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The map label for this gene is trpE2 [H]

Identifier: 78780170

GI number: 78780170

Start: 1677442

End: 1678755

Strand: Direct

Name: trpE2 [H]

Synonym: PMT9312_1785

Alternate gene names: 78780170

Gene position: 1677442-1678755 (Clockwise)

Preceding gene: 78780169

Following gene: 78780171

Centisome position: 98.14

GC content: 29.15

Gene sequence:

>1314_bases
ATGAAAATAAAAACAATACTTTTAAAAAGATGGGTAGATCCAGAACTAATTACGTACCATCTAACAAAAAAATTTGGAGA
TAAAGGATTAGCTTGGTTAGACAGTGATGGCAAAGAAAATGGTGAATGGTCAATAATAGGGATTAAACCAAAAAAAATAA
TCCAATCAAGAGATATAAATAACTTAGACAAAAATAATAATCCCTTTAACAATTTAAAAGATATTAATAAAGGATTTTGG
ATTGGATGGTTAAGTTATGAGGCTGGTGCATACATTGAACCCAAAAACCCTTGGCGACAATCTGCAATGGCAACTTTATG
GATTGCATCATATGATCCAATCATTAAATGCAACCTAATAAAAAAAGAAATAATTATCGAAGGCACCAAATCAGATGAAC
TGATAAATTATCAAAATATAATTAATAATATAAATATTTTAGAAGAAAAGAATGTTATAAAAACAAATTTGAATTTCGAT
TTTTCAAAAATCAATTTGGAAAAAATGACTGAAAAATTTCAGGAAAATATTTTACACTTAAAAAAGTTAATCTCATTAGG
AGATTTATTTCAAGCAAACCTAACTACTAAATGCGAAATTAAATCTTCCAAAAACCATAGTCCTCTTGATATTTATTTAA
AAATAAGAAGGAAATTAAGAGCTCCCTTCGGAGGAATAATAGTAAATGATAATTATAAAGAGGCGGTATTATCTACCTCG
CCAGAAAGATTTATAAAAATAGATAATAAAAATTTTGTAGAATCAAGACCTATCAAAGGAACTAGATCCAGGGATAAGGA
TTTAAATCAAGACGCACTTAATGCTATCGATTTAATAACGAACGAAAAAGATAGAGCCGAAAATATTATGATTGTTGACC
TAATAAGAAATGATTTAAGTAAAGTTTGCGAAACAGGAAGCATTATGGTGCCAGAAATATTAAAACTTGAAAGTTTCTTA
AAAGTTCATCATCTAACTTCAGTAATCAGAGGAAAATTAAAAAAAGACAAGAACTGGATTGATTTACTAAAAGCTTGTTG
GCCTGGGGGCTCTATAACTGGAGCACCTAAATTAAGATCATGCCAAAGACTTTTTGAATTAGAAGAATATGACCGCGGAC
CATATTGTGGCTCATTTTTGAAGCTTGACTGGAATGGGGAGTTTGACAGCAATATACTAATAAGATCATTTTTAATTAAA
GACAAAAAAATCAATATATATGCTGGTTGCGGAATAGTTATTGACTCTAATCCTGAAGAGGAAACTAATGAACTAAAGTG
GAAACTTTTACCATTAATTGATTCACTAAAATGA

Upstream 100 bases:

>100_bases
GGAGTTGTTATTCAGGTGATGCAAAACCATGCGGAAAGTGTGATAGTTGCAGAATTAGGAATACCGCTTATAAAAAATGG
CTCAATAATAAAAATAAAAA

Downstream 100 bases:

>100_bases
TAGAAACATTAGGCTGGCACAAGGATCAATGGTTAGATATTGATAGAATATTTTTTGCTGCTAATAATAGAGGATTAAAA
TTTGCTGATGGTATATTTGA

Product: putative p-aminobenzoate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKIKTILLKRWVDPELITYHLTKKFGDKGLAWLDSDGKENGEWSIIGIKPKKIIQSRDINNLDKNNNPFNNLKDINKGFW
IGWLSYEAGAYIEPKNPWRQSAMATLWIASYDPIIKCNLIKKEIIIEGTKSDELINYQNIINNINILEEKNVIKTNLNFD
FSKINLEKMTEKFQENILHLKKLISLGDLFQANLTTKCEIKSSKNHSPLDIYLKIRRKLRAPFGGIIVNDNYKEAVLSTS
PERFIKIDNKNFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLSKVCETGSIMVPEILKLESFL
KVHHLTSVIRGKLKKDKNWIDLLKACWPGGSITGAPKLRSCQRLFELEEYDRGPYCGSFLKLDWNGEFDSNILIRSFLIK
DKKINIYAGCGIVIDSNPEEETNELKWKLLPLIDSLK

Sequences:

>Translated_437_residues
MKIKTILLKRWVDPELITYHLTKKFGDKGLAWLDSDGKENGEWSIIGIKPKKIIQSRDINNLDKNNNPFNNLKDINKGFW
IGWLSYEAGAYIEPKNPWRQSAMATLWIASYDPIIKCNLIKKEIIIEGTKSDELINYQNIINNINILEEKNVIKTNLNFD
FSKINLEKMTEKFQENILHLKKLISLGDLFQANLTTKCEIKSSKNHSPLDIYLKIRRKLRAPFGGIIVNDNYKEAVLSTS
PERFIKIDNKNFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLSKVCETGSIMVPEILKLESFL
KVHHLTSVIRGKLKKDKNWIDLLKACWPGGSITGAPKLRSCQRLFELEEYDRGPYCGSFLKLDWNGEFDSNILIRSFLIK
DKKINIYAGCGIVIDSNPEEETNELKWKLLPLIDSLK
>Mature_437_residues
MKIKTILLKRWVDPELITYHLTKKFGDKGLAWLDSDGKENGEWSIIGIKPKKIIQSRDINNLDKNNNPFNNLKDINKGFW
IGWLSYEAGAYIEPKNPWRQSAMATLWIASYDPIIKCNLIKKEIIIEGTKSDELINYQNIINNINILEEKNVIKTNLNFD
FSKINLEKMTEKFQENILHLKKLISLGDLFQANLTTKCEIKSSKNHSPLDIYLKIRRKLRAPFGGIIVNDNYKEAVLSTS
PERFIKIDNKNFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLSKVCETGSIMVPEILKLESFL
KVHHLTSVIRGKLKKDKNWIDLLKACWPGGSITGAPKLRSCQRLFELEEYDRGPYCGSFLKLDWNGEFDSNILIRSFLIK
DKKINIYAGCGIVIDSNPEEETNELKWKLLPLIDSLK

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=377, Percent_Identity=32.3607427055703, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1787518, Length=265, Percent_Identity=30.9433962264151, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786809, Length=196, Percent_Identity=28.0612244897959, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082077, Length=193, Percent_Identity=30.0518134715026, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=441, Percent_Identity=29.2517006802721, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6324361, Length=269, Percent_Identity=30.8550185873606, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR010118 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 50381; Mature: 50381

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKTILLKRWVDPELITYHLTKKFGDKGLAWLDSDGKENGEWSIIGIKPKKIIQSRDIN
CCHHHHHHHHCCCHHHEEEHHHHHHCCCCCEEECCCCCCCCCEEEEECCHHHHHHHCCCC
NLDKNNNPFNNLKDINKGFWIGWLSYEAGAYIEPKNPWRQSAMATLWIASYDPIIKCNLI
CCCCCCCCCHHHHHCCCCEEEEEEEECCCCEECCCCHHHHHHEEEEEEECCCCEEEEEEE
KKEIIIEGTKSDELINYQNIINNINILEEKNVIKTNLNFDFSKINLEKMTEKFQENILHL
EEEEEEECCCCCCCCCHHHHHCCCCEEECCCEEEECCCCCHHCCCHHHHHHHHHHHHHHH
KKLISLGDLFQANLTTKCEIKSSKNHSPLDIYLKIRRKLRAPFGGIIVNDNYKEAVLSTS
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCC
PERFIKIDNKNFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLS
CCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCEEEHHHHHHHHH
KVCETGSIMVPEILKLESFLKVHHLTSVIRGKLKKDKNWIDLLKACWPGGSITGAPKLRS
HHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHH
CQRLFELEEYDRGPYCGSFLKLDWNGEFDSNILIRSFLIKDKKINIYAGCGIVIDSNPEE
HHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEEEEEEEECCCCCC
ETNELKWKLLPLIDSLK
CHHHHHEEEECHHHCCC
>Mature Secondary Structure
MKIKTILLKRWVDPELITYHLTKKFGDKGLAWLDSDGKENGEWSIIGIKPKKIIQSRDIN
CCHHHHHHHHCCCHHHEEEHHHHHHCCCCCEEECCCCCCCCCEEEEECCHHHHHHHCCCC
NLDKNNNPFNNLKDINKGFWIGWLSYEAGAYIEPKNPWRQSAMATLWIASYDPIIKCNLI
CCCCCCCCCHHHHHCCCCEEEEEEEECCCCEECCCCHHHHHHEEEEEEECCCCEEEEEEE
KKEIIIEGTKSDELINYQNIINNINILEEKNVIKTNLNFDFSKINLEKMTEKFQENILHL
EEEEEEECCCCCCCCCHHHHHCCCCEEECCCEEEECCCCCHHCCCHHHHHHHHHHHHHHH
KKLISLGDLFQANLTTKCEIKSSKNHSPLDIYLKIRRKLRAPFGGIIVNDNYKEAVLSTS
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCC
PERFIKIDNKNFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLS
CCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCEEEHHHHHHHHH
KVCETGSIMVPEILKLESFLKVHHLTSVIRGKLKKDKNWIDLLKACWPGGSITGAPKLRS
HHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHH
CQRLFELEEYDRGPYCGSFLKLDWNGEFDSNILIRSFLIKDKKINIYAGCGIVIDSNPEE
HHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEEEEEEEECCCCCC
ETNELKWKLLPLIDSLK
CHHHHHEEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]