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The map label for this gene is cysS

Identifier: 78779620

GI number: 78779620

Start: 1152363

End: 1153832

Strand: Direct

Name: cysS

Synonym: PMT9312_1237

Alternate gene names: 78779620

Gene position: 1152363-1153832 (Clockwise)

Preceding gene: 78779619

Following gene: 78779621

Centisome position: 67.42

GC content: 31.09

Gene sequence:

>1470_bases
ATGATCAAACTTTTTAATACTTTAAGCAAAAGAGTTGAGGTTTTTAAACCTATTGATGATGTAGTAAAAATCTATTGTTG
TGGAGTAACTGTTTATGACTTATGTCATCTTGGTCATGCCAGAAGTTATATAGCTTGGGATGTATTGAGAAGATTTTTAA
TTTACAGTGATTTCAAAGTGAAGTATGTTCAAAATTTTACAGATATTGATGACAAAATCTTAAAAAGAGCGAAAGAAGAA
AGTAGTTCAATGAAGGAAGTATCTGAAAAGAATATTATTGAATTTCATAAGGATATGGATTCTTTAGGGATAATGCGTCC
GGATAGTATGCCAAGAGCAACGAATCATATATGCAATATCTGCTCCTTCATAACAATCCTTGAGGACAAAGGTTATGCAT
ACTCTAGGGATGGAGATGTTTATTATTCTGTTTTTAAAAATAAAAATTATGGAAAGCTAAGTAATCAAAATATACAAGAA
CAAAATATCAATAAGCAAGGAAGAATGGCTAATGAGGAAAATAATAAAAAACAAAATCCGCAAGATTTTGCACTATGGAA
AAAAGCCAAAAATGATGAACCATTTTTTGATTCGCCATGGGGTAGAGGTAGGCCAGGATGGCATATTGAATGTTCGGCGA
TGGTTAAAGATGAATTAGGAGATACTATTGATATCCATTTAGGTGGTTCTGATTTAATTTTTCCACATCATGAGAATGAA
ATCGCCCAATCAGAAGCAGCCAATGGCAAAAAGCTAGCGAACTATTGGTTACATAATGGGATGGTCAATGTAAATGGACA
AAAGATGAGTAAATCCCTTAAAAATTTTAAAACTATCAGAGAGCTAATTAAGTCAGGTATAAGCCCTATGACTTTGCGAT
ATTTTGTTATGACTGTGAATTATAGAAAACCACTTGATTTTACTGAAGAAGCTTTAAGGAGTGCTGCAGAAGCTTGGAAA
AACATTAATCTAGCCCTTTCTTTTATGGACCTTACAAAAGGTGCTTTTAGATCTATTGATAAAAATGAATCTATCGAAGA
GGAATATAAAGAGAAATTAAGTTTTGAATTATCTCAAAAAAAGCTTAAATTTTCTGAAGCTCTAGGAAATGACCTTAATA
CAGCAGGTGCTATTGCAATTATTTACGATTTAGCCAAACCATTAAAAAACTTTTTAAACCAATTTCAAAGGATTGAAGGT
TTAAAAATAGACCTAAATGAAAAATTCTTTCTACTTGAGAATTTTAAAACTCTTGAAAAGTTGACTGAGGTACTTGGTCT
TAAAAAAGAGGTTTTAGTAAAAGAAAGGAAAATAACAGAAGAAGAAATATCATCGCTTATTAATGAAAGATTGAAAGCAA
AAAAGGGAAAGAATTATGCGAAGGCTGATGAAATCAGGAATTTGTTAAAAGAAAAAGGTATTGAACTTATTGATCAATCA
AAGGAAATAACAACATGGATAAGGGTCTAA

Upstream 100 bases:

>100_bases
GGAAGATTGTGTAAAATTGAATGTGCCTCTTTTAGTTGATATTGGCATTGGAGACAATTGGATGGAGACAAAATAAACCT
TATGAAATACTTAATTTAAG

Downstream 100 bases:

>100_bases
ATTTTAAGAAAAAACCCAATTTGAAATTTTTGTTTTTTAAATACACCTTTAAGTGGGAAGATATTAGAAATATCAGAGAA
AATTGAAATACATTACTGTT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MIKLFNTLSKRVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKVKYVQNFTDIDDKILKRAKEE
SSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNICSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNIQE
QNINKQGRMANEENNKKQNPQDFALWKKAKNDEPFFDSPWGRGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENE
IAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVNYRKPLDFTEEALRSAAEAWK
NINLALSFMDLTKGAFRSIDKNESIEEEYKEKLSFELSQKKLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRIEG
LKIDLNEKFFLLENFKTLEKLTEVLGLKKEVLVKERKITEEEISSLINERLKAKKGKNYAKADEIRNLLKEKGIELIDQS
KEITTWIRV

Sequences:

>Translated_489_residues
MIKLFNTLSKRVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKVKYVQNFTDIDDKILKRAKEE
SSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNICSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNIQE
QNINKQGRMANEENNKKQNPQDFALWKKAKNDEPFFDSPWGRGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENE
IAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVNYRKPLDFTEEALRSAAEAWK
NINLALSFMDLTKGAFRSIDKNESIEEEYKEKLSFELSQKKLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRIEG
LKIDLNEKFFLLENFKTLEKLTEVLGLKKEVLVKERKITEEEISSLINERLKAKKGKNYAKADEIRNLLKEKGIELIDQS
KEITTWIRV
>Mature_489_residues
MIKLFNTLSKRVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKVKYVQNFTDIDDKILKRAKEE
SSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNICSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNIQE
QNINKQGRMANEENNKKQNPQDFALWKKAKNDEPFFDSPWGRGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENE
IAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVNYRKPLDFTEEALRSAAEAWK
NINLALSFMDLTKGAFRSIDKNESIEEEYKEKLSFELSQKKLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRIEG
LKIDLNEKFFLLENFKTLEKLTEVLGLKKEVLVKERKITEEEISSLINERLKAKKGKNYAKADEIRNLLKEKGIELIDQS
KEITTWIRV

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=392, Percent_Identity=36.9897959183673, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI21269877, Length=292, Percent_Identity=36.986301369863, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI303304987, Length=292, Percent_Identity=36.986301369863, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI10835051, Length=292, Percent_Identity=36.986301369863, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI62240992, Length=292, Percent_Identity=36.986301369863, Blast_Score=192, Evalue=7e-49,
Organism=Escherichia coli, GI1786737, Length=497, Percent_Identity=42.2535211267606, Blast_Score=356, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17509795, Length=308, Percent_Identity=36.3636363636364, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17509797, Length=308, Percent_Identity=36.3636363636364, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324082, Length=229, Percent_Identity=44.5414847161572, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI19922218, Length=517, Percent_Identity=33.2688588007737, Blast_Score=228, Evalue=6e-60,
Organism=Drosophila melanogaster, GI19922364, Length=307, Percent_Identity=37.785016286645, Blast_Score=201, Evalue=8e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56601; Mature: 56601

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLFNTLSKRVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKV
CCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHH
KYVQNFTDIDDKILKRAKEESSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
CSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNIQEQNINKQGRMANEENNKKQNP
HHHHHHHCCCCCEECCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
QDFALWKKAKNDEPFFDSPWGRGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENE
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCEEEEEECCCCEECCCCCCH
IAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVN
HHHHHCCCCHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEEC
YRKPLDFTEEALRSAAEAWKNINLALSFMDLTKGAFRSIDKNESIEEEYKEKLSFELSQK
CCCCCCHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
KLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRIEGLKIDLNEKFFLLENFKTLEK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEHHHHHHHHH
LTEVLGLKKEVLVKERKITEEEISSLINERLKAKKGKNYAKADEIRNLLKEKGIELIDQS
HHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHCC
KEITTWIRV
CHHHHHHCC
>Mature Secondary Structure
MIKLFNTLSKRVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKV
CCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHH
KYVQNFTDIDDKILKRAKEESSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
CSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNIQEQNINKQGRMANEENNKKQNP
HHHHHHHCCCCCEECCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
QDFALWKKAKNDEPFFDSPWGRGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENE
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCEEEEEECCCCEECCCCCCH
IAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVN
HHHHHCCCCHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEEC
YRKPLDFTEEALRSAAEAWKNINLALSFMDLTKGAFRSIDKNESIEEEYKEKLSFELSQK
CCCCCCHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
KLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRIEGLKIDLNEKFFLLENFKTLEK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEHHHHHHHHH
LTEVLGLKKEVLVKERKITEEEISSLINERLKAKKGKNYAKADEIRNLLKEKGIELIDQS
HHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHCC
KEITTWIRV
CHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA