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The map label for this gene is dapL [H]

Identifier: 78779976

GI number: 78779976

Start: 1489560

End: 1490786

Strand: Reverse

Name: dapL [H]

Synonym: PMT9312_1592

Alternate gene names: 78779976

Gene position: 1490786-1489560 (Counterclockwise)

Preceding gene: 78779979

Following gene: 78779975

Centisome position: 87.22

GC content: 34.64

Gene sequence:

>1227_bases
GTGGTTCAAGTAAACGAAAATTATTTAAAACTTAAAGCAGGCTATTTATTTCCTGAAATTGCGAAAAGGGTGAAAATATA
TTCTCAATCAAATAAGAGTGCTGAAATTATTAAGCTTGGCATAGGAGATGTTACAGAACCATTACCTAGAGCATGCATAG
ATGCTATGAGTAAAGCTTTAGATGATATGGGAACAGCCGAAGGTTTTAGAGGTTATGGACCAGAACAAGGTTATTCTTGG
CTCAGAGAAAAAATATCTGAGCATGATTTTATTTCGAGAGGCTGTCAAATATTACCTGAAGAAATCTTTGTGTCAGATGG
GTCTAAATGCGATAGTAGCAATATTTTAGATATTCTTGGCAAAGATAATTCAATTGCTGTAACAGATCCTGTTTACCCTG
TTTATGTAGATAGTAACGTTATGACAGGCAGAACTGGAGATGCTCTTGAAAATGGAACTTATCAAGGGTTGACATATCTT
GCAATAAACGAGGGAAATAACTTTCTGCCAGAACTACCTCAAAAAAAAGTTGATATTTTATATCTTTGTTTTCCTAATAA
TCCGACTGGAGCAACGATTACTAAAGAAGAATTGAAAAAGTGGGTTGACTATGCTCTTCAAAACAAATCTTTAATACTTT
TTGATGCGGCTTATGAAGCATTTATTCAAGATAATGATATTCCACATTCAATATATGAGATTGAGGGAGCAAAGGATTGT
GCTATTGAATTTAGATCTTTTTCAAAGAATGCAGGATTCACTGGAGTTCGATGTGCTTTTACCGTAATACCTAAAAATCT
CAAAGGTTTGAGCTCAACAAATGAGGAAATAGACTTATGGCCTCTTTGGAATAGGCGACAATCTACAAAGTTCAATGGAG
TAAGTTATGTGGTTCAGAGAGGAGCAGAGGCTGTTTATTCTCTTGAAGGGAAGAAAGAGGTAAGAGGTTTAATTGATTTT
TATATGGAAAATGCAAAAATCATGAAAAATAAACTTCAGACTGCAGGATATAAAGTTTATGGTGGGGACAATGCTCCTTA
TATCTGGATTAAAGTTCCTGATCAAATGACATCTTGGAACTTTTTTGATTTCCTTCTTCAAAACGTTAGTGTTGTAGGTA
CACCTGGGAGCGGATTTGGATTATCAGGAGAGGGTTATTTTCGTTTGTCAGCATTTAACTCACGATCAAACGTTCTTGAT
GCAATGGAAAGAATAATTAATATATAA

Upstream 100 bases:

>100_bases
TATCTCTTATATTAATCATAACTACAATAATATTAACATCTAATCACCACTTAAGCACGTTGATCCATTATTCTAATATT
GGTTAAATTTTTTATTTAAA

Downstream 100 bases:

>100_bases
TTATTAGTACTATCTAGATTCTAGAAAATTTAATGTTATCTATAAAGTTAGAACAAAGTGTAAGTAATAATTCAGCAGTG
ATTGAAAAGAAACCTGCTGA

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MVQVNENYLKLKAGYLFPEIAKRVKIYSQSNKSAEIIKLGIGDVTEPLPRACIDAMSKALDDMGTAEGFRGYGPEQGYSW
LREKISEHDFISRGCQILPEEIFVSDGSKCDSSNILDILGKDNSIAVTDPVYPVYVDSNVMTGRTGDALENGTYQGLTYL
AINEGNNFLPELPQKKVDILYLCFPNNPTGATITKEELKKWVDYALQNKSLILFDAAYEAFIQDNDIPHSIYEIEGAKDC
AIEFRSFSKNAGFTGVRCAFTVIPKNLKGLSSTNEEIDLWPLWNRRQSTKFNGVSYVVQRGAEAVYSLEGKKEVRGLIDF
YMENAKIMKNKLQTAGYKVYGGDNAPYIWIKVPDQMTSWNFFDFLLQNVSVVGTPGSGFGLSGEGYFRLSAFNSRSNVLD
AMERIINI

Sequences:

>Translated_408_residues
MVQVNENYLKLKAGYLFPEIAKRVKIYSQSNKSAEIIKLGIGDVTEPLPRACIDAMSKALDDMGTAEGFRGYGPEQGYSW
LREKISEHDFISRGCQILPEEIFVSDGSKCDSSNILDILGKDNSIAVTDPVYPVYVDSNVMTGRTGDALENGTYQGLTYL
AINEGNNFLPELPQKKVDILYLCFPNNPTGATITKEELKKWVDYALQNKSLILFDAAYEAFIQDNDIPHSIYEIEGAKDC
AIEFRSFSKNAGFTGVRCAFTVIPKNLKGLSSTNEEIDLWPLWNRRQSTKFNGVSYVVQRGAEAVYSLEGKKEVRGLIDF
YMENAKIMKNKLQTAGYKVYGGDNAPYIWIKVPDQMTSWNFFDFLLQNVSVVGTPGSGFGLSGEGYFRLSAFNSRSNVLD
AMERIINI
>Mature_408_residues
MVQVNENYLKLKAGYLFPEIAKRVKIYSQSNKSAEIIKLGIGDVTEPLPRACIDAMSKALDDMGTAEGFRGYGPEQGYSW
LREKISEHDFISRGCQILPEEIFVSDGSKCDSSNILDILGKDNSIAVTDPVYPVYVDSNVMTGRTGDALENGTYQGLTYL
AINEGNNFLPELPQKKVDILYLCFPNNPTGATITKEELKKWVDYALQNKSLILFDAAYEAFIQDNDIPHSIYEIEGAKDC
AIEFRSFSKNAGFTGVRCAFTVIPKNLKGLSSTNEEIDLWPLWNRRQSTKFNGVSYVVQRGAEAVYSLEGKKEVRGLIDF
YMENAKIMKNKLQTAGYKVYGGDNAPYIWIKVPDQMTSWNFFDFLLQNVSVVGTPGSGFGLSGEGYFRLSAFNSRSNVLD
AMERIINI

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=390, Percent_Identity=25.6410256410256, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 45615; Mature: 45615

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQVNENYLKLKAGYLFPEIAKRVKIYSQSNKSAEIIKLGIGDVTEPLPRACIDAMSKAL
CEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
DDMGTAEGFRGYGPEQGYSWLREKISEHDFISRGCQILPEEIFVSDGSKCDSSNILDILG
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCCCCEEEEC
KDNSIAVTDPVYPVYVDSNVMTGRTGDALENGTYQGLTYLAINEGNNFLPELPQKKVDIL
CCCCEEEECCEEEEEECCCEEECCCCCHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEE
YLCFPNNPTGATITKEELKKWVDYALQNKSLILFDAAYEAFIQDNDIPHSIYEIEGAKDC
EEEECCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCEEEECCCHHH
AIEFRSFSKNAGFTGVRCAFTVIPKNLKGLSSTNEEIDLWPLWNRRQSTKFNGVSYVVQR
HHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
GAEAVYSLEGKKEVRGLIDFYMENAKIMKNKLQTAGYKVYGGDNAPYIWIKVPDQMTSWN
CCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCCH
FFDFLLQNVSVVGTPGSGFGLSGEGYFRLSAFNSRSNVLDAMERIINI
HHHHHHHCCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVQVNENYLKLKAGYLFPEIAKRVKIYSQSNKSAEIIKLGIGDVTEPLPRACIDAMSKAL
CEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
DDMGTAEGFRGYGPEQGYSWLREKISEHDFISRGCQILPEEIFVSDGSKCDSSNILDILG
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCCCCEEEEC
KDNSIAVTDPVYPVYVDSNVMTGRTGDALENGTYQGLTYLAINEGNNFLPELPQKKVDIL
CCCCEEEECCEEEEEECCCEEECCCCCHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCEE
YLCFPNNPTGATITKEELKKWVDYALQNKSLILFDAAYEAFIQDNDIPHSIYEIEGAKDC
EEEECCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCEEEECCCHHH
AIEFRSFSKNAGFTGVRCAFTVIPKNLKGLSSTNEEIDLWPLWNRRQSTKFNGVSYVVQR
HHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
GAEAVYSLEGKKEVRGLIDFYMENAKIMKNKLQTAGYKVYGGDNAPYIWIKVPDQMTSWN
CCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCCH
FFDFLLQNVSVVGTPGSGFGLSGEGYFRLSAFNSRSNVLDAMERIINI
HHHHHHHCCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA