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The map label for this gene is aarA [H]

Identifier: 82543099

GI number: 82543099

Start: 537493

End: 539259

Strand: Direct

Name: aarA [H]

Synonym: SBO_0519

Alternate gene names: 82543099

Gene position: 537493-539259 (Clockwise)

Preceding gene: 82543091

Following gene: 82543100

Centisome position: 11.89

GC content: 49.8

Gene sequence:

>1767_bases
ATGTCTGCATCTTCGGTTAAGCCGTTAAATGTTCAATTACCCGCAATAACCCTTATCCTTTTTGCACTCTGTATTGGGAT
ATTTTGTTATCTCGCACAATGGATGAGTTATGAAGAGGTCGATCAATCCGCACTTATCCATCTCGGCGCAAACGTTGCGC
CTCTTACTTTGTCGGGTGAACCCTGGCGCTTATTGAGCAGTATCTTTCTGCACAGTAGTGTTTCTCATCTGCTGATGAAT
ATGTTTGCATTCCTGGTCGTGGGAGGCGTGGCGGAACAGATTCTGGGGAAATGGCGACTCCTGATTACCTGGTTATTCTC
CGGCGTCTTTGGTGGGCTCATCAGCGCCTGTTATGCGTTACGCGATAGTGATCAGATAGTCATCAGCGTTGGGGCATCCG
GGGCAATTATGGGAATAGCTGGCGCTGCGATAGCAACACAGCTTGCTTCAGGTGCGGGCACATACCATAAAAACCAGCGG
CGAGTATTTTCTCTGTTGGGTATGGTGGCGCTGACACTGTTGTATGGTGCCCGGCAAACAGGAATAGATAATGCTTGTCA
CATTGGCGGCCTGATTGCGGGTGGCGCGTTGGGTTGGCTGAGCGCGCGTTTATCTGGGCAAAACCGACTCGTTACGGAAG
GCGGGATTATTGTTGCGGGCAGTCTTCTTCTGACCGGGGCTATCTGGCTTGCGCAGCAGCAGATGGATGAGTCAGTTTTA
CAAGTCAGGCAAAGCCTGCGTGAAGCGTTTTATCCACAGGAGATTGAACAAGAGCGACGGCAAAAAAAGCAGCAGTTAGC
GGAGGAACGCAACGCCCTCAGGGAAACATTATCCGCTCCGGTAAGTCGTGAACAGGCCAGTGGTGATTTGCTCGCTGAGA
TTGCCGATATCCATGATATGGCGATCAGTCGGGATGGTAATATGTTGTATGCCGCAATTGAAAACACGAACAGCATTGTT
GTTTTCGACCTCGGACAAAAGAAAATCCTGCATACCTTTACAGCGCCCATAGCGAAAGAAAAGTCAGTCAAACATTGTGG
TGGCTGTAAAGATCAGGGCGTCAGATCGCTGGCATTAAGCCCGGATGAAAAGTTGATTTATGCGACTTCATTTGAAGCGA
ATGCGTTATCGGTCATTAACGTGGCGACAGGGGAGATTATTCAGTCGATTACCACCGGTGCACATCCTGACAGCCTTATC
CTCTCGCGTGATGGCACAAAAGCCTGGGTGATGAATCGCACCAGTAATAGTGTGTCAGCGATTGATCTGGTGACTTATCA
GCATGTGGCGGATATCCCGCTGGAGAAATACGACGGGGCGGGGACGAGCGGTAAACCAGGCGCCTGGGTTATGGCACTTT
CCCCGGATGAAAGAACATTACTGGTTCCGGGAGCAGGCAGAGGTAACATCGTGCGGATCAATACCATCACGCATCAGAAA
GAAGACTTTCCCGCAGGTGATGCGCGTGGAACGATATCGGCGATGCGTTTTCGACCTGAAAACGGCGAGGTTATTTTTGC
AGATAGTCAGGGGATTTCACGTATAAGCGTAGGGGATCAACAAGCCAGCATTATGACGCAATGGTGTAGCAGGAGCGTTT
ATTCCGTTGAGGGTATTAGCCCGGACGGTCAATATTTAGCGTTGGTGTCATATGGCCTGCAAGGTTATGTCATCCTGCTC
AATATTAATGCCGGGCAGATTATTGGCGTTTATCCTGCCAGCTACGTTAATCACCTTCGTTTTTCGGTAATGCTGCCAAC
TTACTGA

Upstream 100 bases:

>100_bases
TTCGGACAGAATTATCTTTTCGGCATGGGACGTTTGCCGGGATGATAACTGCACACGGGAAAAATGCTTTTTACCTGTCT
TTTCAAGGAAGAAACACCTT

Downstream 100 bases:

>100_bases
TTTAGTGTATGATGGTGATTTTAAGGTGCTTGCGTGGCTTCCATTTCCATCAGATGTCCTTCCTGCTCCGCTACTGAAGG
CGTGGTGCGTAACGGCAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MSASSVKPLNVQLPAITLILFALCIGIFCYLAQWMSYEEVDQSALIHLGANVAPLTLSGEPWRLLSSIFLHSSVSHLLMN
MFAFLVVGGVAEQILGKWRLLITWLFSGVFGGLISACYALRDSDQIVISVGASGAIMGIAGAAIATQLASGAGTYHKNQR
RVFSLLGMVALTLLYGARQTGIDNACHIGGLIAGGALGWLSARLSGQNRLVTEGGIIVAGSLLLTGAIWLAQQQMDESVL
QVRQSLREAFYPQEIEQERRQKKQQLAEERNALRETLSAPVSREQASGDLLAEIADIHDMAISRDGNMLYAAIENTNSIV
VFDLGQKKILHTFTAPIAKEKSVKHCGGCKDQGVRSLALSPDEKLIYATSFEANALSVINVATGEIIQSITTGAHPDSLI
LSRDGTKAWVMNRTSNSVSAIDLVTYQHVADIPLEKYDGAGTSGKPGAWVMALSPDERTLLVPGAGRGNIVRINTITHQK
EDFPAGDARGTISAMRFRPENGEVIFADSQGISRISVGDQQASIMTQWCSRSVYSVEGISPDGQYLALVSYGLQGYVILL
NINAGQIIGVYPASYVNHLRFSVMLPTY

Sequences:

>Translated_588_residues
MSASSVKPLNVQLPAITLILFALCIGIFCYLAQWMSYEEVDQSALIHLGANVAPLTLSGEPWRLLSSIFLHSSVSHLLMN
MFAFLVVGGVAEQILGKWRLLITWLFSGVFGGLISACYALRDSDQIVISVGASGAIMGIAGAAIATQLASGAGTYHKNQR
RVFSLLGMVALTLLYGARQTGIDNACHIGGLIAGGALGWLSARLSGQNRLVTEGGIIVAGSLLLTGAIWLAQQQMDESVL
QVRQSLREAFYPQEIEQERRQKKQQLAEERNALRETLSAPVSREQASGDLLAEIADIHDMAISRDGNMLYAAIENTNSIV
VFDLGQKKILHTFTAPIAKEKSVKHCGGCKDQGVRSLALSPDEKLIYATSFEANALSVINVATGEIIQSITTGAHPDSLI
LSRDGTKAWVMNRTSNSVSAIDLVTYQHVADIPLEKYDGAGTSGKPGAWVMALSPDERTLLVPGAGRGNIVRINTITHQK
EDFPAGDARGTISAMRFRPENGEVIFADSQGISRISVGDQQASIMTQWCSRSVYSVEGISPDGQYLALVSYGLQGYVILL
NINAGQIIGVYPASYVNHLRFSVMLPTY
>Mature_587_residues
SASSVKPLNVQLPAITLILFALCIGIFCYLAQWMSYEEVDQSALIHLGANVAPLTLSGEPWRLLSSIFLHSSVSHLLMNM
FAFLVVGGVAEQILGKWRLLITWLFSGVFGGLISACYALRDSDQIVISVGASGAIMGIAGAAIATQLASGAGTYHKNQRR
VFSLLGMVALTLLYGARQTGIDNACHIGGLIAGGALGWLSARLSGQNRLVTEGGIIVAGSLLLTGAIWLAQQQMDESVLQ
VRQSLREAFYPQEIEQERRQKKQQLAEERNALRETLSAPVSREQASGDLLAEIADIHDMAISRDGNMLYAAIENTNSIVV
FDLGQKKILHTFTAPIAKEKSVKHCGGCKDQGVRSLALSPDEKLIYATSFEANALSVINVATGEIIQSITTGAHPDSLIL
SRDGTKAWVMNRTSNSVSAIDLVTYQHVADIPLEKYDGAGTSGKPGAWVMALSPDERTLLVPGAGRGNIVRINTITHQKE
DFPAGDARGTISAMRFRPENGEVIFADSQGISRISVGDQQASIMTQWCSRSVYSVEGISPDGQYLALVSYGLQGYVILLN
INAGQIIGVYPASYVNHLRFSVMLPTY

Specific function: Rhomboid serine protease that catalyzes intramembrane proteolysis. Mediates quorum-sensing and the subsequent regulation of target genes via activation of the Tat protein export system. Catalyzes the proteolytic activation of tatA by removal of its N- ter

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 63271; Mature: 63139

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASSVKPLNVQLPAITLILFALCIGIFCYLAQWMSYEEVDQSALIHLGANVAPLTLSGE
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHEEECCCEEEEEECCC
PWRLLSSIFLHSSVSHLLMNMFAFLVVGGVAEQILGKWRLLITWLFSGVFGGLISACYAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDSDQIVISVGASGAIMGIAGAAIATQLASGAGTYHKNQRRVFSLLGMVALTLLYGARQT
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHC
GIDNACHIGGLIAGGALGWLSARLSGQNRLVTEGGIIVAGSLLLTGAIWLAQQQMDESVL
CCCCCHHHCCHHHCCHHHHHHHHCCCCCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHH
QVRQSLREAFYPQEIEQERRQKKQQLAEERNALRETLSAPVSREQASGDLLAEIADIHDM
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHH
AISRDGNMLYAAIENTNSIVVFDLGQKKILHTFTAPIAKEKSVKHCGGCKDQGVRSLALS
HCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHCCHHCCCCCHHCCCCCCCCCEEEECC
PDEKLIYATSFEANALSVINVATGEIIQSITTGAHPDSLILSRDGTKAWVMNRTSNSVSA
CCCCEEEEECCCCCCEEEEEEHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCEE
IDLVTYQHVADIPLEKYDGAGTSGKPGAWVMALSPDERTLLVPGAGRGNIVRINTITHQK
EEEHHHHHHHCCCHHHCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEEEECCC
EDFPAGDARGTISAMRFRPENGEVIFADSQGISRISVGDQQASIMTQWCSRSVYSVEGIS
CCCCCCCCCCCEEEEEEECCCCCEEEECCCCCEEEECCCHHHHHHHHHHCCCEEEECCCC
PDGQYLALVSYGLQGYVILLNINAGQIIGVYPASYVNHLRFSVMLPTY
CCCCEEEEEEECCCEEEEEEECCCCCEEEECCHHHHCCEEEEEECCCC
>Mature Secondary Structure 
SASSVKPLNVQLPAITLILFALCIGIFCYLAQWMSYEEVDQSALIHLGANVAPLTLSGE
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHEEECCCEEEEEECCC
PWRLLSSIFLHSSVSHLLMNMFAFLVVGGVAEQILGKWRLLITWLFSGVFGGLISACYAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDSDQIVISVGASGAIMGIAGAAIATQLASGAGTYHKNQRRVFSLLGMVALTLLYGARQT
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHC
GIDNACHIGGLIAGGALGWLSARLSGQNRLVTEGGIIVAGSLLLTGAIWLAQQQMDESVL
CCCCCHHHCCHHHCCHHHHHHHHCCCCCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHH
QVRQSLREAFYPQEIEQERRQKKQQLAEERNALRETLSAPVSREQASGDLLAEIADIHDM
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHH
AISRDGNMLYAAIENTNSIVVFDLGQKKILHTFTAPIAKEKSVKHCGGCKDQGVRSLALS
HCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHCCHHCCCCCHHCCCCCCCCCEEEECC
PDEKLIYATSFEANALSVINVATGEIIQSITTGAHPDSLILSRDGTKAWVMNRTSNSVSA
CCCCEEEEECCCCCCEEEEEEHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCEE
IDLVTYQHVADIPLEKYDGAGTSGKPGAWVMALSPDERTLLVPGAGRGNIVRINTITHQK
EEEHHHHHHHCCCHHHCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEEEECCC
EDFPAGDARGTISAMRFRPENGEVIFADSQGISRISVGDQQASIMTQWCSRSVYSVEGIS
CCCCCCCCCCCEEEEEEECCCCCEEEECCCCCEEEECCCHHHHHHHHHHCCCEEEECCCC
PDGQYLALVSYGLQGYVILLNINAGQIIGVYPASYVNHLRFSVMLPTY
CCCCEEEEEEECCCEEEEEEECCCCCEEEECCHHHHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8051030 [H]