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The map label for this gene is mltB [C]

Identifier: 78358105

GI number: 78358105

Start: 3058083

End: 3059138

Strand: Direct

Name: mltB [C]

Synonym: Dde_3065

Alternate gene names: 78358105

Gene position: 3058083-3059138 (Clockwise)

Preceding gene: 78358103

Following gene: 78358106

Centisome position: 81.98

GC content: 60.8

Gene sequence:

>1056_bases
ATGACTTCAATGCTCCGGGCAATCTGCTTATGTTTGCTGCTGCTGTGCGCCGCACCGCAGGCACGGGCAGGCACAGCTGC
GCAACAGCAGACAAATGACGCAACACTGCTTGCCAGCGCACAGCTTTCACCCCGGCAGGAACACATGCGCACGGCGGACA
CCCTGCGCGCCCAGTGCGACCCGCACAGCATAGTGGAACAGGCTGGCTGGCTGCCGCTGGCCACCCGCCTGATACGCGAC
GGGTTCGACGCAGAGCACATCATCATGCTGTACGCGCGCATGGGCGAATCCTATTCACCCGCCCCCATGGCACGCAAAAT
TTCGGCCCTCTACCGCATCAAATTTCCGCCGCCTGCACCCGCAAAATCCAAAGACACCGGAAAAAAAGCGCCCGCCCCGC
CACCCGTATACCCCGGTGTGGTCACCAGCGCCAATGTAGAAAAAGCGGCCGCTTTCATGCGGCAACACAGTGCGCCGCTG
CAGGCGGCCCGGCAGCGGTTCGGCATTCCGCCCGAGGTGGCCACGGGGCTGCTTTTTGTGGAAACACGGCTGGGCGCGTA
TCTGGGCAGCGCCGCGGCTCTGCACAATCTTTCTTCGCTGGCGGCCACCAACAGCACCGCCATAATGGCCGGCAGTCTGG
GCAGTATAGACCTGAGCAAAGCCGACCGCAGAACCTGGGCGGACAAGCGCACCCGCGAAAAATCCGACTGGGCCTATGAA
GAGCTTAAAGCGCTGCTCAGCTGGTCGCAGCAGCACAATCTGGACCCCGTTGCCATGCCCGGTTCGGTATACGGTGCCGT
GGGTCTGTGTCAGTTCATGCCTTCCAACATTCCCCGTTTCGGGGCGGACGGCGACGGCAACGGCAAAGTGAACCTGTTCA
GCGTGCCCGATGCGGTATTCAGCCTGTCGCGGTATCTTAGCGAACATGGCTGGAAAGAAGGCATCAGCCGGAAAAAACAA
CAGAAAGTGCTCATGCATTATAATAAAAGCACCCGCTATGCCAACACCATACTGGCCTTGGCCGATGAGCTGCGCAAACA
TGCGCAGGACCGGTAG

Upstream 100 bases:

>100_bases
CACCGTATTTCCCTTTGCGGTACCCGTTGCGATAAAAGCGCGGGCGGCGTAGTATAGACAGTACACGACTCTATAAATCA
GAATTTACAGGAATCATACA

Downstream 100 bases:

>100_bases
GTCTGCGGCGGGCGCAGGACGGCGGCATGAAAAATAATACAAGCGGGCATGAGACAGTACAGTGTATAACTGACAATGGC
GAAGACATAGCGCTAATCTG

Product: membrane-bound lytic murein transglycosylase B-like

Products: Muramic Acid Residue [C]

Alternate protein names: Membrane-Bound Lytic Murein Transglycosylase B-Like Protein; Lytic Murein Transglycosylase; Membrane-Bound Lytic Murein Transglycosylase B; Membrane-Bound Lytic Murein Transglycosylase B-Like; Murein Hydrolase B; Soluble Lytic Transglycosylase B; Transglycosylase Domain Protein; Transglycosylase Domain-Containing Protein; Murein Transglycosylase; Membrane-Bound Lytic Murein Transglycosylase B Protein

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTSMLRAICLCLLLLCAAPQARAGTAAQQQTNDATLLASAQLSPRQEHMRTADTLRAQCDPHSIVEQAGWLPLATRLIRD
GFDAEHIIMLYARMGESYSPAPMARKISALYRIKFPPPAPAKSKDTGKKAPAPPPVYPGVVTSANVEKAAAFMRQHSAPL
QAARQRFGIPPEVATGLLFVETRLGAYLGSAAALHNLSSLAATNSTAIMAGSLGSIDLSKADRRTWADKRTREKSDWAYE
ELKALLSWSQQHNLDPVAMPGSVYGAVGLCQFMPSNIPRFGADGDGNGKVNLFSVPDAVFSLSRYLSEHGWKEGISRKKQ
QKVLMHYNKSTRYANTILALADELRKHAQDR

Sequences:

>Translated_351_residues
MTSMLRAICLCLLLLCAAPQARAGTAAQQQTNDATLLASAQLSPRQEHMRTADTLRAQCDPHSIVEQAGWLPLATRLIRD
GFDAEHIIMLYARMGESYSPAPMARKISALYRIKFPPPAPAKSKDTGKKAPAPPPVYPGVVTSANVEKAAAFMRQHSAPL
QAARQRFGIPPEVATGLLFVETRLGAYLGSAAALHNLSSLAATNSTAIMAGSLGSIDLSKADRRTWADKRTREKSDWAYE
ELKALLSWSQQHNLDPVAMPGSVYGAVGLCQFMPSNIPRFGADGDGNGKVNLFSVPDAVFSLSRYLSEHGWKEGISRKKQ
QKVLMHYNKSTRYANTILALADELRKHAQDR
>Mature_350_residues
TSMLRAICLCLLLLCAAPQARAGTAAQQQTNDATLLASAQLSPRQEHMRTADTLRAQCDPHSIVEQAGWLPLATRLIRDG
FDAEHIIMLYARMGESYSPAPMARKISALYRIKFPPPAPAKSKDTGKKAPAPPPVYPGVVTSANVEKAAAFMRQHSAPLQ
AARQRFGIPPEVATGLLFVETRLGAYLGSAAALHNLSSLAATNSTAIMAGSLGSIDLSKADRRTWADKRTREKSDWAYEE
LKALLSWSQQHNLDPVAMPGSVYGAVGLCQFMPSNIPRFGADGDGNGKVNLFSVPDAVFSLSRYLSEHGWKEGISRKKQQ
KVLMHYNKSTRYANTILALADELRKHAQDR

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor And Exposed To The Periplasmic Protein Side [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789053, Length=175, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 38253; Mature: 38122

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSMLRAICLCLLLLCAAPQARAGTAAQQQTNDATLLASAQLSPRQEHMRTADTLRAQCD
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
PHSIVEQAGWLPLATRLIRDGFDAEHIIMLYARMGESYSPAPMARKISALYRIKFPPPAP
HHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCC
AKSKDTGKKAPAPPPVYPGVVTSANVEKAAAFMRQHSAPLQAARQRFGIPPEVATGLLFV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHH
ETRLGAYLGSAAALHNLSSLAATNSTAIMAGSLGSIDLSKADRRTWADKRTREKSDWAYE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
ELKALLSWSQQHNLDPVAMPGSVYGAVGLCQFMPSNIPRFGADGDGNGKVNLFSVPDAVF
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHH
SLSRYLSEHGWKEGISRKKQQKVLMHYNKSTRYANTILALADELRKHAQDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSMLRAICLCLLLLCAAPQARAGTAAQQQTNDATLLASAQLSPRQEHMRTADTLRAQCD
HHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
PHSIVEQAGWLPLATRLIRDGFDAEHIIMLYARMGESYSPAPMARKISALYRIKFPPPAP
HHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCC
AKSKDTGKKAPAPPPVYPGVVTSANVEKAAAFMRQHSAPLQAARQRFGIPPEVATGLLFV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHH
ETRLGAYLGSAAALHNLSSLAATNSTAIMAGSLGSIDLSKADRRTWADKRTREKSDWAYE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
ELKALLSWSQQHNLDPVAMPGSVYGAVGLCQFMPSNIPRFGADGDGNGKVNLFSVPDAVF
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHH
SLSRYLSEHGWKEGISRKKQQKVLMHYNKSTRYANTILALADELRKHAQDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA