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The map label for this gene is pilQ [H]

Identifier: 78779577

GI number: 78779577

Start: 1114072

End: 1115742

Strand: Direct

Name: pilQ [H]

Synonym: PMT9312_1194

Alternate gene names: 78779577

Gene position: 1114072-1115742 (Clockwise)

Preceding gene: 78779576

Following gene: 78779585

Centisome position: 65.18

GC content: 31.96

Gene sequence:

>1671_bases
ATGGTTATAAGAAAATTAGCAATTTATTCTTTTGCAGGAATAATATTAAGCCTAAATTTAGCCATTAATGCAAATACATC
AAATAAAAACTTTTCTGTTAATAGGAATGTTCTCACAAAAAACAAAAATTTAAATGAAAAAAAAATTAAGCCTCAAGTAA
TATTTCTAGCCGAAAATCAATATCAATCTAATAAGATTGATATTGATGACTCCAAACCTATTGCAAATCCAAATTTAATA
AATATAAAAGGTCCTAAGATATCAATAATATTAAACAAAACACCTGCTAAAAAGGCGTTCGAGTACCTAGCTAAATTGGG
GAATTATGGTTTCGTGTGGATTAAAAATGATCCAACTAATAAAGATGAGAAAGGATCCGGAAAAGCTGATGATCAAAGAC
TAATTACTTTGAATATGAAAAATGTTAATTTTAGACGTGCATTTAACGCCATTATTATTGCTAGTGGATTACAAGCAAAA
ATCTATAACAACGTAATTTATGTAGGACCAAATGTAAGGAATACAGTTTTCACTTATAGAGAAACAGCAATAATCCAATT
AAATCAAATTACAGCTAGTTCTGCCGCAGATTATCTAGCCAATTTAGGAGCAAGAGTTACTAAAACTTTTACAGTAAGTA
CTTCGGTTACTGAAGGTGCCTCTCAGTCACAAAGTATTCAAGGTGGAGCTTCTTCATCAACTACTACATCACAATCAGAC
ACAAAAGTAAAAACTTACGGAGCGGATATTGGTCCTCTCGTTGGGTTAATAGCTACTACAGATGAAAGACTTCAAACCAT
AACTCTTGTTGGAGAAAAAAATATACTTAGATTAGCTAAATCTTATCTTAAAAATTTAGATAAAAGACAAAAACAAGTTG
CTTTAAATGTAAAAGTTTTAGATGTAAACCTTTCGGACAAAGATTCATTTTCTCAATCTTGGTTCCTTCCATTTGGCTCT
GGATCACCATACATAATTACTCAATCTCCAAATTTAAAAGCAGGCATTGGGCCAGATCGTTTAGGTAAATTTGTAAGTAG
TGAGCTAACAGCAAGTATTCAAAAAGGTACTACAAAAGTTCTTGCTAGTCCTACACTAATATTAAATGAATCAGGAGGTT
CTGCTGGTGATGGCTCTTCAATAGGACGAAGACTAGCAAATGAAGGTTTTGTTGAAGTAGGAGATCAAGTACCTGTTAAT
GCAACTTTTGTAGAAGGTTCTGGTTGTAATTTTACATATGATTTAGTAGGAATAAAACTTGGAGCGAAAGTTCTGGGAAT
AGATAGAAATAGATTTGTTACATTTGCAATGACTCCAATAGTTACCGGAATTTCTGGAACTCAGACAATTACAAATTGCG
GAGAAGTTAACCTTTTAAACACCCGAAGATTAGATACTGGTGCCGTGAGAATAAAAAATGGTGAAACCTTAGTACTCACA
GGAGTAATTCAAGATTCAGATATAGAAACATTAGTAAAATTTCCGATATTAGGAGATCTTCCTATTATGGGCCCGCTTTT
CCGTTCCACTTCAAAAGAAGTTGGCAAAAGAGAATTAATAGTTTTAGTAACCCCAAGAATTATTGACGATAAAGGGGATA
ATCTCAAAAACTATGATTTTAAGCTTAACAATAAAGAATCTATTGATTTAATTAATTCCCTTAAAGATTAA

Upstream 100 bases:

>100_bases
GTAAAATTTTTAAGTTTGAATGATTTCTAAAAATTTATTCTTTTTGATAAACAAATAGCTAATTATTAAGACTTAGCTAA
AATAATAAATAAACCCAAGT

Downstream 100 bases:

>100_bases
AATTTTTTTTTCAATAATATATCTATTTAATATAAGTACATTGCGATTCATCTCCCATTGAAATTCTTCCCATCCAGTTA
TCATTCAGATAATTTTTATT

Product: Type II secretory pathway component PulD-like

Products: NA

Alternate protein names: Outer membrane protein omc [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MVIRKLAIYSFAGIILSLNLAINANTSNKNFSVNRNVLTKNKNLNEKKIKPQVIFLAENQYQSNKIDIDDSKPIANPNLI
NIKGPKISIILNKTPAKKAFEYLAKLGNYGFVWIKNDPTNKDEKGSGKADDQRLITLNMKNVNFRRAFNAIIIASGLQAK
IYNNVIYVGPNVRNTVFTYRETAIIQLNQITASSAADYLANLGARVTKTFTVSTSVTEGASQSQSIQGGASSSTTTSQSD
TKVKTYGADIGPLVGLIATTDERLQTITLVGEKNILRLAKSYLKNLDKRQKQVALNVKVLDVNLSDKDSFSQSWFLPFGS
GSPYIITQSPNLKAGIGPDRLGKFVSSELTASIQKGTTKVLASPTLILNESGGSAGDGSSIGRRLANEGFVEVGDQVPVN
ATFVEGSGCNFTYDLVGIKLGAKVLGIDRNRFVTFAMTPIVTGISGTQTITNCGEVNLLNTRRLDTGAVRIKNGETLVLT
GVIQDSDIETLVKFPILGDLPIMGPLFRSTSKEVGKRELIVLVTPRIIDDKGDNLKNYDFKLNNKESIDLINSLKD

Sequences:

>Translated_556_residues
MVIRKLAIYSFAGIILSLNLAINANTSNKNFSVNRNVLTKNKNLNEKKIKPQVIFLAENQYQSNKIDIDDSKPIANPNLI
NIKGPKISIILNKTPAKKAFEYLAKLGNYGFVWIKNDPTNKDEKGSGKADDQRLITLNMKNVNFRRAFNAIIIASGLQAK
IYNNVIYVGPNVRNTVFTYRETAIIQLNQITASSAADYLANLGARVTKTFTVSTSVTEGASQSQSIQGGASSSTTTSQSD
TKVKTYGADIGPLVGLIATTDERLQTITLVGEKNILRLAKSYLKNLDKRQKQVALNVKVLDVNLSDKDSFSQSWFLPFGS
GSPYIITQSPNLKAGIGPDRLGKFVSSELTASIQKGTTKVLASPTLILNESGGSAGDGSSIGRRLANEGFVEVGDQVPVN
ATFVEGSGCNFTYDLVGIKLGAKVLGIDRNRFVTFAMTPIVTGISGTQTITNCGEVNLLNTRRLDTGAVRIKNGETLVLT
GVIQDSDIETLVKFPILGDLPIMGPLFRSTSKEVGKRELIVLVTPRIIDDKGDNLKNYDFKLNNKESIDLINSLKD
>Mature_556_residues
MVIRKLAIYSFAGIILSLNLAINANTSNKNFSVNRNVLTKNKNLNEKKIKPQVIFLAENQYQSNKIDIDDSKPIANPNLI
NIKGPKISIILNKTPAKKAFEYLAKLGNYGFVWIKNDPTNKDEKGSGKADDQRLITLNMKNVNFRRAFNAIIIASGLQAK
IYNNVIYVGPNVRNTVFTYRETAIIQLNQITASSAADYLANLGARVTKTFTVSTSVTEGASQSQSIQGGASSSTTTSQSD
TKVKTYGADIGPLVGLIATTDERLQTITLVGEKNILRLAKSYLKNLDKRQKQVALNVKVLDVNLSDKDSFSQSWFLPFGS
GSPYIITQSPNLKAGIGPDRLGKFVSSELTASIQKGTTKVLASPTLILNESGGSAGDGSSIGRRLANEGFVEVGDQVPVN
ATFVEGSGCNFTYDLVGIKLGAKVLGIDRNRFVTFAMTPIVTGISGTQTITNCGEVNLLNTRRLDTGAVRIKNGETLVLT
GVIQDSDIETLVKFPILGDLPIMGPLFRSTSKEVGKRELIVLVTPRIIDDKGDNLKNYDFKLNNKESIDLINSLKD

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane. Note=Associated to the membrane through its C-terminus [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=286, Percent_Identity=23.4265734265734, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87082242, Length=72, Percent_Identity=48.6111111111111, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 60382; Mature: 60382

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIRKLAIYSFAGIILSLNLAINANTSNKNFSVNRNVLTKNKNLNEKKIKPQVIFLAENQ
CCEEHHHHHHHEEEEEEEEEEEECCCCCCCEEECCCEEECCCCCCHHCCCCEEEEEECCC
YQSNKIDIDDSKPIANPNLINIKGPKISIILNKTPAKKAFEYLAKLGNYGFVWIKNDPTN
CCCCEEECCCCCCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCC
KDEKGSGKADDQRLITLNMKNVNFRRAFNAIIIASGLQAKIYNNVIYVGPNVRNTVFTYR
CCCCCCCCCCCCEEEEEEECCCCHHHHCCEEEEECCCCEEEECCEEEECCCCCCEEEEEE
ETAIIQLNQITASSAADYLANLGARVTKTFTVSTSVTEGASQSQSIQGGASSSTTTSQSD
CEEEEEEEEECHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
TKVKTYGADIGPLVGLIATTDERLQTITLVGEKNILRLAKSYLKNLDKRQKQVALNVKVL
CEEEECCCCHHHHHEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHEEEEEEEEE
DVNLSDKDSFSQSWFLPFGSGSPYIITQSPNLKAGIGPDRLGKFVSSELTASIQKGTTKV
EEECCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEE
LASPTLILNESGGSAGDGSSIGRRLANEGFVEVGDQVPVNATFVEGSGCNFTYDLVGIKL
EECCEEEEECCCCCCCCCHHHHHHHHCCCCEECCCCCCCEEEEEECCCCCEEEEEEEEEE
GAKVLGIDRNRFVTFAMTPIVTGISGTQTITNCGEVNLLNTRRLDTGAVRIKNGETLVLT
CCEEEEECCCCEEEEEECHHHCCCCCCCEECCCCCEEEEECCCCCCCEEEEECCCEEEEE
GVIQDSDIETLVKFPILGDLPIMGPLFRSTSKEVGKRELIVLVTPRIIDDKGDNLKNYDF
EEECCCCHHHHEECCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCEEECCCCCCCCCCEE
KLNNKESIDLINSLKD
EECCCCHHHHHHHCCC
>Mature Secondary Structure
MVIRKLAIYSFAGIILSLNLAINANTSNKNFSVNRNVLTKNKNLNEKKIKPQVIFLAENQ
CCEEHHHHHHHEEEEEEEEEEEECCCCCCCEEECCCEEECCCCCCHHCCCCEEEEEECCC
YQSNKIDIDDSKPIANPNLINIKGPKISIILNKTPAKKAFEYLAKLGNYGFVWIKNDPTN
CCCCEEECCCCCCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCC
KDEKGSGKADDQRLITLNMKNVNFRRAFNAIIIASGLQAKIYNNVIYVGPNVRNTVFTYR
CCCCCCCCCCCCEEEEEEECCCCHHHHCCEEEEECCCCEEEECCEEEECCCCCCEEEEEE
ETAIIQLNQITASSAADYLANLGARVTKTFTVSTSVTEGASQSQSIQGGASSSTTTSQSD
CEEEEEEEEECHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
TKVKTYGADIGPLVGLIATTDERLQTITLVGEKNILRLAKSYLKNLDKRQKQVALNVKVL
CEEEECCCCHHHHHEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHEEEEEEEEE
DVNLSDKDSFSQSWFLPFGSGSPYIITQSPNLKAGIGPDRLGKFVSSELTASIQKGTTKV
EEECCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEE
LASPTLILNESGGSAGDGSSIGRRLANEGFVEVGDQVPVNATFVEGSGCNFTYDLVGIKL
EECCEEEEECCCCCCCCCHHHHHHHHCCCCEECCCCCCCEEEEEECCCCCEEEEEEEEEE
GAKVLGIDRNRFVTFAMTPIVTGISGTQTITNCGEVNLLNTRRLDTGAVRIKNGETLVLT
CCEEEEECCCCEEEEEECHHHCCCCCCCEECCCCCEEEEECCCCCCCEEEEECCCEEEEE
GVIQDSDIETLVKFPILGDLPIMGPLFRSTSKEVGKRELIVLVTPRIIDDKGDNLKNYDF
EEECCCCHHHHEECCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCEEECCCCCCCCCCEE
KLNNKESIDLINSLKD
EECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA