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The map label for this gene is engA

Identifier: 78778772

GI number: 78778772

Start: 368156

End: 369529

Strand: Direct

Name: engA

Synonym: PMT9312_0387

Alternate gene names: 78778772

Gene position: 368156-369529 (Clockwise)

Preceding gene: 78778771

Following gene: 78778773

Centisome position: 21.54

GC content: 34.06

Gene sequence:

>1374_bases
TTGATTCTCCCTACAATAGCAATTATCGGAAGACCTAATGTTGGTAAATCTACCTTGGTGAATCGTCTTTGCCAAAGTAA
TGATGCAATAGTATTTGATAAACCAGGTGTTACAAGAGATAGAACTTATCAAAATGCGTCATGGGGAGGTAAGGAATTTC
AAATAGTTGATACTGGAGGTTTAGTTTTTGATGATGATAGTGAATTTCTTCCAGAGATAAGAGCACAAGTTTTCTTGGCT
CTAGAAGAGGCTTCACTCGCTTTACTTGTGGTAGATGGAAACCAAGGTGTTACTGATGGTGATTTATCAATTGCAAAATG
GTTAAGAAACTCAAGTTGTAAAACAATTATTGCTGTTAATAAATGTGAATCCACTACTCTTGGAATTTCTTTAGCTTCAG
AATTCTGGAAATTAGGATTGGGCGAACCTTACCCTGTTTCCGCTATTCATGGCTCAGGAACTGGCGATCTTTTAGATCTC
GTTATTGGCGAACTTCCTGAAAATAATATTCAGGAAGAAGAAGAAAAGATAATGATGTCAATTATTGGCAGGCCAAATGT
TGGTAAATCTAGTTTGTTAAATTCAATTTCTGGAGAAAAAAGAGCAATAGTTAGTGATATTAGTGGAACTACAACTGATT
CAATAGATACGCTTATTAAAAAAGGTGATACTCAATGGAAAATTGTTGATACTGCAGGAATTAGAAGAAAGAAAAATGTT
AAATACGGTACTGAATTCTTTGGTATTAATAGGGCTTTTAAATCTATTGATAGAAGTGATGTTTGTGTGTTAGTCATAGA
TGCTATAGATGGAGTAACTGATCAAGACCAGAAGTTGGCAGGACGAATAGAAGAACAAGGCAGAGCTTGCATAATTGTTA
TAAATAAATGGGACCTTGTTGAAAAAAATAGTTCAACAATTTATCAAGTAGAAAAAGAACTTAGATCTAAACTTTATTTT
TTACACTGGTCAAAAATGATTTTTATATCTGCCCTAACTGGTCAAAGAGTCGATAATATTTTTGAGCATGCTCTTAAGGC
TGTAAATCAACATAGAAGAAGAGTTGCAACATCTGTAGTTAATGAAGTGCTCAAAGAATCTATTAGTTGGAAAAGTCCTC
CAACGAAAAGAAGCGGCAAGCAAGGAAGGCTCTATTACGGTACTCAAGTGAAGAATAAGCCTCCCACTTTTACTCTTTTT
GTAAACGATCCTAAATTATTTGGAATAACTTACAGAAGATATATTGAAAAACAAATTAGATTAAATTTAGGCTTTGAAGG
CACACCTCTCATCTTACTTTGGCGAGGAAAACAACAAAGAGCATTAAATAAAGAAGTCGAGAGGGGAAATATTGAGTTAG
TTCAAAAAGATTAA

Upstream 100 bases:

>100_bases
ATTTTGGCGATCCAGAAATCAAATAAATCTTTTTTAATAAGGTAAACGATTCTATTAAAGGTATAGTTGTAATGGATACT
AATTTCTTTGGAGAGAAGAA

Downstream 100 bases:

>100_bases
TGAATTTACTAACCAAATTTTCTGTTGGTCAATATGTTTATGGCAATAGAAGTTGGCTAAGAATTATAGATAGTAGATTA
AAAATAATTATAGTAATGAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MILPTIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQIVDTGGLVFDDDSEFLPEIRAQVFLA
LEEASLALLVVDGNQGVTDGDLSIAKWLRNSSCKTIIAVNKCESTTLGISLASEFWKLGLGEPYPVSAIHGSGTGDLLDL
VIGELPENNIQEEEEKIMMSIIGRPNVGKSSLLNSISGEKRAIVSDISGTTTDSIDTLIKKGDTQWKIVDTAGIRRKKNV
KYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACIIVINKWDLVEKNSSTIYQVEKELRSKLYF
LHWSKMIFISALTGQRVDNIFEHALKAVNQHRRRVATSVVNEVLKESISWKSPPTKRSGKQGRLYYGTQVKNKPPTFTLF
VNDPKLFGITYRRYIEKQIRLNLGFEGTPLILLWRGKQQRALNKEVERGNIELVQKD

Sequences:

>Translated_457_residues
MILPTIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQIVDTGGLVFDDDSEFLPEIRAQVFLA
LEEASLALLVVDGNQGVTDGDLSIAKWLRNSSCKTIIAVNKCESTTLGISLASEFWKLGLGEPYPVSAIHGSGTGDLLDL
VIGELPENNIQEEEEKIMMSIIGRPNVGKSSLLNSISGEKRAIVSDISGTTTDSIDTLIKKGDTQWKIVDTAGIRRKKNV
KYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACIIVINKWDLVEKNSSTIYQVEKELRSKLYF
LHWSKMIFISALTGQRVDNIFEHALKAVNQHRRRVATSVVNEVLKESISWKSPPTKRSGKQGRLYYGTQVKNKPPTFTLF
VNDPKLFGITYRRYIEKQIRLNLGFEGTPLILLWRGKQQRALNKEVERGNIELVQKD
>Mature_457_residues
MILPTIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQIVDTGGLVFDDDSEFLPEIRAQVFLA
LEEASLALLVVDGNQGVTDGDLSIAKWLRNSSCKTIIAVNKCESTTLGISLASEFWKLGLGEPYPVSAIHGSGTGDLLDL
VIGELPENNIQEEEEKIMMSIIGRPNVGKSSLLNSISGEKRAIVSDISGTTTDSIDTLIKKGDTQWKIVDTAGIRRKKNV
KYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACIIVINKWDLVEKNSSTIYQVEKELRSKLYF
LHWSKMIFISALTGQRVDNIFEHALKAVNQHRRRVATSVVNEVLKESISWKSPPTKRSGKQGRLYYGTQVKNKPPTFTLF
VNDPKLFGITYRRYIEKQIRLNLGFEGTPLILLWRGKQQRALNKEVERGNIELVQKD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=474, Percent_Identity=35.4430379746835, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI2367268, Length=110, Percent_Identity=39.0909090909091, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788919, Length=167, Percent_Identity=32.3353293413174, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=123, Percent_Identity=39.0243902439024, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=205, Percent_Identity=33.6585365853659, Blast_Score=90, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51048; Mature: 51048

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILPTIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQIVDTGG
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCC
LVFDDDSEFLPEIRAQVFLALEEASLALLVVDGNQGVTDGDLSIAKWLRNSSCKTIIAVN
EEECCCHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEE
KCESTTLGISLASEFWKLGLGEPYPVSAIHGSGTGDLLDLVIGELPENNIQEEEEKIMMS
CCCCCEEHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
IIGRPNVGKSSLLNSISGEKRAIVSDISGTTTDSIDTLIKKGDTQWKIVDTAGIRRKKNV
HCCCCCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCC
KYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACIIVINKWDLV
CCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCEE
EKNSSTIYQVEKELRSKLYFLHWSKMIFISALTGQRVDNIFEHALKAVNQHRRRVATSVV
ECCCCHHHHHHHHHHHHEEEEEEHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NEVLKESISWKSPPTKRSGKQGRLYYGTQVKNKPPTFTLFVNDPKLFGITYRRYIEKQIR
HHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHHE
LNLGFEGTPLILLWRGKQQRALNKEVERGNIELVQKD
EECCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MILPTIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQIVDTGG
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCC
LVFDDDSEFLPEIRAQVFLALEEASLALLVVDGNQGVTDGDLSIAKWLRNSSCKTIIAVN
EEECCCHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEE
KCESTTLGISLASEFWKLGLGEPYPVSAIHGSGTGDLLDLVIGELPENNIQEEEEKIMMS
CCCCCEEHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
IIGRPNVGKSSLLNSISGEKRAIVSDISGTTTDSIDTLIKKGDTQWKIVDTAGIRRKKNV
HCCCCCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCC
KYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACIIVINKWDLV
CCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCEE
EKNSSTIYQVEKELRSKLYFLHWSKMIFISALTGQRVDNIFEHALKAVNQHRRRVATSVV
ECCCCHHHHHHHHHHHHEEEEEEHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NEVLKESISWKSPPTKRSGKQGRLYYGTQVKNKPPTFTLFVNDPKLFGITYRRYIEKQIR
HHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHHE
LNLGFEGTPLILLWRGKQQRALNKEVERGNIELVQKD
EECCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA