Click here to switch to the map view.

The map label for this gene is paaK [H]

Identifier: 78358584

GI number: 78358584

Start: 3505081

End: 3506655

Strand: Direct

Name: paaK [H]

Synonym: Dde_3545

Alternate gene names: 78358584

Gene position: 3505081-3506655 (Clockwise)

Preceding gene: 78358583

Following gene: 78358585

Centisome position: 93.96

GC content: 66.29

Gene sequence:

>1575_bases
ATGACAGCAGACCGCAGCGTGTTGCCCCGGCAATGCCGCGGACAGGCAGGCATGCCGCATGAAGCCCCGCACACAGCCCC
GCCGTGCTGCGCCGGACCGGACAGGGAAAATCACAGCGGAAAAGACAGCACGGGCAGCGATGCAGGCAGCGATGCAGAAG
GACAGCGCAATCAGGCGGTGTTCACTCCGGACGGGCTGACGGCCCGGGCCATGGGAATTTCCTGCGCCGCGGCCTGCAAT
CCCGCATGCAGCGATCCGGAGCTGCGCAGGCTGCTCACGGCTTCCGGCATAAGCGCATGGCAGACAGACAGACTGCGCGA
GGTACTCGCCCTCGCCGCAGAGGCTTCACCCTATTACAGACAAGCCCTGCAGGGTGTGGACCCGGCAAGCATCAGCGCGC
GCGGGGGGCTGCACCGCCTTCCTCTGCTGCATGCCGATGTGCTGCGCCGCGCACCTCTGAGCCTGCTGTGCACCTCGCAG
GATGACGTGGCGCGGGTGGTCACGCTGGACACATCGGGCACGTCCGGCCGGCCAAAGCGGCTTTTCTTTTCTGAAGAAGA
CCTGAACGCCACGGTGGAATTTTTTTCGTGGGGCATGCTGAGCGTGGGGCATCCCGGCGATACCGTGCTGGCTGTCCTGC
CGGGAGAACGCCCCGCCAGTGTGGGGCGCCTGCTGGGTACCGCGCTGGAAAACGCAGGCATGCGCTCCGTGGCCGGCAAT
ATGGGGCAGGGCGCTCCGGCGCTGGCACGGCTGGCCCATACGGAAAAAGCCGCAGTGATTGTCGGGTCGGCCAGCCATGT
CAGGCATCTGGCACTGGCCTGGCAGCAAGCCGGTTACGACCCCGGCAGCATTCACACGGTGCTGCTGTGCTGGGACAGCG
TGCCCCCCGCGGTGGCCGGACTCATACGCCGCATTTTCGGCTGCAGAGTGCTTGTCCACTGGGGCATGACGGAAACAGGT
CTGGGCGGAGCGCTGGGCTGCGGACATCAGGGACTGCACCTGCGCGAAGCCGACCTGCTGGCCGAAGTGATAGATCCCGT
TACCGGCACCCCCCTGCCCGACGGACAGGAGGGAGAACTGGTCATCACCACCCTGCGCCGCCGCACCATGCCGCTCATAC
GCTACCGTACCGGCGATCTGGCGCGGCTGCTTGCCGGTGCATGCCCCTGCGGCAGCCCGCTGAGACGCATCAGCCCCGGC
AGGGGCAGAACCGGCGAAGGAATCACACTGCCGGACGGCGGCAGCCTGTACCCTGCCGATCTGGACAACATTCTTCTGCC
CCTTGCCGGGCTGCATGATTTTGAAGCATGCTGGCAGCCGTGGGCCGGTACCCCGCTGCAAATCACGCTGTACCCCGCGC
CGGCAGCCGGTACGGACCGGACGCTGCGGCAGCAGGCAGAAAAAGCGCTGGCGGATTCACCCCTGCCTGCGGCTCTGACA
CGCCACGGCGGGACAATGTTCCATGTCGCCCGCACCGCACCGCAGGCGGGTTTCGGCAAACGCCGTATCCGCGTCATTCC
ACAGGGCACGCCACCTCTCAACTCCGGAGAATCATACCATGAACAGCTTCCTTGA

Upstream 100 bases:

>100_bases
GATGCTGCATCCATGTGGCCGCTCCGGACGGGCGCATAGTGCCTTTCTGCGCATGGAACTGCACCAGTGCGCTGGGAGTG
CCCCTGCACAGGAGCGGACA

Downstream 100 bases:

>100_bases
TTCTGTATGCGCACTTCTTGAACAGGGCGAAGATGTGGTCATTGTGACCATTGCCATGCAGTCCGGTTCCACCCCGCGGG
AAAGCGGTGCCAAAATGGCC

Product: coenzyme F390 synthetase-like

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MTADRSVLPRQCRGQAGMPHEAPHTAPPCCAGPDRENHSGKDSTGSDAGSDAEGQRNQAVFTPDGLTARAMGISCAAACN
PACSDPELRRLLTASGISAWQTDRLREVLALAAEASPYYRQALQGVDPASISARGGLHRLPLLHADVLRRAPLSLLCTSQ
DDVARVVTLDTSGTSGRPKRLFFSEEDLNATVEFFSWGMLSVGHPGDTVLAVLPGERPASVGRLLGTALENAGMRSVAGN
MGQGAPALARLAHTEKAAVIVGSASHVRHLALAWQQAGYDPGSIHTVLLCWDSVPPAVAGLIRRIFGCRVLVHWGMTETG
LGGALGCGHQGLHLREADLLAEVIDPVTGTPLPDGQEGELVITTLRRRTMPLIRYRTGDLARLLAGACPCGSPLRRISPG
RGRTGEGITLPDGGSLYPADLDNILLPLAGLHDFEACWQPWAGTPLQITLYPAPAAGTDRTLRQQAEKALADSPLPAALT
RHGGTMFHVARTAPQAGFGKRRIRVIPQGTPPLNSGESYHEQLP

Sequences:

>Translated_524_residues
MTADRSVLPRQCRGQAGMPHEAPHTAPPCCAGPDRENHSGKDSTGSDAGSDAEGQRNQAVFTPDGLTARAMGISCAAACN
PACSDPELRRLLTASGISAWQTDRLREVLALAAEASPYYRQALQGVDPASISARGGLHRLPLLHADVLRRAPLSLLCTSQ
DDVARVVTLDTSGTSGRPKRLFFSEEDLNATVEFFSWGMLSVGHPGDTVLAVLPGERPASVGRLLGTALENAGMRSVAGN
MGQGAPALARLAHTEKAAVIVGSASHVRHLALAWQQAGYDPGSIHTVLLCWDSVPPAVAGLIRRIFGCRVLVHWGMTETG
LGGALGCGHQGLHLREADLLAEVIDPVTGTPLPDGQEGELVITTLRRRTMPLIRYRTGDLARLLAGACPCGSPLRRISPG
RGRTGEGITLPDGGSLYPADLDNILLPLAGLHDFEACWQPWAGTPLQITLYPAPAAGTDRTLRQQAEKALADSPLPAALT
RHGGTMFHVARTAPQAGFGKRRIRVIPQGTPPLNSGESYHEQLP
>Mature_523_residues
TADRSVLPRQCRGQAGMPHEAPHTAPPCCAGPDRENHSGKDSTGSDAGSDAEGQRNQAVFTPDGLTARAMGISCAAACNP
ACSDPELRRLLTASGISAWQTDRLREVLALAAEASPYYRQALQGVDPASISARGGLHRLPLLHADVLRRAPLSLLCTSQD
DVARVVTLDTSGTSGRPKRLFFSEEDLNATVEFFSWGMLSVGHPGDTVLAVLPGERPASVGRLLGTALENAGMRSVAGNM
GQGAPALARLAHTEKAAVIVGSASHVRHLALAWQQAGYDPGSIHTVLLCWDSVPPAVAGLIRRIFGCRVLVHWGMTETGL
GGALGCGHQGLHLREADLLAEVIDPVTGTPLPDGQEGELVITTLRRRTMPLIRYRTGDLARLLAGACPCGSPLRRISPGR
GRTGEGITLPDGGSLYPADLDNILLPLAGLHDFEACWQPWAGTPLQITLYPAPAAGTDRTLRQQAEKALADSPLPAALTR
HGGTMFHVARTAPQAGFGKRRIRVIPQGTPPLNSGESYHEQLP

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=346, Percent_Identity=27.7456647398844, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 55340; Mature: 55208

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADRSVLPRQCRGQAGMPHEAPHTAPPCCAGPDRENHSGKDSTGSDAGSDAEGQRNQAV
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
FTPDGLTARAMGISCAAACNPACSDPELRRLLTASGISAWQTDRLREVLALAAEASPYYR
ECCCCCEEHHHCCCHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
QALQGVDPASISARGGLHRLPLLHADVLRRAPLSLLCTSQDDVARVVTLDTSGTSGRPKR
HHHCCCCCCCCCCCCCCHHCHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCCCE
LFFSEEDLNATVEFFSWGMLSVGHPGDTVLAVLPGERPASVGRLLGTALENAGMRSVAGN
EEECCCCCCCEEHHHHCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHCC
MGQGAPALARLAHTEKAAVIVGSASHVRHLALAWQQAGYDPGSIHTVLLCWDSVPPAVAG
CCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHH
LIRRIFGCRVLVHWGMTETGLGGALGCGHQGLHLREADLLAEVIDPVTGTPLPDGQEGEL
HHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCE
VITTLRRRTMPLIRYRTGDLARLLAGACPCGSPLRRISPGRGRTGEGITLPDGGSLYPAD
EEEEHHHHCCCEEEECCCHHHHHHHCCCCCCCCHHHCCCCCCCCCCCEECCCCCCCCCCC
LDNILLPLAGLHDFEACWQPWAGTPLQITLYPAPAAGTDRTLRQQAEKALADSPLPAALT
HHHHHHHHCCCCHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHH
RHGGTMFHVARTAPQAGFGKRRIRVIPQGTPPLNSGESYHEQLP
HCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCC
>Mature Secondary Structure 
TADRSVLPRQCRGQAGMPHEAPHTAPPCCAGPDRENHSGKDSTGSDAGSDAEGQRNQAV
CCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
FTPDGLTARAMGISCAAACNPACSDPELRRLLTASGISAWQTDRLREVLALAAEASPYYR
ECCCCCEEHHHCCCHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
QALQGVDPASISARGGLHRLPLLHADVLRRAPLSLLCTSQDDVARVVTLDTSGTSGRPKR
HHHCCCCCCCCCCCCCCHHCHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCCCE
LFFSEEDLNATVEFFSWGMLSVGHPGDTVLAVLPGERPASVGRLLGTALENAGMRSVAGN
EEECCCCCCCEEHHHHCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHCC
MGQGAPALARLAHTEKAAVIVGSASHVRHLALAWQQAGYDPGSIHTVLLCWDSVPPAVAG
CCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHH
LIRRIFGCRVLVHWGMTETGLGGALGCGHQGLHLREADLLAEVIDPVTGTPLPDGQEGEL
HHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCE
VITTLRRRTMPLIRYRTGDLARLLAGACPCGSPLRRISPGRGRTGEGITLPDGGSLYPAD
EEEEHHHHCCCEEEECCCHHHHHHHCCCCCCCCHHHCCCCCCCCCCCEECCCCCCCCCCC
LDNILLPLAGLHDFEACWQPWAGTPLQITLYPAPAAGTDRTLRQQAEKALADSPLPAALT
HHHHHHHHCCCCHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHH
RHGGTMFHVARTAPQAGFGKRRIRVIPQGTPPLNSGESYHEQLP
HCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]