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The map label for this gene is yrkH [H]

Identifier: 78484438

GI number: 78484438

Start: 119967

End: 120701

Strand: Reverse

Name: yrkH [H]

Synonym: Tcr_0093

Alternate gene names: 78484438

Gene position: 120701-119967 (Counterclockwise)

Preceding gene: 78484446

Following gene: 78484437

Centisome position: 4.97

GC content: 44.49

Gene sequence:

>735_bases
ATGTTTTTAGTTCAACGAGAAGTCCCCAGTGATCCATCTTCCATCTCGTATTTCATGGGGTGTGCAGGTCAAGGAAAGAG
TATAGCAATCGATGTTCATCAAGACGATGTGGACTGGTTTATCGAGCAAGCCGAACAAAAAGGTGTTGAGATCAATTATG
TAATTGATACACACATCCATGCCGATCATGTCTCAGGCGCTAAAGCGTTAGCTAAAAGCACCGGAGCAATTTATGCTCTT
CATGAATCCGCAACGCCACAGTTTGACTTTCACCCCCTCAAAGATCAAGAAACCTTTACGGCAGGAAATGTGAGCGTTGA
AGTACTTCACACGCCTGGTCACACGATGGACTCAATTTGTTTATTGGTGACGGATCTTTCACGCGGACCGGCCCCATGGT
TTTTGATTTCTCAACATACTTTATTTGTTGGCAGCGTAGGCAGGCCAGATTTAAGGGGCCGTGAAAAGGAAATGGCGGCT
CATTTATATGAATCAATCCACAGCAAAATCCTAACGCTACCAGATTATGTAGAAATCTTACCGGGTGCCAAAGCGGGCAG
TGTTTGTGGCGTTGGTTTATCGGCCAAACCTGTTTCCACCATCGGATATGAAAAGGCCAACAACGCAACCTTAAAATTGT
CCAGAACGGCGTTTATAGAAAAGGTACTGGAAGAGCTACCGCCGTTTCCAGAAAAGATGGATGAAATCATTCAAGCCAAC
ATTGAAAAAAGTTGA

Upstream 100 bases:

>100_bases
CAGCCTCGACCTGAGAATTCAAAATTGTCTTGCATTATAACAGCACATAAAATAACATTCAATTGATTGATTGATTATAA
AGACCGATAGGGAGCATGTT

Downstream 100 bases:

>100_bases
GCAGGAAGATTCAATCCTCTATATTATTCAATAAAATGGGCTGACAAAGGAAGACAACGTGTCCACGGTCAAAAAACAAT
TATTTGAACAACTGGCCTTA

Product: Beta-lactamase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MFLVQREVPSDPSSISYFMGCAGQGKSIAIDVHQDDVDWFIEQAEQKGVEINYVIDTHIHADHVSGAKALAKSTGAIYAL
HESATPQFDFHPLKDQETFTAGNVSVEVLHTPGHTMDSICLLVTDLSRGPAPWFLISQHTLFVGSVGRPDLRGREKEMAA
HLYESIHSKILTLPDYVEILPGAKAGSVCGVGLSAKPVSTIGYEKANNATLKLSRTAFIEKVLEELPPFPEKMDEIIQAN
IEKS

Sequences:

>Translated_244_residues
MFLVQREVPSDPSSISYFMGCAGQGKSIAIDVHQDDVDWFIEQAEQKGVEINYVIDTHIHADHVSGAKALAKSTGAIYAL
HESATPQFDFHPLKDQETFTAGNVSVEVLHTPGHTMDSICLLVTDLSRGPAPWFLISQHTLFVGSVGRPDLRGREKEMAA
HLYESIHSKILTLPDYVEILPGAKAGSVCGVGLSAKPVSTIGYEKANNATLKLSRTAFIEKVLEELPPFPEKMDEIIQAN
IEKS
>Mature_244_residues
MFLVQREVPSDPSSISYFMGCAGQGKSIAIDVHQDDVDWFIEQAEQKGVEINYVIDTHIHADHVSGAKALAKSTGAIYAL
HESATPQFDFHPLKDQETFTAGNVSVEVLHTPGHTMDSICLLVTDLSRGPAPWFLISQHTLFVGSVGRPDLRGREKEMAA
HLYESIHSKILTLPDYVEILPGAKAGSVCGVGLSAKPVSTIGYEKANNATLKLSRTAFIEKVLEELPPFPEKMDEIIQAN
IEKS

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=231, Percent_Identity=24.6753246753247, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787158, Length=193, Percent_Identity=29.0155440414508, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=229, Percent_Identity=27.0742358078603, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221330176, Length=242, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 26669; Mature: 26669

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLVQREVPSDPSSISYFMGCAGQGKSIAIDVHQDDVDWFIEQAEQKGVEINYVIDTHIH
CEEECCCCCCCCCHHHHEEECCCCCCEEEEEEECCHHHHHHHHHHHCCCEEEEEEECCEE
ADHVSGAKALAKSTGAIYALHESATPQFDFHPLKDQETFTAGNVSVEVLHTPGHTMDSIC
CCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEECCEEEEEEECCCCCHHHHE
LLVTDLSRGPAPWFLISQHTLFVGSVGRPDLRGREKEMAAHLYESIHSKILTLPDYVEIL
EEEEECCCCCCCEEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHC
PGAKAGSVCGVGLSAKPVSTIGYEKANNATLKLSRTAFIEKVLEELPPFPEKMDEIIQAN
CCCCCCCEEECCCCCCCCHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHC
IEKS
CCCC
>Mature Secondary Structure
MFLVQREVPSDPSSISYFMGCAGQGKSIAIDVHQDDVDWFIEQAEQKGVEINYVIDTHIH
CEEECCCCCCCCCHHHHEEECCCCCCEEEEEEECCHHHHHHHHHHHCCCEEEEEEECCEE
ADHVSGAKALAKSTGAIYALHESATPQFDFHPLKDQETFTAGNVSVEVLHTPGHTMDSIC
CCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEECCEEEEEEECCCCCHHHHE
LLVTDLSRGPAPWFLISQHTLFVGSVGRPDLRGREKEMAAHLYESIHSKILTLPDYVEIL
EEEEECCCCCCCEEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHC
PGAKAGSVCGVGLSAKPVSTIGYEKANNATLKLSRTAFIEKVLEELPPFPEKMDEIIQAN
CCCCCCCEEECCCCCCCCHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHC
IEKS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]