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The map label for this gene is yqiR [H]

Identifier: 78358091

GI number: 78358091

Start: 3041163

End: 3042560

Strand: Reverse

Name: yqiR [H]

Synonym: Dde_3051

Alternate gene names: 78358091

Gene position: 3042560-3041163 (Counterclockwise)

Preceding gene: 78358096

Following gene: 78358090

Centisome position: 81.56

GC content: 48.28

Gene sequence:

>1398_bases
ATGCTTGAAGATATTTATGGTCACGATCTCAAGCAACTAGTGAATTTTCAGCGCAAAATTATAGACCTATGCGCGGACGC
TCTGATGGTAGTCAACAAGGAGGGGCGGCTTATTTACATTAATGAAAGCTTTAAAGAGCTTCATGGCTTAGGCGAAGAAG
TGCTGGGAGAGCCGGTAAGCAACATAATTGATAATACCCGGTTAAATATCGTCGCCCAGACAGGTATCGCAGAGCATGAT
TGTCTTCAGGAAATTGAGAACCACTCGTTTATAGTCTCGCGCATACCGTTTTACGAGGATGGAAACTGCATCGGTGCAGT
CGGGATGATCCGTTTCCGGCATGTGGATGAAATTCAAAAGCTCACAGAGAATATTAAAGAGCTTAAAAACGAAATTGAAA
GGTTACGCAAAAGCAAAAAAGCAAGCGATGAAGCCGAATACACTTTCAGCCACATTCCGGGAATTGCCCCCGCAGCCAGA
GAGGCAAAAAACAAAGCCATGCTGGCCGCCCCGCGGAACGTGACGGTTTTGTTACGCGGAGAATCCGGTGTGGGTAAGGA
AGTATATTCCCAGAGCATTCACAATTTCAGCCAACGTTGTGATGGTCCGTTTATACATCTCAACTGCAGCGCCATTGCCG
AGCACCTGATCGAATCTGAACTGTTCGGCTACGAAGAAGGCGCCTTTACCGGAGCCCGCAAGGGCGGACGCAGAGGCATG
TTTGAACAGGCCGACAAAGGCACAATTTTTCTGGATGAAATTGGTGATATGCCGCTTGCAGCGCAGGTTAAGCTGCTGCG
TGTAATTCAAGAGGGCAAAGTCAGCCGCATAGGAAGTGAAAAGATCACAAAGGTTGATGTCCGGATTATTGCTGCAACAA
ACCGGAATCTTGAAGAAATGGTGAAAGAAAAGACCTTCAGGGAAGACCTGTTCTATCGCCTGAACGTTATCCCCATTAAA
CTGCCTGCCCTGCGCCACGCGGTTGAGGAAATTCCGATATTAGCCAAGCGCATCTGGAAGCGGATGTCCCGGAAAAACGG
CATGTTCCATAAGTACCTTAACAGCAGCGCCCTGATCGCCCTGCAAGAATACCCGTGGCCGGGGAATGTCCGGGAATTAC
AGAACTTTTTGGAACGCTGCATGATAATGTCGCGCGAAAACGATATCACTGCTGAAATCGTTAACACTGTTCTTCAAAAC
GGTGTGGCATGTGATTTGATGCAACCGGAAGATGCTCTTGAACTGTTACCTCTTGCAGAACTGGTTGAGAAGACCGAGCT
TCAGGCCATATCCCGTGCTTTGAGCGCCGCCAACGGTAACCGTTCCGCCGCAGCGCGCAGACTCGGGATAACCCGCCCTC
TGCTCTATAAAAAGATGATTAAATACGGACTTAAATAA

Upstream 100 bases:

>100_bases
CTCTGAAGCACCCTGTCACGCTTGTGACAGCTGTCACAAAAGGGAGCAGTTTTTAAACTCAGCTGGCGAGTCACACCTTT
CAGACAGGAGGAATACTGCG

Downstream 100 bases:

>100_bases
CCCCTTGAAATAGGGATAGCCGGTTTGCCAGTCTGACAGGCATACCGGCGCGGGCGTTTCGCCCGCCTGCTGTCACAGAA
TGCGAACTGCGGCCTCTGTT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MLEDIYGHDLKQLVNFQRKIIDLCADALMVVNKEGRLIYINESFKELHGLGEEVLGEPVSNIIDNTRLNIVAQTGIAEHD
CLQEIENHSFIVSRIPFYEDGNCIGAVGMIRFRHVDEIQKLTENIKELKNEIERLRKSKKASDEAEYTFSHIPGIAPAAR
EAKNKAMLAAPRNVTVLLRGESGVGKEVYSQSIHNFSQRCDGPFIHLNCSAIAEHLIESELFGYEEGAFTGARKGGRRGM
FEQADKGTIFLDEIGDMPLAAQVKLLRVIQEGKVSRIGSEKITKVDVRIIAATNRNLEEMVKEKTFREDLFYRLNVIPIK
LPALRHAVEEIPILAKRIWKRMSRKNGMFHKYLNSSALIALQEYPWPGNVRELQNFLERCMIMSRENDITAEIVNTVLQN
GVACDLMQPEDALELLPLAELVEKTELQAISRALSAANGNRSAAARRLGITRPLLYKKMIKYGLK

Sequences:

>Translated_465_residues
MLEDIYGHDLKQLVNFQRKIIDLCADALMVVNKEGRLIYINESFKELHGLGEEVLGEPVSNIIDNTRLNIVAQTGIAEHD
CLQEIENHSFIVSRIPFYEDGNCIGAVGMIRFRHVDEIQKLTENIKELKNEIERLRKSKKASDEAEYTFSHIPGIAPAAR
EAKNKAMLAAPRNVTVLLRGESGVGKEVYSQSIHNFSQRCDGPFIHLNCSAIAEHLIESELFGYEEGAFTGARKGGRRGM
FEQADKGTIFLDEIGDMPLAAQVKLLRVIQEGKVSRIGSEKITKVDVRIIAATNRNLEEMVKEKTFREDLFYRLNVIPIK
LPALRHAVEEIPILAKRIWKRMSRKNGMFHKYLNSSALIALQEYPWPGNVRELQNFLERCMIMSRENDITAEIVNTVLQN
GVACDLMQPEDALELLPLAELVEKTELQAISRALSAANGNRSAAARRLGITRPLLYKKMIKYGLK
>Mature_465_residues
MLEDIYGHDLKQLVNFQRKIIDLCADALMVVNKEGRLIYINESFKELHGLGEEVLGEPVSNIIDNTRLNIVAQTGIAEHD
CLQEIENHSFIVSRIPFYEDGNCIGAVGMIRFRHVDEIQKLTENIKELKNEIERLRKSKKASDEAEYTFSHIPGIAPAAR
EAKNKAMLAAPRNVTVLLRGESGVGKEVYSQSIHNFSQRCDGPFIHLNCSAIAEHLIESELFGYEEGAFTGARKGGRRGM
FEQADKGTIFLDEIGDMPLAAQVKLLRVIQEGKVSRIGSEKITKVDVRIIAATNRNLEEMVKEKTFREDLFYRLNVIPIK
LPALRHAVEEIPILAKRIWKRMSRKNGMFHKYLNSSALIALQEYPWPGNVRELQNFLERCMIMSRENDITAEIVNTVLQN
GVACDLMQPEDALELLPLAELVEKTELQAISRALSAANGNRSAAARRLGITRPLLYKKMIKYGLK

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=346, Percent_Identity=41.907514450867, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1790437, Length=311, Percent_Identity=44.3729903536978, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1789087, Length=358, Percent_Identity=41.340782122905, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI87082117, Length=308, Percent_Identity=43.8311688311688, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1788905, Length=300, Percent_Identity=41.3333333333333, Blast_Score=235, Evalue=6e-63,
Organism=Escherichia coli, GI1790299, Length=333, Percent_Identity=41.4414414414414, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1789233, Length=301, Percent_Identity=43.5215946843854, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1786524, Length=326, Percent_Identity=40.1840490797546, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=37.8548895899054, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1787583, Length=348, Percent_Identity=33.0459770114943, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI87081872, Length=309, Percent_Identity=39.4822006472492, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI87081858, Length=338, Percent_Identity=30.1775147928994, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789828, Length=232, Percent_Identity=34.4827586206897, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52538; Mature: 52538

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEDIYGHDLKQLVNFQRKIIDLCADALMVVNKEGRLIYINESFKELHGLGEEVLGEPVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHCCCHHHHCCHHH
NIIDNTRLNIVAQTGIAEHDCLQEIENHSFIVSRIPFYEDGNCIGAVGMIRFRHVDEIQK
HHHCCCCEEEEEECCCCHHHHHHHHCCCCEEEEECCEECCCCEEEHHHHHHHHHHHHHHH
LTENIKELKNEIERLRKSKKASDEAEYTFSHIPGIAPAAREAKNKAMLAAPRNVTVLLRG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCEEEECCCCEEEEEEC
ESGVGKEVYSQSIHNFSQRCDGPFIHLNCSAIAEHLIESELFGYEEGAFTGARKGGRRGM
CCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
FEQADKGTIFLDEIGDMPLAAQVKLLRVIQEGKVSRIGSEKITKVDVRIIAATNRNLEEM
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCHHEEEEEEEEEECCCCHHHH
VKEKTFREDLFYRLNVIPIKLPALRHAVEEIPILAKRIWKRMSRKNGMFHKYLNSSALIA
HHHHHHHHHHHHEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEE
LQEYPWPGNVRELQNFLERCMIMSRENDITAEIVNTVLQNGVACDLMQPEDALELLPLAE
EECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHH
LVEKTELQAISRALSAANGNRSAAARRLGITRPLLYKKMIKYGLK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEDIYGHDLKQLVNFQRKIIDLCADALMVVNKEGRLIYINESFKELHGLGEEVLGEPVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHCCCHHHHCCHHH
NIIDNTRLNIVAQTGIAEHDCLQEIENHSFIVSRIPFYEDGNCIGAVGMIRFRHVDEIQK
HHHCCCCEEEEEECCCCHHHHHHHHCCCCEEEEECCEECCCCEEEHHHHHHHHHHHHHHH
LTENIKELKNEIERLRKSKKASDEAEYTFSHIPGIAPAAREAKNKAMLAAPRNVTVLLRG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCEEEECCCCEEEEEEC
ESGVGKEVYSQSIHNFSQRCDGPFIHLNCSAIAEHLIESELFGYEEGAFTGARKGGRRGM
CCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
FEQADKGTIFLDEIGDMPLAAQVKLLRVIQEGKVSRIGSEKITKVDVRIIAATNRNLEEM
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCHHEEEEEEEEEECCCCHHHH
VKEKTFREDLFYRLNVIPIKLPALRHAVEEIPILAKRIWKRMSRKNGMFHKYLNSSALIA
HHHHHHHHHHHHEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEE
LQEYPWPGNVRELQNFLERCMIMSRENDITAEIVNTVLQNGVACDLMQPEDALELLPLAE
EECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHH
LVEKTELQAISRALSAANGNRSAAARRLGITRPLLYKKMIKYGLK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]