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The map label for this gene is prmA

Identifier: 78779835

GI number: 78779835

Start: 1362359

End: 1363270

Strand: Reverse

Name: prmA

Synonym: PMT9312_1451

Alternate gene names: 78779835

Gene position: 1363270-1362359 (Counterclockwise)

Preceding gene: 78779836

Following gene: 78779834

Centisome position: 79.76

GC content: 28.51

Gene sequence:

>912_bases
ATGGCGAGTAAAGATTGGTATAAACTAAACTTTCAGATAGAAAGTGATTTAGAAGAAATTATTATTTGGAAATTAAATGA
GCTAGGAATATTCAGTTTTTCATTTGAATATTTGATAAAAACTGAAAATAAAAAAGAAGTGAATATATGGCTTCCAATTA
ATGAATGGGACGAGAGTTCCAGAAGTGATTTTGAAAAAATAATTTGCAAACTTCTCAACATTAATGACTCTATTAATAAA
TTTTTTGACTGGAGTGTTATTAAAGAAGAGGATTGGTTAACAAGCTGGAAGAAATATTGGGCCCCTGAATTAGTAGGAAA
TCATTTTCTAATATTACCTTGTTGGATAAATCTAAATGAAGAATTTAATGATAAACAAATCATAAAAATTGACCCTGGAG
CAGCCTTTGGTACTGGCAGTCATCCCTCGACTTATCTATGCTTAGAAAAAATGGAGAAAATTTTATTATCTGATAAAAAG
GTATTAGATATTGGGAGTGGCAGCGGTATTTTGAGCATTGCTGCAAGATTATTAGGAGCTAAAGAGGTTTGTGCAATTGA
TAATGATTATCTAGCTATAAATTCAACTAACTCTAATTTTCAACTAAATTTCGGAAATTTAAATAACTTAAACACATATT
TGGGATCTTTTAATGAGGTAATTTTAAAACATCAACTCAAAAAAATCGATTTTGTTGTATGCAATATTCTCGCTGAAGTA
ATAAAAGAAATGATTCCGAATATTTATAAGTGTTTGAGAAATAATGGCGAAGTCATTTTCAGTGGAATTCTGAATTCACA
AAAAGATGAAATTATAAAAATATTAATTCAAAATAACTTGAAATTATTGGATGTATCATCTAGAAAAGATTGGGCTTGTA
TTTATGCGCAAAAAGCAAAGAATCTAACCTAA

Upstream 100 bases:

>100_bases
TGATGATCCAATACCTAATAAGTTGCTTGACACCATTATTGAAGTAGAGGGAATTACTAGCGCTAATCCAGTTACTTTAT
AAAAAGTCTGACTAACTATA

Downstream 100 bases:

>100_bases
GTATAAGTTTTTCTTATTGATACTCTTTAATACATTTTATTGTGTCATTTTTTACGTCAAAATCCCCCATATCGACCTAA
TCAATGTTAAAAATGTATTT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MASKDWYKLNFQIESDLEEIIIWKLNELGIFSFSFEYLIKTENKKEVNIWLPINEWDESSRSDFEKIICKLLNINDSINK
FFDWSVIKEEDWLTSWKKYWAPELVGNHFLILPCWINLNEEFNDKQIIKIDPGAAFGTGSHPSTYLCLEKMEKILLSDKK
VLDIGSGSGILSIAARLLGAKEVCAIDNDYLAINSTNSNFQLNFGNLNNLNTYLGSFNEVILKHQLKKIDFVVCNILAEV
IKEMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQNNLKLLDVSSRKDWACIYAQKAKNLT

Sequences:

>Translated_303_residues
MASKDWYKLNFQIESDLEEIIIWKLNELGIFSFSFEYLIKTENKKEVNIWLPINEWDESSRSDFEKIICKLLNINDSINK
FFDWSVIKEEDWLTSWKKYWAPELVGNHFLILPCWINLNEEFNDKQIIKIDPGAAFGTGSHPSTYLCLEKMEKILLSDKK
VLDIGSGSGILSIAARLLGAKEVCAIDNDYLAINSTNSNFQLNFGNLNNLNTYLGSFNEVILKHQLKKIDFVVCNILAEV
IKEMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQNNLKLLDVSSRKDWACIYAQKAKNLT
>Mature_302_residues
ASKDWYKLNFQIESDLEEIIIWKLNELGIFSFSFEYLIKTENKKEVNIWLPINEWDESSRSDFEKIICKLLNINDSINKF
FDWSVIKEEDWLTSWKKYWAPELVGNHFLILPCWINLNEEFNDKQIIKIDPGAAFGTGSHPSTYLCLEKMEKILLSDKKV
LDIGSGSGILSIAARLLGAKEVCAIDNDYLAINSTNSNFQLNFGNLNNLNTYLGSFNEVILKHQLKKIDFVVCNILAEVI
KEMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQNNLKLLDVSSRKDWACIYAQKAKNLT

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=212, Percent_Identity=34.4339622641509, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_PROM9 (Q319D4)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_397947.1
- ProteinModelPortal:   Q319D4
- SMR:   Q319D4
- STRING:   Q319D4
- GeneID:   3766267
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_1451
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   MSFGTGY
- ProtClustDB:   PRK00517
- BioCyc:   PMAR74546:PMT9312_1451-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34947; Mature: 34815

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKDWYKLNFQIESDLEEIIIWKLNELGIFSFSFEYLIKTENKKEVNIWLPINEWDESS
CCCCCEEEEEEEECCCCCEEEEEEECCCEEEEEEEEEEEECCCCCEEEEEEECCCCCCCH
RSDFEKIICKLLNINDSINKFFDWSVIKEEDWLTSWKKYWAPELVGNHFLILPCWINLNE
HHHHHHHHHHHHCCCCHHHHHCCCEEECCHHHHHHHHHHCCHHHHCCCEEEEEEEEECCC
EFNDKQIIKIDPGAAFGTGSHPSTYLCLEKMEKILLSDKKVLDIGSGSGILSIAARLLGA
CCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCC
KEVCAIDNDYLAINSTNSNFQLNFGNLNNLNTYLGSFNEVILKHQLKKIDFVVCNILAEV
CCEEEECCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKEMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQNNLKLLDVSSRKDWACIYAQKAK
HHHHHHHHHHHHHCCCCEEEEEHHCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCC
NLT
CCC
>Mature Secondary Structure 
ASKDWYKLNFQIESDLEEIIIWKLNELGIFSFSFEYLIKTENKKEVNIWLPINEWDESS
CCCCEEEEEEEECCCCCEEEEEEECCCEEEEEEEEEEEECCCCCEEEEEEECCCCCCCH
RSDFEKIICKLLNINDSINKFFDWSVIKEEDWLTSWKKYWAPELVGNHFLILPCWINLNE
HHHHHHHHHHHHCCCCHHHHHCCCEEECCHHHHHHHHHHCCHHHHCCCEEEEEEEEECCC
EFNDKQIIKIDPGAAFGTGSHPSTYLCLEKMEKILLSDKKVLDIGSGSGILSIAARLLGA
CCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCC
KEVCAIDNDYLAINSTNSNFQLNFGNLNNLNTYLGSFNEVILKHQLKKIDFVVCNILAEV
CCEEEECCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKEMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQNNLKLLDVSSRKDWACIYAQKAK
HHHHHHHHHHHHHCCCCEEEEEHHCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCC
NLT
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA