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The map label for this gene is arnB [H]

Identifier: 78358736

GI number: 78358736

Start: 3658671

End: 3659825

Strand: Direct

Name: arnB [H]

Synonym: Dde_3697

Alternate gene names: 78358736

Gene position: 3658671-3659825 (Clockwise)

Preceding gene: 78358735

Following gene: 78358737

Centisome position: 98.08

GC content: 64.76

Gene sequence:

>1155_bases
ATGAGCGATTCCAACCGTCACAACGCCCCGTTGCGCCTTTCCCGTTCCGTGGTGGGCAGGGAGGAGGCCGAGGCCGTCAC
CCGCATCATCATGGAAGAAGGCTATCTGGGCATGGGGGCCGAGGTTCAGCGCCTTGAAGCGGAAATTGCCGCCTATCTGG
GTGTGGCTGCCGCCAATGTAAGCTGCGTGAACACCGGCACCGCCGCGTTGCACCTTGCCGTGCAGGCTGCCGTGCCGCAG
GGCGGCGAGGTGCTGGTCCAGTCCGTCACCTATGTGGCTTCTTTTCAGGCCATACGCGCCGCCGGAGCGGTTCCCGTGGC
CTGCGAGGCTCTGCCCGCAAGCGTGACCATTGATCTGGACGACGCCGCCCGCCGTCTGACGCCGCGCACCAGAGCCATCA
TGCCGGTGCACTATGCAGGCTATGCGGGAGATCTGGATGCCGTATACGCCTTTGCGGACAGACACGGGCTGCGCGTCATC
GAAGACGCCGCCCATGCTTTCGGCAGCAGCCACAGAGGACGGCTCATCGGGTCATTCGGCGATATTGTGTGCTTCAGCTT
TGACGGTATCAAAAACATCACCTGCGGCGAAGGCGGCGCCATTGTCAGCGCAGACCCCGCCGTTAACGCCGCGGTAAAAG
ACGCCCGGCTGCTGGGGGTCGAACGGGACACGGAAAAACGGTTCGCCGGTCAGCGCAGCTGGAATTTTGATGTGACGGCG
CAAGGCTGGCGGTATCATATGAGCAACATCATGGCCGCCATCGGCAGAGTGCAGCTGCGCCGCCTGCCGCAGGAGTTCGC
TCCGGCCCGCCGCAGACTGAGCGCCCTGTACAGGGAACTGCTGCAGGATACCCCCGGGGTGGCCCTGCTGGAGACCGATG
CCGAAGGCACGGTGCCGCACATCATGGCCGTGCGCATCACCGACGGCCGCCGTGACACCCTGCGCGGACTGCTGGACGGC
GAAGGCCTGACCACAGGTCTGCATTACCGCCCCAACCACCTGCACACCCTGTTCGGAGGCGCAAGCCGGTCGCTGCCCGT
CAGTGAACGGCTGGAAAAGGAACTGCTCACCCTGCCGCTGCATCCGGCCCTTTCCGAGGATGACGTACGCGCCGTATGCA
CGCGGCTGCGCACATTCATGCAGGAGAACCGCTGA

Upstream 100 bases:

>100_bases
CAGGACGCGCCGTTCATTCCTTTCAGCTGGGCCGGAGCAGACCTTTCCGGCACGCCGGTCATGTAACGGCGGCTCCGGCC
GCATCAGTCAGGATAACAGC

Downstream 100 bases:

>100_bases
TGCAGCCTGATTCCGCCGCTGCTCCCGCCGTCAGCATCATCATGAACTGCCTGAACTGCAGCGTCCATCTGGCTGCGGCG
CTGGACAGCGTGCTGGCGCA

Product: aminotransferase

Products: NA

Alternate protein names: Polymyxin resistance protein pmrH; UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase; UDP-Ara4O aminotransferase; UDP-4-amino-4-deoxy-L-arabinose aminotransferase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSDSNRHNAPLRLSRSVVGREEAEAVTRIIMEEGYLGMGAEVQRLEAEIAAYLGVAAANVSCVNTGTAALHLAVQAAVPQ
GGEVLVQSVTYVASFQAIRAAGAVPVACEALPASVTIDLDDAARRLTPRTRAIMPVHYAGYAGDLDAVYAFADRHGLRVI
EDAAHAFGSSHRGRLIGSFGDIVCFSFDGIKNITCGEGGAIVSADPAVNAAVKDARLLGVERDTEKRFAGQRSWNFDVTA
QGWRYHMSNIMAAIGRVQLRRLPQEFAPARRRLSALYRELLQDTPGVALLETDAEGTVPHIMAVRITDGRRDTLRGLLDG
EGLTTGLHYRPNHLHTLFGGASRSLPVSERLEKELLTLPLHPALSEDDVRAVCTRLRTFMQENR

Sequences:

>Translated_384_residues
MSDSNRHNAPLRLSRSVVGREEAEAVTRIIMEEGYLGMGAEVQRLEAEIAAYLGVAAANVSCVNTGTAALHLAVQAAVPQ
GGEVLVQSVTYVASFQAIRAAGAVPVACEALPASVTIDLDDAARRLTPRTRAIMPVHYAGYAGDLDAVYAFADRHGLRVI
EDAAHAFGSSHRGRLIGSFGDIVCFSFDGIKNITCGEGGAIVSADPAVNAAVKDARLLGVERDTEKRFAGQRSWNFDVTA
QGWRYHMSNIMAAIGRVQLRRLPQEFAPARRRLSALYRELLQDTPGVALLETDAEGTVPHIMAVRITDGRRDTLRGLLDG
EGLTTGLHYRPNHLHTLFGGASRSLPVSERLEKELLTLPLHPALSEDDVRAVCTRLRTFMQENR
>Mature_383_residues
SDSNRHNAPLRLSRSVVGREEAEAVTRIIMEEGYLGMGAEVQRLEAEIAAYLGVAAANVSCVNTGTAALHLAVQAAVPQG
GEVLVQSVTYVASFQAIRAAGAVPVACEALPASVTIDLDDAARRLTPRTRAIMPVHYAGYAGDLDAVYAFADRHGLRVIE
DAAHAFGSSHRGRLIGSFGDIVCFSFDGIKNITCGEGGAIVSADPAVNAAVKDARLLGVERDTEKRFAGQRSWNFDVTAQ
GWRYHMSNIMAAIGRVQLRRLPQEFAPARRRLSALYRELLQDTPGVALLETDAEGTVPHIMAVRITDGRRDTLRGLLDGE
GLTTGLHYRPNHLHTLFGGASRSLPVSERLEKELLTLPLHPALSEDDVRAVCTRLRTFMQENR

Specific function: Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family. ArnB subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=375, Percent_Identity=33.3333333333333, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI2367285, Length=366, Percent_Identity=30.6010928961749, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022850
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: =2.6.1.87 [H]

Molecular weight: Translated: 41571; Mature: 41440

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSNRHNAPLRLSRSVVGREEAEAVTRIIMEEGYLGMGAEVQRLEAEIAAYLGVAAANV
CCCCCCCCCCCEEHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCE
SCVNTGTAALHLAVQAAVPQGGEVLVQSVTYVASFQAIRAAGAVPVACEALPASVTIDLD
EEECCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHCCCCCEEEEECC
DAARRLTPRTRAIMPVHYAGYAGDLDAVYAFADRHGLRVIEDAAHAFGSSHRGRLIGSFG
HHHHHCCCCHHEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEECCC
DIVCFSFDGIKNITCGEGGAIVSADPAVNAAVKDARLLGVERDTEKRFAGQRSWNFDVTA
CEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEC
QGWRYHMSNIMAAIGRVQLRRLPQEFAPARRRLSALYRELLQDTPGVALLETDAEGTVPH
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCE
IMAVRITDGRRDTLRGLLDGEGLTTGLHYRPNHLHTLFGGASRSLPVSERLEKELLTLPL
EEEEEECCCCHHHHHHHHCCCCCEECCCCCCCCHHHEECCCCCCCCHHHHHHHHHHCCCC
HPALSEDDVRAVCTRLRTFMQENR
CCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDSNRHNAPLRLSRSVVGREEAEAVTRIIMEEGYLGMGAEVQRLEAEIAAYLGVAAANV
CCCCCCCCCCEEHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCE
SCVNTGTAALHLAVQAAVPQGGEVLVQSVTYVASFQAIRAAGAVPVACEALPASVTIDLD
EEECCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHCCCCCEEEEECC
DAARRLTPRTRAIMPVHYAGYAGDLDAVYAFADRHGLRVIEDAAHAFGSSHRGRLIGSFG
HHHHHCCCCHHEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEECCC
DIVCFSFDGIKNITCGEGGAIVSADPAVNAAVKDARLLGVERDTEKRFAGQRSWNFDVTA
CEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEC
QGWRYHMSNIMAAIGRVQLRRLPQEFAPARRRLSALYRELLQDTPGVALLETDAEGTVPH
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCE
IMAVRITDGRRDTLRGLLDGEGLTTGLHYRPNHLHTLFGGASRSLPVSERLEKELLTLPL
EEEEEECCCCHHHHHHHHCCCCCEECCCCCCCCHHHEECCCCCCCCHHHHHHHHHHCCCC
HPALSEDDVRAVCTRLRTFMQENR
CCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA