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The map label for this gene is glmS [H]

Identifier: 78780084

GI number: 78780084

Start: 1587656

End: 1589551

Strand: Reverse

Name: glmS [H]

Synonym: PMT9312_1699

Alternate gene names: 78780084

Gene position: 1589551-1587656 (Counterclockwise)

Preceding gene: 78780085

Following gene: 78780082

Centisome position: 93.0

GC content: 33.12

Gene sequence:

>1896_bases
ATGTGTGGAATAGTTGCTGTCACTGGTTATAAAAAAGCTTTACCATTGTTAATGAATGGTTTAGAAAAACTTGAGTACAG
AGGTTACGATTCTGCAGGTATTGCAATAATAAATTCTGAAACAAATTCTATTATTTGTAACAAAGCAGAGGGCAAACTTA
AAAACTTAATAAATACTCTTAACGGTGAAAATATTCTTGGAACTGTGGGTATAGGACATACCCGATGGGCAACTCATGGA
AAACCTGAGGTTAAAAATGCCCATCCTCATATCGATAGTTCAGGAAATATAGCGGTTGTTCAAAATGGCATTATTGAGAA
TTTCCAAGACTTAAAAAATAAGTTAGAGAAAGAGGGCACCATTTTCAATTCTGATACAGATACGGAGGTAATTCCCCATC
TAATTGAAAAAGAATTAAATACATTAAGTAGACTTAATCTTGAGAATAATGGTTCAAAATTATTAGTGGCTGTTAGAAAT
GTAATATCTGATTTAGAAGGGTCTTATGCCTTGGCCGTTTTATGGTCTGGTGCTCCAACCTCTCTAGTAGTTGCAAGAAG
ACAAGCACCTTTAATTATTGGTTTGGGAGAAGGAGAATTCATTTGTGCTAGTGATACACCAGCTATTGCAAATTTTACAA
ACATTATCTTGCCTATGGAGGATGAAGAAATAGCTTTATTAACTCCTCTTGGAATAGAAATATATGACACAAACAACGAG
AGACAATATCGAAATCCAGTTTCTCTAAAAGTTTCAGACCAAATAATGGATAAGATGAATTTTAAACACTACATGTTAAA
AGAGATATATGATCAGCCAGGGACAGCAAAAAACTGGTTGGAAAATTATTTAATACAAAATTTAGAAGAGGGCCAATATG
AAATTAAATATCCATTTGATACAAAGTTTTTTGAATCAATTGAAAGAATTGAAATTATCGCTTGTGGTACAAGTAAACAT
GCTGCAATGGTGGGTAGCTTTTTATTAGAACAATTTGCAGGTATTCCTACAAATGTTTTTTATGCAAGCGAATTTCGATA
TTCACCACCTCCACTTCTGCCAAATACATTAACTATTGGAGTCACTCAATCTGGAGAAACTGCTGACACAATTGCAGCTA
TAGATATGGAAATTAAAAGACGGTCTTCGATTGAAGATAAAAACTTTAAACCCAATCTTATTGCAATAACAAATAGAAAA
GAGAGCTCTATAGGAAGGCAGGTTTCAAATGTAATTGATATCTGTGCAGGAATAGAAGTTGGAGTTGCGGCAACAAAAAC
TTTTTTTGCACAATTACTTTCTTTTTATGGATTAGCTATAAAATTTGCGCAAATTAAAGGTAGTCGAAGCTCAGATGAAA
TAGGTAAATTAATAACAGAACTTATAAAACTGCCTCCATTAATAGAAGATCTTTTAGAGCAGCATAATAAATCTTCTGAA
AAGTTAGCACATGATTTTTTTAATATTAAAGATGTTATCTTTTTAGGAAGAGGTATAAATTATCCTATTGCTCTTGAAGG
AGCGTTAAAACTCAAAGAAATTAGTTACATACATGCGGCTGGATATCCAGCTGGTGAAATGAAACATGGTCCAATAGCTT
TGTTAGATAAAAAAGTCCCTGTAATTTCTATTGCCTCCCCTGGTGAAGTTTTTGATAAAGTCATCAGTAATGCTCAAGAA
GCAAAAGCTAGAGATGCATATTTGATTGGGATTGCTCCTGAGTCTAATGGAACTGAAATCTTTGATTATTTAATGAAAGT
TCCTTCTTCTATTGAATGGATTTCACCTTTACTTAATATAGTGCCTTTACAATTATTGAGTTACCATATTGCAGCTCATA
GAGGACTTGACGTAGATCAACCAAGAAATTTAGCTAAAAGTGTAACTGTGGAATAA

Upstream 100 bases:

>100_bases
GTATGGGCCTAGCTTACTAACTTTATAGTGCAGTTTTAAGAGAGTCCATGATTTATTAAATACGCATTTTTTTTCAATAT
AATTAAAAAAAAATCAGCGT

Downstream 100 bases:

>100_bases
TTAGTTTCTTACAAACTTTTATCTTTTAAAATTTATAGATCTAAAAGTCCATTTGGAGGATTGATGATTAGAAAATTATT
TTTTATATCTACTAATGGAA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MCGIVAVTGYKKALPLLMNGLEKLEYRGYDSAGIAIINSETNSIICNKAEGKLKNLINTLNGENILGTVGIGHTRWATHG
KPEVKNAHPHIDSSGNIAVVQNGIIENFQDLKNKLEKEGTIFNSDTDTEVIPHLIEKELNTLSRLNLENNGSKLLVAVRN
VISDLEGSYALAVLWSGAPTSLVVARRQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDTNNE
RQYRNPVSLKVSDQIMDKMNFKHYMLKEIYDQPGTAKNWLENYLIQNLEEGQYEIKYPFDTKFFESIERIEIIACGTSKH
AAMVGSFLLEQFAGIPTNVFYASEFRYSPPPLLPNTLTIGVTQSGETADTIAAIDMEIKRRSSIEDKNFKPNLIAITNRK
ESSIGRQVSNVIDICAGIEVGVAATKTFFAQLLSFYGLAIKFAQIKGSRSSDEIGKLITELIKLPPLIEDLLEQHNKSSE
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVPVISIASPGEVFDKVISNAQE
AKARDAYLIGIAPESNGTEIFDYLMKVPSSIEWISPLLNIVPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE

Sequences:

>Translated_631_residues
MCGIVAVTGYKKALPLLMNGLEKLEYRGYDSAGIAIINSETNSIICNKAEGKLKNLINTLNGENILGTVGIGHTRWATHG
KPEVKNAHPHIDSSGNIAVVQNGIIENFQDLKNKLEKEGTIFNSDTDTEVIPHLIEKELNTLSRLNLENNGSKLLVAVRN
VISDLEGSYALAVLWSGAPTSLVVARRQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDTNNE
RQYRNPVSLKVSDQIMDKMNFKHYMLKEIYDQPGTAKNWLENYLIQNLEEGQYEIKYPFDTKFFESIERIEIIACGTSKH
AAMVGSFLLEQFAGIPTNVFYASEFRYSPPPLLPNTLTIGVTQSGETADTIAAIDMEIKRRSSIEDKNFKPNLIAITNRK
ESSIGRQVSNVIDICAGIEVGVAATKTFFAQLLSFYGLAIKFAQIKGSRSSDEIGKLITELIKLPPLIEDLLEQHNKSSE
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVPVISIASPGEVFDKVISNAQE
AKARDAYLIGIAPESNGTEIFDYLMKVPSSIEWISPLLNIVPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE
>Mature_631_residues
MCGIVAVTGYKKALPLLMNGLEKLEYRGYDSAGIAIINSETNSIICNKAEGKLKNLINTLNGENILGTVGIGHTRWATHG
KPEVKNAHPHIDSSGNIAVVQNGIIENFQDLKNKLEKEGTIFNSDTDTEVIPHLIEKELNTLSRLNLENNGSKLLVAVRN
VISDLEGSYALAVLWSGAPTSLVVARRQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDTNNE
RQYRNPVSLKVSDQIMDKMNFKHYMLKEIYDQPGTAKNWLENYLIQNLEEGQYEIKYPFDTKFFESIERIEIIACGTSKH
AAMVGSFLLEQFAGIPTNVFYASEFRYSPPPLLPNTLTIGVTQSGETADTIAAIDMEIKRRSSIEDKNFKPNLIAITNRK
ESSIGRQVSNVIDICAGIEVGVAATKTFFAQLLSFYGLAIKFAQIKGSRSSDEIGKLITELIKLPPLIEDLLEQHNKSSE
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVPVISIASPGEVFDKVISNAQE
AKARDAYLIGIAPESNGTEIFDYLMKVPSSIEWISPLLNIVPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=709, Percent_Identity=33.9915373765867, Blast_Score=344, Evalue=2e-94,
Organism=Homo sapiens, GI205277386, Length=699, Percent_Identity=32.9041487839771, Blast_Score=337, Evalue=2e-92,
Organism=Homo sapiens, GI29570798, Length=182, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790167, Length=635, Percent_Identity=41.7322834645669, Blast_Score=450, Evalue=1e-127,
Organism=Escherichia coli, GI1788651, Length=220, Percent_Identity=27.7272727272727, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87082251, Length=319, Percent_Identity=22.5705329153605, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17532899, Length=449, Percent_Identity=34.9665924276169, Blast_Score=239, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17532897, Length=449, Percent_Identity=34.9665924276169, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17539970, Length=446, Percent_Identity=34.304932735426, Blast_Score=238, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6322745, Length=446, Percent_Identity=32.9596412556054, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6323731, Length=457, Percent_Identity=27.3522975929978, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6323730, Length=210, Percent_Identity=38.0952380952381, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323958, Length=182, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357745, Length=710, Percent_Identity=34.5070422535211, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24659598, Length=202, Percent_Identity=26.2376237623762, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24659604, Length=182, Percent_Identity=26.3736263736264, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 69537; Mature: 69537

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVAVTGYKKALPLLMNGLEKLEYRGYDSAGIAIINSETNSIICNKAEGKLKNLINTL
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHC
NGENILGTVGIGHTRWATHGKPEVKNAHPHIDSSGNIAVVQNGIIENFQDLKNKLEKEGT
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCC
IFNSDTDTEVIPHLIEKELNTLSRLNLENNGSKLLVAVRNVISDLEGSYALAVLWSGAPT
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCEEEEEEECCCCC
SLVVARRQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDTNNE
EEEEEECCCCEEEECCCCCEEEECCCCCHHCCEEEEEECCCCCEEEEECCCEEEEECCCC
RQYRNPVSLKVSDQIMDKMNFKHYMLKEIYDQPGTAKNWLENYLIQNLEEGQYEIKYPFD
CCCCCCCEEEEHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCC
TKFFESIERIEIIACGTSKHAAMVGSFLLEQFAGIPTNVFYASEFRYSPPPLLPNTLTIG
CHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEE
VTQSGETADTIAAIDMEIKRRSSIEDKNFKPNLIAITNRKESSIGRQVSNVIDICAGIEV
EECCCCCCHHEEEHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHH
GVAATKTFFAQLLSFYGLAIKFAQIKGSRSSDEIGKLITELIKLPPLIEDLLEQHNKSSE
HHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHH
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVP
HHHHHHHCHHEEEEECCCCCCCEEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCC
VISIASPGEVFDKVISNAQEAKARDAYLIGIAPESNGTEIFDYLMKVPSSIEWISPLLNI
EEEECCCHHHHHHHHCCHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHH
VPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MCGIVAVTGYKKALPLLMNGLEKLEYRGYDSAGIAIINSETNSIICNKAEGKLKNLINTL
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHC
NGENILGTVGIGHTRWATHGKPEVKNAHPHIDSSGNIAVVQNGIIENFQDLKNKLEKEGT
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCC
IFNSDTDTEVIPHLIEKELNTLSRLNLENNGSKLLVAVRNVISDLEGSYALAVLWSGAPT
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCEEEEEEECCCCC
SLVVARRQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDTNNE
EEEEEECCCCEEEECCCCCEEEECCCCCHHCCEEEEEECCCCCEEEEECCCEEEEECCCC
RQYRNPVSLKVSDQIMDKMNFKHYMLKEIYDQPGTAKNWLENYLIQNLEEGQYEIKYPFD
CCCCCCCEEEEHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCC
TKFFESIERIEIIACGTSKHAAMVGSFLLEQFAGIPTNVFYASEFRYSPPPLLPNTLTIG
CHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEE
VTQSGETADTIAAIDMEIKRRSSIEDKNFKPNLIAITNRKESSIGRQVSNVIDICAGIEV
EECCCCCCHHEEEHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHH
GVAATKTFFAQLLSFYGLAIKFAQIKGSRSSDEIGKLITELIKLPPLIEDLLEQHNKSSE
HHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHH
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVP
HHHHHHHCHHEEEEECCCCCCCEEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCC
VISIASPGEVFDKVISNAQEAKARDAYLIGIAPESNGTEIFDYLMKVPSSIEWISPLLNI
EEEECCCHHHHHHHHCCHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHH
VPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]