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The map label for this gene is trxA [H]

Identifier: 78357823

GI number: 78357823

Start: 2781342

End: 2781605

Strand: Direct

Name: trxA [H]

Synonym: Dde_2781

Alternate gene names: 78357823

Gene position: 2781342-2781605 (Clockwise)

Preceding gene: 78357822

Following gene: 78357824

Centisome position: 74.56

GC content: 50.76

Gene sequence:

>264_bases
ATGGTCGATCTAGGAGCTCACAGTTGCATCCCGTGCAAAATGATGGCTCCGATCATCAAGGAGCTGTCCGCTGAATATAG
CGGGAGAGCTGCCATTGTGTTCATCGATGTTTGGGAAAACCCTAACGTTCCGCCGCAATTCGGCCTTAGAGCCATTCCTA
CCCAGATATTCTATGACGCGGAAGGCAAGGAACGATTCCGGCACGAAGGCTTCATGGATAAGGAGTCCATCGTCGAAAAG
CTGAAAAAGCTTGGGGTGAACTAG

Upstream 100 bases:

>100_bases
TGTCACGGGCCAAAAAGAAACCCTCGCAAGCTCAGGCACAATCGTAGCAGACCTGATCTCAGGCGCTCCACAAACTGTGC
CCATTCCAGGGACAGTGACA

Downstream 100 bases:

>100_bases
TCAATGGACCAGATATTCATCCTCATCAATCAATGGATGACCGGCGGGGTACTGCTCGGAGCGTTGGGGTGCTTCCTTTG
GGGCATGGTCAGCGTTTTGT

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 87; Mature: 87

Protein sequence:

>87_residues
MVDLGAHSCIPCKMMAPIIKELSAEYSGRAAIVFIDVWENPNVPPQFGLRAIPTQIFYDAEGKERFRHEGFMDKESIVEK
LKKLGVN

Sequences:

>Translated_87_residues
MVDLGAHSCIPCKMMAPIIKELSAEYSGRAAIVFIDVWENPNVPPQFGLRAIPTQIFYDAEGKERFRHEGFMDKESIVEK
LKKLGVN
>Mature_87_residues
MVDLGAHSCIPCKMMAPIIKELSAEYSGRAAIVFIDVWENPNVPPQFGLRAIPTQIFYDAEGKERFRHEGFMDKESIVEK
LKKLGVN

Specific function: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=58, Percent_Identity=39.6551724137931, Blast_Score=62, Evalue=7e-12,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 9824; Mature: 9824

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDLGAHSCIPCKMMAPIIKELSAEYSGRAAIVFIDVWENPNVPPQFGLRAIPTQIFYDA
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEECCHHEEECC
EGKERFRHEGFMDKESIVEKLKKLGVN
CCHHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVDLGAHSCIPCKMMAPIIKELSAEYSGRAAIVFIDVWENPNVPPQFGLRAIPTQIFYDA
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEECCHHEEECC
EGKERFRHEGFMDKESIVEKLKKLGVN
CCHHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]