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The map label for this gene is fis [C]

Identifier: 78484785

GI number: 78484785

Start: 493629

End: 493892

Strand: Reverse

Name: fis [C]

Synonym: Tcr_0440

Alternate gene names: 78484785

Gene position: 493892-493629 (Counterclockwise)

Preceding gene: 78484786

Following gene: 78484784

Centisome position: 20.34

GC content: 39.39

Gene sequence:

>264_bases
ATGACATTACTATCTGATAAAAATCCAGCCAGCCAAGCACTCAGCACGCATGTCACCATGACGCTGAAAAACTATTTTGA
AACGCTGGAAGGTGAAGTACCGAGTGATGTTTATCAAATGGTGATAAGCCAAGTGGAACGCCCGCTCATTGAGTTTGTTT
TAAACGAGACCGCGTTTAATCAAAGTCGATCAGCCGAAATATTAGGTATTAACCGAAATACCTTAAGAAAGAAAATGCAG
CTTTATAAAATAACACCTGCATAA

Upstream 100 bases:

>100_bases
GCCAATACCTTCCGAACGGTACAGAGCTAAGAAAAAGATTTAATCGGCTTGAGAATACTCAGGCACAACTCAACTTAATC
AACCATTACTTTGATACTTT

Downstream 100 bases:

>100_bases
CGAATTCGCCTCTAGCAGGCACCCTTTTTACTGACTAACCAATTTTGGAGATAATTCCCTTATGAAACCTGTTCGCCGCG
CCCTGATTAGCGTCTCAGAT

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 86

Protein sequence:

>87_residues
MTLLSDKNPASQALSTHVTMTLKNYFETLEGEVPSDVYQMVISQVERPLIEFVLNETAFNQSRSAEILGINRNTLRKKMQ
LYKITPA

Sequences:

>Translated_87_residues
MTLLSDKNPASQALSTHVTMTLKNYFETLEGEVPSDVYQMVISQVERPLIEFVLNETAFNQSRSAEILGINRNTLRKKMQ
LYKITPA
>Mature_86_residues
TLLSDKNPASQALSTHVTMTLKNYFETLEGEVPSDVYQMVISQVERPLIEFVLNETAFNQSRSAEILGINRNTLRKKMQL
YKITPA

Specific function: Activates Ribosomal RNA Transcription. Plays A Direct Role In Upstream Activation Of rRNA Promoters. Binds To A Recombinational Enhancer Sequence That Is Required To Stimulate Hin-Mediated DNA Inversion. Prevents Initiation Of DNA Replication From Oric.

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family [H]

Homologues:

Organism=Escherichia coli, GI1789661, Length=71, Percent_Identity=45.0704225352113, Blast_Score=72, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197 [H]

Pfam domain/function: PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 9905; Mature: 9773

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLSDKNPASQALSTHVTMTLKNYFETLEGEVPSDVYQMVISQVERPLIEFVLNETAFN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QSRSAEILGINRNTLRKKMQLYKITPA
CCCCCEEEECCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLLSDKNPASQALSTHVTMTLKNYFETLEGEVPSDVYQMVISQVERPLIEFVLNETAFN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QSRSAEILGINRNTLRKKMQLYKITPA
CCCCCEEEECCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]