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The map label for this gene is yqeF [H]

Identifier: 161984878

GI number: 161984878

Start: 2749461

End: 2750642

Strand: Reverse

Name: yqeF [H]

Synonym: SBO_2736

Alternate gene names: 161984878

Gene position: 2750642-2749461 (Counterclockwise)

Preceding gene: 82545146

Following gene: 82545144

Centisome position: 60.86

GC content: 53.47

Gene sequence:

>1182_bases
ATGAAAGACGTTGTGATTGTCGGGGCGTTACGGACACCTATCGGCTGCTTTCGTGGTGCGTTAGCGGGTCATTCCGCCGT
GGAACTTGGTAGTTTGGTCGTGAAAGCGTTAATAGAACGTACCGGCGTTCCTGCATATGCGGTGGATGAAGTAATTCTTG
GTCAGGTGTTGACTGCAGGGGCAGGGCAGAATCCGGCAAGGCAATCGGCTATTAAAGGTGGTCTTCCTAATAGCGTTTCT
GCAATCACTATTAATGACGTTTGCGGTTCTGGGCTTAAAGCACTGCATCTGGCTACTCAGGCGATACAGTGTGGCGAGGC
TGATATTGTCATCGCCGGTGGCCAGGAAAACATGAGCCGCGCACCACATGTTCTGACTGATAGCCGCACCGGTGCACAGC
TTGGCAATAGCCAGTTGGTTGACAGTCTGGTGCATGATGGGTTGTGGGATGCCTTCAATGATTATCATATTGGTGTCACC
GCCGAAAATCTGGCTCGCGAATATGGCATCAGCCGTCAGTTGCAGGATGCTTACGCACTTAGCTCGCAACAAAAAGCGCG
AGCGGCGATTGACGCCGGACGATTTAAAGATGAGATCGTCCCGGTAATGATCCAAAGTAACGGTCAGACGTTGGTTGTTG
ATACCGATGAACAGCCATGCACTGACGCCAGTGCAGAAGGTTTAGCCCGTTTAAATCCTTCATTTGATAGTCTCGGTTCT
GTGACCGCGGGGAATGCATCATCCATAAACGATGGCGCAGCTGCGGTAATGATGATGAGCGAAGCCAAAGCACGAGCGTT
GAATTTACCCGTGCTGGCCCGCATCCGCGCATTTGCCAGCGTTGGTGTAGATCCGGCATTGATGGGAATTGCGCCGGTGT
ATGCGACCCGCCGTTGCCTGGAGCGTGTAGGCTGGCAGTTGGCTGATGTCGATCTTATCGAGGCTAATGAAGCGTTTGCT
GCACAGGCGCTTTCGGTTGGCAAGATGCTTGAGTGGGATGAGCGTCGGGTCAATGTCAATGGTGGCGCGATCGCACTCGG
TCACCCGATAGGCGCTTCCGGTTGCCGAATCCTGGTTTCTCTGGTTCATGAAATGGTGAAACGTAATGCCCGCAAAGGGC
TGGCAACGCTTTGTATCGGCGGGGGCCAGGGCGTGGCATTGACCATTGAACGTGACGAGTAG

Upstream 100 bases:

>100_bases
GCATATTTCTTTTGTGATAAAAATCACTTTTTTTAAACAATTAAGATAACTGTAATTAACAATCATTTACTATTGCACTG
TTAATTGGTGCGAGGTTGTG

Downstream 100 bases:

>100_bases
CTCTGCATTTCCTCCTTACCGATAAATATCTGCCGTCATTAATCTGTTGAATAATGATGGCTGGCAAGTCGACATACATT
TTCTGGGCTCCCTCATTTTT

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVPAYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVS
AITINDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMIQSNGQTLVVDTDEQPCTDASAEGLARLNPSFDSLGS
VTAGNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFA
AQALSVGKMLEWDERRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERDE

Sequences:

>Translated_393_residues
MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVPAYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVS
AITINDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMIQSNGQTLVVDTDEQPCTDASAEGLARLNPSFDSLGS
VTAGNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFA
AQALSVGKMLEWDERRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERDE
>Mature_393_residues
MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVPAYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVS
AITINDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMIQSNGQTLVVDTDEQPCTDASAEGLARLNPSFDSLGS
VTAGNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFA
AQALSVGKMLEWDERRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERDE

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=391, Percent_Identity=48.5933503836317, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI4557237, Length=392, Percent_Identity=43.6224489795918, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI167614485, Length=397, Percent_Identity=42.3173803526448, Blast_Score=301, Evalue=7e-82,
Organism=Homo sapiens, GI4501853, Length=396, Percent_Identity=37.8787878787879, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI4504327, Length=430, Percent_Identity=31.3953488372093, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI194353979, Length=392, Percent_Identity=29.0816326530612, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI87082165, Length=393, Percent_Identity=99.236641221374, Blast_Score=784, Evalue=0.0,
Organism=Escherichia coli, GI1788554, Length=392, Percent_Identity=58.1632653061224, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1787663, Length=400, Percent_Identity=44, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI48994986, Length=401, Percent_Identity=40.8977556109726, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI1788683, Length=408, Percent_Identity=32.5980392156863, Blast_Score=194, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI133906874, Length=391, Percent_Identity=44.2455242966752, Blast_Score=317, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI25147385, Length=390, Percent_Identity=41.5384615384615, Blast_Score=289, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17535921, Length=392, Percent_Identity=40.3061224489796, Blast_Score=271, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17535917, Length=392, Percent_Identity=33.6734693877551, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17551802, Length=426, Percent_Identity=29.81220657277, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6325229, Length=398, Percent_Identity=41.4572864321608, Blast_Score=287, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6322031, Length=396, Percent_Identity=37.1212121212121, Blast_Score=225, Evalue=9e-60,
Organism=Drosophila melanogaster, GI24655093, Length=391, Percent_Identity=51.4066496163683, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24640423, Length=390, Percent_Identity=42.3076923076923, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI17648125, Length=391, Percent_Identity=41.6879795396419, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI17137578, Length=428, Percent_Identity=31.0747663551402, Blast_Score=173, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40964; Mature: 40964

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVPAYAVDEVILGQVLTAG
CCCEEEEECHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
AGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSR
CCCCHHHHHHHCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCC
APHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVTAENLAREYGISRQLQDAYAL
CCCEEECCCCCHHCCHHHHHHHHHHCCHHHCCCCEEEEEEHHHHHHHHCCHHHHHHHHHH
SSQQKARAAIDAGRFKDEIVPVMIQSNGQTLVVDTDEQPCTDASAEGLARLNPSFDSLGS
HHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCHHHCCCCHHHCCC
VTAGNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVDPALMGIAPVYATRRCL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ERVGWQLADVDLIEANEAFAAQALSVGKMLEWDERRVNVNGGAIALGHPIGASGCRILVS
HHHCCEEECEEEEECCHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCHHHHHHHH
LVHEMVKRNARKGLATLCIGGGQGVALTIERDE
HHHHHHHHHHHCCEEEEEEECCCEEEEEEECCC
>Mature Secondary Structure
MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVPAYAVDEVILGQVLTAG
CCCEEEEECHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
AGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSR
CCCCHHHHHHHCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCC
APHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVTAENLAREYGISRQLQDAYAL
CCCEEECCCCCHHCCHHHHHHHHHHCCHHHCCCCEEEEEEHHHHHHHHCCHHHHHHHHHH
SSQQKARAAIDAGRFKDEIVPVMIQSNGQTLVVDTDEQPCTDASAEGLARLNPSFDSLGS
HHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCHHHCCCCHHHCCC
VTAGNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVDPALMGIAPVYATRRCL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ERVGWQLADVDLIEANEAFAAQALSVGKMLEWDERRVNVNGGAIALGHPIGASGCRILVS
HHHCCEEECEEEEECCHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCHHHHHHHH
LVHEMVKRNARKGLATLCIGGGQGVALTIERDE
HHHHHHHHHHHCCEEEEEEECCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]