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The map label for this gene is cheV [H]

Identifier: 78358108

GI number: 78358108

Start: 3059442

End: 3060389

Strand: Direct

Name: cheV [H]

Synonym: Dde_3068

Alternate gene names: 78358108

Gene position: 3059442-3060389 (Clockwise)

Preceding gene: 78358107

Following gene: 78358113

Centisome position: 82.02

GC content: 57.38

Gene sequence:

>948_bases
ATGAGTTCCGAACACAATATTCTGCTGGAAGCAGGCACAAACGAGCTGGAAGTGCTGGAGCTGTTTCTGAACCATCGTAC
AGACACCGGCCAGCAGGCCTGCTATCTGGGAGTCAATGTGGCCAAAGTGATGCAGGTTATCGAGGCTCCGGCTCTGGATT
CGCCGGAATCAGCCACCAACCCGTGTTTCATGGGCATTATTCCCCTGCGCGGCCTTACAGTGCCGGTTCTTGATCTGGGC
AAATGGCTGGGGCTTGATGTGGTGCGGCACAAACACGATGTGATCATGGTCACCCAGTTCAGCGGAACCACCACCGGATT
TCTGGTTTCCGGCGTGACGGATATCCACAGAGTGGGCTGGCAGTCGGTGCAGCCTCCGGGACGTTTTCTCGCGGGTATCG
GGGCCGATTCTGTGGTGGGCATAGTCAAAATGGATGATAAATTCATCCAGCTGGTGGATCTTGAGCACATCATCGCCGAT
CTGGACGCCTCCACCCGCGGGCAGGTAGGCACGGGGGTGACGGCCCCCAGACGCTACAAAGCCATAGTCAGCGATGATTC
CCCCTCCATCCGCAACATGCTTGTGGCCAACCTGAAGGCCGCCAACATAGAACCCATGATAGCCACCAACGGGCAGGAAG
CCCTGACCATGCTGCGCGCCGAAGCGGCAAGAGCCGAAGAGGAAAACCGCCCGCTGTCCGACTTTGTCGATATTCTCATA
TCCGACATTGAAATGCCGCTGATGGACGGCCTGTCGCTGACCAAGACCATCAAGCAGGACCCGCTGACCAGAAACGTGCC
CGTCATCCTGTACTCGTCGCTCATCACACCGGAACTGCGGCATAAAGGCGAATCTGTGGGCGCTGACGATCAGATTTCCA
AACCCGACCTTGCCAGCATGGCCCAGCGCATCATCTCGCTGCTGCAGGAAAAAGAAAGACCGGCCTGA

Upstream 100 bases:

>100_bases
CAGATAGACCGCTGGCGGCAGCACATCTGCCAGATAGCGGAATAACACCGGCACGGATCTTCCGGCGCCGTTACGTCACC
TCTCCGCAACAGGGGGTAGC

Downstream 100 bases:

>100_bases
CCCCGCAGGGCGGGCTTTGTCCGGCAGCCGGCCGCAGCAGTCCCGCGGAAAAACGCACCGCGCCGTATCAGGCCCGCCAG
CGCAGCCGCGCTTCCACCTT

Product: CheW protein

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSSEHNILLEAGTNELEVLELFLNHRTDTGQQACYLGVNVAKVMQVIEAPALDSPESATNPCFMGIIPLRGLTVPVLDLG
KWLGLDVVRHKHDVIMVTQFSGTTTGFLVSGVTDIHRVGWQSVQPPGRFLAGIGADSVVGIVKMDDKFIQLVDLEHIIAD
LDASTRGQVGTGVTAPRRYKAIVSDDSPSIRNMLVANLKAANIEPMIATNGQEALTMLRAEAARAEEENRPLSDFVDILI
SDIEMPLMDGLSLTKTIKQDPLTRNVPVILYSSLITPELRHKGESVGADDQISKPDLASMAQRIISLLQEKERPA

Sequences:

>Translated_315_residues
MSSEHNILLEAGTNELEVLELFLNHRTDTGQQACYLGVNVAKVMQVIEAPALDSPESATNPCFMGIIPLRGLTVPVLDLG
KWLGLDVVRHKHDVIMVTQFSGTTTGFLVSGVTDIHRVGWQSVQPPGRFLAGIGADSVVGIVKMDDKFIQLVDLEHIIAD
LDASTRGQVGTGVTAPRRYKAIVSDDSPSIRNMLVANLKAANIEPMIATNGQEALTMLRAEAARAEEENRPLSDFVDILI
SDIEMPLMDGLSLTKTIKQDPLTRNVPVILYSSLITPELRHKGESVGADDQISKPDLASMAQRIISLLQEKERPA
>Mature_314_residues
SSEHNILLEAGTNELEVLELFLNHRTDTGQQACYLGVNVAKVMQVIEAPALDSPESATNPCFMGIIPLRGLTVPVLDLGK
WLGLDVVRHKHDVIMVTQFSGTTTGFLVSGVTDIHRVGWQSVQPPGRFLAGIGADSVVGIVKMDDKFIQLVDLEHIIADL
DASTRGQVGTGVTAPRRYKAIVSDDSPSIRNMLVANLKAANIEPMIATNGQEALTMLRAEAARAEEENRPLSDFVDILIS
DIEMPLMDGLSLTKTIKQDPLTRNVPVILYSSLITPELRHKGESVGADDQISKPDLASMAQRIISLLQEKERPA

Specific function: Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW function together to couple CheA activation to methyl-accepting chemotaxis protein receptor status and possible CheA-dependent phosphoryl

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 34249; Mature: 34118

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50851 CHEW ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEHNILLEAGTNELEVLELFLNHRTDTGQQACYLGVNVAKVMQVIEAPALDSPESATN
CCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCC
PCFMGIIPLRGLTVPVLDLGKWLGLDVVRHKHDVIMVTQFSGTTTGFLVSGVTDIHRVGW
CEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCHHHHHHCCC
QSVQPPGRFLAGIGADSVVGIVKMDDKFIQLVDLEHIIADLDASTRGQVGTGVTAPRRYK
CCCCCCHHHEECCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
AIVSDDSPSIRNMLVANLKAANIEPMIATNGQEALTMLRAEAARAEEENRPLSDFVDILI
EEECCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SDIEMPLMDGLSLTKTIKQDPLTRNVPVILYSSLITPELRHKGESVGADDQISKPDLASM
HHHCHHHHCCCHHHHHHHHCCCCCCCHHEEHHHHCCHHHHHCCCCCCCCCCCCCCCHHHH
AQRIISLLQEKERPA
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSEHNILLEAGTNELEVLELFLNHRTDTGQQACYLGVNVAKVMQVIEAPALDSPESATN
CCCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCC
PCFMGIIPLRGLTVPVLDLGKWLGLDVVRHKHDVIMVTQFSGTTTGFLVSGVTDIHRVGW
CEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCHHHHHHCCC
QSVQPPGRFLAGIGADSVVGIVKMDDKFIQLVDLEHIIADLDASTRGQVGTGVTAPRRYK
CCCCCCHHHEECCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
AIVSDDSPSIRNMLVANLKAANIEPMIATNGQEALTMLRAEAARAEEENRPLSDFVDILI
EEECCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SDIEMPLMDGLSLTKTIKQDPLTRNVPVILYSSLITPELRHKGESVGADDQISKPDLASM
HHHCHHHHCCCHHHHHHHHCCCCCCCHHEEHHHHCCHHHHHCCCCCCCCCCCCCCCHHHH
AQRIISLLQEKERPA
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8169223; 9384377; 8169224 [H]