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The map label for this gene is trkH [H]

Identifier: 78484531

GI number: 78484531

Start: 217748

End: 219199

Strand: Reverse

Name: trkH [H]

Synonym: Tcr_0186

Alternate gene names: 78484531

Gene position: 219199-217748 (Counterclockwise)

Preceding gene: 78484532

Following gene: 78484530

Centisome position: 9.03

GC content: 45.59

Gene sequence:

>1452_bases
ATGCACAGTAAAATCATTTTAAAAGTCCTCGGTATTTTGTTGATGGTTTTCAGCTTAACGCTGATTCCTCCCTTTATCAT
TGCCTTAATTTATCAAGATGGCGGAATGTCTGACTTTGGCTTTTCGGCCATAGGTCTTTTTATTACCGGATTTTTACTGT
GGTTTCCTTCTCGTAAAAGCCACCATGACTTAAAAATCCGAGATGGTTTTTTAATTGTCGTGATGTTTTGGACGGTACTC
GGATTTGCTGGTGCGGTTCCTATGTACTTTGCTTCCACAATCTATATTTCCCTGACGGATGCCATTTTTGAATCGTTTTC
AGGCTTGACGACCACAGGTGCGACGGTTATCAACGGCTTGGATGCTCTGCCTCATTCCTTGTTGTGGTATCGTCAGCAGC
TACAATGGCTAGGCGGGATGGGGATCATCGTTTTAGCCGTGGCCATCTTACCAATGCTTGGCATTGGGGGGATGCAACTC
TATCGTGCTGAAACACCCGGCCCGATCAAAGACAATAAACTGGCGCCTCGTATCTCTGAAACGGCGAAAGCGCTCTGGTA
CATTTATCTGGGGTTAACCATCGCTTGTGCTCTCGGTTACTGGCTCGCCGGAATGGATTGGTTTGATGCATTTGCTCACA
GTTTTTCAACCGTCGCCATTGGTGGATTTTCGACCCATGACGCCAGCATTGCGCACTTTGATGACGTCCATATCGAAATC
ATTGCCATGATTTTTATGTTTCTCGCCGCCATCAATTTTGCACTGCATTTCACCGCCTTCCGAAATTTATCAACACGGCC
CTACACTTTAGATCCTGAGTTCAAAGTTTTTTCAGCGTTGATCTTGGTCGGCATTGCCATCAGCAGCTTCTATCTGTACT
ACCAGGATGTTTATTTAACCTGGCAAGATGCCTTGCGATATGGTGCCTTTCAAACCATTTCGTTCGCATCAACAACCGGC
TTTGCCAATGCAGACTTTTCTTTATGGCCGATTTTCATTCCTTTCATGCTGATTATGATGAGTTTTATTGGCGGCTCTGC
CGGATCGACAGCCGGTGGAATGAAGGTCATTCGCTTTATCCTATTGGCCAAACAAGGAAGCCGTGAAATTCGACGCCTTC
TCCACCCAAATGCGTTGATGCCGGTGAAATTGCATGGCAAGCCCATTCCAGATAAAGTCATTACTTCTGTTTGGGGTTTC
TTTTCATTGTATGTTGTTTCTTTCGTTGGCATCATGCTGTTGTTGATGGCACTTGGACTAGACCAAACAACCGCTTTTTC
AACTGTCGCAGCCACTATTAACAACTTAGGACCTGCATTAGGACAAGCCGCAGCCAACTACCAGCACCTGTCCGATCCGG
TTAAGTGGGTGTTAACGTTCACGATGTTATTGGGCCGTTTGGAAATCTTCACCCTGCTGGTTCTCTTTACCTCTAGCTTC
TGGAGAAAATAA

Upstream 100 bases:

>100_bases
CCTTTTCTTGAATGATCCTAGCCAAGCGGGCCAAATTACAGAGCTCTTTACACCAAAGGAAAAGAAAAGTTGGTTTTAAT
TTTTAAACAGTCCCGAGCTT

Downstream 100 bases:

>100_bases
TGTCCCTTTCTTTATCTGAAAAATGGGATCAGAAGTATGCCGATGTCGATCCAAAAAAACCCGTGCCTCCTGCATGGGCA
TTGAAGCAACATCTTCGACA

Product: K+ transporter Trk

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MHSKIILKVLGILLMVFSLTLIPPFIIALIYQDGGMSDFGFSAIGLFITGFLLWFPSRKSHHDLKIRDGFLIVVMFWTVL
GFAGAVPMYFASTIYISLTDAIFESFSGLTTTGATVINGLDALPHSLLWYRQQLQWLGGMGIIVLAVAILPMLGIGGMQL
YRAETPGPIKDNKLAPRISETAKALWYIYLGLTIACALGYWLAGMDWFDAFAHSFSTVAIGGFSTHDASIAHFDDVHIEI
IAMIFMFLAAINFALHFTAFRNLSTRPYTLDPEFKVFSALILVGIAISSFYLYYQDVYLTWQDALRYGAFQTISFASTTG
FANADFSLWPIFIPFMLIMMSFIGGSAGSTAGGMKVIRFILLAKQGSREIRRLLHPNALMPVKLHGKPIPDKVITSVWGF
FSLYVVSFVGIMLLLMALGLDQTTAFSTVAATINNLGPALGQAAANYQHLSDPVKWVLTFTMLLGRLEIFTLLVLFTSSF
WRK

Sequences:

>Translated_483_residues
MHSKIILKVLGILLMVFSLTLIPPFIIALIYQDGGMSDFGFSAIGLFITGFLLWFPSRKSHHDLKIRDGFLIVVMFWTVL
GFAGAVPMYFASTIYISLTDAIFESFSGLTTTGATVINGLDALPHSLLWYRQQLQWLGGMGIIVLAVAILPMLGIGGMQL
YRAETPGPIKDNKLAPRISETAKALWYIYLGLTIACALGYWLAGMDWFDAFAHSFSTVAIGGFSTHDASIAHFDDVHIEI
IAMIFMFLAAINFALHFTAFRNLSTRPYTLDPEFKVFSALILVGIAISSFYLYYQDVYLTWQDALRYGAFQTISFASTTG
FANADFSLWPIFIPFMLIMMSFIGGSAGSTAGGMKVIRFILLAKQGSREIRRLLHPNALMPVKLHGKPIPDKVITSVWGF
FSLYVVSFVGIMLLLMALGLDQTTAFSTVAATINNLGPALGQAAANYQHLSDPVKWVLTFTMLLGRLEIFTLLVLFTSSF
WRK
>Mature_483_residues
MHSKIILKVLGILLMVFSLTLIPPFIIALIYQDGGMSDFGFSAIGLFITGFLLWFPSRKSHHDLKIRDGFLIVVMFWTVL
GFAGAVPMYFASTIYISLTDAIFESFSGLTTTGATVINGLDALPHSLLWYRQQLQWLGGMGIIVLAVAILPMLGIGGMQL
YRAETPGPIKDNKLAPRISETAKALWYIYLGLTIACALGYWLAGMDWFDAFAHSFSTVAIGGFSTHDASIAHFDDVHIEI
IAMIFMFLAAINFALHFTAFRNLSTRPYTLDPEFKVFSALILVGIAISSFYLYYQDVYLTWQDALRYGAFQTISFASTTG
FANADFSLWPIFIPFMLIMMSFIGGSAGSTAGGMKVIRFILLAKQGSREIRRLLHPNALMPVKLHGKPIPDKVITSVWGF
FSLYVVSFVGIMLLLMALGLDQTTAFSTVAATINNLGPALGQAAANYQHLSDPVKWVLTFTMLLGRLEIFTLLVLFTSSF
WRK

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=483, Percent_Identity=52.5879917184265, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1787626, Length=482, Percent_Identity=41.0788381742739, Blast_Score=390, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53469; Mature: 53469

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSKIILKVLGILLMVFSLTLIPPFIIALIYQDGGMSDFGFSAIGLFITGFLLWFPSRKS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
HHDLKIRDGFLIVVMFWTVLGFAGAVPMYFASTIYISLTDAIFESFSGLTTTGATVINGL
CCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DALPHSLLWYRQQLQWLGGMGIIVLAVAILPMLGIGGMQLYRAETPGPIKDNKLAPRISE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHH
TAKALWYIYLGLTIACALGYWLAGMDWFDAFAHSFSTVAIGGFSTHDASIAHFDDVHIEI
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEECCCCCCCCCHHHCCHHHHHH
IAMIFMFLAAINFALHFTAFRNLSTRPYTLDPEFKVFSALILVGIAISSFYLYYQDVYLT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQDALRYGAFQTISFASTTGFANADFSLWPIFIPFMLIMMSFIGGSAGSTAGGMKVIRFI
HHHHHHHCCHHEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LLAKQGSREIRRLLHPNALMPVKLHGKPIPDKVITSVWGFFSLYVVSFVGIMLLLMALGL
HHHHCCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DQTTAFSTVAATINNLGPALGQAAANYQHLSDPVKWVLTFTMLLGRLEIFTLLVLFTSSF
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRK
HCC
>Mature Secondary Structure
MHSKIILKVLGILLMVFSLTLIPPFIIALIYQDGGMSDFGFSAIGLFITGFLLWFPSRKS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
HHDLKIRDGFLIVVMFWTVLGFAGAVPMYFASTIYISLTDAIFESFSGLTTTGATVINGL
CCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DALPHSLLWYRQQLQWLGGMGIIVLAVAILPMLGIGGMQLYRAETPGPIKDNKLAPRISE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHH
TAKALWYIYLGLTIACALGYWLAGMDWFDAFAHSFSTVAIGGFSTHDASIAHFDDVHIEI
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEECCCCCCCCCHHHCCHHHHHH
IAMIFMFLAAINFALHFTAFRNLSTRPYTLDPEFKVFSALILVGIAISSFYLYYQDVYLT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQDALRYGAFQTISFASTTGFANADFSLWPIFIPFMLIMMSFIGGSAGSTAGGMKVIRFI
HHHHHHHCCHHEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LLAKQGSREIRRLLHPNALMPVKLHGKPIPDKVITSVWGFFSLYVVSFVGIMLLLMALGL
HHHHCCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DQTTAFSTVAATINNLGPALGQAAANYQHLSDPVKWVLTFTMLLGRLEIFTLLVLFTSSF
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRK
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]