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The map label for this gene is degP [C]

Identifier: 78779967

GI number: 78779967

Start: 1478941

End: 1480071

Strand: Reverse

Name: degP [C]

Synonym: PMT9312_1583

Alternate gene names: 78779967

Gene position: 1480071-1478941 (Counterclockwise)

Preceding gene: 78779972

Following gene: 78779966

Centisome position: 86.59

GC content: 35.9

Gene sequence:

>1131_bases
ATGAAGTTTCTCAAGATTAAATTAATTAATTTAATCCAAATATTCATTATTGTTTGTTTTTGTTTAGTTAATTTCTCTCA
AAGAGCTGAAGTTTTAGCCTTGACTTCTTCTGATAGTCACAATTTCGTATCATCTGCGGTTAGAAATGTTGGACCTGCAG
TGGTAAAAATTGATACTGAGCGATTCGTTGAGAGGCAACAATTTGATCCAACTTTACTGGACCCTTTATTGAGGGATTTG
CTTGGGGAGCAAGGAATTACACCTGAGAGAGAGAGAGGTCAAGGTTCTGGAGTAATTATTAATGAGAATGGTTTGGTTCT
TACTAATGCTCATGTCGTAGACAGAGTTGATGATGTTTTAGTGACTTTGGCAGATGGAAGTATTTGCGATGGCCAAGTTT
TGGGAACAGATGCAGTAACTGACCTGGCTTTAGTAAAAATTGAGGAATCTACATTTTCTAGTTTTGCTCCCCTTGGAAAT
TCTGAAGATCTTCAAGTTGGAGATTGGGCAATAGCACTAGGTACTCCCTATGGTCTAGAAAAAACAGTTACCTTAGGAAT
TGTAAGTAGTTTACATAGGGATATTAATAGTCTAGGGTTTTCAGATAAAAGGCTTGATCTTATTCAGACTGATGCGGCAA
TAAATCCTGGGAATTCTGGAGGACCACTTATTAATTCTAATGGTGAAGTAATAGGAATCAATACATTGGTAAGAAGTGGC
CCTGGAGCTGGTCTAGGTTTCGCAATACCTATTAATCTAGCTAAAAGTGTTTCTGATCAGCTTCTCAATAATGGTGAAGT
TATTCATCCATATTTAGGGGTTCAATTAATTTCTTTGAATCCTAGAATTGCTAAAGAACATAATCAAGACCCCAATTCAT
TAGTCCAATTACCTGAACGAAATGGGGCTCTTATTCAATCAGTCATACCTAATAGTCCTGCTGAAAAAGCTGGTTTAAGA
AGAGGTGATTTAGTTATAGCAGCCGAAAACATCTCTATAGAAGAACCTAAAGCTTTGCTAGATGAAGTTGAAAAAGCTCA
GATAGGAAAAGTATTCCTTTTAAATGTTTTAAGAGATAATAAAGAGATAAAGATAAATATCAAACCAGAACCTCTACCAG
GTTTGACATAA

Upstream 100 bases:

>100_bases
ATTCAAAAATTTATATTTTTATGGATGTAAACAAAAAAACAACAAATATATATTTCTTCAATTAGATTTACTCAATAAAT
TTTAAAAAACTATTAAATAA

Downstream 100 bases:

>100_bases
ATCGCTCATTGAAATTTAATAATCTATAACAATAGAAAAAAAGATTTTGAATTCACAAACTCAAATGAAACAAATAGTTG
CTGAAGCAGCAATTGAGGAA

Product: trypsin-like serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MKFLKIKLINLIQIFIIVCFCLVNFSQRAEVLALTSSDSHNFVSSAVRNVGPAVVKIDTERFVERQQFDPTLLDPLLRDL
LGEQGITPERERGQGSGVIINENGLVLTNAHVVDRVDDVLVTLADGSICDGQVLGTDAVTDLALVKIEESTFSSFAPLGN
SEDLQVGDWAIALGTPYGLEKTVTLGIVSSLHRDINSLGFSDKRLDLIQTDAAINPGNSGGPLINSNGEVIGINTLVRSG
PGAGLGFAIPINLAKSVSDQLLNNGEVIHPYLGVQLISLNPRIAKEHNQDPNSLVQLPERNGALIQSVIPNSPAEKAGLR
RGDLVIAAENISIEEPKALLDEVEKAQIGKVFLLNVLRDNKEIKINIKPEPLPGLT

Sequences:

>Translated_376_residues
MKFLKIKLINLIQIFIIVCFCLVNFSQRAEVLALTSSDSHNFVSSAVRNVGPAVVKIDTERFVERQQFDPTLLDPLLRDL
LGEQGITPERERGQGSGVIINENGLVLTNAHVVDRVDDVLVTLADGSICDGQVLGTDAVTDLALVKIEESTFSSFAPLGN
SEDLQVGDWAIALGTPYGLEKTVTLGIVSSLHRDINSLGFSDKRLDLIQTDAAINPGNSGGPLINSNGEVIGINTLVRSG
PGAGLGFAIPINLAKSVSDQLLNNGEVIHPYLGVQLISLNPRIAKEHNQDPNSLVQLPERNGALIQSVIPNSPAEKAGLR
RGDLVIAAENISIEEPKALLDEVEKAQIGKVFLLNVLRDNKEIKINIKPEPLPGLT
>Mature_376_residues
MKFLKIKLINLIQIFIIVCFCLVNFSQRAEVLALTSSDSHNFVSSAVRNVGPAVVKIDTERFVERQQFDPTLLDPLLRDL
LGEQGITPERERGQGSGVIINENGLVLTNAHVVDRVDDVLVTLADGSICDGQVLGTDAVTDLALVKIEESTFSSFAPLGN
SEDLQVGDWAIALGTPYGLEKTVTLGIVSSLHRDINSLGFSDKRLDLIQTDAAINPGNSGGPLINSNGEVIGINTLVRSG
PGAGLGFAIPINLAKSVSDQLLNNGEVIHPYLGVQLISLNPRIAKEHNQDPNSLVQLPERNGALIQSVIPNSPAEKAGLR
RGDLVIAAENISIEEPKALLDEVEKAQIGKVFLLNVLRDNKEIKINIKPEPLPGLT

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=340, Percent_Identity=35, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI7019477, Length=343, Percent_Identity=33.2361516034985, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI22129776, Length=345, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI24308541, Length=340, Percent_Identity=32.9411764705882, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1786356, Length=278, Percent_Identity=39.9280575539568, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1789629, Length=320, Percent_Identity=36.875, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789630, Length=288, Percent_Identity=35.4166666666667, Blast_Score=167, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24646839, Length=348, Percent_Identity=33.6206896551724, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 40397; Mature: 40397

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLKIKLINLIQIFIIVCFCLVNFSQRAEVLALTSSDSHNFVSSAVRNVGPAVVKIDTE
CCEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECHH
RFVERQQFDPTLLDPLLRDLLGEQGITPERERGQGSGVIINENGLVLTNAHVVDRVDDVL
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHCCCCCEEEECCCCEEEECCHHHHHHHHEE
VTLADGSICDGQVLGTDAVTDLALVKIEESTFSSFAPLGNSEDLQVGDWAIALGTPYGLE
EEECCCCCCCCEEECCHHHCEEEEEEEECHHHHHHCCCCCCCCCEECCEEEEECCCCCCC
KTVTLGIVSSLHRDINSLGFSDKRLDLIQTDAAINPGNSGGPLINSNGEVIGINTLVRSG
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEECCCCCEEEEEHHHHCC
PGAGLGFAIPINLAKSVSDQLLNNGEVIHPYLGVQLISLNPRIAKEHNQDPNSLVQLPER
CCCCCEEEEEHHHHHHHHHHHHCCCCEEEHHHCEEEEECCCHHHHHCCCCHHHHHCCCCC
NGALIQSVIPNSPAEKAGLRRGDLVIAAENISIEEPKALLDEVEKAQIGKVFLLNVLRDN
CCCEEHHHCCCCCHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHEEEHHHCCC
KEIKINIKPEPLPGLT
CEEEEEECCCCCCCCC
>Mature Secondary Structure
MKFLKIKLINLIQIFIIVCFCLVNFSQRAEVLALTSSDSHNFVSSAVRNVGPAVVKIDTE
CCEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECHH
RFVERQQFDPTLLDPLLRDLLGEQGITPERERGQGSGVIINENGLVLTNAHVVDRVDDVL
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHCCCCCEEEECCCCEEEECCHHHHHHHHEE
VTLADGSICDGQVLGTDAVTDLALVKIEESTFSSFAPLGNSEDLQVGDWAIALGTPYGLE
EEECCCCCCCCEEECCHHHCEEEEEEEECHHHHHHCCCCCCCCCEECCEEEEECCCCCCC
KTVTLGIVSSLHRDINSLGFSDKRLDLIQTDAAINPGNSGGPLINSNGEVIGINTLVRSG
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEECCCCCEEEEEHHHHCC
PGAGLGFAIPINLAKSVSDQLLNNGEVIHPYLGVQLISLNPRIAKEHNQDPNSLVQLPER
CCCCCEEEEEHHHHHHHHHHHHCCCCEEEHHHCEEEEECCCHHHHHCCCCHHHHHCCCCC
NGALIQSVIPNSPAEKAGLRRGDLVIAAENISIEEPKALLDEVEKAQIGKVFLLNVLRDN
CCCEEHHHCCCCCHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHEEEHHHCCC
KEIKINIKPEPLPGLT
CEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA