H]

Pfam domain/function: PF01943 Polysacc_synt [H]

EC number: NA

Molecular weight: Translated: 47679; Mature: 47679

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: lipopolysaccharide [Cytoplasm] [C]

Specific reaction: lipopolysaccharide [Cytoplasm] = lipopolysaccharide [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7517390; 7517391; 9097040; 9278503 [H]