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The map label for this gene is htpG [H]

Identifier: 78779283

GI number: 78779283

Start: 828775

End: 830679

Strand: Reverse

Name: htpG [H]

Synonym: PMT9312_0899

Alternate gene names: 78779283

Gene position: 830679-828775 (Counterclockwise)

Preceding gene: 78779284

Following gene: 78779282

Centisome position: 48.6

GC content: 30.71

Gene sequence:

>1905_bases
ATGGAAAAAGGCGAAATTCGTATTAATACTGAAAATATTTTCCCAATTATTAAGAAGGCAGTATATTCTGACCATGAAAT
CTTTTTAAGAGAACTTGTTAGTAATGGTGTTGACGCAATAAGTAAACGAAGAATGGCCTCTATGGCAGGCGACTGCGAAA
ATACTGAAGAAGCTCAAGTAAAAATATCTATTGACCGTGAAAATAATACCCTAACAATTTCTGATAATGGAATTGGAATG
AATGATGAAGAAATTAAGAAGTACATAAACCAAGTAGCATTCTCGAGCGCAGAAGAATTCCTAACAAAATACAAAAAAAA
TAATGATGAATTTATTGGTCATTTTGGACTTGGTTTTTATTCAAGTTTCATGGTGGCAAATAGAGTTGATATATTAACTA
AATCAGCAATTGGAGAATCAAAAGCTTTCAAATGGTCTTGTGATGGATCACCAAATTTCACGTTAGAGGAGTCGGAAAGA
GAAACAATTGGTACAGATGTGATACTTCACCTACTTGAAGAAGAAAAAGAGTTTATTGAGCCTGAAAGGATTAAATCATT
AATAAAAAAATATTGTGATTTTATGCAAATAGATGTCTTATTGGAAGGTGAGGCAATTAATAAGAAAAATCCTCCTTGGA
GAAAACAACCTAGTGAATTAAAAGATCAAGATTATATTGAGTTATATAAATACCTTTATCCTTTTCAGGGAGATCCACTG
TTATGGATTCATCTAAATACAGATTATCCATATGACATTCAAGGGATATTGTATTTTCCTAAGTTGTCTGGAAGAGCTGA
TTGGGAAAAGGGAGAAATTAAACTATTTTGTAATCAAGTATTCGTAAGCGATTCAATAAAAGAGATAGTACCAAAATACC
TTTTGCCTCTAAGAGGAGTAATTGACTCTACAGATATCCCCCTAAATGTCAGTAGAAGCGCATTACAAACAGATAGAAAA
GTAAGATCTATATCATCATTTATTTCAAAAAAAATCGCTAATAAACTGAAGGATTTGATAAAAAAATCACCAGAATTTTA
TGCAGAAATTTGGGATTCCATTTCTGCTTTTATTAAAATTGGCGCTATCGAAGATGAAAAATTTGCTGATTTAGTAGATA
ACAGCATAATTTTCGAAACAATCATAAATCCAGAGAAAGACTTAAAAAAAGATATCGAAAATAAATCACTTATCAAATCA
AATGATAAATATTTTACAACTCTCGCAAATTATAAAGAACGTAATAAGATAACTGATTCTAAAAAAATAATTTACTGTTC
AGATTTGATTGCTCAGTCAAGCGCATTAAATATCTGTTTATCTGATAGCAAAGAAGTTATTAAATCAGATCCCTTAATTG
ATGCACAATTCCTTCCTTGGTTAGAAAGTAAAAACGAAGATTATCAATTCCAAAGAGTTGATTCAGAAATCAATGAACTA
GAAGATACGGAATCTAAAGAAATTGTAGATAAGGATGGCAAATCAAATACAGAAAATCTTAGAGATACAATTGTAAAAGC
ACTTAACAATGAGAAAGTAACAGTTAAAGTGCAATCACTTCCAAGTAAAGGTGCTCCACCTGCAATGATCTTGCTTCCAG
AACAAATGAGAAGAATTAACGATATGGGTGCTTACATGGAACAAAAGATGCCTGGCTTACCTGAATATCATGTGCTCTTA
ATTAACAAAGAACATCCACTTATTGTTGGCCTTAATAAAATTACAGGCAATAAAATAATTATTGATGAAAAAGATACTAT
TGAAAATCCATTGGCATCTAAAATTGCTAATCAAGTTTACGATATGGCTAAACTTTCCGTTGGTGGATTAGATCAAGAAC
AGATTATTAATTTACAAAATAATAATGCCGAATTAATTTCAGAATTGCTTAATTCAACGATTTAA

Upstream 100 bases:

>100_bases
TAAGTTTTTAAATTCATATTTTGTTCGGACAATACTCCTAATTAAACTTGATTAACTAGTTTTTAGGAAATAGGATTTAA
AATGTTAGATTTTTTTTTAA

Downstream 100 bases:

>100_bases
GTCGTATGTTAAAATTTTTAAAGATCTAACTCAAAAAATATGTCAAGGGTTTGCGAACTAACTGGGGCAAAAGCCAATAA
CGGAATGGCCGTCAGCCACT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNGVDAISKRRMASMAGDCENTEEAQVKISIDRENNTLTISDNGIGM
NDEEIKKYINQVAFSSAEEFLTKYKKNNDEFIGHFGLGFYSSFMVANRVDILTKSAIGESKAFKWSCDGSPNFTLEESER
ETIGTDVILHLLEEEKEFIEPERIKSLIKKYCDFMQIDVLLEGEAINKKNPPWRKQPSELKDQDYIELYKYLYPFQGDPL
LWIHLNTDYPYDIQGILYFPKLSGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGVIDSTDIPLNVSRSALQTDRK
VRSISSFISKKIANKLKDLIKKSPEFYAEIWDSISAFIKIGAIEDEKFADLVDNSIIFETIINPEKDLKKDIENKSLIKS
NDKYFTTLANYKERNKITDSKKIIYCSDLIAQSSALNICLSDSKEVIKSDPLIDAQFLPWLESKNEDYQFQRVDSEINEL
EDTESKEIVDKDGKSNTENLRDTIVKALNNEKVTVKVQSLPSKGAPPAMILLPEQMRRINDMGAYMEQKMPGLPEYHVLL
INKEHPLIVGLNKITGNKIIIDEKDTIENPLASKIANQVYDMAKLSVGGLDQEQIINLQNNNAELISELLNSTI

Sequences:

>Translated_634_residues
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNGVDAISKRRMASMAGDCENTEEAQVKISIDRENNTLTISDNGIGM
NDEEIKKYINQVAFSSAEEFLTKYKKNNDEFIGHFGLGFYSSFMVANRVDILTKSAIGESKAFKWSCDGSPNFTLEESER
ETIGTDVILHLLEEEKEFIEPERIKSLIKKYCDFMQIDVLLEGEAINKKNPPWRKQPSELKDQDYIELYKYLYPFQGDPL
LWIHLNTDYPYDIQGILYFPKLSGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGVIDSTDIPLNVSRSALQTDRK
VRSISSFISKKIANKLKDLIKKSPEFYAEIWDSISAFIKIGAIEDEKFADLVDNSIIFETIINPEKDLKKDIENKSLIKS
NDKYFTTLANYKERNKITDSKKIIYCSDLIAQSSALNICLSDSKEVIKSDPLIDAQFLPWLESKNEDYQFQRVDSEINEL
EDTESKEIVDKDGKSNTENLRDTIVKALNNEKVTVKVQSLPSKGAPPAMILLPEQMRRINDMGAYMEQKMPGLPEYHVLL
INKEHPLIVGLNKITGNKIIIDEKDTIENPLASKIANQVYDMAKLSVGGLDQEQIINLQNNNAELISELLNSTI
>Mature_634_residues
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNGVDAISKRRMASMAGDCENTEEAQVKISIDRENNTLTISDNGIGM
NDEEIKKYINQVAFSSAEEFLTKYKKNNDEFIGHFGLGFYSSFMVANRVDILTKSAIGESKAFKWSCDGSPNFTLEESER
ETIGTDVILHLLEEEKEFIEPERIKSLIKKYCDFMQIDVLLEGEAINKKNPPWRKQPSELKDQDYIELYKYLYPFQGDPL
LWIHLNTDYPYDIQGILYFPKLSGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGVIDSTDIPLNVSRSALQTDRK
VRSISSFISKKIANKLKDLIKKSPEFYAEIWDSISAFIKIGAIEDEKFADLVDNSIIFETIINPEKDLKKDIENKSLIKS
NDKYFTTLANYKERNKITDSKKIIYCSDLIAQSSALNICLSDSKEVIKSDPLIDAQFLPWLESKNEDYQFQRVDSEINEL
EDTESKEIVDKDGKSNTENLRDTIVKALNNEKVTVKVQSLPSKGAPPAMILLPEQMRRINDMGAYMEQKMPGLPEYHVLL
INKEHPLIVGLNKITGNKIIIDEKDTIENPLASKIANQVYDMAKLSVGGLDQEQIINLQNNNAELISELLNSTI

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=636, Percent_Identity=27.2012578616352, Blast_Score=239, Evalue=7e-63,
Organism=Homo sapiens, GI4507677, Length=657, Percent_Identity=27.7016742770167, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI153792590, Length=193, Percent_Identity=34.7150259067358, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI154146191, Length=192, Percent_Identity=34.8958333333333, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI20149594, Length=195, Percent_Identity=35.3846153846154, Blast_Score=115, Evalue=2e-25,
Organism=Escherichia coli, GI1786679, Length=376, Percent_Identity=34.0425531914894, Blast_Score=228, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI115535205, Length=648, Percent_Identity=28.2407407407407, Blast_Score=237, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI115535167, Length=436, Percent_Identity=31.1926605504587, Blast_Score=228, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17542208, Length=690, Percent_Identity=28.2608695652174, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17559162, Length=413, Percent_Identity=26.634382566586, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6325016, Length=204, Percent_Identity=34.8039215686275, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323840, Length=217, Percent_Identity=32.7188940092166, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24586016, Length=667, Percent_Identity=28.9355322338831, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI21357739, Length=689, Percent_Identity=27.1407837445573, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI17647529, Length=197, Percent_Identity=31.9796954314721, Blast_Score=106, Evalue=6e-23,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72418; Mature: 72418

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNGVDAISKRRMASMAGDCENTEEAQV
CCCCCEEEECHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEE
KISIDRENNTLTISDNGIGMNDEEIKKYINQVAFSSAEEFLTKYKKNNDEFIGHFGLGFY
EEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHH
SSFMVANRVDILTKSAIGESKAFKWSCDGSPNFTLEESERETIGTDVILHLLEEEKEFIE
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCC
PERIKSLIKKYCDFMQIDVLLEGEAINKKNPPWRKQPSELKDQDYIELYKYLYPFQGDPL
HHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCE
LWIHLNTDYPYDIQGILYFPKLSGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGV
EEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHC
IDSTDIPLNVSRSALQTDRKVRSISSFISKKIANKLKDLIKKSPEFYAEIWDSISAFIKI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEE
GAIEDEKFADLVDNSIIFETIINPEKDLKKDIENKSLIKSNDKYFTTLANYKERNKITDS
CCCCCHHHHHHHCCCEEEEHHCCCHHHHHHHCCCCHHHCCCCCEEEHHHHHHHHCCCCCC
KKIIYCSDLIAQSSALNICLSDSKEVIKSDPLIDAQFLPWLESKNEDYQFQRVDSEINEL
CEEEEEHHHHHCCCCCEEEECCCHHHHHCCCCCCHHHCCHHCCCCCCCHHHHHHHHHHHH
EDTESKEIVDKDGKSNTENLRDTIVKALNNEKVTVKVQSLPSKGAPPAMILLPEQMRRIN
HCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEECHHHHHHHH
DMGAYMEQKMPGLPEYHVLLINKEHPLIVGLNKITGNKIIIDEKDTIENPLASKIANQVY
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEECCHHHCCHHHHHHHHHHH
DMAKLSVGGLDQEQIINLQNNNAELISELLNSTI
HHHHHCCCCCCHHHHEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNGVDAISKRRMASMAGDCENTEEAQV
CCCCCEEEECHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEE
KISIDRENNTLTISDNGIGMNDEEIKKYINQVAFSSAEEFLTKYKKNNDEFIGHFGLGFY
EEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHH
SSFMVANRVDILTKSAIGESKAFKWSCDGSPNFTLEESERETIGTDVILHLLEEEKEFIE
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCC
PERIKSLIKKYCDFMQIDVLLEGEAINKKNPPWRKQPSELKDQDYIELYKYLYPFQGDPL
HHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCE
LWIHLNTDYPYDIQGILYFPKLSGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGV
EEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHC
IDSTDIPLNVSRSALQTDRKVRSISSFISKKIANKLKDLIKKSPEFYAEIWDSISAFIKI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEE
GAIEDEKFADLVDNSIIFETIINPEKDLKKDIENKSLIKSNDKYFTTLANYKERNKITDS
CCCCCHHHHHHHCCCEEEEHHCCCHHHHHHHCCCCHHHCCCCCEEEHHHHHHHHCCCCCC
KKIIYCSDLIAQSSALNICLSDSKEVIKSDPLIDAQFLPWLESKNEDYQFQRVDSEINEL
CEEEEEHHHHHCCCCCEEEECCCHHHHHCCCCCCHHHCCHHCCCCCCCHHHHHHHHHHHH
EDTESKEIVDKDGKSNTENLRDTIVKALNNEKVTVKVQSLPSKGAPPAMILLPEQMRRIN
HCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEECHHHHHHHH
DMGAYMEQKMPGLPEYHVLLINKEHPLIVGLNKITGNKIIIDEKDTIENPLASKIANQVY
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEECCHHHCCHHHHHHHHHHH
DMAKLSVGGLDQEQIINLQNNNAELISELLNSTI
HHHHHCCCCCCHHHHEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10722592 [H]