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The map label for this gene is fabF [H]

Identifier: 78780087

GI number: 78780087

Start: 1590257

End: 1591501

Strand: Direct

Name: fabF [H]

Synonym: PMT9312_1702

Alternate gene names: 78780087

Gene position: 1590257-1591501 (Clockwise)

Preceding gene: 78780086

Following gene: 78780088

Centisome position: 93.04

GC content: 40.0

Gene sequence:

>1245_bases
ATGCCAAATTTCCATCGAGTAGTTATTACCGGTATCGGAGCAGTAACTCCAATTGGTAACAACATTGATGAATATTTACT
AAGTCTTCAAAAAGGTGCTAATGGTGTCTCAGGTATCACTCTGTTTGATCCAGTAGATCATCCTTGCAAATTTGCAGCAG
AAGTTAAAAATCTTCAATCTCAAAATTTCATAGAAGCCAAAGAATCCAAAAGGTGGGATCGTTTCTCACAGTTTGGAGTT
ATTGCTGCAAAGCAAGCCTTTAATGATTCTGGTCTTGAAATTAATGAAGCTAATGCATCAAGAATTGGAGTGATTATTGG
CTCAGGTGTTGGAGGCTTACTAACTATGGAAAGTCAAGCTCAAATACTGAGTCATAAAGGGCCAAAAAGAGTAAGTCCAT
TTACAGTCCCAATGATGATTCCAAATATGGCAACTGGACTAGCTGCCATTGCTTTGGGTGCAAAAGGCCCAAGTTCCTCT
GTTTCCACTGCTTGCGCTGCTGGCTCTAATGCAATTGGTGATTCTTTTAGATTACTCCAACTTGGAAAAGCAGATGCAAT
GATCTGTGGAGGTGCAGAAGCAAGTATTACACCTCTTGGAGTAGCTGGCTTTGCCAGTGCCAAAGCTCTTTCATTCAGGA
ATGAAAGTCCCCAGACAGCTAGTAGACCTTTTGATGCTGAAAGAGACGGTTTTGTTATTGGAGAGGGTTCCGGCATTCTT
GTGTTAGAAACTTTAGAGAATGCTCAAAAAAGGGATGCAAGAATCTATGGAGAAATTATTGGATATGGAACAACATGCGA
TGCTCATCACATCACTGCTCCCTCTCCAGGTGGAGTTGGAGGTGCAGAGGCTATCAAACTAGCAATTGAAGACAGTTCTA
TCAGTCTTGACGAAGTTGATTACATAAATGCTCATGGAACGAGTACATCAGCTAATGACAAAAATGAAACTTCTGCAATT
AAATCTATTTTTAAAGACAGATCTTACCTTATTCCTGTAAGCTCTACTAAGTCGATGACTGGTCATCTCCTAGGAGGTTC
AGGAGGTATAGAAGCTGTTGCTTGTATACTTTCTTTGACACATAATTTTATCCCTCCTACAATTAACTACGTCAATCCAG
ATCCTGATTGTGATCTAGATTATGTACCAAATAATGCAAGAGAAGCTCGACTGGGAGTAGCTCTTTCTAATTCTTTCGGC
TTTGGTGGTCACAATGTTTGCCTTGCTTTTAGCAAAATGAATTGA

Upstream 100 bases:

>100_bases
GGAAGCATTTGATATTGAAATACCTGATGAAGCAGCTGAAGGCATTGCAACAGTTGGAGATGCAGTTAAATTCATCGAAG
AAAAAAAAGGTTAATTAAGA

Downstream 100 bases:

>100_bases
AGACAACCAATTCTGTATTTCCAAATTATCTTATTTTAAAAAAATGGTTGCTGCATCTGTTTCAATAGAATCACTCTGTG
TAAATAGTATAAGAATGCTT

Product: 3-oxoacyl-[acyl-carrier-protein] synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MPNFHRVVITGIGAVTPIGNNIDEYLLSLQKGANGVSGITLFDPVDHPCKFAAEVKNLQSQNFIEAKESKRWDRFSQFGV
IAAKQAFNDSGLEINEANASRIGVIIGSGVGGLLTMESQAQILSHKGPKRVSPFTVPMMIPNMATGLAAIALGAKGPSSS
VSTACAAGSNAIGDSFRLLQLGKADAMICGGAEASITPLGVAGFASAKALSFRNESPQTASRPFDAERDGFVIGEGSGIL
VLETLENAQKRDARIYGEIIGYGTTCDAHHITAPSPGGVGGAEAIKLAIEDSSISLDEVDYINAHGTSTSANDKNETSAI
KSIFKDRSYLIPVSSTKSMTGHLLGGSGGIEAVACILSLTHNFIPPTINYVNPDPDCDLDYVPNNAREARLGVALSNSFG
FGGHNVCLAFSKMN

Sequences:

>Translated_414_residues
MPNFHRVVITGIGAVTPIGNNIDEYLLSLQKGANGVSGITLFDPVDHPCKFAAEVKNLQSQNFIEAKESKRWDRFSQFGV
IAAKQAFNDSGLEINEANASRIGVIIGSGVGGLLTMESQAQILSHKGPKRVSPFTVPMMIPNMATGLAAIALGAKGPSSS
VSTACAAGSNAIGDSFRLLQLGKADAMICGGAEASITPLGVAGFASAKALSFRNESPQTASRPFDAERDGFVIGEGSGIL
VLETLENAQKRDARIYGEIIGYGTTCDAHHITAPSPGGVGGAEAIKLAIEDSSISLDEVDYINAHGTSTSANDKNETSAI
KSIFKDRSYLIPVSSTKSMTGHLLGGSGGIEAVACILSLTHNFIPPTINYVNPDPDCDLDYVPNNAREARLGVALSNSFG
FGGHNVCLAFSKMN
>Mature_413_residues
PNFHRVVITGIGAVTPIGNNIDEYLLSLQKGANGVSGITLFDPVDHPCKFAAEVKNLQSQNFIEAKESKRWDRFSQFGVI
AAKQAFNDSGLEINEANASRIGVIIGSGVGGLLTMESQAQILSHKGPKRVSPFTVPMMIPNMATGLAAIALGAKGPSSSV
STACAAGSNAIGDSFRLLQLGKADAMICGGAEASITPLGVAGFASAKALSFRNESPQTASRPFDAERDGFVIGEGSGILV
LETLENAQKRDARIYGEIIGYGTTCDAHHITAPSPGGVGGAEAIKLAIEDSSISLDEVDYINAHGTSTSANDKNETSAIK
SIFKDRSYLIPVSSTKSMTGHLLGGSGGIEAVACILSLTHNFIPPTINYVNPDPDCDLDYVPNNAREARLGVALSNSFGF
GGHNVCLAFSKMN

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=418, Percent_Identity=42.822966507177, Blast_Score=318, Evalue=8e-87,
Organism=Homo sapiens, GI223972627, Length=150, Percent_Identity=44.6666666666667, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI41872631, Length=427, Percent_Identity=24.1217798594848, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1787337, Length=410, Percent_Identity=49.0243902439024, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1788663, Length=414, Percent_Identity=35.9903381642512, Blast_Score=224, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI71983541, Length=416, Percent_Identity=32.2115384615385, Blast_Score=229, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=35.9848484848485, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI212642053, Length=423, Percent_Identity=26.4775413711584, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=278, Percent_Identity=25.8992805755396, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320904, Length=443, Percent_Identity=36.3431151241535, Blast_Score=260, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24644341, Length=419, Percent_Identity=41.7661097852029, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI221330659, Length=417, Percent_Identity=26.378896882494, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19920632, Length=417, Percent_Identity=26.378896882494, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24581345, Length=424, Percent_Identity=23.5849056603774, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43206; Mature: 43075

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNFHRVVITGIGAVTPIGNNIDEYLLSLQKGANGVSGITLFDPVDHPCKFAAEVKNLQS
CCCCEEEEEEECCEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCCC
QNFIEAKESKRWDRFSQFGVIAAKQAFNDSGLEINEANASRIGVIIGSGVGGLLTMESQA
CCCHHHHHHHHHHHHHHCCCEEHHHHCCCCCCEEECCCCCEEEEEEECCCCCEEEECHHH
QILSHKGPKRVSPFTVPMMIPNMATGLAAIALGAKGPSSSVSTACAAGSNAIGDSFRLLQ
HHHHCCCCCCCCCEEEEEECCCHHHHHHHEEECCCCCCCCHHHHHHCCCCCCCCCEEEEE
LGKADAMICGGAEASITPLGVAGFASAKALSFRNESPQTASRPFDAERDGFVIGEGSGIL
ECCCCEEEECCCCCCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCEEEECCCCEE
VLETLENAQKRDARIYGEIIGYGTTCDAHHITAPSPGGVGGAEAIKLAIEDSSISLDEVD
EEEEHHCHHHHHHHEEEHHEECCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCCCCCE
YINAHGTSTSANDKNETSAIKSIFKDRSYLIPVSSTKSMTGHLLGGSGGIEAVACILSLT
EEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHH
HNFIPPTINYVNPDPDCDLDYVPNNAREARLGVALSNSFGFGGHNVCLAFSKMN
HHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
PNFHRVVITGIGAVTPIGNNIDEYLLSLQKGANGVSGITLFDPVDHPCKFAAEVKNLQS
CCCEEEEEEECCEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCCC
QNFIEAKESKRWDRFSQFGVIAAKQAFNDSGLEINEANASRIGVIIGSGVGGLLTMESQA
CCCHHHHHHHHHHHHHHCCCEEHHHHCCCCCCEEECCCCCEEEEEEECCCCCEEEECHHH
QILSHKGPKRVSPFTVPMMIPNMATGLAAIALGAKGPSSSVSTACAAGSNAIGDSFRLLQ
HHHHCCCCCCCCCEEEEEECCCHHHHHHHEEECCCCCCCCHHHHHHCCCCCCCCCEEEEE
LGKADAMICGGAEASITPLGVAGFASAKALSFRNESPQTASRPFDAERDGFVIGEGSGIL
ECCCCEEEECCCCCCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCEEEECCCCEE
VLETLENAQKRDARIYGEIIGYGTTCDAHHITAPSPGGVGGAEAIKLAIEDSSISLDEVD
EEEEHHCHHHHHHHEEEHHEECCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCCCCCE
YINAHGTSTSANDKNETSAIKSIFKDRSYLIPVSSTKSMTGHLLGGSGGIEAVACILSLT
EEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHH
HNFIPPTINYVNPDPDCDLDYVPNNAREARLGVALSNSFGFGGHNVCLAFSKMN
HHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231; 11152607 [H]