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The map label for this gene is hisZ

Identifier: 78779284

GI number: 78779284

Start: 830799

End: 831950

Strand: Reverse

Name: hisZ

Synonym: PMT9312_0900

Alternate gene names: 78779284

Gene position: 831950-830799 (Counterclockwise)

Preceding gene: 78779285

Following gene: 78779283

Centisome position: 48.67

GC content: 24.22

Gene sequence:

>1152_bases
ATGACTGATATAAAAGAAATTAAATTAGTAGATGTAAGGAATAACTCCAATATTATAAATAATTTAAATAATATTTATAA
ACTATGGGGTTATGAAGAAGTCTCACCTTCTTTTATAAACACTTTAGAGACGATAAAGGGTCGAGGTGTTATCGAAGAAA
ATGAAATTGTTGGAATAGTAAGTAATAATTCATTATGTCTTAGACCAGAAATGACAACATCTATTGTCAAATTGTCATCT
ACTAGATTAATAAATAAGAAAAGACCTATAAGATTATTTACTAATGGAATAGTCTTTGATAAAAAACAAAATAATAAAAA
TTTATTTAAGTTGCAAGAAAAACTGCATAGTGGAATTGAATTAATTGGATATGATACAAAATACCCAGAAATTGAAGTTA
TTAATATATTGTTTGATGCAATAGATAATATTAATTTGAAGGATGATTGTAATTTAAGTCTATTAGTTAGTACCACAAAA
ATTATGGACTTGATATTGAATAAATATAAAAATAATAATTTTGAAGAAATTAAGAAAAGTCTAGTTAACCTTGATCAAGA
TAAATTATCTAAATTAGGAATTGAGGAAGATGATAAATATATTCTTAAAGATTTATTATTCACAAGAGGTGAACCAATTG
CAATATTAAAAAAATTGAAAAGTATATATGGCAGTAGTAAAACATTAGATGACCTAAATTTTTTATTTGAAATATTATCA
AAAATATCAAATAAATATGGTGTTAAATTACAACTTGATCCTACTTTTCAACCTCACTTGAATTTATACGAAGGAATAGT
TTTTCAACTTATAGGGGATAGTGGTAATAATAAAAACGTGATCGCAAAAGGTGGAAGATATGATGAACTTGTAAGATTCT
TTAGTCCTAATGAGAAAATCCTAAATGGAATTGGATTTACTATTTCAATAGATATTTTAAGAAATTTAATTAAGGAAGAA
AAGACAGATAAGAAAAAAATTTTATTAATGTTTAAAGATTCTAATTTGCTAGAAAAAGGTATGAATAAGCAAAAAGAACT
ACAGAAAAGAGGAAATATTGCTGTCTTACATTTAAATCCATGTGATGACTTTGCTAAAGCCACTTTAATAATGAAAGAAA
ATAATTGTAGTGAGATTTTATGGGTTAAATAA

Upstream 100 bases:

>100_bases
GCTCACCCCGCCTTGAGGATGAATTAAAAAATGAACTAGATAATGTTTCTCCATTTAATAAAAATCTTTATACCTAAAAT
ATAAATCTTTAAATATTAAA

Downstream 100 bases:

>100_bases
AACCTTTTAAGAGTTTATTTAAGTTTTTAAATTCATATTTTGTTCGGACAATACTCCTAATTAAACTTGATTAACTAGTT
TTTAGGAAATAGGATTTAAA

Product: ATP phosphoribosyltransferase regulatory subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTDIKEIKLVDVRNNSNIINNLNNIYKLWGYEEVSPSFINTLETIKGRGVIEENEIVGIVSNNSLCLRPEMTTSIVKLSS
TRLINKKRPIRLFTNGIVFDKKQNNKNLFKLQEKLHSGIELIGYDTKYPEIEVINILFDAIDNINLKDDCNLSLLVSTTK
IMDLILNKYKNNNFEEIKKSLVNLDQDKLSKLGIEEDDKYILKDLLFTRGEPIAILKKLKSIYGSSKTLDDLNFLFEILS
KISNKYGVKLQLDPTFQPHLNLYEGIVFQLIGDSGNNKNVIAKGGRYDELVRFFSPNEKILNGIGFTISIDILRNLIKEE
KTDKKKILLMFKDSNLLEKGMNKQKELQKRGNIAVLHLNPCDDFAKATLIMKENNCSEILWVK

Sequences:

>Translated_383_residues
MTDIKEIKLVDVRNNSNIINNLNNIYKLWGYEEVSPSFINTLETIKGRGVIEENEIVGIVSNNSLCLRPEMTTSIVKLSS
TRLINKKRPIRLFTNGIVFDKKQNNKNLFKLQEKLHSGIELIGYDTKYPEIEVINILFDAIDNINLKDDCNLSLLVSTTK
IMDLILNKYKNNNFEEIKKSLVNLDQDKLSKLGIEEDDKYILKDLLFTRGEPIAILKKLKSIYGSSKTLDDLNFLFEILS
KISNKYGVKLQLDPTFQPHLNLYEGIVFQLIGDSGNNKNVIAKGGRYDELVRFFSPNEKILNGIGFTISIDILRNLIKEE
KTDKKKILLMFKDSNLLEKGMNKQKELQKRGNIAVLHLNPCDDFAKATLIMKENNCSEILWVK
>Mature_382_residues
TDIKEIKLVDVRNNSNIINNLNNIYKLWGYEEVSPSFINTLETIKGRGVIEENEIVGIVSNNSLCLRPEMTTSIVKLSST
RLINKKRPIRLFTNGIVFDKKQNNKNLFKLQEKLHSGIELIGYDTKYPEIEVINILFDAIDNINLKDDCNLSLLVSTTKI
MDLILNKYKNNNFEEIKKSLVNLDQDKLSKLGIEEDDKYILKDLLFTRGEPIAILKKLKSIYGSSKTLDDLNFLFEILSK
ISNKYGVKLQLDPTFQPHLNLYEGIVFQLIGDSGNNKNVIAKGGRYDELVRFFSPNEKILNGIGFTISIDILRNLIKEEK
TDKKKILLMFKDSNLLEKGMNKQKELQKRGNIAVLHLNPCDDFAKATLIMKENNCSEILWVK

Specific function: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine [H]

COG id: COG3705

COG function: function code E; ATP phosphoribosyltransferase involved in histidine biosynthesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004516 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 43938; Mature: 43807

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIKEIKLVDVRNNSNIINNLNNIYKLWGYEEVSPSFINTLETIKGRGVIEENEIVGIV
CCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEECCCEEEEE
SNNSLCLRPEMTTSIVKLSSTRLINKKRPIRLFTNGIVFDKKQNNKNLFKLQEKLHSGIE
ECCCEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCHHHHHHHHHHCCCE
LIGYDTKYPEIEVINILFDAIDNINLKDDCNLSLLVSTTKIMDLILNKYKNNNFEEIKKS
EEECCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHH
LVNLDQDKLSKLGIEEDDKYILKDLLFTRGEPIAILKKLKSIYGSSKTLDDLNFLFEILS
HHCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KISNKYGVKLQLDPTFQPHLNLYEGIVFQLIGDSGNNKNVIAKGGRYDELVRFFSPNEKI
HHCCCCCEEEEECCCCCCCCHHHHCEEEEEECCCCCCCCEEECCCCHHHHHHHHCCCHHH
LNGIGFTISIDILRNLIKEEKTDKKKILLMFKDSNLLEKGMNKQKELQKRGNIAVLHLNP
HHCCCCEEEHHHHHHHHHHCCCCCEEEEEEEECCHHHHHCCCHHHHHHHHCCEEEEEECC
CDDFAKATLIMKENNCSEILWVK
CCCHHHEEEEEECCCCCCEEEEC
>Mature Secondary Structure 
TDIKEIKLVDVRNNSNIINNLNNIYKLWGYEEVSPSFINTLETIKGRGVIEENEIVGIV
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEECCCEEEEE
SNNSLCLRPEMTTSIVKLSSTRLINKKRPIRLFTNGIVFDKKQNNKNLFKLQEKLHSGIE
ECCCEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCHHHHHHHHHHCCCE
LIGYDTKYPEIEVINILFDAIDNINLKDDCNLSLLVSTTKIMDLILNKYKNNNFEEIKKS
EEECCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHH
LVNLDQDKLSKLGIEEDDKYILKDLLFTRGEPIAILKKLKSIYGSSKTLDDLNFLFEILS
HHCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KISNKYGVKLQLDPTFQPHLNLYEGIVFQLIGDSGNNKNVIAKGGRYDELVRFFSPNEKI
HHCCCCCEEEEECCCCCCCCHHHHCEEEEEECCCCCCCCEEECCCCHHHHHHHHCCCHHH
LNGIGFTISIDILRNLIKEEKTDKKKILLMFKDSNLLEKGMNKQKELQKRGNIAVLHLNP
HHCCCCEEEHHHHHHHHHHCCCCCEEEEEEEECCHHHHHCCCHHHHHHHHCCEEEEEECC
CDDFAKATLIMKENNCSEILWVK
CCCHHHEEEEEECCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]