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The map label for this gene is map [C]

Identifier: 78778862

GI number: 78778862

Start: 447308

End: 448147

Strand: Direct

Name: map [C]

Synonym: PMT9312_0477

Alternate gene names: 78778862

Gene position: 447308-448147 (Clockwise)

Preceding gene: 78778857

Following gene: 78778864

Centisome position: 26.17

GC content: 33.45

Gene sequence:

>840_bases
ATGAAACATTTTGCAGATCTTTTATTAAATAAAAATAATTCCAAAACCAATAATCAAGTTCCTTTTATACAGAGGAGAAG
AGGAATTGAAATAAAGTCTGCACGTGAAATAAATTTGATGAAAAAATCTAGCAGGATAGTCGCAACAGTTTTGAGGGAAA
TTAATGACTTAATTAAACCTGGAATGAGCACTAAAGATTTAGATGATTTTGCAGAGAAGAGGATAAAAAGTTTTGGTGCT
GTGCCAAGTTTTAAGGGCTATCATGGTTTCCCTTCTAGTATTTGTTCTAGTATCAATAATGAGGTTGTCCATGGGATACC
AAATAAAAATAAAATAATTAAAAATGGTGACTTAGTTAAAATTGATACAGGAGCATATTTAGATGGCTTCCATGGGGATA
GTTGCATATCAATTTGTGTAGGAGAAGTAAGTTCAAAGGTCCAAAATCTTAGTGATGTAGCTTATAAAGCATTGTATGCT
GGCCTTTCAAAAATTAAGGCAGGGAATACACTTCTCGATGTGGCTGGGGAAATCGAAGATGTTGTTGTAAAAAATGGCTT
TAGTGTTGTTGAAGATTACACAGGCCATGGAGTTGGCAGAAATCTTCATGAAGAACCATCGGTATTTAATTTTCGGACTA
AAGAATTGCCCAACGTCATACTTCGTGAAGGAATGACATTAGCTGTGGAACCTATTGTTAATGAAGGGACTAAATTTTGT
AAAACATTAAATGATAAATGGACAGTCATAACAAAAGATGGAAAATTATCTGCGCAATGGGAGCATACAATAGTTGTTTT
AAAAGATGGAATTGAAATATTGACAGATAGAGATTTCTAG

Upstream 100 bases:

>100_bases
AAATTTCATTCCTGTTTCCCATTGTTATTGATAGATTTAAGATAGCCAAGACCGTAATGGCTATTTTGATGATATTTACC
TATTACTATTATTTATTCCA

Downstream 100 bases:

>100_bases
GCACTATGATTTGTATTTATAGATAATTTGGCAATACAAAAAATTAAAAAATTCTTTTAGTGGGAACAGTATGTAGGTTA
AAGGGTTTGGACTAATTATT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKHFADLLLNKNNSKTNNQVPFIQRRRGIEIKSAREINLMKKSSRIVATVLREINDLIKPGMSTKDLDDFAEKRIKSFGA
VPSFKGYHGFPSSICSSINNEVVHGIPNKNKIIKNGDLVKIDTGAYLDGFHGDSCISICVGEVSSKVQNLSDVAYKALYA
GLSKIKAGNTLLDVAGEIEDVVVKNGFSVVEDYTGHGVGRNLHEEPSVFNFRTKELPNVILREGMTLAVEPIVNEGTKFC
KTLNDKWTVITKDGKLSAQWEHTIVVLKDGIEILTDRDF

Sequences:

>Translated_279_residues
MKHFADLLLNKNNSKTNNQVPFIQRRRGIEIKSAREINLMKKSSRIVATVLREINDLIKPGMSTKDLDDFAEKRIKSFGA
VPSFKGYHGFPSSICSSINNEVVHGIPNKNKIIKNGDLVKIDTGAYLDGFHGDSCISICVGEVSSKVQNLSDVAYKALYA
GLSKIKAGNTLLDVAGEIEDVVVKNGFSVVEDYTGHGVGRNLHEEPSVFNFRTKELPNVILREGMTLAVEPIVNEGTKFC
KTLNDKWTVITKDGKLSAQWEHTIVVLKDGIEILTDRDF
>Mature_279_residues
MKHFADLLLNKNNSKTNNQVPFIQRRRGIEIKSAREINLMKKSSRIVATVLREINDLIKPGMSTKDLDDFAEKRIKSFGA
VPSFKGYHGFPSSICSSINNEVVHGIPNKNKIIKNGDLVKIDTGAYLDGFHGDSCISICVGEVSSKVQNLSDVAYKALYA
GLSKIKAGNTLLDVAGEIEDVVVKNGFSVVEDYTGHGVGRNLHEEPSVFNFRTKELPNVILREGMTLAVEPIVNEGTKFC
KTLNDKWTVITKDGKLSAQWEHTIVVLKDGIEILTDRDF

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=33.8709677419355, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI164420681, Length=249, Percent_Identity=34.136546184739, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI1786364, Length=251, Percent_Identity=44.6215139442231, Blast_Score=216, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71996291, Length=253, Percent_Identity=33.596837944664, Blast_Score=154, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6323273, Length=255, Percent_Identity=35.6862745098039, Blast_Score=172, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=36.1788617886179, Blast_Score=161, Evalue=4e-40,
Organism=Drosophila melanogaster, GI21355531, Length=253, Percent_Identity=34.7826086956522, Blast_Score=155, Evalue=2e-38,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30907; Mature: 30907

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFADLLLNKNNSKTNNQVPFIQRRRGIEIKSAREINLMKKSSRIVATVLREINDLIKP
CCHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GMSTKDLDDFAEKRIKSFGAVPSFKGYHGFPSSICSSINNEVVHGIPNKNKIIKNGDLVK
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCEEECCCEEE
IDTGAYLDGFHGDSCISICVGEVSSKVQNLSDVAYKALYAGLSKIKAGNTLLDVAGEIED
EECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VVVKNGFSVVEDYTGHGVGRNLHEEPSVFNFRTKELPNVILREGMTLAVEPIVNEGTKFC
HHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHH
KTLNDKWTVITKDGKLSAQWEHTIVVLKDGIEILTDRDF
HHCCCCEEEEEECCCEEEEECEEEEEEECCCEEECCCCC
>Mature Secondary Structure
MKHFADLLLNKNNSKTNNQVPFIQRRRGIEIKSAREINLMKKSSRIVATVLREINDLIKP
CCHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GMSTKDLDDFAEKRIKSFGAVPSFKGYHGFPSSICSSINNEVVHGIPNKNKIIKNGDLVK
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCEEECCCEEE
IDTGAYLDGFHGDSCISICVGEVSSKVQNLSDVAYKALYAGLSKIKAGNTLLDVAGEIED
EECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VVVKNGFSVVEDYTGHGVGRNLHEEPSVFNFRTKELPNVILREGMTLAVEPIVNEGTKFC
HHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHH
KTLNDKWTVITKDGKLSAQWEHTIVVLKDGIEILTDRDF
HHCCCCEEEEEECCCEEEEECEEEEEEECCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]