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The map label for this gene is yliI

Identifier: 82543288

GI number: 82543288

Start: 750734

End: 751849

Strand: Direct

Name: yliI

Synonym: SBO_0733

Alternate gene names: 82543288

Gene position: 750734-751849 (Clockwise)

Preceding gene: 82543283

Following gene: 82543292

Centisome position: 16.61

GC content: 51.7

Gene sequence:

>1116_bases
ATGCATCGACAATCCTTTTTCCTTGTGCCCCTTATTTGTCTTTCTTCCGCTCTCTGGGCGGCTCCTGCAACGGTAAATGT
CGAAGTACTGCAAGACAAACTCGACCATCCCTGGGCACTGGCCTTTTTACCCGATAATCACGGTATGTTAATCACTCTGC
GCGGCGGCGAGTTGCGTCACTGGCAAGCAGGAAAAGGATTATCTGCGCCGCTTTCCGGAGTTCCGGACGTTTGGGCGCAC
GGGCAGGGCGGCCTGCTGGACGTGGTTTTAGCGCCTGATTTTGCTCAGTCTCGCCGCATCTGGTTAAGTTATTCCGAAGT
TGGCGATGATGGCAAAGCCGGAACTGCTGTGGGTTATGGCCGCTTAAGTGATGATCTCTCAAAAGTGACCGACTTCCGCA
CCGTCTTCCGCCAGATGCCAAAACTGTCTACCGGCAACCATTTTGGCGGGCGGCTGGTATTCGACGGTAAAGGTTATCTT
TTTATTGCTCTGGGCGAAAACAATCAGCGCCCGACGGCGCAGGATCTGGATAAATTACAGGGCAAACTGGTGCGTCTGAC
CGATCAGGGCGAAATCCCGGATGATAATCCTTTTATAAAGGAATCCGGTGCGCGCGCCGAGATCTGGTCTTATGGCATTC
GTAATCCGCAAGGAATGGCGATGAATCCGTGGAGTAATGCACTGTGGCTGAATGAACATGGCCCGCGCGGTGGTGATGAA
ATTAATATCCCGCAAAAAGGCAAAAACTACGGCTGGCCGCTGGCAACCTGGGGAATCAACTATTCAGGCTTTAAGATACC
GGAAGCGAAAGGGGAGATCGTCGCCGGGACCGAGCAACCTGTTTTTTACTGGAAAGATTCGCCCGCTGTGAGCGGCATGG
CCTTCTATAACAGCGATAAATTCCCCCAGTGGCAGCAAAAATTATTTATTGGCGCGCTGAAAGATAAAGATGTCATTGTG
ATGAGCGTCAACGGCGACAAAGTGACAGAAGATGGCCGTATTTTAACGGACAGAGGGCAGCGAATTCGTGATGTTCGCAC
TGGACCCGACGGTTATTTATACGTTCTCACCGACGAGTCCAGTGGGGAATTACTTAAAGTTAGCCCACGCAATTAG

Upstream 100 bases:

>100_bases
ATCATCTGTACTCCAATGACTAGTCTAAAAACTAGTATTAAGACTATCACTTATTTAAGTGATACTGGTTGTCTGGAGAT
TCAGGGGGCCAGTCTACGTT

Downstream 100 bases:

>100_bases
CTAACGGGAATCATCACCACTTTGCGCACTGCGGGGCGTTCAGTGAGTTGCTGATACCAGCGTTGCAGATTTGGACGCGG
TGTCCAGGTCAGGCCAACGT

Product: dehydrogenase

Products: NA

Alternate protein names: Asd

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAH
GQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIV
MSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN

Sequences:

>Translated_371_residues
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAH
GQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIV
MSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN
>Mature_371_residues
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAH
GQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIV
MSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family

Homologues:

Organism=Homo sapiens, GI187936953, Length=323, Percent_Identity=24.1486068111455, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI187936955, Length=198, Percent_Identity=28.2828282828283, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI124248546, Length=199, Percent_Identity=26.1306532663317, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1787060, Length=371, Percent_Identity=100, Blast_Score=759, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YLII_ECOLI (P75804)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   E64821
- RefSeq:   AP_001468.1
- RefSeq:   NP_415358.1
- PDB:   2G8S
- PDBsum:   2G8S
- ProteinModelPortal:   P75804
- SMR:   P75804
- STRING:   P75804
- EnsemblBacteria:   EBESCT00000001657
- EnsemblBacteria:   EBESCT00000016103
- GeneID:   945467
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0821
- KEGG:   eco:b0837
- EchoBASE:   EB3253
- EcoGene:   EG13480
- eggNOG:   COG2133
- GeneTree:   EBGT00050000010114
- HOGENOM:   HBG688942
- OMA:   VTEERIP
- ProtClustDB:   CLSK879785
- BioCyc:   EcoCyc:G6437-MONOMER
- BioCyc:   MetaCyc:G6437-MONOMER
- Genevestigator:   P75804
- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041
- Gene3D:   G3DSA:2.120.10.30

Pfam domain/function: PF07995 GSDH; SSF50952 Quino_gluc_DH

EC number: NA

Molecular weight: Translated: 41055; Mature: 41055

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: ACT_SITE 147-147 BINDING 82-82 BINDING 261-261

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRH
CCCCCEEHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEEEECCCCEEEEEECCCEEE
WQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYG
EECCCCCCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCEEEEEEHHCCCCCCCCCEEECC
RLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYLFIALGENNQRPTAQDLDKLQ
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHC
GKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
CEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEECCCCCEEEEECCCCCCCCE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDK
ECCCCCCCCCCCCEEECCCCCCCEECCCCCCCEEECCCCCEEEECCCCCCCEEEEECCCC
FPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDES
CCHHHHHHEEEEECCCCEEEEEECCCEECCCCEEEECCCCEEEHHCCCCCCEEEEEEECC
SGELLKVSPRN
CCCEEEECCCC
>Mature Secondary Structure
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRH
CCCCCEEHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEEEECCCCEEEEEECCCEEE
WQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYG
EECCCCCCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCEEEEEEHHCCCCCCCCCEEECC
RLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYLFIALGENNQRPTAQDLDKLQ
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHC
GKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
CEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEECCCCCEEEEECCCCCCCCE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDK
ECCCCCCCCCCCCEEECCCCCCCEECCCCCCCEEECCCCCEEEECCCCCCCEEEEECCCC
FPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDES
CCHHHHHHEEEEECCCCEEEEEECCCEECCCCEEEECCCCEEEHHCCCCCCEEEEEEECC
SGELLKVSPRN
CCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503