| Definition | Prochlorococcus marinus str. MIT 9312, complete genome. |
|---|---|
| Accession | NC_007577 |
| Length | 1,709,204 |
Click here to switch to the map view.
The map label for this gene is acnB [H]
Identifier: 78780178
GI number: 78780178
Start: 1686792
End: 1689365
Strand: Direct
Name: acnB [H]
Synonym: PMT9312_1793
Alternate gene names: 78780178
Gene position: 1686792-1689365 (Clockwise)
Preceding gene: 78780176
Following gene: 78780179
Centisome position: 98.69
GC content: 34.46
Gene sequence:
>2574_bases ATGAAGAATTTGGAAACATTGCTAAAAGATTATGCAGATCACGTAGCTGAAAGAGCTACCAAGGGTATACCTCCTTTACC TTTAAATGCTGAGCAAACAAATTGTATTACAAAATTATTGGAACAAGATAATACTTATGATTCATCTTATTTACTTGATT TACTAATAAATAGAGTACCACCAGGAGTTGATGAGGCTGCTTATGTAAAAGCAAGCTGGCTTACGGCTATTGTTAATTCC GAAAAATATTGCAAATCAATCAATCCCGAAAAAGCAATTGAAATACTAGGAACAATGATAGGCGGATACAATGTAAATTC TTTAGTTGAAATACTTAAAGGAGAAAATAGTTTACTTGCTAAAAAAGCGGCAGAAGTTTTAAAAAATATTATTCTTGTTT ACGACTCAGCTAATGAAATTTATGAATTATCTCAAAATAATATTTATGCAAAAGAGGTTGTAAATAGTTGGGCAAATGCA GAATGGTTCAAAAATAAAAAAGTTCTGGAGAAAGAGATTACTTGTTTAGTATTTAAAGTTGACGGTGAGACAAACACAGA CGACTTATCTCCGGCTGTACATGCAACAACACGCCCGGATATTCCGATGCATGCGTTAGCTATGTTGGAATTTAAAATAC CTGATGGACTAAAGATTCTTGATAATTTAAAAAAACAAAATTTACCGATAGCTTATGTTGGAGATGTTGTTGGAACAGGG AGTTCTAGAAAATCTGCTATTAATTCACTCATTTGGCATATAGGAGAAGATATCGCTTATGTTCCAAACAAAAAAACAGG TGGAATAATAATTGGCAACAAAATAGCCCCAATTTTCTTTAATACTGCACAAGATTCAGGTGCTTTACCTATAGAAGCTG ACGTATCTCATATGAAAACAGGAGATGTTATTAAAATATATCCTTATAAAGGCATTATTAAAAAAATTGAACAAGACTCG AATACTGAAGAATTAATAAGCAAATTCGACTTGTATCCATCAACTCTTACTGATGAAATTCAAGCTGGCGGAAGAATTAA TCTTATGATTGGAAGATCTCTTACGGACAAAATTAGAACCAAATTAAATTATCAACCAAGTGAAATATTTACCAGACCAC AAAATCCAACCGAAAGTACTGCCGGCTTTACTCAAGCTCAAAAAATAGTAGGCAAAGCATGCGGTTTAGATGGAGTTAGG CCAGGAATGACCTGTGAGCCAATTATGACCACGGTTGGTAGTCAAGATACTACTGGGCCAATGACTAGAGATGAACTAAA AGAACTAGCTTGTTTAGGATTTACTGCAGATTTAGTGATGCAAAGTTTTTGTCATACAGCTGCATATCCTAAACCAGTAG ATCTAGTTACCCATAAAGAATTACCTGATTTTATATCTCAAAGAGGTGGAGTAGCTCTTAAGCCTGGAGACGGCATAATT CATAGTTGGCTTAACAGAATGCTGCTCCCCGATACTGTTGGCACAGGTGGAGATAGTCATACAAGATTTCCTCTTGGCAT TTCATTTCCTGGAGGCTCGGGCATTGTTGCCTTTGCCGCTGCAATAGGATCAATGCCATTAAATATGCCGGAATCTGTAC TGGTTAAATTTAAGGGGGAATTATTACCAGGAATTACTCTGAGAGATTTAGTAAATGCAATCCCTCTATTCGCAATTAAA AAAGGACTCTTAACTGTTGAGAAAGAAAATAAGAAAAATATATTTAACGGTAAAATTATGGAAATTGAGGGATTACCAAA CCTAAAACTTGAACAAGCTTTTGAACTTACTGATGCTACTGCAGAACGCTCATGCGCTGGTAGCACCATACTTTTATCCC AAGAAACTGTTCAAGAGTACTTAAGAAGCAATATTTGCCTACTAGAAAAAATGATTGAGAGCAATTATGAAGATTCAAAA TCGATTTCAAGAAGAATCAATGATATGAAAAATTGGTTAAAAAAACCTAAATTAATTCAGCCAGATAAGAACGCCAAGTA TGAAGAAATCATTGAAATTGAATTAGCAAAAGTTACACAACCTATAGTTGCTTGCCCTAACGATCCAGATAATGTAAAAG AAATCACTGATGTTGCAAATACAAATATTGACGAGGTTTTTATAGGTTCTTGCATGACAAATATTGGTCATTACAGGGCA GCTGCGAAAGTTCTTGAAGGTGTACAAAATTTAAAATCTAAATTATGGATTTGTCCACCAACAAAAATGGATGAAGAAAC TCTAAAAGCTGAAGGCTACTATAAAATATTCGAAGATTGTGGTGCAAGGTTAGAGTTACCAGGCTGTTCTTTATGTATGG GAAATCAAGCCAGAGTAGATGAAGGTTCTGTAGTATTTTCTACAAGTACAAGAAATTTTGACAATAGACTTGGCAAGAAT GCACAAGTCTTTTTAGGCAGCGCTGAATTAGCAGCAGTTTGCGCACTACTTGGAAAAATACCTGAAGTTGAAGAATATCA GGATATTACTAAAAATAAAATTAATCCATATTCAGATGAACTTTATCGCTATCTTCAATTTGATGAAATACACGATTTCA GCTTGACAAAGTAA
Upstream 100 bases:
>100_bases CATTGATTAATTAAGAAGTTTGAATATTTAAAAAAGCATTTATGAATACTCTCCTTTTCAATATTAAAAATAACAATAGA TTAGGCATTAAACCTTACTA
Downstream 100 bases:
>100_bases TCATGGACTATGCCAAACTTTATAAAAGATAATATTCAAAAAACAAGTAATAATTCTTCTCGTAGCATTAAAAAATTATT AAGACAAAGATCTCTAGTCG
Product: bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
Products: NA
Alternate protein names: Aconitase 2; 2-methylisocitrate dehydratase; Citrate hydro-lyase 2 [H]
Number of amino acids: Translated: 857; Mature: 857
Protein sequence:
>857_residues MKNLETLLKDYADHVAERATKGIPPLPLNAEQTNCITKLLEQDNTYDSSYLLDLLINRVPPGVDEAAYVKASWLTAIVNS EKYCKSINPEKAIEILGTMIGGYNVNSLVEILKGENSLLAKKAAEVLKNIILVYDSANEIYELSQNNIYAKEVVNSWANA EWFKNKKVLEKEITCLVFKVDGETNTDDLSPAVHATTRPDIPMHALAMLEFKIPDGLKILDNLKKQNLPIAYVGDVVGTG SSRKSAINSLIWHIGEDIAYVPNKKTGGIIIGNKIAPIFFNTAQDSGALPIEADVSHMKTGDVIKIYPYKGIIKKIEQDS NTEELISKFDLYPSTLTDEIQAGGRINLMIGRSLTDKIRTKLNYQPSEIFTRPQNPTESTAGFTQAQKIVGKACGLDGVR PGMTCEPIMTTVGSQDTTGPMTRDELKELACLGFTADLVMQSFCHTAAYPKPVDLVTHKELPDFISQRGGVALKPGDGII HSWLNRMLLPDTVGTGGDSHTRFPLGISFPGGSGIVAFAAAIGSMPLNMPESVLVKFKGELLPGITLRDLVNAIPLFAIK KGLLTVEKENKKNIFNGKIMEIEGLPNLKLEQAFELTDATAERSCAGSTILLSQETVQEYLRSNICLLEKMIESNYEDSK SISRRINDMKNWLKKPKLIQPDKNAKYEEIIEIELAKVTQPIVACPNDPDNVKEITDVANTNIDEVFIGSCMTNIGHYRA AAKVLEGVQNLKSKLWICPPTKMDEETLKAEGYYKIFEDCGARLELPGCSLCMGNQARVDEGSVVFSTSTRNFDNRLGKN AQVFLGSAELAAVCALLGKIPEVEEYQDITKNKINPYSDELYRYLQFDEIHDFSLTK
Sequences:
>Translated_857_residues MKNLETLLKDYADHVAERATKGIPPLPLNAEQTNCITKLLEQDNTYDSSYLLDLLINRVPPGVDEAAYVKASWLTAIVNS EKYCKSINPEKAIEILGTMIGGYNVNSLVEILKGENSLLAKKAAEVLKNIILVYDSANEIYELSQNNIYAKEVVNSWANA EWFKNKKVLEKEITCLVFKVDGETNTDDLSPAVHATTRPDIPMHALAMLEFKIPDGLKILDNLKKQNLPIAYVGDVVGTG SSRKSAINSLIWHIGEDIAYVPNKKTGGIIIGNKIAPIFFNTAQDSGALPIEADVSHMKTGDVIKIYPYKGIIKKIEQDS NTEELISKFDLYPSTLTDEIQAGGRINLMIGRSLTDKIRTKLNYQPSEIFTRPQNPTESTAGFTQAQKIVGKACGLDGVR PGMTCEPIMTTVGSQDTTGPMTRDELKELACLGFTADLVMQSFCHTAAYPKPVDLVTHKELPDFISQRGGVALKPGDGII HSWLNRMLLPDTVGTGGDSHTRFPLGISFPGGSGIVAFAAAIGSMPLNMPESVLVKFKGELLPGITLRDLVNAIPLFAIK KGLLTVEKENKKNIFNGKIMEIEGLPNLKLEQAFELTDATAERSCAGSTILLSQETVQEYLRSNICLLEKMIESNYEDSK SISRRINDMKNWLKKPKLIQPDKNAKYEEIIEIELAKVTQPIVACPNDPDNVKEITDVANTNIDEVFIGSCMTNIGHYRA AAKVLEGVQNLKSKLWICPPTKMDEETLKAEGYYKIFEDCGARLELPGCSLCMGNQARVDEGSVVFSTSTRNFDNRLGKN AQVFLGSAELAAVCALLGKIPEVEEYQDITKNKINPYSDELYRYLQFDEIHDFSLTK >Mature_857_residues MKNLETLLKDYADHVAERATKGIPPLPLNAEQTNCITKLLEQDNTYDSSYLLDLLINRVPPGVDEAAYVKASWLTAIVNS EKYCKSINPEKAIEILGTMIGGYNVNSLVEILKGENSLLAKKAAEVLKNIILVYDSANEIYELSQNNIYAKEVVNSWANA EWFKNKKVLEKEITCLVFKVDGETNTDDLSPAVHATTRPDIPMHALAMLEFKIPDGLKILDNLKKQNLPIAYVGDVVGTG SSRKSAINSLIWHIGEDIAYVPNKKTGGIIIGNKIAPIFFNTAQDSGALPIEADVSHMKTGDVIKIYPYKGIIKKIEQDS NTEELISKFDLYPSTLTDEIQAGGRINLMIGRSLTDKIRTKLNYQPSEIFTRPQNPTESTAGFTQAQKIVGKACGLDGVR PGMTCEPIMTTVGSQDTTGPMTRDELKELACLGFTADLVMQSFCHTAAYPKPVDLVTHKELPDFISQRGGVALKPGDGII HSWLNRMLLPDTVGTGGDSHTRFPLGISFPGGSGIVAFAAAIGSMPLNMPESVLVKFKGELLPGITLRDLVNAIPLFAIK KGLLTVEKENKKNIFNGKIMEIEGLPNLKLEQAFELTDATAERSCAGSTILLSQETVQEYLRSNICLLEKMIESNYEDSK SISRRINDMKNWLKKPKLIQPDKNAKYEEIIEIELAKVTQPIVACPNDPDNVKEITDVANTNIDEVFIGSCMTNIGHYRA AAKVLEGVQNLKSKLWICPPTKMDEETLKAEGYYKIFEDCGARLELPGCSLCMGNQARVDEGSVVFSTSTRNFDNRLGKN AQVFLGSAELAAVCALLGKIPEVEEYQDITKNKINPYSDELYRYLQFDEIHDFSLTK
Specific function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well as the dehydration of 2-methylisocitrate to cis-2-methylaconitate [H]
COG id: COG1049
COG function: function code C; Aconitase B
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aconitase/IPM isomerase family [H]
Homologues:
Organism=Homo sapiens, GI4501867, Length=414, Percent_Identity=24.6376811594203, Blast_Score=68, Evalue=3e-11, Organism=Escherichia coli, GI2367097, Length=860, Percent_Identity=58.953488372093, Blast_Score=1014, Evalue=0.0, Organism=Escherichia coli, GI1786259, Length=396, Percent_Identity=25, Blast_Score=80, Evalue=6e-16, Organism=Saccharomyces cerevisiae, GI6322261, Length=408, Percent_Identity=25.4901960784314, Blast_Score=85, Evalue=4e-17, Organism=Saccharomyces cerevisiae, GI6321429, Length=407, Percent_Identity=24.5700245700246, Blast_Score=76, Evalue=3e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015931 - InterPro: IPR015937 - InterPro: IPR001030 - InterPro: IPR015928 - InterPro: IPR018136 - InterPro: IPR004406 - InterPro: IPR015930 - InterPro: IPR015933 - InterPro: IPR015929 [H]
Pfam domain/function: PF00330 Aconitase; PF06434 Aconitase_2_N; PF11791 Aconitase_B_N [H]
EC number: =4.2.1.3; =4.2.1.99 [H]
Molecular weight: Translated: 94594; Mature: 94594
Theoretical pI: Translated: 5.17; Mature: 5.17
Prosite motif: PS00450 ACONITASE_1 ; PS01244 ACONITASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNLETLLKDYADHVAERATKGIPPLPLNAEQTNCITKLLEQDNTYDSSYLLDLLINRVP CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCC PGVDEAAYVKASWLTAIVNSEKYCKSINPEKAIEILGTMIGGYNVNSLVEILKGENSLLA CCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHH KKAAEVLKNIILVYDSANEIYELSQNNIYAKEVVNSWANAEWFKNKKVLEKEITCLVFKV HHHHHHHHHHEEEECCCHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEE DGETNTDDLSPAVHATTRPDIPMHALAMLEFKIPDGLKILDNLKKQNLPIAYVGDVVGTG CCCCCCCCCCCCEECCCCCCCCHHHHHEEEEECCCCHHHHHHHHHCCCCEEEECCHHCCC SSRKSAINSLIWHIGEDIAYVPNKKTGGIIIGNKIAPIFFNTAQDSGALPIEADVSHMKT CHHHHHHHHHHHHHCCCCEECCCCCCCCEEECCCCCEEEEECCCCCCCCCEECCHHHCCC GDVIKIYPYKGIIKKIEQDSNTEELISKFDLYPSTLTDEIQAGGRINLMIGRSLTDKIRT CCEEEECCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCCEEEEEECCCHHHHHHH KLNYQPSEIFTRPQNPTESTAGFTQAQKIVGKACGLDGVRPGMTCEPIMTTVGSQDTTGP HCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCC MTRDELKELACLGFTADLVMQSFCHTAAYPKPVDLVTHKELPDFISQRGGVALKPGDGII CCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCHH HSWLNRMLLPDTVGTGGDSHTRFPLGISFPGGSGIVAFAAAIGSMPLNMPESVLVKFKGE HHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCC LLPGITLRDLVNAIPLFAIKKGLLTVEKENKKNIFNGKIMEIEGLPNLKLEQAFELTDAT CCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHH AERSCAGSTILLSQETVQEYLRSNICLLEKMIESNYEDSKSISRRINDMKNWLKKPKLIQ HHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC PDKNAKYEEIIEIELAKVTQPIVACPNDPDNVKEITDVANTNIDEVFIGSCMTNIGHYRA CCCCCCHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH AAKVLEGVQNLKSKLWICPPTKMDEETLKAEGYYKIFEDCGARLELPGCSLCMGNQARVD HHHHHHHHHHHHHCEEECCCCCCCHHHHHCCCHHHHHHHCCCEEECCCCCEECCCCCCCC EGSVVFSTSTRNFDNRLGKNAQVFLGSAELAAVCALLGKIPEVEEYQDITKNKINPYSDE CCCEEEEECCCCHHHHHCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHH LYRYLQFDEIHDFSLTK HHHHHHHHCCCCCCCCC >Mature Secondary Structure MKNLETLLKDYADHVAERATKGIPPLPLNAEQTNCITKLLEQDNTYDSSYLLDLLINRVP CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCC PGVDEAAYVKASWLTAIVNSEKYCKSINPEKAIEILGTMIGGYNVNSLVEILKGENSLLA CCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHH KKAAEVLKNIILVYDSANEIYELSQNNIYAKEVVNSWANAEWFKNKKVLEKEITCLVFKV HHHHHHHHHHEEEECCCHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEE DGETNTDDLSPAVHATTRPDIPMHALAMLEFKIPDGLKILDNLKKQNLPIAYVGDVVGTG CCCCCCCCCCCCEECCCCCCCCHHHHHEEEEECCCCHHHHHHHHHCCCCEEEECCHHCCC SSRKSAINSLIWHIGEDIAYVPNKKTGGIIIGNKIAPIFFNTAQDSGALPIEADVSHMKT CHHHHHHHHHHHHHCCCCEECCCCCCCCEEECCCCCEEEEECCCCCCCCCEECCHHHCCC GDVIKIYPYKGIIKKIEQDSNTEELISKFDLYPSTLTDEIQAGGRINLMIGRSLTDKIRT CCEEEECCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCCEEEEEECCCHHHHHHH KLNYQPSEIFTRPQNPTESTAGFTQAQKIVGKACGLDGVRPGMTCEPIMTTVGSQDTTGP HCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCC MTRDELKELACLGFTADLVMQSFCHTAAYPKPVDLVTHKELPDFISQRGGVALKPGDGII CCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCHH HSWLNRMLLPDTVGTGGDSHTRFPLGISFPGGSGIVAFAAAIGSMPLNMPESVLVKFKGE HHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCC LLPGITLRDLVNAIPLFAIKKGLLTVEKENKKNIFNGKIMEIEGLPNLKLEQAFELTDAT CCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHH AERSCAGSTILLSQETVQEYLRSNICLLEKMIESNYEDSKSISRRINDMKNWLKKPKLIQ HHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC PDKNAKYEEIIEIELAKVTQPIVACPNDPDNVKEITDVANTNIDEVFIGSCMTNIGHYRA CCCCCCHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH AAKVLEGVQNLKSKLWICPPTKMDEETLKAEGYYKIFEDCGARLELPGCSLCMGNQARVD HHHHHHHHHHHHHCEEECCCCCCCHHHHHCCCHHHHHHHCCCEEECCCCCEECCCCCCCC EGSVVFSTSTRNFDNRLGKNAQVFLGSAELAAVCALLGKIPEVEEYQDITKNKINPYSDE CCCEEEEECCCCHHHHHCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHH LYRYLQFDEIHDFSLTK HHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]