Click here to switch to the map view.

The map label for this gene is bdhA [H]

Identifier: 78358166

GI number: 78358166

Start: 3119062

End: 3120231

Strand: Direct

Name: bdhA [H]

Synonym: Dde_3126

Alternate gene names: 78358166

Gene position: 3119062-3120231 (Clockwise)

Preceding gene: 78358165

Following gene: 78358173

Centisome position: 83.62

GC content: 61.37

Gene sequence:

>1170_bases
ATGGACAACTTCATATACCACGCGCCCACGCGCATCGTCTTCGGCAGAAATACCGTATCGCAAACCGGTGCGGAACTGGC
GGCACACAATGTGCGCCGCACGCTGCTGGTCACCGGCGGCAGCGCCGCCATGCGTACCGGAGCATACGCACAGGTCACGG
CTTCACTGGACGGGGCCGGTGTGATGCATACGCTTTTCAGCGGTGTCACGCCCAATCCTTCCCTTGATCTTGTGGAAAAA
GGCATAGCCGCCGCACACGCGTTTGCGGTGGACAGCGTGCTGGCCATCGGCGGCGGCAGTGTCATAGACTGCGCCAAAGC
CATTGCCGCCGGTGTTTTTCTAGAAGATTACTGGGCACAGGTGGAAACACGGCGTCCCGTCACACAGGCTCTGCCTGTAT
TCACGGTGCTCACTCTTTCGGGCACCGGTTCGGAAATGAACGAAAAAGCCGTCATCACCAACGAACCGCTGGCCAGAAAA
TGGTCGCTGAGCGGCCTGTGCCTGTGCCCCAGAGTATCCATCATCGACCCGCAGCTCCAGTCCTCCGTTCCGTGGCATCT
GACCGCCGCGGGCGGCATCGATGCCATGACCCATGTGATGGAAAACTACTTCCGCGGCAGAACGGCCCGCGCAGCCACCG
GTTACTTTCAGGAAGAGACAACTCTGCAGCTGTGCGAGGGAATCCTGCGCGCCATCATCATGTCACTGGATGAACTGCAG
CGCGACGGCTCGGACTATACCGCGCGGGCCAATCTGGCATGGGCAGCCAGCTGGGGGCTTAACGGCCTTTCAGGCTCGGG
GCTTTCCGGCGGCGACTGGACTTCGCACGCTCTGGAACACGCCCTGAGCGGACTGCACCCGCAGGTTCCCCACGGTGAAG
GACTGGCGGTGATTTTCCCCTCGTGGATGGAGCAGGTCTGCCACAGCGTGCCGGACATCTTCACGCGTTTTGCCCGCACC
ATATGGGGTGTTTCCACAGCGGAAGAAGGAGTGGCCGCAACCCGTCAGGCATTCTCGCGCTGGGGGGCTCCCGACCGTCT
GTCCCGCTGGAGCATTCCCGCATCCGACATTCCCCGTATGGTACAGAATGCCCTGAGCTACCGCGCGCTGGGCAGAATAG
TGCCTCTTTCGGCAGAAGATGTGACCAGCATATACACGCGGGTGCTCTGA

Upstream 100 bases:

>100_bases
GGAAGCTTGCAGTACCAGCCGGCTCCGAACGGGTCATAAGCCACGCCGTAACGGTCACCGCCCCCGAAGACACCCCTGTG
GACGCCGGAAGAAAACAGTA

Downstream 100 bases:

>100_bases
CCCCGCTGCCGCATATATAAAAAAGGGCTTTCCGCAAAAGCGGAAAGCCCTTTTTTCCGTACAGCGGCACGGCCGCCGTG
CAGATACCCTTTAAAGGCTG

Product: alcohol dehydrogenase, iron-containing

Products: NA

Alternate protein names: BDH I [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDNFIYHAPTRIVFGRNTVSQTGAELAAHNVRRTLLVTGGSAAMRTGAYAQVTASLDGAGVMHTLFSGVTPNPSLDLVEK
GIAAAHAFAVDSVLAIGGGSVIDCAKAIAAGVFLEDYWAQVETRRPVTQALPVFTVLTLSGTGSEMNEKAVITNEPLARK
WSLSGLCLCPRVSIIDPQLQSSVPWHLTAAGGIDAMTHVMENYFRGRTARAATGYFQEETTLQLCEGILRAIIMSLDELQ
RDGSDYTARANLAWAASWGLNGLSGSGLSGGDWTSHALEHALSGLHPQVPHGEGLAVIFPSWMEQVCHSVPDIFTRFART
IWGVSTAEEGVAATRQAFSRWGAPDRLSRWSIPASDIPRMVQNALSYRALGRIVPLSAEDVTSIYTRVL

Sequences:

>Translated_389_residues
MDNFIYHAPTRIVFGRNTVSQTGAELAAHNVRRTLLVTGGSAAMRTGAYAQVTASLDGAGVMHTLFSGVTPNPSLDLVEK
GIAAAHAFAVDSVLAIGGGSVIDCAKAIAAGVFLEDYWAQVETRRPVTQALPVFTVLTLSGTGSEMNEKAVITNEPLARK
WSLSGLCLCPRVSIIDPQLQSSVPWHLTAAGGIDAMTHVMENYFRGRTARAATGYFQEETTLQLCEGILRAIIMSLDELQ
RDGSDYTARANLAWAASWGLNGLSGSGLSGGDWTSHALEHALSGLHPQVPHGEGLAVIFPSWMEQVCHSVPDIFTRFART
IWGVSTAEEGVAATRQAFSRWGAPDRLSRWSIPASDIPRMVQNALSYRALGRIVPLSAEDVTSIYTRVL
>Mature_389_residues
MDNFIYHAPTRIVFGRNTVSQTGAELAAHNVRRTLLVTGGSAAMRTGAYAQVTASLDGAGVMHTLFSGVTPNPSLDLVEK
GIAAAHAFAVDSVLAIGGGSVIDCAKAIAAGVFLEDYWAQVETRRPVTQALPVFTVLTLSGTGSEMNEKAVITNEPLARK
WSLSGLCLCPRVSIIDPQLQSSVPWHLTAAGGIDAMTHVMENYFRGRTARAATGYFQEETTLQLCEGILRAIIMSLDELQ
RDGSDYTARANLAWAASWGLNGLSGSGLSGGDWTSHALEHALSGLHPQVPHGEGLAVIFPSWMEQVCHSVPDIFTRFART
IWGVSTAEEGVAATRQAFSRWGAPDRLSRWSIPASDIPRMVQNALSYRALGRIVPLSAEDVTSIYTRVL

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=415, Percent_Identity=22.6506024096386, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789386, Length=373, Percent_Identity=30.2949061662198, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI48994951, Length=398, Percent_Identity=29.3969849246231, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789163, Length=386, Percent_Identity=28.4974093264249, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI87082107, Length=347, Percent_Identity=29.971181556196, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787493, Length=331, Percent_Identity=27.7945619335347, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17537053, Length=415, Percent_Identity=23.855421686747, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321181, Length=392, Percent_Identity=26.530612244898, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24657991, Length=427, Percent_Identity=23.1850117096019, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 41707; Mature: 41707

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNFIYHAPTRIVFGRNTVSQTGAELAAHNVRRTLLVTGGSAAMRTGAYAQVTASLDGAG
CCCCEEECCCEEEECCCHHHHHHHHHHHHHHCEEEEEECCHHHHHCCCCEEEEECCCCCH
VMHTLFSGVTPNPSLDLVEKGIAAAHAFAVDSVLAIGGGSVIDCAKAIAAGVFLEDYWAQ
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VETRRPVTQALPVFTVLTLSGTGSEMNEKAVITNEPLARKWSLSGLCLCPRVSIIDPQLQ
HHCCCCHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCHHCCCCCEEECCCCCEECCHHH
SSVPWHLTAAGGIDAMTHVMENYFRGRTARAATGYFQEETTLQLCEGILRAIIMSLDELQ
CCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RDGSDYTARANLAWAASWGLNGLSGSGLSGGDWTSHALEHALSGLHPQVPHGEGLAVIFP
HCCCCCEEECCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECH
SWMEQVCHSVPDIFTRFARTIWGVSTAEEGVAATRQAFSRWGAPDRLSRWSIPASDIPRM
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
VQNALSYRALGRIVPLSAEDVTSIYTRVL
HHHHHHHHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MDNFIYHAPTRIVFGRNTVSQTGAELAAHNVRRTLLVTGGSAAMRTGAYAQVTASLDGAG
CCCCEEECCCEEEECCCHHHHHHHHHHHHHHCEEEEEECCHHHHHCCCCEEEEECCCCCH
VMHTLFSGVTPNPSLDLVEKGIAAAHAFAVDSVLAIGGGSVIDCAKAIAAGVFLEDYWAQ
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VETRRPVTQALPVFTVLTLSGTGSEMNEKAVITNEPLARKWSLSGLCLCPRVSIIDPQLQ
HHCCCCHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCHHCCCCCEEECCCCCEECCHHH
SSVPWHLTAAGGIDAMTHVMENYFRGRTARAATGYFQEETTLQLCEGILRAIIMSLDELQ
CCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RDGSDYTARANLAWAASWGLNGLSGSGLSGGDWTSHALEHALSGLHPQVPHGEGLAVIFP
HCCCCCEEECCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECH
SWMEQVCHSVPDIFTRFARTIWGVSTAEEGVAATRQAFSRWGAPDRLSRWSIPASDIPRM
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
VQNALSYRALGRIVPLSAEDVTSIYTRVL
HHHHHHHHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385386; 11466286; 1809209 [H]