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The map label for this gene is rpiA

Identifier: 78779966

GI number: 78779966

Start: 1478181

End: 1478894

Strand: Reverse

Name: rpiA

Synonym: PMT9312_1582

Alternate gene names: 78779966

Gene position: 1478894-1478181 (Counterclockwise)

Preceding gene: 78779967

Following gene: 78779964

Centisome position: 86.53

GC content: 35.43

Gene sequence:

>714_bases
TTGAATTCACAAACTCAAATGAAACAAATAGTTGCTGAAGCAGCAATTGAGGAAGTAAAGAGTGACATGATTCTCGGATT
AGGATCTGGTTCTACAGCTGTGCTTATGATAAAAAGCCTTGCTGATGCAATTCGTTCTGGAAAACTGCAAAATATAAAAG
GTGTTGCAACTTCCTTTCAATCAGAAGTTTTAGCGCTCGAACTGGATATCCCACTTATTGATTTGGCTTCTGTTTCTCAA
ATCGATTTAGCTATTGATGGAGCAGATGAAGTTGATCCGGGTTTTCAATTAATTAAAGGGGGAGGAGCATGTCATGTTAG
AGAAAAGTTAGTGGCATCTAAAGCTAATCAATTGTTGATTGTTGTTGACGAAACGAAACTCGTACGAAAATTAAATCAAT
CTTTTCCTTTACCTGTAGAAGTTCTTCCAAATGCTTGGAAACAAGTTCAGGAAGTGATTTCAGAAATGAATGGCATTTCT
ACTTTAAGAATGGCGACTAAAAAAGCTGGCCCAGTTGTTACTGATCAGGGCAATCTAATCCTAGATGTATTGTTTAATGA
TGGTATTAAGAATCCAAAAGATATTGAAAAGAGTATTAATAATATTCCAGGAGTATTAGAAAATGGATTATTCATTGACC
TTACAGACAAAGTATTGGTTGGTAAAATTGAAAACAATATTCCTGTTGCTTACTCTCCCGCAAAAGTTGGCTAA

Upstream 100 bases:

>100_bases
AATAAAGAGATAAAGATAAATATCAAACCAGAACCTCTACCAGGTTTGACATAAATCGCTCATTGAAATTTAATAATCTA
TAACAATAGAAAAAAAGATT

Downstream 100 bases:

>100_bases
TCTTCAAATCTTATTTTTACTGAGTTGGCATGACTATGTAAGCCCTCACTCTCAGCAAGATTAATAATATCGAGACTGTT
GACTTTTAAACTTTCTTCAT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNSQTQMKQIVAEAAIEEVKSDMILGLGSGSTAVLMIKSLADAIRSGKLQNIKGVATSFQSEVLALELDIPLIDLASVSQ
IDLAIDGADEVDPGFQLIKGGGACHVREKLVASKANQLLIVVDETKLVRKLNQSFPLPVEVLPNAWKQVQEVISEMNGIS
TLRMATKKAGPVVTDQGNLILDVLFNDGIKNPKDIEKSINNIPGVLENGLFIDLTDKVLVGKIENNIPVAYSPAKVG

Sequences:

>Translated_237_residues
MNSQTQMKQIVAEAAIEEVKSDMILGLGSGSTAVLMIKSLADAIRSGKLQNIKGVATSFQSEVLALELDIPLIDLASVSQ
IDLAIDGADEVDPGFQLIKGGGACHVREKLVASKANQLLIVVDETKLVRKLNQSFPLPVEVLPNAWKQVQEVISEMNGIS
TLRMATKKAGPVVTDQGNLILDVLFNDGIKNPKDIEKSINNIPGVLENGLFIDLTDKVLVGKIENNIPVAYSPAKVG
>Mature_237_residues
MNSQTQMKQIVAEAAIEEVKSDMILGLGSGSTAVLMIKSLADAIRSGKLQNIKGVATSFQSEVLALELDIPLIDLASVSQ
IDLAIDGADEVDPGFQLIKGGGACHVREKLVASKANQLLIVVDETKLVRKLNQSFPLPVEVLPNAWKQVQEVISEMNGIS
TLRMATKKAGPVVTDQGNLILDVLFNDGIKNPKDIEKSINNIPGVLENGLFIDLTDKVLVGKIENNIPVAYSPAKVG

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=237, Percent_Identity=38.8185654008439, Blast_Score=163, Evalue=1e-40,
Organism=Escherichia coli, GI1789280, Length=221, Percent_Identity=38.9140271493213, Blast_Score=121, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17551758, Length=227, Percent_Identity=37.8854625550661, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6324669, Length=241, Percent_Identity=34.0248962655602, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281364072, Length=211, Percent_Identity=40.7582938388626, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_PROM9 (Q318Q3)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_398078.1
- ProteinModelPortal:   Q318Q3
- SMR:   Q318Q3
- STRING:   Q318Q3
- GeneID:   3766399
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_1582
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- BioCyc:   PMAR74546:PMT9312_1582-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25335; Mature: 25335

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQTQMKQIVAEAAIEEVKSDMILGLGSGSTAVLMIKSLADAIRSGKLQNIKGVATSFQ
CCCHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SEVLALELDIPLIDLASVSQIDLAIDGADEVDPGFQLIKGGGACHVREKLVASKANQLLI
CCEEEEEECCCEECCCCCCEEEEEECCCCCCCCCHHEEECCCCHHHHHHHHHCCCCCEEE
VVDETKLVRKLNQSFPLPVEVLPNAWKQVQEVISEMNGISTLRMATKKAGPVVTDQGNLI
EECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCEE
LDVLFNDGIKNPKDIEKSINNIPGVLENGLFIDLTDKVLVGKIENNIPVAYSPAKVG
EEEEECCCCCCHHHHHHHHHHCCHHHHCCEEEEECCCEEEEEECCCCCEEECCCCCC
>Mature Secondary Structure
MNSQTQMKQIVAEAAIEEVKSDMILGLGSGSTAVLMIKSLADAIRSGKLQNIKGVATSFQ
CCCHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SEVLALELDIPLIDLASVSQIDLAIDGADEVDPGFQLIKGGGACHVREKLVASKANQLLI
CCEEEEEECCCEECCCCCCEEEEEECCCCCCCCCHHEEECCCCHHHHHHHHHCCCCCEEE
VVDETKLVRKLNQSFPLPVEVLPNAWKQVQEVISEMNGISTLRMATKKAGPVVTDQGNLI
EECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCEE
LDVLFNDGIKNPKDIEKSINNIPGVLENGLFIDLTDKVLVGKIENNIPVAYSPAKVG
EEEEECCCCCCHHHHHHHHHHCCHHHHCCEEEEECCCEEEEEECCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA