Click here to switch to the map view.

The map label for this gene is trkA [H]

Identifier: 78484532

GI number: 78484532

Start: 219221

End: 220618

Strand: Reverse

Name: trkA [H]

Synonym: Tcr_0187

Alternate gene names: 78484532

Gene position: 220618-219221 (Counterclockwise)

Preceding gene: 78484533

Following gene: 78484531

Centisome position: 9.09

GC content: 45.06

Gene sequence:

>1398_bases
ATGAACATAATTATTCTTGGTGCCGGACAAGTCGGTACATCACTTGCAGAGCTGCTTGCCATCGAAAACAATGATGTCAC
AGTGGTTGACCTTGATAGAACCAATCTTCAACGGTTACAAGATCGGTTGGACATTCGTACTGTGAATGGTCACGCCTCTA
ACCCAGACGTCTTAAACCAAGCCGGTTTGGAAGAAGCCGATATGTTGATCGCCGCCACACACGAAGATGACACCAATATC
GTTGCCTGTCAGTTGGCTCAGATCATGCATAAAACGCCCACCAAAATTGCGCGCGTTAGAAGTCAAAGCTACTTAAACCA
CCCTGAATTGTTTGATCGACAACAGAATACGGATGCGATCCCAATCAATGTTTTAATCAGCCCTGAAACGCTGGTTAAAA
ACTATATCCTGCAATTGATTAACTACCCGGGTTCGCTTCAAGTGGTTGATTTCTCAGAAGGGAAAGTTCGATTGGTCGCC
ATTCGGGCTCACTCTGGCGGCATGATTGTCGGCAAAAAAATTCGAGAAATTAAACACCATTTACCAGATGGCGTCCATCA
CAGGATTGTTGCTATCTATCGACGAGATGAAATCGTCATCCCAACCGGCAACGTCACCATTCAGGTTGGCGACGAAGTTT
TCTTTCTCGCCGAACCGTTCAATATTCCTAAAATTGTTCAGGAATTGCGACGTGATAAACTCCGCCCCTCAAGAAACATC
ATGATCGCAGGGGGAGGCAACATTGGCTTCAACCTCGCCAAAGAGTTGGAAAAAGAGCATCAGGTTAAAATTATCGACCA
CAATATGACGCAAGCACGGAAGATTTCTGAGCAGCTGGAGCAGTCCATTGTCATTCGAGGAGACGTTTCCGACAAATCCT
TGCTCATTGAAGAAAACATTGATGAAATCGATTTATTTTTAGCGCTGACGAATTCCGATGAAGCTAATATTATTTCAGGC
ATGCTGGCCAAAAAATTAGGCGTTCGTCGTGTCATTGCCTTGGTAAACAACCAGTCTTATGTGGATTTAATTCAACTGAA
CAGTATCGATGTCGCGATCTCAGCAGACCAGATCACCACGAGCCGCTTACTGCACTATATGCGTCAAGGCGATACCGTCA
AAGCGTTTACGTTGCGGCGAGGCGCAGCAGAAGCCATGGAAGTGATTGTGCATGGAAGCGAAAACTCTTCTGAGATTATT
GGAAAAACCATTGGGGAAATTCAATGGCCGACCAGCATTACCATTGGGTGCATTGTGCGTGAAAATGAAGTCCTGTTCTC
GCACCGAGATCTAACGATTGAAGCAGAAGACCATGTCATCCTTTTCTTGAATGATCCTAGCCAAGCGGGCCAAATTACAG
AGCTCTTTACACCAAAGGAAAAGAAAAGTTGGTTTTAA

Upstream 100 bases:

>100_bases
AAGATATGAACTGCAATCAATTGGTTACTTGGAAAGTGCAGGTAACACCATTTAAAATGCTTAGACAGCTTTCTAAGGAA
AATTTAAATAACGCGCCCTT

Downstream 100 bases:

>100_bases
TTTTTAAACAGTCCCGAGCTTATGCACAGTAAAATCATTTTAAAAGTCCTCGGTATTTTGTTGATGGTTTTCAGCTTAAC
GCTGATTCCTCCCTTTATCA

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MNIIILGAGQVGTSLAELLAIENNDVTVVDLDRTNLQRLQDRLDIRTVNGHASNPDVLNQAGLEEADMLIAATHEDDTNI
VACQLAQIMHKTPTKIARVRSQSYLNHPELFDRQQNTDAIPINVLISPETLVKNYILQLINYPGSLQVVDFSEGKVRLVA
IRAHSGGMIVGKKIREIKHHLPDGVHHRIVAIYRRDEIVIPTGNVTIQVGDEVFFLAEPFNIPKIVQELRRDKLRPSRNI
MIAGGGNIGFNLAKELEKEHQVKIIDHNMTQARKISEQLEQSIVIRGDVSDKSLLIEENIDEIDLFLALTNSDEANIISG
MLAKKLGVRRVIALVNNQSYVDLIQLNSIDVAISADQITTSRLLHYMRQGDTVKAFTLRRGAAEAMEVIVHGSENSSEII
GKTIGEIQWPTSITIGCIVRENEVLFSHRDLTIEAEDHVILFLNDPSQAGQITELFTPKEKKSWF

Sequences:

>Translated_465_residues
MNIIILGAGQVGTSLAELLAIENNDVTVVDLDRTNLQRLQDRLDIRTVNGHASNPDVLNQAGLEEADMLIAATHEDDTNI
VACQLAQIMHKTPTKIARVRSQSYLNHPELFDRQQNTDAIPINVLISPETLVKNYILQLINYPGSLQVVDFSEGKVRLVA
IRAHSGGMIVGKKIREIKHHLPDGVHHRIVAIYRRDEIVIPTGNVTIQVGDEVFFLAEPFNIPKIVQELRRDKLRPSRNI
MIAGGGNIGFNLAKELEKEHQVKIIDHNMTQARKISEQLEQSIVIRGDVSDKSLLIEENIDEIDLFLALTNSDEANIISG
MLAKKLGVRRVIALVNNQSYVDLIQLNSIDVAISADQITTSRLLHYMRQGDTVKAFTLRRGAAEAMEVIVHGSENSSEII
GKTIGEIQWPTSITIGCIVRENEVLFSHRDLTIEAEDHVILFLNDPSQAGQITELFTPKEKKSWF
>Mature_465_residues
MNIIILGAGQVGTSLAELLAIENNDVTVVDLDRTNLQRLQDRLDIRTVNGHASNPDVLNQAGLEEADMLIAATHEDDTNI
VACQLAQIMHKTPTKIARVRSQSYLNHPELFDRQQNTDAIPINVLISPETLVKNYILQLINYPGSLQVVDFSEGKVRLVA
IRAHSGGMIVGKKIREIKHHLPDGVHHRIVAIYRRDEIVIPTGNVTIQVGDEVFFLAEPFNIPKIVQELRRDKLRPSRNI
MIAGGGNIGFNLAKELEKEHQVKIIDHNMTQARKISEQLEQSIVIRGDVSDKSLLIEENIDEIDLFLALTNSDEANIISG
MLAKKLGVRRVIALVNNQSYVDLIQLNSIDVAISADQITTSRLLHYMRQGDTVKAFTLRRGAAEAMEVIVHGSENSSEII
GKTIGEIQWPTSITIGCIVRENEVLFSHRDLTIEAEDHVILFLNDPSQAGQITELFTPKEKKSWF

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=47.3799126637555, Blast_Score=440, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 51923; Mature: 51923

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIILGAGQVGTSLAELLAIENNDVTVVDLDRTNLQRLQDRLDIRTVNGHASNPDVLNQ
CEEEEEECCCHHHHHHHHHEECCCCEEEEECCCHHHHHHHHHCCEEEECCCCCCCCHHHH
AGLEEADMLIAATHEDDTNIVACQLAQIMHKTPTKIARVRSQSYLNHPELFDRQQNTDAI
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHCCCCCCCCE
PINVLISPETLVKNYILQLINYPGSLQVVDFSEGKVRLVAIRAHSGGMIVGKKIREIKHH
EEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCEEEHHHHHHHHHH
LPDGVHHRIVAIYRRDEIVIPTGNVTIQVGDEVFFLAEPFNIPKIVQELRRDKLRPSRNI
CCCCCCEEEEEEEECCEEEEECCCEEEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCE
MIAGGGNIGFNLAKELEKEHQVKIIDHNMTQARKISEQLEQSIVIRGDVSDKSLLIEENI
EEEECCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCEEEEECCCCCEEEEECCC
DEIDLFLALTNSDEANIISGMLAKKLGVRRVIALVNNQSYVDLIQLNSIDVAISADQITT
CEEEEEEEEECCCCHHHHHHHHHHHHHHHEEEHHHCCCCEEEEEEECCEEEEEECCHHHH
SRLLHYMRQGDTVKAFTLRRGAAEAMEVIVHGSENSSEIIGKTIGEIQWPTSITIGCIVR
HHHHHHHHCCCEEEEEEECCCHHHEEEEEEECCCCCHHHHHHHHCCEECCCCEEEEEEEE
ENEVLFSHRDLTIEAEDHVILFLNDPSQAGQITELFTPKEKKSWF
CCCEEEEECCEEEEECCEEEEEECCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MNIIILGAGQVGTSLAELLAIENNDVTVVDLDRTNLQRLQDRLDIRTVNGHASNPDVLNQ
CEEEEEECCCHHHHHHHHHEECCCCEEEEECCCHHHHHHHHHCCEEEECCCCCCCCHHHH
AGLEEADMLIAATHEDDTNIVACQLAQIMHKTPTKIARVRSQSYLNHPELFDRQQNTDAI
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHCCCCCCCCE
PINVLISPETLVKNYILQLINYPGSLQVVDFSEGKVRLVAIRAHSGGMIVGKKIREIKHH
EEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCEEEHHHHHHHHHH
LPDGVHHRIVAIYRRDEIVIPTGNVTIQVGDEVFFLAEPFNIPKIVQELRRDKLRPSRNI
CCCCCCEEEEEEEECCEEEEECCCEEEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCE
MIAGGGNIGFNLAKELEKEHQVKIIDHNMTQARKISEQLEQSIVIRGDVSDKSLLIEENI
EEEECCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCEEEEECCCCCEEEEECCC
DEIDLFLALTNSDEANIISGMLAKKLGVRRVIALVNNQSYVDLIQLNSIDVAISADQITT
CEEEEEEEEECCCCHHHHHHHHHHHHHHHEEEHHHCCCCEEEEEEECCEEEEEECCHHHH
SRLLHYMRQGDTVKAFTLRRGAAEAMEVIVHGSENSSEIIGKTIGEIQWPTSITIGCIVR
HHHHHHHHCCCEEEEEEECCCHHHEEEEEEECCCCCHHHHHHHHCCEECCCCEEEEEEEE
ENEVLFSHRDLTIEAEDHVILFLNDPSQAGQITELFTPKEKKSWF
CCCEEEEECCEEEEECCEEEEEECCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7948029; 9720051 [H]